SMT201600215B - Derivati dello sterolo, metodo per preparare gli stessi, composizioni farmaceutiche contenenti gli stessi e loro uso per il trattamento del glioblastoma multiforme - Google Patents
Derivati dello sterolo, metodo per preparare gli stessi, composizioni farmaceutiche contenenti gli stessi e loro uso per il trattamento del glioblastoma multiformeInfo
- Publication number
- SMT201600215B SMT201600215B SM201600215T SM201600215T SMT201600215B SM T201600215 B SMT201600215 B SM T201600215B SM 201600215 T SM201600215 T SM 201600215T SM 201600215 T SM201600215 T SM 201600215T SM T201600215 B SMT201600215 B SM T201600215B
- Authority
- SM
- San Marino
- Prior art keywords
- same
- sterol
- derivatives
- preparing
- treatment
- Prior art date
Links
- 229930182558 Sterol Natural products 0.000 title 1
- 208000005017 glioblastoma Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003432 sterols Chemical class 0.000 title 1
- 235000003702 sterols Nutrition 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305518.8A EP2662382B1 (fr) | 2012-05-10 | 2012-05-10 | Dérivés de stérol, leur procédé de préparation, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement du glioblastome multiple |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201600215B true SMT201600215B (it) | 2016-08-31 |
Family
ID=46149353
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20180147T SMT201800147T1 (it) | 2012-05-10 | 2013-05-07 | Derivati dello sterolo e loro uso per il trattamento di patologie che coinvolgono cellule astrocitiche trasformate o per il trattamento di emopatie maligne |
| SM201600215T SMT201600215B (it) | 2012-05-10 | 2016-07-05 | Derivati dello sterolo, metodo per preparare gli stessi, composizioni farmaceutiche contenenti gli stessi e loro uso per il trattamento del glioblastoma multiforme |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20180147T SMT201800147T1 (it) | 2012-05-10 | 2013-05-07 | Derivati dello sterolo e loro uso per il trattamento di patologie che coinvolgono cellule astrocitiche trasformate o per il trattamento di emopatie maligne |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10800806B2 (it) |
| EP (2) | EP2662382B1 (it) |
| JP (1) | JP6270823B2 (it) |
| KR (1) | KR102160316B1 (it) |
| CN (1) | CN104302655B (it) |
| BR (1) | BR112014026948B1 (it) |
| CA (1) | CA2871714C (it) |
| CY (2) | CY1117723T1 (it) |
| DK (2) | DK2662382T3 (it) |
| ES (2) | ES2580331T3 (it) |
| HR (2) | HRP20180345T1 (it) |
| HU (2) | HUE029243T2 (it) |
| IN (1) | IN2014DN09437A (it) |
| LT (1) | LT2847204T (it) |
| ME (1) | ME02436B (it) |
| PL (2) | PL2662382T3 (it) |
| PT (2) | PT2662382T (it) |
| RS (2) | RS54926B1 (it) |
| RU (1) | RU2627710C2 (it) |
| SI (2) | SI2662382T1 (it) |
| SM (2) | SMT201800147T1 (it) |
| TR (1) | TR201802700T4 (it) |
| WO (1) | WO2013168096A1 (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3013048A1 (fr) * | 2013-11-12 | 2015-05-15 | Beta Innov | Derive de sterol, son procede de preparation, composition pharmaceutique le contenant et son utilisation pour le traitement du glioblastome multiforme |
| EP3593789A1 (fr) * | 2018-07-11 | 2020-01-15 | Beta Innov | Composition contenant un dérivé de 7beta-hydroxycholestérol et un véhicule lipidique, et son utilisation dans le traitement de pathologies néoplasiques |
| WO2022245122A1 (ko) * | 2021-05-18 | 2022-11-24 | 연세대학교 산학협력단 | 암의 예방, 개선 또는 치료용 조성물 |
| KR102689231B1 (ko) * | 2021-05-18 | 2024-07-30 | 연세대학교 산학협력단 | 암의 예방, 개선 또는 치료용 조성물 |
| WO2024030660A2 (en) * | 2022-08-04 | 2024-02-08 | University Of Massachusetts | Cholesterol-modified hyaluronic acids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9602100D0 (sv) | 1996-05-30 | 1996-05-30 | Magnus Axelson | New pharmaceuticals |
| JP2006503840A (ja) * | 2002-09-25 | 2006-02-02 | フォーブス メディ−テック インコーポレーテッド | ステロール及び／又はスタノール及び抗炎症剤の特定の種類を含有する新規構造体及び組成物、並びに、心血管疾患、その根底にある高脂血症を含む病気、及び原因又は症状の一部として炎症を有する他の障害の治療又は予防におけるそれらの使用 |
-
2012
- 2012-05-10 RS RS20160499A patent/RS54926B1/sr unknown
- 2012-05-10 HU HUE12305518A patent/HUE029243T2/en unknown
- 2012-05-10 PT PT123055188T patent/PT2662382T/pt unknown
- 2012-05-10 SI SI201230585A patent/SI2662382T1/sl unknown
- 2012-05-10 ME MEP-2016-134A patent/ME02436B/me unknown
- 2012-05-10 EP EP12305518.8A patent/EP2662382B1/fr active Active
- 2012-05-10 ES ES12305518.8T patent/ES2580331T3/es active Active
- 2012-05-10 PL PL12305518.8T patent/PL2662382T3/pl unknown
- 2012-05-10 DK DK12305518.8T patent/DK2662382T3/en active
-
2013
- 2013-05-07 BR BR112014026948-3A patent/BR112014026948B1/pt active IP Right Grant
- 2013-05-07 ES ES13729470.8T patent/ES2662123T3/es active Active
- 2013-05-07 US US14/399,336 patent/US10800806B2/en active Active
- 2013-05-07 JP JP2015510925A patent/JP6270823B2/ja active Active
- 2013-05-07 TR TR2018/02700T patent/TR201802700T4/tr unknown
- 2013-05-07 EP EP13729470.8A patent/EP2847204B1/en active Active
- 2013-05-07 CN CN201380023824.4A patent/CN104302655B/zh active Active
- 2013-05-07 WO PCT/IB2013/053669 patent/WO2013168096A1/en not_active Ceased
- 2013-05-07 SI SI201330962T patent/SI2847204T1/en unknown
- 2013-05-07 KR KR1020147034290A patent/KR102160316B1/ko active Active
- 2013-05-07 SM SM20180147T patent/SMT201800147T1/it unknown
- 2013-05-07 PL PL13729470T patent/PL2847204T3/pl unknown
- 2013-05-07 DK DK13729470.8T patent/DK2847204T3/en active
- 2013-05-07 RS RS20180237A patent/RS57065B1/sr unknown
- 2013-05-07 HU HUE13729470A patent/HUE037004T2/hu unknown
- 2013-05-07 CA CA2871714A patent/CA2871714C/en active Active
- 2013-05-07 PT PT137294708T patent/PT2847204T/pt unknown
- 2013-05-07 LT LTEP13729470.8T patent/LT2847204T/lt unknown
- 2013-05-07 IN IN9437DEN2014 patent/IN2014DN09437A/en unknown
- 2013-05-07 RU RU2014149705A patent/RU2627710C2/ru active
- 2013-05-07 HR HRP20180345TT patent/HRP20180345T1/hr unknown
-
2016
- 2016-06-07 HR HRP20160624TT patent/HRP20160624T1/hr unknown
- 2016-07-05 SM SM201600215T patent/SMT201600215B/it unknown
- 2016-07-05 CY CY20161100621T patent/CY1117723T1/el unknown
-
2018
- 2018-03-13 CY CY20181100306T patent/CY1120395T1/el unknown
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