HRP20180345T1 - Derivati sterola i njihova upotreba u liječenju bolesti koje uključuju transformirane astrocitne stanice, ili u liječenju zloćudnih hemopatija - Google Patents

Derivati sterola i njihova upotreba u liječenju bolesti koje uključuju transformirane astrocitne stanice, ili u liječenju zloćudnih hemopatija

Info

Publication number
HRP20180345T1
HRP20180345T1 HRP20180345TT HRP20180345T HRP20180345T1 HR P20180345 T1 HRP20180345 T1 HR P20180345T1 HR P20180345T T HRP20180345T T HR P20180345TT HR P20180345 T HRP20180345 T HR P20180345T HR P20180345 T1 HRP20180345 T1 HR P20180345T1
Authority
HR
Croatia
Prior art keywords
treating
diseases involving
sterol derivatives
astrocyte cells
malignant haemopathies
Prior art date
Application number
HRP20180345TT
Other languages
English (en)
Inventor
Ludovic Clarion
Marcel Mersel
Didier Petite
Original Assignee
Beta Innov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beta Innov filed Critical Beta Innov
Publication of HRP20180345T1 publication Critical patent/HRP20180345T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
HRP20180345TT 2012-05-10 2018-02-26 Derivati sterola i njihova upotreba u liječenju bolesti koje uključuju transformirane astrocitne stanice, ili u liječenju zloćudnih hemopatija HRP20180345T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12305518.8A EP2662382B1 (fr) 2012-05-10 2012-05-10 Dérivés de stérol, leur procédé de préparation, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement du glioblastome multiple
US201261656151P 2012-06-06 2012-06-06
EP13729470.8A EP2847204B1 (en) 2012-05-10 2013-05-07 Sterol derivatives and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies
PCT/IB2013/053669 WO2013168096A1 (en) 2012-05-10 2013-05-07 Sterol derivatives and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies

Publications (1)

Publication Number Publication Date
HRP20180345T1 true HRP20180345T1 (hr) 2018-06-01

Family

ID=46149353

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20160624TT HRP20160624T1 (hr) 2012-05-10 2016-06-07 Derivati sterola, postupci njihove pripreme, farmaceutski pripravci koji ih sadrže i njihova uporaba za liječenje multiplih glioblastoma
HRP20180345TT HRP20180345T1 (hr) 2012-05-10 2018-02-26 Derivati sterola i njihova upotreba u liječenju bolesti koje uključuju transformirane astrocitne stanice, ili u liječenju zloćudnih hemopatija

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HRP20160624TT HRP20160624T1 (hr) 2012-05-10 2016-06-07 Derivati sterola, postupci njihove pripreme, farmaceutski pripravci koji ih sadrže i njihova uporaba za liječenje multiplih glioblastoma

Country Status (24)

Country Link
US (1) US10800806B2 (hr)
EP (2) EP2662382B1 (hr)
JP (1) JP6270823B2 (hr)
KR (1) KR102160316B1 (hr)
CN (1) CN104302655B (hr)
BR (1) BR112014026948B1 (hr)
CA (1) CA2871714C (hr)
CY (2) CY1117723T1 (hr)
DK (2) DK2662382T3 (hr)
ES (2) ES2580331T3 (hr)
HK (2) HK1191654A1 (hr)
HR (2) HRP20160624T1 (hr)
HU (2) HUE029243T2 (hr)
IN (1) IN2014DN09437A (hr)
LT (1) LT2847204T (hr)
ME (1) ME02436B (hr)
PL (2) PL2662382T3 (hr)
PT (2) PT2662382T (hr)
RS (2) RS54926B1 (hr)
RU (1) RU2627710C2 (hr)
SI (2) SI2662382T1 (hr)
SM (1) SMT201600215B (hr)
TR (1) TR201802700T4 (hr)
WO (1) WO2013168096A1 (hr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3013048A1 (fr) * 2013-11-12 2015-05-15 Beta Innov Derive de sterol, son procede de preparation, composition pharmaceutique le contenant et son utilisation pour le traitement du glioblastome multiforme
EP3593789A1 (fr) * 2018-07-11 2020-01-15 Beta Innov Composition contenant un dérivé de 7beta-hydroxycholestérol et un véhicule lipidique, et son utilisation dans le traitement de pathologies néoplasiques
WO2022245122A1 (ko) * 2021-05-18 2022-11-24 연세대학교 산학협력단 암의 예방, 개선 또는 치료용 조성물
KR20220156177A (ko) * 2021-05-18 2022-11-25 연세대학교 산학협력단 암의 예방, 개선 또는 치료용 조성물
WO2024030660A2 (en) * 2022-08-04 2024-02-08 University Of Massachusetts Cholesterol-modified hyaluronic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9602100D0 (sv) * 1996-05-30 1996-05-30 Magnus Axelson New pharmaceuticals
CA2499817A1 (en) * 2002-09-25 2004-04-08 Forbes Medi-Tech Inc. Derivatives comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease

Also Published As

Publication number Publication date
RS54926B1 (sr) 2016-10-31
JP2015520146A (ja) 2015-07-16
EP2847204A1 (en) 2015-03-18
HK1191654A1 (zh) 2014-08-01
EP2847204B1 (en) 2017-12-13
SMT201600215B (it) 2016-08-31
PL2847204T3 (pl) 2018-06-29
CN104302655A (zh) 2015-01-21
US10800806B2 (en) 2020-10-13
PT2662382T (pt) 2016-07-13
US20150086615A1 (en) 2015-03-26
SI2662382T1 (sl) 2016-08-31
PL2662382T3 (pl) 2016-10-31
HUE037004T2 (hu) 2018-08-28
RU2014149705A (ru) 2016-07-10
KR102160316B1 (ko) 2020-09-25
LT2847204T (lt) 2018-03-26
HRP20160624T1 (hr) 2016-08-12
DK2662382T3 (en) 2016-06-27
TR201802700T4 (tr) 2018-03-21
BR112014026948B1 (pt) 2022-05-24
BR112014026948A2 (pt) 2017-06-27
CY1117723T1 (el) 2017-05-17
HK1207385A1 (en) 2016-01-29
WO2013168096A1 (en) 2013-11-14
CA2871714A1 (en) 2013-11-14
SI2847204T1 (en) 2018-05-31
RU2627710C2 (ru) 2017-08-10
PT2847204T (pt) 2018-03-21
CY1120395T1 (el) 2019-07-10
KR20150013254A (ko) 2015-02-04
ES2580331T3 (es) 2016-08-23
CN104302655B (zh) 2018-04-03
ES2662123T3 (es) 2018-04-05
EP2662382A1 (fr) 2013-11-13
HUE029243T2 (en) 2017-02-28
DK2847204T3 (en) 2018-03-12
ME02436B (me) 2016-09-20
EP2662382B1 (fr) 2016-04-06
RS57065B1 (sr) 2018-06-29
IN2014DN09437A (hr) 2015-07-17
JP6270823B2 (ja) 2018-01-31
CA2871714C (en) 2022-09-20

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