IN2014DN09437A - - Google Patents
Info
- Publication number
- IN2014DN09437A IN2014DN09437A IN9437DEN2014A IN2014DN09437A IN 2014DN09437 A IN2014DN09437 A IN 2014DN09437A IN 9437DEN2014 A IN9437DEN2014 A IN 9437DEN2014A IN 2014DN09437 A IN2014DN09437 A IN 2014DN09437A
- Authority
- IN
- India
- Prior art keywords
- relates
- neuroblastomas
- melanomas
- lymphomas
- cancers
- Prior art date
Links
- 201000010915 Glioblastoma multiforme Diseases 0.000 abstract 1
- 206010025323 Lymphomas Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010029260 Neuroblastoma Diseases 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- 210000001130 astrocyte Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000005017 glioblastoma Diseases 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 201000001441 melanoma Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to novel sterol derivatives the preparation method thereof pharmaceutical compositions containing them and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies. The invention in particular relates to the treatment of glioblastoma multiforme, as well as of other cancers such as lymphomas neuroblastomas and melanomas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305518.8A EP2662382B1 (en) | 2012-05-10 | 2012-05-10 | Sterol derivatives, method for preparing same, pharmaceutical compositions containing same and use thereof for the treatment of multiple glioblastomas |
| US201261656151P | 2012-06-06 | 2012-06-06 | |
| PCT/IB2013/053669 WO2013168096A1 (en) | 2012-05-10 | 2013-05-07 | Sterol derivatives and use thereof for treating diseases involving transformed astrocyte cells or for treating malignant haemopathies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN09437A true IN2014DN09437A (en) | 2015-07-17 |
Family
ID=46149353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN9437DEN2014 IN2014DN09437A (en) | 2012-05-10 | 2013-05-07 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10800806B2 (en) |
| EP (2) | EP2662382B1 (en) |
| JP (1) | JP6270823B2 (en) |
| KR (1) | KR102160316B1 (en) |
| CN (1) | CN104302655B (en) |
| BR (1) | BR112014026948B1 (en) |
| CA (1) | CA2871714C (en) |
| CY (2) | CY1117723T1 (en) |
| DK (2) | DK2662382T3 (en) |
| ES (2) | ES2580331T3 (en) |
| HR (2) | HRP20180345T1 (en) |
| HU (2) | HUE029243T2 (en) |
| IN (1) | IN2014DN09437A (en) |
| LT (1) | LT2847204T (en) |
| ME (1) | ME02436B (en) |
| PL (2) | PL2662382T3 (en) |
| PT (2) | PT2662382T (en) |
| RS (2) | RS54926B1 (en) |
| RU (1) | RU2627710C2 (en) |
| SI (2) | SI2662382T1 (en) |
| SM (2) | SMT201800147T1 (en) |
| TR (1) | TR201802700T4 (en) |
| WO (1) | WO2013168096A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3013048A1 (en) * | 2013-11-12 | 2015-05-15 | Beta Innov | STEROL DERIVATIVE, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE THEREOF FOR THE TREATMENT OF MULTIMEDIA GLIOBLASTOMA |
| EP3593789A1 (en) | 2018-07-11 | 2020-01-15 | Beta Innov | Composition containing a 7-beta-hydroxycholesterol derivative and a lipid carrier, and use thereof in the treatment of neoplastic pathologies |
| KR102748745B1 (en) * | 2021-05-18 | 2025-01-03 | 연세대학교 산학협력단 | A composition for preventing, alleviating or treating cancer |
| KR102689231B1 (en) * | 2021-05-18 | 2024-07-30 | 연세대학교 산학협력단 | A composition for preventing, alleviating or treating cancer |
| WO2024030660A2 (en) * | 2022-08-04 | 2024-02-08 | University Of Massachusetts | Cholesterol-modified hyaluronic acids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9602100D0 (en) * | 1996-05-30 | 1996-05-30 | Magnus Axelson | New pharmaceuticals |
| KR20050084572A (en) * | 2002-09-25 | 2005-08-26 | 포비스 메디-테크 인코포레이티드 | Derivatives comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease |
-
2012
- 2012-05-10 DK DK12305518.8T patent/DK2662382T3/en active
- 2012-05-10 SI SI201230585A patent/SI2662382T1/en unknown
- 2012-05-10 RS RS20160499A patent/RS54926B1/en unknown
- 2012-05-10 EP EP12305518.8A patent/EP2662382B1/en active Active
- 2012-05-10 ES ES12305518.8T patent/ES2580331T3/en active Active
- 2012-05-10 ME MEP-2016-134A patent/ME02436B/en unknown
- 2012-05-10 PT PT123055188T patent/PT2662382T/en unknown
- 2012-05-10 PL PL12305518.8T patent/PL2662382T3/en unknown
- 2012-05-10 HU HUE12305518A patent/HUE029243T2/en unknown
-
2013
- 2013-05-07 TR TR2018/02700T patent/TR201802700T4/en unknown
- 2013-05-07 WO PCT/IB2013/053669 patent/WO2013168096A1/en active Application Filing
- 2013-05-07 US US14/399,336 patent/US10800806B2/en active Active
- 2013-05-07 ES ES13729470.8T patent/ES2662123T3/en active Active
- 2013-05-07 JP JP2015510925A patent/JP6270823B2/en active Active
- 2013-05-07 CA CA2871714A patent/CA2871714C/en active Active
- 2013-05-07 HR HRP20180345TT patent/HRP20180345T1/en unknown
- 2013-05-07 IN IN9437DEN2014 patent/IN2014DN09437A/en unknown
- 2013-05-07 HU HUE13729470A patent/HUE037004T2/en unknown
- 2013-05-07 KR KR1020147034290A patent/KR102160316B1/en active Active
- 2013-05-07 CN CN201380023824.4A patent/CN104302655B/en active Active
- 2013-05-07 SM SM20180147T patent/SMT201800147T1/en unknown
- 2013-05-07 LT LTEP13729470.8T patent/LT2847204T/en unknown
- 2013-05-07 DK DK13729470.8T patent/DK2847204T3/en active
- 2013-05-07 PT PT137294708T patent/PT2847204T/en unknown
- 2013-05-07 BR BR112014026948-3A patent/BR112014026948B1/en active IP Right Grant
- 2013-05-07 RS RS20180237A patent/RS57065B1/en unknown
- 2013-05-07 PL PL13729470T patent/PL2847204T3/en unknown
- 2013-05-07 SI SI201330962T patent/SI2847204T1/en unknown
- 2013-05-07 EP EP13729470.8A patent/EP2847204B1/en active Active
- 2013-05-07 RU RU2014149705A patent/RU2627710C2/en active
-
2016
- 2016-06-07 HR HRP20160624TT patent/HRP20160624T1/en unknown
- 2016-07-05 CY CY20161100621T patent/CY1117723T1/en unknown
- 2016-07-05 SM SM201600215T patent/SMT201600215B/en unknown
-
2018
- 2018-03-13 CY CY20181100306T patent/CY1120395T1/en unknown
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