PL2922541T3 - Hydrazony pirydylowe do leczenia gruźlicy i chorób pokrewnych - Google Patents
Hydrazony pirydylowe do leczenia gruźlicy i chorób pokrewnychInfo
- Publication number
- PL2922541T3 PL2922541T3 PL13811632T PL13811632T PL2922541T3 PL 2922541 T3 PL2922541 T3 PL 2922541T3 PL 13811632 T PL13811632 T PL 13811632T PL 13811632 T PL13811632 T PL 13811632T PL 2922541 T3 PL2922541 T3 PL 2922541T3
- Authority
- PL
- Poland
- Prior art keywords
- hydrazones
- tuberculosis
- pyridyl
- treatment
- related diseases
- Prior art date
Links
- -1 Pyridyl hydrazones Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 201000008827 tuberculosis Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
- C07D213/77—Hydrazine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT106652A PT106652A (pt) | 2012-11-20 | 2012-11-20 | Piridil hidrazonas para o tratamento de tuberculose e doenças relacionadas |
| EP13811632.2A EP2922541B1 (en) | 2012-11-20 | 2013-11-20 | Pyridyl hydrazones for the treatment of tuberculosis and related diseases |
| PCT/PT2013/000068 WO2014081324A1 (en) | 2012-11-20 | 2013-11-20 | Pyridyl hydrazones for the treatment of tuberculosis and related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2922541T3 true PL2922541T3 (pl) | 2019-10-31 |
Family
ID=49876952
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13811632T PL2922541T3 (pl) | 2012-11-20 | 2013-11-20 | Hydrazony pirydylowe do leczenia gruźlicy i chorób pokrewnych |
| PL19167996T PL3539543T3 (pl) | 2012-11-20 | 2013-11-20 | Pirydylohydrazyny w leczeniu gruźlicy i chorób pokrewnych |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19167996T PL3539543T3 (pl) | 2012-11-20 | 2013-11-20 | Pirydylohydrazyny w leczeniu gruźlicy i chorób pokrewnych |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9593103B2 (pl) |
| EP (2) | EP3539543B1 (pl) |
| BR (1) | BR112015011606A2 (pl) |
| CY (2) | CY1121861T1 (pl) |
| DK (1) | DK2922541T3 (pl) |
| ES (2) | ES2741434T3 (pl) |
| HR (2) | HRP20211767T1 (pl) |
| HU (2) | HUE056531T2 (pl) |
| LT (2) | LT3539543T (pl) |
| MA (1) | MA38206B1 (pl) |
| PL (2) | PL2922541T3 (pl) |
| PT (3) | PT106652A (pl) |
| RS (2) | RS59224B1 (pl) |
| SI (2) | SI3539543T1 (pl) |
| WO (1) | WO2014081324A1 (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115590857B (zh) * | 2021-07-08 | 2024-11-05 | 中国医学科学院药物研究所 | 化合物t0349在制备抗结核分枝杆菌药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716131A1 (de) * | 1987-05-14 | 1988-12-01 | Forsch Borstel Inst Fuer Exper | Substituierte 2-acylpyridin-(alpha)-(n)-hetarylhydrazone sowie diese enthaltende arzneimittel |
| US8865901B2 (en) * | 2009-10-02 | 2014-10-21 | Fred Hutchinson Cancer Research Center | Gain-of-function Bcl-2 inhibitors |
| EP2311457A1 (en) | 2009-10-19 | 2011-04-20 | Forschungszentrum Borstel | Pharmaceutical compositions for treating infections with drug resistant mycobacteria |
-
2012
- 2012-11-20 PT PT106652A patent/PT106652A/pt unknown
-
2013
- 2013-11-20 WO PCT/PT2013/000068 patent/WO2014081324A1/en not_active Ceased
- 2013-11-20 PL PL13811632T patent/PL2922541T3/pl unknown
- 2013-11-20 HR HRP20211767TT patent/HRP20211767T1/hr unknown
- 2013-11-20 ES ES13811632T patent/ES2741434T3/es active Active
- 2013-11-20 DK DK13811632.2T patent/DK2922541T3/da active
- 2013-11-20 HU HUE19167996A patent/HUE056531T2/hu unknown
- 2013-11-20 ES ES19167996T patent/ES2899437T3/es active Active
- 2013-11-20 SI SI201331949T patent/SI3539543T1/sl unknown
- 2013-11-20 RS RSP20191006 patent/RS59224B1/sr unknown
- 2013-11-20 EP EP19167996.8A patent/EP3539543B1/en active Active
- 2013-11-20 SI SI201331543T patent/SI2922541T1/sl unknown
- 2013-11-20 BR BR112015011606A patent/BR112015011606A2/pt not_active Application Discontinuation
- 2013-11-20 MA MA38206A patent/MA38206B1/fr unknown
- 2013-11-20 RS RS20211433A patent/RS62579B1/sr unknown
- 2013-11-20 HR HRP20191402 patent/HRP20191402T1/hr unknown
- 2013-11-20 LT LTEP19167996.8T patent/LT3539543T/lt unknown
- 2013-11-20 PT PT191679968T patent/PT3539543T/pt unknown
- 2013-11-20 PL PL19167996T patent/PL3539543T3/pl unknown
- 2013-11-20 EP EP13811632.2A patent/EP2922541B1/en active Active
- 2013-11-20 HU HUE13811632A patent/HUE045502T2/hu unknown
- 2013-11-20 LT LTEP13811632.2T patent/LT2922541T/lt unknown
- 2013-11-20 PT PT13811632T patent/PT2922541T/pt unknown
- 2013-11-20 US US14/646,197 patent/US9593103B2/en active Active
-
2019
- 2019-08-06 CY CY20191100833T patent/CY1121861T1/el unknown
-
2021
- 2021-11-26 CY CY20211101030T patent/CY1124836T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2741434T3 (es) | 2020-02-11 |
| US9593103B2 (en) | 2017-03-14 |
| EP2922541B1 (en) | 2019-05-22 |
| ES2899437T3 (es) | 2022-03-11 |
| LT2922541T (lt) | 2019-09-25 |
| WO2014081324A1 (en) | 2014-05-30 |
| RS59224B1 (sr) | 2019-10-31 |
| US20150284374A1 (en) | 2015-10-08 |
| EP3539543B1 (en) | 2021-09-01 |
| MA38206B1 (fr) | 2019-03-29 |
| SI3539543T1 (sl) | 2022-01-31 |
| EP3539543A1 (en) | 2019-09-18 |
| LT3539543T (lt) | 2021-12-27 |
| CY1121861T1 (el) | 2020-07-31 |
| HRP20211767T1 (hr) | 2022-02-18 |
| SI2922541T1 (sl) | 2019-10-30 |
| DK2922541T3 (da) | 2019-08-12 |
| PT106652A (pt) | 2014-05-20 |
| RS62579B1 (sr) | 2021-12-31 |
| PL3539543T3 (pl) | 2022-01-10 |
| EP2922541A1 (en) | 2015-09-30 |
| HUE056531T2 (hu) | 2022-02-28 |
| CY1124836T1 (el) | 2022-11-25 |
| BR112015011606A2 (pt) | 2017-07-11 |
| HRP20191402T1 (hr) | 2019-11-15 |
| MA38206A1 (fr) | 2017-12-29 |
| HUE045502T2 (hu) | 2019-12-30 |
| PT2922541T (pt) | 2019-08-26 |
| PT3539543T (pt) | 2021-11-22 |
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