HUE056531T2 - Piridil-hidrazonok a tuberkulózis és kapcsolódó betegségei kezelésére - Google Patents
Piridil-hidrazonok a tuberkulózis és kapcsolódó betegségei kezeléséreInfo
- Publication number
- HUE056531T2 HUE056531T2 HUE19167996A HUE19167996A HUE056531T2 HU E056531 T2 HUE056531 T2 HU E056531T2 HU E19167996 A HUE19167996 A HU E19167996A HU E19167996 A HUE19167996 A HU E19167996A HU E056531 T2 HUE056531 T2 HU E056531T2
- Authority
- HU
- Hungary
- Prior art keywords
- hydrazones
- tuberculosis
- pyridyl
- treatment
- related diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
- C07D213/77—Hydrazine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT2012106652 | 2012-11-20 | ||
| PT106652A PT106652A (pt) | 2012-11-20 | 2012-11-20 | Piridil hidrazonas para o tratamento de tuberculose e doenças relacionadas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE056531T2 true HUE056531T2 (hu) | 2022-02-28 |
Family
ID=49876952
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE13811632A HUE045502T2 (hu) | 2012-11-20 | 2013-11-20 | Piridil hidrazonok tuberkulózis és azzal összefüggõ betegségek kezelésére |
| HUE19167996A HUE056531T2 (hu) | 2012-11-20 | 2013-11-20 | Piridil-hidrazonok a tuberkulózis és kapcsolódó betegségei kezelésére |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE13811632A HUE045502T2 (hu) | 2012-11-20 | 2013-11-20 | Piridil hidrazonok tuberkulózis és azzal összefüggõ betegségek kezelésére |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9593103B2 (hu) |
| EP (2) | EP3539543B1 (hu) |
| BR (1) | BR112015011606A2 (hu) |
| CY (2) | CY1121861T1 (hu) |
| DK (1) | DK2922541T3 (hu) |
| ES (2) | ES2741434T3 (hu) |
| HR (2) | HRP20211767T1 (hu) |
| HU (2) | HUE045502T2 (hu) |
| LT (2) | LT2922541T (hu) |
| MA (1) | MA38206B1 (hu) |
| PL (2) | PL2922541T3 (hu) |
| PT (3) | PT106652A (hu) |
| RS (2) | RS62579B1 (hu) |
| SI (2) | SI3539543T1 (hu) |
| WO (1) | WO2014081324A1 (hu) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115590857A (zh) * | 2021-07-08 | 2023-01-13 | 中国医学科学院药物研究所（Cn） | 化合物t0349在制备抗结核分枝杆菌药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716131A1 (de) * | 1987-05-14 | 1988-12-01 | Forsch Borstel Inst Fuer Exper | Substituierte 2-acylpyridin-(alpha)-(n)-hetarylhydrazone sowie diese enthaltende arzneimittel |
| US8865901B2 (en) * | 2009-10-02 | 2014-10-21 | Fred Hutchinson Cancer Research Center | Gain-of-function Bcl-2 inhibitors |
| EP2311457A1 (en) * | 2009-10-19 | 2011-04-20 | Forschungszentrum Borstel | Pharmaceutical compositions for treating infections with drug resistant mycobacteria |
-
2012
- 2012-11-20 PT PT106652A patent/PT106652A/pt unknown
-
2013
- 2013-11-20 DK DK13811632.2T patent/DK2922541T3/da active
- 2013-11-20 EP EP19167996.8A patent/EP3539543B1/en active Active
- 2013-11-20 EP EP13811632.2A patent/EP2922541B1/en active Active
- 2013-11-20 RS RS20211433A patent/RS62579B1/sr unknown
- 2013-11-20 US US14/646,197 patent/US9593103B2/en active Active
- 2013-11-20 PT PT191679968T patent/PT3539543T/pt unknown
- 2013-11-20 RS RSP20191006 patent/RS59224B1/sr unknown
- 2013-11-20 WO PCT/PT2013/000068 patent/WO2014081324A1/en active Application Filing
- 2013-11-20 MA MA38206A patent/MA38206B1/fr unknown
- 2013-11-20 ES ES13811632T patent/ES2741434T3/es active Active
- 2013-11-20 SI SI201331949T patent/SI3539543T1/sl unknown
- 2013-11-20 LT LTEP13811632.2T patent/LT2922541T/lt unknown
- 2013-11-20 PL PL13811632T patent/PL2922541T3/pl unknown
- 2013-11-20 BR BR112015011606A patent/BR112015011606A2/pt not_active Application Discontinuation
- 2013-11-20 HU HUE13811632A patent/HUE045502T2/hu unknown
- 2013-11-20 ES ES19167996T patent/ES2899437T3/es active Active
- 2013-11-20 HR HRP20211767TT patent/HRP20211767T1/hr unknown
- 2013-11-20 PL PL19167996T patent/PL3539543T3/pl unknown
- 2013-11-20 SI SI201331543T patent/SI2922541T1/sl unknown
- 2013-11-20 LT LTEP19167996.8T patent/LT3539543T/lt unknown
- 2013-11-20 PT PT13811632T patent/PT2922541T/pt unknown
- 2013-11-20 HU HUE19167996A patent/HUE056531T2/hu unknown
-
2019
- 2019-08-02 HR HRP20191402 patent/HRP20191402T1/hr unknown
- 2019-08-06 CY CY20191100833T patent/CY1121861T1/el unknown
-
2021
- 2021-11-26 CY CY20211101030T patent/CY1124836T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA38206A1 (fr) | 2017-12-29 |
| BR112015011606A2 (pt) | 2017-07-11 |
| CY1124836T1 (el) | 2022-11-25 |
| SI3539543T1 (sl) | 2022-01-31 |
| EP2922541B1 (en) | 2019-05-22 |
| RS62579B1 (sr) | 2021-12-31 |
| PL2922541T3 (pl) | 2019-10-31 |
| HRP20211767T1 (hr) | 2022-02-18 |
| RS59224B1 (sr) | 2019-10-31 |
| PT2922541T (pt) | 2019-08-26 |
| LT2922541T (lt) | 2019-09-25 |
| PT106652A (pt) | 2014-05-20 |
| MA38206B1 (fr) | 2019-03-29 |
| CY1121861T1 (el) | 2020-07-31 |
| HUE045502T2 (hu) | 2019-12-30 |
| PL3539543T3 (pl) | 2022-01-10 |
| DK2922541T3 (da) | 2019-08-12 |
| US9593103B2 (en) | 2017-03-14 |
| ES2899437T3 (es) | 2022-03-11 |
| EP2922541A1 (en) | 2015-09-30 |
| EP3539543A1 (en) | 2019-09-18 |
| LT3539543T (lt) | 2021-12-27 |
| ES2741434T3 (es) | 2020-02-11 |
| PT3539543T (pt) | 2021-11-22 |
| EP3539543B1 (en) | 2021-09-01 |
| SI2922541T1 (sl) | 2019-10-30 |
| US20150284374A1 (en) | 2015-10-08 |
| HRP20191402T1 (hr) | 2019-11-15 |
| WO2014081324A1 (en) | 2014-05-30 |
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