AR079459A1 - Uso de promotores inducibles en la produccion de metionina - Google Patents
Uso de promotores inducibles en la produccion de metioninaInfo
- Publication number
- AR079459A1 AR079459A1 ARP100104626A ARP100104626A AR079459A1 AR 079459 A1 AR079459 A1 AR 079459A1 AR P100104626 A ARP100104626 A AR P100104626A AR P100104626 A ARP100104626 A AR P100104626A AR 079459 A1 AR079459 A1 AR 079459A1
- Authority
- AR
- Argentina
- Prior art keywords
- production
- methionine
- present application
- inducible promoters
- source
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente solicitud se refiere al uso de promotores inducibles en la produccion de metionina por fermentacion. La presente solicitud atane a un método para la produccion de metionina, sus precursores o derivados en un proceso de fermentacion que comprende los siguientes pasos: - el cultivo de un microorganismo modificado en un medio de cultivo adecuado que comprende una fuente de carbono, una fuente de azufre y una fuente de nitrogeno, y - la recuperacion de la metionina y/o sus derivados del medio de cultivo, en donde en dicho microorganismo modificado, la expresion de al menos un gen involucrado en la produccion de metionina está bajo el control, directo o indirecto, de un promotor inducible heterologo. La presente solicitud también se refiere a los microorganismos modificados utilizados en el método.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2009/056033 WO2011073738A1 (en) | 2009-12-14 | 2009-12-14 | Use of inducible promoters in the production of methionine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR079459A1 true AR079459A1 (es) | 2012-01-25 |
Family
ID=42558566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100104626A AR079459A1 (es) | 2009-12-14 | 2010-12-14 | Uso de promotores inducibles en la produccion de metionina |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9732364B2 (es) |
| EP (1) | EP2513322B1 (es) |
| JP (2) | JP5944323B2 (es) |
| KR (1) | KR101789215B1 (es) |
| CN (2) | CN104673852A (es) |
| AR (1) | AR079459A1 (es) |
| BR (1) | BR112012014454A2 (es) |
| ES (1) | ES2634469T3 (es) |
| MX (1) | MX2012006777A (es) |
| MY (1) | MY172455A (es) |
| PL (1) | PL2513322T3 (es) |
| WO (2) | WO2011073738A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR083468A1 (es) | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | Aumento de la disponibilidad de nadph para la produccion de metionina |
| EP2658987B1 (en) | 2010-12-30 | 2014-12-10 | Metabolic Explorer | Fermentative production of methionine hydroxy analog (mha) |
| CA2875139A1 (en) | 2012-06-18 | 2013-12-27 | Metabolic Explorer | Recombinant microorganism for the fermentative production of methionine |
| CN105658803B (zh) | 2013-08-30 | 2020-06-23 | 赢创运营有限公司 | 具有改善的甲硫氨酸合酶活性和甲硫氨酸流出的用于甲硫氨酸生产的微生物 |
| KR101641770B1 (ko) * | 2014-06-23 | 2016-07-22 | 씨제이제일제당 (주) | O-아세틸 호모세린을 생산하는 미생물 및 상기 미생물을 이용하여 o-아세틸 호모세린을 생산하는 방법 |
| JP2017525379A (ja) | 2014-09-01 | 2017-09-07 | メタボリック エクスプローラー | メチオニン排出を改善した発酵によるメチオニン産生の方法及び微生物 |
| PL3331998T3 (pl) | 2015-08-07 | 2020-12-28 | Evonik Operations Gmbh | Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka |
| RU2729012C2 (ru) | 2015-11-27 | 2020-08-03 | Эвоник Оперейшенс ГмбХ | Способ получения l-метионина |
| US10975420B2 (en) * | 2015-12-18 | 2021-04-13 | California Institute Of Technology | Thermal bioswitches and related genetic circuits, vectors, cells, compositions, methods and systems |
| EP3296404A1 (en) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modified microorganism for production of methionine |
| CN108624627B (zh) * | 2017-03-22 | 2021-07-30 | 中国科学院天津工业生物技术研究所 | 催化甲酸合成甲醛酶的制备及其应用 |
| CN109207534A (zh) * | 2018-08-29 | 2019-01-15 | 浙江工业大学 | 一种提高l-蛋氨酸产量的方法 |
| CN114401996A (zh) | 2019-07-12 | 2022-04-26 | 加州理工学院 | 模块化二聚化热开关和相关单体、二聚体、构建体、二聚复合体、载体、细胞、表面、装置组合物、方法和系统 |
| CN111996206B (zh) * | 2020-06-19 | 2023-01-31 | 清华大学 | 光控无细胞蛋白质合成方法、该方法使用的质粒以及使用该方法的产品 |
| WO2023089028A1 (en) | 2021-11-17 | 2023-05-25 | Metabolic Explorer | Microorganism and method for the improved production of valine |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998011231A1 (en) | 1996-09-10 | 1998-03-19 | The Rockefeller University | Highly regulable promoter for heterologous gene expression |
| DE19750493A1 (de) | 1997-11-14 | 1999-06-02 | Medos Medizintechnik Gmbh | Implantat zur Stabilisierung einer Fraktur und Schraube zur Verwendung in der Chirurgie |
| JP2000157267A (ja) | 1998-11-24 | 2000-06-13 | Ajinomoto Co Inc | 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法 |
| DE10239073A1 (de) | 2002-08-26 | 2004-03-11 | Basf Ag | Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien |
| DE10239308A1 (de) * | 2002-08-27 | 2004-03-11 | Basf Ag | Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien |
| FR2843973B1 (fr) | 2002-08-30 | 2006-07-07 | Agronomique Inst Nat Rech | Cassettes d'expression procaryotes regulees par le zinc |
| SI1578949T1 (sl) | 2002-10-16 | 2009-08-31 | Scripps Research Inst | Usmerjena vključitev keto aminokislin v proteine |
| US20060270013A1 (en) | 2003-02-18 | 2006-11-30 | Michel Chateau | Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways |
| EP1672060A4 (en) | 2003-09-30 | 2006-12-27 | Takara Bio Inc | POLYPEPTIDE WITH RNASE III ACTIVITY |
| DE10359668A1 (de) * | 2003-12-18 | 2005-07-14 | Basf Ag | Verfahren zur Herstellung von Methionin |
| WO2005111202A1 (en) | 2004-05-12 | 2005-11-24 | Metabolic Explorer | Recombinant enzyme with altered feedback sensitivity |
| US8178338B2 (en) | 2005-07-01 | 2012-05-15 | The Regents Of The University Of California | Inducible expression vectors and methods of use thereof |
| WO2007011845A2 (en) * | 2005-07-18 | 2007-01-25 | Basf Ag | Use of a bacillus meti gene to improve methionine production in microorganisms |
| US8389250B2 (en) * | 2006-01-04 | 2013-03-05 | Metabolic Explorer | Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine |
| WO2009043372A1 (en) | 2007-10-02 | 2009-04-09 | Metabolic Explorer | Increasing methionine yield |
-
2009
- 2009-12-14 WO PCT/IB2009/056033 patent/WO2011073738A1/en active Application Filing
-
2010
- 2010-12-13 MY MYPI2012002632A patent/MY172455A/en unknown
- 2010-12-13 PL PL10803454T patent/PL2513322T3/pl unknown
- 2010-12-13 CN CN201410643866.4A patent/CN104673852A/zh active Pending
- 2010-12-13 MX MX2012006777A patent/MX2012006777A/es unknown
- 2010-12-13 EP EP10803454.7A patent/EP2513322B1/en active Active
- 2010-12-13 US US13/515,432 patent/US9732364B2/en active Active
- 2010-12-13 WO PCT/EP2010/069473 patent/WO2011073122A1/en active Application Filing
- 2010-12-13 JP JP2012543648A patent/JP5944323B2/ja not_active Expired - Fee Related
- 2010-12-13 BR BR112012014454A patent/BR112012014454A2/pt not_active Application Discontinuation
- 2010-12-13 KR KR1020127018334A patent/KR101789215B1/ko active IP Right Grant
- 2010-12-13 CN CN201080063823.9A patent/CN102762736B/zh active Active
- 2010-12-13 ES ES10803454.7T patent/ES2634469T3/es active Active
- 2010-12-14 AR ARP100104626A patent/AR079459A1/es unknown
-
2016
- 2016-03-17 JP JP2016054051A patent/JP2016165287A/ja active Pending
-
2017
- 2017-07-11 US US15/646,940 patent/US9988655B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9988655B2 (en) | 2018-06-05 |
| KR101789215B1 (ko) | 2017-10-26 |
| CN102762736A (zh) | 2012-10-31 |
| MY172455A (en) | 2019-11-26 |
| CN102762736B (zh) | 2015-10-07 |
| JP2016165287A (ja) | 2016-09-15 |
| EP2513322A1 (en) | 2012-10-24 |
| MX2012006777A (es) | 2012-07-10 |
| ES2634469T3 (es) | 2017-09-27 |
| KR20120107992A (ko) | 2012-10-04 |
| JP5944323B2 (ja) | 2016-07-05 |
| BR112012014454A2 (pt) | 2018-08-07 |
| US9732364B2 (en) | 2017-08-15 |
| US20120252077A1 (en) | 2012-10-04 |
| CN104673852A (zh) | 2015-06-03 |
| US20170306366A1 (en) | 2017-10-26 |
| WO2011073738A1 (en) | 2011-06-23 |
| EP2513322B1 (en) | 2017-06-14 |
| WO2011073122A1 (en) | 2011-06-23 |
| JP2013513392A (ja) | 2013-04-22 |
| PL2513322T3 (pl) | 2017-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |