AR074833A1 - Agentes lipopeptidicos antibacterianos para el tratamiento de infecciones con grampositivos - Google Patents

Agentes lipopeptidicos antibacterianos para el tratamiento de infecciones con grampositivos

Info

Publication number
AR074833A1
AR074833A1 ARP090105021A ARP090105021A AR074833A1 AR 074833 A1 AR074833 A1 AR 074833A1 AR P090105021 A ARP090105021 A AR P090105021A AR P090105021 A ARP090105021 A AR P090105021A AR 074833 A1 AR074833 A1 AR 074833A1
Authority
AR
Argentina
Prior art keywords
compounds
antibacterial
lipopeptidic
grampositives
infections
Prior art date
Application number
ARP090105021A
Other languages
English (en)
Spanish (es)
Inventor
Andre Lee Pearson
Chester A Metcalf
Jing Li
Original Assignee
Cubist Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cubist Pharm Inc filed Critical Cubist Pharm Inc
Publication of AR074833A1 publication Critical patent/AR074833A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ARP090105021A 2008-12-22 2009-12-21 Agentes lipopeptidicos antibacterianos para el tratamiento de infecciones con grampositivos AR074833A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13987508P 2008-12-22 2008-12-22

Publications (1)

Publication Number Publication Date
AR074833A1 true AR074833A1 (es) 2011-02-16

Family

ID=41718893

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090105021A AR074833A1 (es) 2008-12-22 2009-12-21 Agentes lipopeptidicos antibacterianos para el tratamiento de infecciones con grampositivos

Country Status (26)

Country Link
US (3) US8507647B2 (https=)
EP (2) EP2379580B1 (https=)
JP (1) JP5670914B2 (https=)
KR (1) KR101717795B1 (https=)
CN (1) CN102325787B (https=)
AR (1) AR074833A1 (https=)
AU (1) AU2009330245C1 (https=)
BR (1) BRPI0923567A2 (https=)
CA (1) CA2747965C (https=)
CY (1) CY1114883T1 (https=)
DK (1) DK2379580T3 (https=)
ES (1) ES2442167T3 (https=)
HR (1) HRP20131170T1 (https=)
IL (1) IL213638A0 (https=)
MX (1) MX2011006803A (https=)
NZ (1) NZ594019A (https=)
PL (1) PL2379580T3 (https=)
PT (1) PT2379580E (https=)
RS (1) RS53152B (https=)
RU (1) RU2512396C2 (https=)
SG (1) SG172299A1 (https=)
SI (1) SI2379580T1 (https=)
SM (1) SMT201400037B (https=)
TW (1) TWI444198B (https=)
WO (1) WO2010075215A1 (https=)
ZA (1) ZA201104693B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2013157188A (ru) * 2011-05-26 2015-07-10 Кьюбист Фармасьютикалз, Инк. Композиции св-183,315 и относящиеся к ним способы
US10377699B2 (en) * 2013-11-06 2019-08-13 The University Of Hong Kong Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue
WO2015172047A1 (en) * 2014-05-08 2015-11-12 Merck Sharp & Dohme Corp. Cyclic peptide compounds and related methods, salts and compositions
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) * 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
ES2791319T3 (es) * 2016-04-22 2020-11-03 Astrazeneca Ab Inhibidores de MCL1 macrocíclicos para tratar el cáncer
US10098890B2 (en) 2016-10-29 2018-10-16 Cipla Limited Stable carfilzomib formulations
IT201600127655A1 (it) * 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
US10072045B1 (en) 2017-06-26 2018-09-11 Ramapo Pharmaceuticals, Inc. Antibacterial lipopeptides and methods for their preparation and use
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
USRE32455E (en) 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
EP0087953B1 (en) 1982-02-27 1988-04-27 Beecham Group Plc Antibacterial 1-normon-2-yl-heterocyclic compounds
US4396543A (en) * 1982-05-21 1983-08-02 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
USRE32310E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4399067A (en) * 1982-05-21 1983-08-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4482487A (en) * 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
USRE32311E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
US4524135A (en) * 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
US4537717A (en) * 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
SU1452484A3 (ru) 1984-10-09 1989-01-15 Эли Лилли Энд Компани (Фирма) Способ получени производных антибиотиков А-21978С, штамм стрептомицета SтRертомYсеS RoSeoSpoRUS, используемый дл получени антибиотических веществ А-21978С
ZA883887B (en) * 1987-06-10 1990-02-28 Lilly Co Eli Chromatographic purification process
US5039660A (en) 1988-03-02 1991-08-13 Endocon, Inc. Partially fused peptide pellet
ES2089133T3 (es) * 1990-06-07 1996-10-01 Lilly Co Eli Desacilasa de lipopeptidos.
AU7497594A (en) 1993-08-13 1995-03-14 Smithkline Beecham Plc Derivatives of monic acids a and c having antibacterial, antimycoplasmatical, antifungal and herbicidal activity
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE69739532D1 (de) 1996-03-08 2009-09-24 Astellas Pharma Inc Prozess für die deacylierung von zyklischen lipopeptiden.
DE19807972A1 (de) * 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
PL203689B1 (pl) 1998-09-25 2009-11-30 Cubist Pharmaceuticals Zastosowanie daptomycyny
EP1279057B1 (en) 1999-11-03 2013-03-20 The Whitaker LLC Optoelectric module for multi-fiber arrays
MXPA02006028A (es) 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
WO2001044274A1 (en) 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
CN1425025A (zh) 1999-12-15 2003-06-18 卡比斯特制药公司 作为抗菌剂的新颖的脂肽
US20060014674A1 (en) * 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
RU2348647C2 (ru) 2001-08-06 2009-03-10 Кьюбист Фармасьютикалз, Инк Новые депсипептиды и способы их получения
WO2006110185A2 (en) 2004-11-12 2006-10-19 Cubist Pharmaceuticals, Inc. Antiinfective lipopeptides

Also Published As

Publication number Publication date
US8507647B2 (en) 2013-08-13
CA2747965A1 (en) 2010-07-01
RU2011130278A (ru) 2013-01-27
RU2512396C2 (ru) 2014-04-10
EP2674437A1 (en) 2013-12-18
SG172299A1 (en) 2011-07-28
EP2379580B1 (en) 2013-10-23
RS53152B (sr) 2014-06-30
AU2009330245A1 (en) 2011-08-04
KR101717795B1 (ko) 2017-03-17
JP2012513467A (ja) 2012-06-14
WO2010075215A1 (en) 2010-07-01
TWI444198B (zh) 2014-07-11
NZ594019A (en) 2013-08-30
HK1161886A1 (en) 2012-08-10
KR20110114592A (ko) 2011-10-19
HRP20131170T1 (hr) 2014-01-03
BRPI0923567A2 (pt) 2016-09-27
SMT201400037B (it) 2014-05-07
US20140073558A1 (en) 2014-03-13
US20150337013A1 (en) 2015-11-26
JP5670914B2 (ja) 2015-02-18
CY1114883T1 (el) 2016-12-14
EP2379580A1 (en) 2011-10-26
ZA201104693B (en) 2013-01-30
CN102325787B (zh) 2014-05-28
CN102325787A (zh) 2012-01-18
PL2379580T3 (pl) 2014-05-30
MX2011006803A (es) 2011-09-06
DK2379580T3 (da) 2014-01-20
US20100184649A1 (en) 2010-07-22
SI2379580T1 (sl) 2014-02-28
PT2379580E (pt) 2014-01-20
IL213638A0 (en) 2011-07-31
ES2442167T3 (es) 2014-02-10
TW201028161A (en) 2010-08-01
AU2009330245B2 (en) 2013-05-02
CA2747965C (en) 2017-06-27
AU2009330245C1 (en) 2013-09-26

Similar Documents

Publication Publication Date Title
AR074833A1 (es) Agentes lipopeptidicos antibacterianos para el tratamiento de infecciones con grampositivos
BR112015023397A2 (pt) benzoxazois substituídos e métodos de uso dos mesmos
CO6620055A2 (es) Ciertas amino-pirimidinas, composiciones de las mismas y métodos para el uso de los mismos
CU20110052A7 (es) Compuestos orgánicos
CO6450621A2 (es) Sulfonamidas nematocidas
CU20110235A7 (es) Derivados de imidazolidin-2-ona 1,3-disustituida como inhibidores de cyp17
ECSP10010657A (es) Nuevos compuestos tricíclicos
CR20120190A (es) INHIBIDORES DE N1-PIRAZOLOESPIROCETONA ACETIL-CoA CARBOXILASA
MX343264B (es) Ciertas amino-piridazinas, composiciones de las mismas y metodos de uso de los mismos.
PE20201256A1 (es) Compuestos monobactamicos cromanos para el tratamiento de infecciones bacterianas
PE20140863A1 (es) Compuestos de benceno sustituidos con arilo o heteroarilo
PE20121695A1 (es) 5-alquinil-pirimidinas
UY32259A (es) Nuevos compuestos de hidroxiareno, preparados farmaceuticos que los contienen y aplicaciones
BR112013016595A2 (pt) inibidores de neprilisina
MX2015011436A (es) Triazolopiridinas sustituidas y metodos para usarlas.
CU20130126A7 (es) Inhibidores sustituidos de acetil-coa carboxilasa
MX2015007883A (es) Compuestos para protección de células.
CU20170084A7 (es) COMPUESTOS DE ISOXAZOL DE ÁCIDO HIDROXÁMICO COMO INHIBIDORES DE LpxC
ECSP22026478A (es) Inhibidor de diacilglicerol aciltransferasa 2
CO2018010787A2 (es) Compuesto de griseofulvina
CR20190236A (es) Compuestos terapéuticos y métodos para utilizarlos
EA201490436A1 (ru) Антибактериальные 3,4-дигидро-1н-[1,8]нафтиридиноны, замещенные гомопиперидинилом
MX2013007296A (es) Derivado novedoso de isoquinolina sustituido.
AR071762A1 (es) Derivados 5-hidroximetil-oxazolidin-2-ona para el tratamiento de enfermedades intestinales bacteriales
NI201100035A (es) Agentes antifúngicos.

Legal Events

Date Code Title Description
FB Suspension of granting procedure