AR071857A1 - Derivados de indazol sustituidos con fenilo y benzodioxinilo, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por el receptor de glucocorticoides. - Google Patents
Derivados de indazol sustituidos con fenilo y benzodioxinilo, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por el receptor de glucocorticoides.Info
- Publication number
- AR071857A1 AR071857A1 ARP090101815A ARP090101815A AR071857A1 AR 071857 A1 AR071857 A1 AR 071857A1 AR P090101815 A ARP090101815 A AR P090101815A AR P090101815 A ARP090101815 A AR P090101815A AR 071857 A1 AR071857 A1 AR 071857A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivatives
- phenyl
- benzodioxinyl
- indazol
- replaced
- Prior art date
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract
La presente se refiere a derivados de indazolilo, a composiciones farmaceuticas que contienen dichos derivados, y al uso de dichos derivados como medicamentos. Reivindicacion 1: Un compuesto caracterizado porque es de formula (1) donde A es alquilo C1-4, alcoxi C1-4, o haloalquilo C1-4; R3 es heteroarilo C5-10; W es fenilo sustituido con -C(O)NR7R8; R7 es hidrogeno o alquilo C1-4; R8 se selecciona entre hidrogeno, alquilo C1-6 (opcionalmente sustituido con uno o dos grupos seleccionados entre hidroxilo, arilo C5-10 y heteroarilo C5-10), cicloalquilo C3-7 (opcionalmente sustituido con hidroxilo), y heterociclilo C5-10 (opcionalmente sustituido con uno o dos grupos seleccionados entre hidroxilo y oxo); o una de sus sales farmaceuticamente aceptables.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US5461608P | 2008-05-20 | 2008-05-20 | |
US8031208P | 2008-07-14 | 2008-07-14 | |
US14477609P | 2009-01-15 | 2009-01-15 |
Publications (1)
Publication Number | Publication Date |
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AR071857A1 true AR071857A1 (es) | 2010-07-21 |
Family
ID=41340347
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090101815A AR071857A1 (es) | 2008-05-20 | 2009-05-20 | Derivados de indazol sustituidos con fenilo y benzodioxinilo, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por el receptor de glucocorticoides. |
ARP090101814A AR071856A1 (es) | 2008-05-20 | 2009-05-20 | Derivados de indazoles sustituidos con fenilo o piridinilo, un proceso para su preparacion, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por el receptor de glucocorticoides. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090101814A AR071856A1 (es) | 2008-05-20 | 2009-05-20 | Derivados de indazoles sustituidos con fenilo o piridinilo, un proceso para su preparacion, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por el receptor de glucocorticoides. |
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