AR071060A1 - Proceso para la preparacion de betainas - Google Patents

Proceso para la preparacion de betainas

Info

Publication number
AR071060A1
AR071060A1 ARP080104987A ARP080104987A AR071060A1 AR 071060 A1 AR071060 A1 AR 071060A1 AR P080104987 A ARP080104987 A AR P080104987A AR P080104987 A ARP080104987 A AR P080104987A AR 071060 A1 AR071060 A1 AR 071060A1
Authority
AR
Argentina
Prior art keywords
formula
betainas
preparation process
halocarboxylate
omega
Prior art date
Application number
ARP080104987A
Other languages
English (en)
Inventor
Dario Veghini
Gesa Paradies
Markus Bicker
Anton Zenklusen
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of AR071060A1 publication Critical patent/AR071060A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Reivindicacion 1: Un proceso para la produccion de una betaína de formula R3N+-QCOO- (1), donde R es alquilo C1-4 y Q es alcanodiilo C1-4, opcionalmente sustituido con hidroxi, haciendo reaccionar, en solucion acuosa, un omega-halocarboxilato de formula: X-Q-COOR' (2), donde Q es segun se lo definio anteriormente, R' es alquilo C1-4 y X es cloro, bromo o yodo, con una amina terciaria de formula: R3N (3), donde R es segun se lo definio anteriormente y una base que se selecciona entre hidroxidos alcalinos e hidroxidos alcalino térreos, caracterizado porque el omega-halocarboxilato de formula (2) se le agrega a una solucion acuosa que comprende la amina terciaria de formula (3) y la base.
ARP080104987A 2007-11-16 2008-11-14 Proceso para la preparacion de betainas AR071060A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07022273 2007-11-16

Publications (1)

Publication Number Publication Date
AR071060A1 true AR071060A1 (es) 2010-05-26

Family

ID=39094022

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080104987A AR071060A1 (es) 2007-11-16 2008-11-14 Proceso para la preparacion de betainas

Country Status (11)

Country Link
US (1) US8168823B2 (es)
EP (1) EP2231587B1 (es)
JP (1) JP5155406B2 (es)
KR (1) KR101132589B1 (es)
CN (1) CN101861298B (es)
AR (1) AR071060A1 (es)
AT (1) ATE523483T1 (es)
ES (1) ES2372723T3 (es)
SA (1) SA08290725B1 (es)
TW (1) TWI400223B (es)
WO (1) WO2009062731A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2216088A1 (en) * 2009-02-04 2010-08-11 Lonza Ltd. Recovery of product losses from ED waste streams
FR2957919B1 (fr) * 2010-03-23 2012-06-01 Rhodia Operations Procede continu de fabrication de solutions aqueuses de betaine
EP2409965A1 (en) * 2010-07-21 2012-01-25 Lonza Ltd. A process for the production of carnitine by cycloaddition
US9394238B2 (en) 2010-07-21 2016-07-19 Lonza Ltd. Process for the production of carnitine from β-lactones
EP2551350A1 (en) 2011-07-27 2013-01-30 Lonza Ltd Process for producing L-carnitine from ß-lactones employing lipases
CN103012177B (zh) * 2012-12-17 2015-04-08 苏州浩波科技股份有限公司 左旋肉碱的制备方法
CN104030934B (zh) * 2014-07-04 2016-06-15 东北制药集团股份有限公司 一种左卡尼汀化合物的制备方法
CN106588680B (zh) * 2016-11-07 2018-04-24 杭州海尔希畜牧科技有限公司 一种制备十二烷基甜菜碱的方法
CN111592466B (zh) * 2020-06-05 2022-08-19 复旦大学 一种左卡尼汀的微反应连续流合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800502A (en) * 1953-11-23 1957-07-23 Int Minerals & Chem Corp Synthesis of betaine hydrate
JPS60161953A (ja) * 1984-01-31 1985-08-23 Denki Kagaku Kogyo Kk カルニチン類の製造法
DE3419724A1 (de) * 1984-05-26 1985-11-28 Basf Ag, 6700 Ludwigshafen Verfahren zur gewinnung waessriger carnitin- bzw. carnitinamid-loesungen
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
IT1190358B (it) * 1985-05-24 1988-02-16 Sclavo Spa Procedimento per la preparazione di l-carnitina
JPH0678277B2 (ja) * 1988-02-19 1994-10-05 高砂香料工業株式会社 光学活性アルコールおよびその誘導体の製造方法
US5545667A (en) * 1991-04-26 1996-08-13 The Clorox Company Methods for treating neoplasms with betaines
US5696287A (en) * 1996-07-22 1997-12-09 Ducoa, L. P. Process for making aqueous betaine solutions
IT1303757B1 (it) * 1998-11-16 2001-02-23 Sigma Tau Ind Farmaceuti Processo industriale per la produzione di l-carnitina.
JP5214249B2 (ja) * 2006-11-09 2013-06-19 三菱レイヨン株式会社 ベタインの製造方法

Also Published As

Publication number Publication date
ATE523483T1 (de) 2011-09-15
JP2011503132A (ja) 2011-01-27
TWI400223B (zh) 2013-07-01
KR20100090285A (ko) 2010-08-13
EP2231587A1 (en) 2010-09-29
US8168823B2 (en) 2012-05-01
EP2231587B1 (en) 2011-09-07
WO2009062731A1 (en) 2009-05-22
ES2372723T3 (es) 2012-01-25
US20100267986A1 (en) 2010-10-21
TW200922912A (en) 2009-06-01
CN101861298B (zh) 2014-10-29
CN101861298A (zh) 2010-10-13
JP5155406B2 (ja) 2013-03-06
SA08290725B1 (ar) 2011-04-05
KR101132589B1 (ko) 2012-04-06

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed, e.g., due to non-payment of fee