AR069862A1 - Inhibidores de pi3 quinasa - Google Patents
Inhibidores de pi3 quinasaInfo
- Publication number
- AR069862A1 AR069862A1 ARP080105607A ARP080105607A AR069862A1 AR 069862 A1 AR069862 A1 AR 069862A1 AR P080105607 A ARP080105607 A AR P080105607A AR P080105607 A ARP080105607 A AR P080105607A AR 069862 A1 AR069862 A1 AR 069862A1
- Authority
- AR
- Argentina
- Prior art keywords
- substituted
- independently
- alkyl
- alkynyl
- cycloalkyl
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 4
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 4
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 4
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 4
- 125000001072 heteroaryl group Chemical group 0.000 abstract 4
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US843007P | 2007-12-19 | 2007-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069862A1 true AR069862A1 (es) | 2010-02-24 |
Family
ID=40364443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080105607A AR069862A1 (es) | 2007-12-19 | 2008-12-19 | Inhibidores de pi3 quinasa |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7820665B2 (enExample) |
| EP (1) | EP2231661A1 (enExample) |
| JP (1) | JP5520831B2 (enExample) |
| AR (1) | AR069862A1 (enExample) |
| AU (1) | AU2008343813B2 (enExample) |
| CA (1) | CA2710194C (enExample) |
| CL (1) | CL2008003798A1 (enExample) |
| PE (1) | PE20091268A1 (enExample) |
| TW (1) | TW200940544A (enExample) |
| WO (1) | WO2009085230A1 (enExample) |
Families Citing this family (105)
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| KR20100044852A (ko) * | 2007-08-17 | 2010-04-30 | 이카겐, 인코포레이티드 | 칼륨 채널 조절제로서의 헤테로사이클 |
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| EP2277881A4 (en) * | 2008-04-18 | 2011-09-07 | Shionogi & Co | HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON P13K |
| AR071523A1 (es) * | 2008-04-30 | 2010-06-23 | Merck Serono Sa | Compuestos biciclicos fusionados, un proceso para su preparacion, el compuesto para ser utilizado como medicamento en el tratamiento y profilaxis de enfermedades, una composicion farmaceutica y un conjunto que comprende paquetes separados del compuesto y de un ingrediente activo del medicamento |
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-
2008
- 2008-12-18 CA CA2710194A patent/CA2710194C/en not_active Expired - Fee Related
- 2008-12-18 CL CL2008003798A patent/CL2008003798A1/es unknown
- 2008-12-18 WO PCT/US2008/013940 patent/WO2009085230A1/en not_active Ceased
- 2008-12-18 JP JP2010539504A patent/JP5520831B2/ja not_active Expired - Fee Related
- 2008-12-18 US US12/317,166 patent/US7820665B2/en active Active
- 2008-12-18 EP EP08867948A patent/EP2231661A1/en not_active Withdrawn
- 2008-12-18 AU AU2008343813A patent/AU2008343813B2/en not_active Ceased
- 2008-12-18 PE PE2008002118A patent/PE20091268A1/es not_active Application Discontinuation
- 2008-12-19 AR ARP080105607A patent/AR069862A1/es not_active Application Discontinuation
- 2008-12-19 TW TW097149904A patent/TW200940544A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011507854A (ja) | 2011-03-10 |
| PE20091268A1 (es) | 2009-09-19 |
| US7820665B2 (en) | 2010-10-26 |
| AU2008343813A1 (en) | 2009-07-09 |
| CA2710194C (en) | 2014-04-22 |
| JP5520831B2 (ja) | 2014-06-11 |
| EP2231661A1 (en) | 2010-09-29 |
| TW200940544A (en) | 2009-10-01 |
| CA2710194A1 (en) | 2009-07-09 |
| US20090163489A1 (en) | 2009-06-25 |
| AU2008343813B2 (en) | 2012-04-12 |
| WO2009085230A1 (en) | 2009-07-09 |
| CL2008003798A1 (es) | 2009-10-09 |
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