SG11202101886VA - Processes for preparing a mdm2 inhibitor - Google Patents
Processes for preparing a mdm2 inhibitorInfo
- Publication number
- SG11202101886VA SG11202101886VA SG11202101886VA SG11202101886VA SG11202101886VA SG 11202101886V A SG11202101886V A SG 11202101886VA SG 11202101886V A SG11202101886V A SG 11202101886VA SG 11202101886V A SG11202101886V A SG 11202101886VA SG 11202101886V A SG11202101886V A SG 11202101886VA
- Authority
- SG
- Singapore
- Prior art keywords
- preparing
- processes
- mdm2 inhibitor
- mdm2
- inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/12—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862725574P | 2018-08-31 | 2018-08-31 | |
| PCT/US2019/049087 WO2020047424A1 (en) | 2018-08-31 | 2019-08-30 | Processes for preparing a mdm2 inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202101886VA true SG11202101886VA (en) | 2021-03-30 |
Family
ID=69643829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202101886VA SG11202101886VA (en) | 2018-08-31 | 2019-08-30 | Processes for preparing a mdm2 inhibitor |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11753386B2 (en) |
| EP (1) | EP3843733A4 (en) |
| JP (2) | JP7408635B2 (en) |
| KR (1) | KR20210052497A (en) |
| AU (1) | AU2019327555A1 (en) |
| BR (1) | BR112021003839A2 (en) |
| CA (1) | CA3110525A1 (en) |
| EA (1) | EA202190632A1 (en) |
| IL (1) | IL281040A (en) |
| MX (1) | MX2021002397A (en) |
| SG (1) | SG11202101886VA (en) |
| WO (1) | WO2020047424A1 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2998B1 (en) * | 2010-06-04 | 2016-09-05 | Amgen Inc | Piperidinone derivatives as mdm2 inhibitors for the treatment of cancer |
| JOP20200296A1 (en) | 2013-06-10 | 2017-06-16 | Amgen Inc | Processes of Making and Crystalline Forms of a MDM2 Inhibitor |
-
2019
- 2019-08-30 SG SG11202101886VA patent/SG11202101886VA/en unknown
- 2019-08-30 EA EA202190632A patent/EA202190632A1/en unknown
- 2019-08-30 AU AU2019327555A patent/AU2019327555A1/en active Pending
- 2019-08-30 CA CA3110525A patent/CA3110525A1/en active Pending
- 2019-08-30 MX MX2021002397A patent/MX2021002397A/en unknown
- 2019-08-30 US US17/272,031 patent/US11753386B2/en active Active
- 2019-08-30 EP EP19854904.0A patent/EP3843733A4/en active Pending
- 2019-08-30 JP JP2021510396A patent/JP7408635B2/en active Active
- 2019-08-30 BR BR112021003839-6A patent/BR112021003839A2/en unknown
- 2019-08-30 KR KR1020217009113A patent/KR20210052497A/en active Search and Examination
- 2019-08-30 WO PCT/US2019/049087 patent/WO2020047424A1/en unknown
-
2021
- 2021-02-23 IL IL281040A patent/IL281040A/en unknown
-
2023
- 2023-12-19 JP JP2023213604A patent/JP2024037957A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210347743A1 (en) | 2021-11-11 |
| IL281040A (en) | 2021-04-29 |
| CN112912080A (en) | 2021-06-04 |
| US11753386B2 (en) | 2023-09-12 |
| KR20210052497A (en) | 2021-05-10 |
| EA202190632A1 (en) | 2021-06-16 |
| BR112021003839A2 (en) | 2021-07-27 |
| AU2019327555A1 (en) | 2021-03-18 |
| JP7408635B2 (en) | 2024-01-05 |
| EP3843733A1 (en) | 2021-07-07 |
| EP3843733A4 (en) | 2022-08-24 |
| JP2024037957A (en) | 2024-03-19 |
| CA3110525A1 (en) | 2020-03-05 |
| JP2021535130A (en) | 2021-12-16 |
| WO2020047424A9 (en) | 2020-04-30 |
| WO2020047424A1 (en) | 2020-03-05 |
| MX2021002397A (en) | 2021-04-29 |
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