AR067701A1 - Metodos y composiciones utiles para la preparacion de inhibidores del contransportador de sodio y glucosa 2 - Google Patents

Metodos y composiciones utiles para la preparacion de inhibidores del contransportador de sodio y glucosa 2

Info

Publication number
AR067701A1
AR067701A1 ARP080103246A ARP080103246A AR067701A1 AR 067701 A1 AR067701 A1 AR 067701A1 AR P080103246 A ARP080103246 A AR P080103246A AR P080103246 A ARP080103246 A AR P080103246A AR 067701 A1 AR067701 A1 AR 067701A1
Authority
AR
Argentina
Prior art keywords
sodium
inhibitors
glucose
contractor
compositions
Prior art date
Application number
ARP080103246A
Other languages
English (en)
Inventor
Nicole Cathleen Goodwin
Bryce Alden Harrison
Shinya Limura
Ross Mabon
Jie Yan
Matthew Mangzhu Zhang
Wenxue Wu
Qiuling Song
Haiming Zhang
Original Assignee
Lexicon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexicon Pharmaceuticals Inc filed Critical Lexicon Pharmaceuticals Inc
Publication of AR067701A1 publication Critical patent/AR067701A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Métodos para sintetizar inhibidores del cotransportador de sodio y glucosa 2 Compuestos utiles para tal fin. Reivindicacion 2: El cocristal de la reivindicacion 1 caracterizado porque el aminoácido aceptable para su uso farmacéutico es L-fenilalanina, L-fenilglicina, o L-arginina.
ARP080103246A 2007-07-26 2008-07-25 Metodos y composiciones utiles para la preparacion de inhibidores del contransportador de sodio y glucosa 2 AR067701A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95212207P 2007-07-26 2007-07-26

Publications (1)

Publication Number Publication Date
AR067701A1 true AR067701A1 (es) 2009-10-21

Family

ID=39877996

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP080103246A AR067701A1 (es) 2007-07-26 2008-07-25 Metodos y composiciones utiles para la preparacion de inhibidores del contransportador de sodio y glucosa 2
ARP180102213 AR112669A2 (es) 2007-07-26 2018-08-03 Compuestos inhibidores del cotransportador de sodio y glucosa 2 y compuestos útiles para su preparación

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP180102213 AR112669A2 (es) 2007-07-26 2018-08-03 Compuestos inhibidores del cotransportador de sodio y glucosa 2 y compuestos útiles para su preparación

Country Status (25)

Country Link
US (2) US8026347B2 (es)
EP (1) EP2183263B1 (es)
JP (2) JP5653213B2 (es)
KR (1) KR101663324B1 (es)
CN (1) CN101801989B (es)
AR (2) AR067701A1 (es)
AT (1) ATE530558T1 (es)
AU (1) AU2008279424B2 (es)
BR (1) BRPI0813840A2 (es)
CA (1) CA2694029C (es)
CL (1) CL2008002169A1 (es)
CO (1) CO6260141A2 (es)
DK (1) DK2183263T3 (es)
EA (1) EA017411B1 (es)
EC (1) ECSP109987A (es)
ES (1) ES2375800T3 (es)
HK (1) HK1143982A1 (es)
IL (1) IL203209A (es)
NZ (1) NZ582536A (es)
PL (1) PL2183263T3 (es)
PT (1) PT2183263E (es)
TW (2) TWI419886B (es)
UA (1) UA107175C2 (es)
WO (1) WO2009014970A1 (es)
ZA (1) ZA201000219B (es)

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CN108675976B (zh) * 2018-05-14 2020-07-14 浙江宏元药业股份有限公司 一种6-卤代葡萄糖碳苷及其制备方法和应用
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CN110818722B (zh) * 2018-08-14 2022-12-02 苏州鹏旭医药科技有限公司 三种化合物及其制备方法和在合成索格列净中的用途
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Also Published As

Publication number Publication date
ECSP109987A (es) 2010-03-31
JP2010534661A (ja) 2010-11-11
KR20100040869A (ko) 2010-04-21
TW201350473A (zh) 2013-12-16
BRPI0813840A2 (pt) 2017-06-06
JP2014001230A (ja) 2014-01-09
PT2183263E (pt) 2012-01-11
ATE530558T1 (de) 2011-11-15
EP2183263B1 (en) 2011-10-26
EP2183263A1 (en) 2010-05-12
CN101801989A (zh) 2010-08-11
CA2694029C (en) 2016-10-04
HK1143982A1 (zh) 2011-01-21
DK2183263T3 (da) 2012-01-30
US8026347B2 (en) 2011-09-27
NZ582536A (en) 2012-01-12
TWI419886B (zh) 2013-12-21
US8293878B2 (en) 2012-10-23
AU2008279424B2 (en) 2013-06-13
CN101801989B (zh) 2015-11-25
CL2008002169A1 (es) 2009-03-20
TWI506024B (zh) 2015-11-01
ES2375800T3 (es) 2012-03-06
AU2008279424A1 (en) 2009-01-29
JP5653213B2 (ja) 2015-01-14
WO2009014970A1 (en) 2009-01-29
PL2183263T3 (pl) 2012-03-30
CA2694029A1 (en) 2009-01-29
ZA201000219B (en) 2011-03-30
CO6260141A2 (es) 2011-03-22
KR101663324B1 (ko) 2016-10-06
AR112669A2 (es) 2019-11-27
TW200914434A (en) 2009-04-01
IL203209A (en) 2014-02-27
US20090030198A1 (en) 2009-01-29
JP5764174B2 (ja) 2015-08-12
UA107175C2 (uk) 2014-12-10
EA201070186A1 (ru) 2010-08-30
US20120095197A1 (en) 2012-04-19
EA017411B1 (ru) 2012-12-28

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