AR062856A1 - Compuestos derivados de aziridina utilizados en marcacion radioactiva por fluoracion del compuesto - Google Patents
Compuestos derivados de aziridina utilizados en marcacion radioactiva por fluoracion del compuestoInfo
- Publication number
- AR062856A1 AR062856A1 ARP070104087A ARP070104087A AR062856A1 AR 062856 A1 AR062856 A1 AR 062856A1 AR P070104087 A ARP070104087 A AR P070104087A AR P070104087 A ARP070104087 A AR P070104087A AR 062856 A1 AR062856 A1 AR 062856A1
- Authority
- AR
- Argentina
- Prior art keywords
- fluoration
- composite
- compounds derived
- aziridine
- radioactive marking
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C07D203/24—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Compuestos adecuados para ser marcados o ya marcados radioactivamente con 18F, métodos para preparar tales compuestos y uso de los mismos para diagnostico para imágenes. Un compuesto caracterizado porque comprende un anillo de aziridina apropiadamente activado con fines de marcacion, en el cual un radical agente de direccionamiento, está unido, ya sea directamente o a través de un conector apropiado, al anillo de aziridina o a un anillo carbocíclico o heterocíclico de cinco miembros que está fusionado al anillo de aziridina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07090001A EP1944288A1 (en) | 2007-01-09 | 2007-01-09 | Radiolabelling via fluorination of aziridines |
EP07090079A EP1985624A3 (en) | 2007-04-23 | 2007-04-23 | Single step method of radiofluorination of biologically active compounds or biomolecules |
Publications (1)
Publication Number | Publication Date |
---|---|
AR062856A1 true AR062856A1 (es) | 2008-12-10 |
Family
ID=38941926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070104087A AR062856A1 (es) | 2007-01-09 | 2007-09-14 | Compuestos derivados de aziridina utilizados en marcacion radioactiva por fluoracion del compuesto |
Country Status (24)
Country | Link |
---|---|
US (1) | US20090022664A1 (es) |
EP (1) | EP2099747A1 (es) |
JP (1) | JP2010522140A (es) |
KR (1) | KR20090096716A (es) |
AR (1) | AR062856A1 (es) |
AU (1) | AU2007343454A1 (es) |
BR (1) | BRPI0720884A2 (es) |
CA (1) | CA2674408A1 (es) |
CL (1) | CL2007002673A1 (es) |
CO (1) | CO6220852A2 (es) |
CR (1) | CR10917A (es) |
DO (1) | DOP2009000173A (es) |
EC (1) | ECSP099505A (es) |
MA (1) | MA31175B1 (es) |
MX (1) | MX2009007395A (es) |
NO (1) | NO20092813L (es) |
PA (1) | PA8747801A1 (es) |
PE (1) | PE20081661A1 (es) |
RU (1) | RU2009130455A (es) |
SV (1) | SV2009003328A (es) |
TN (1) | TN2009000233A1 (es) |
TW (1) | TW200829275A (es) |
UY (1) | UY30594A1 (es) |
WO (1) | WO2008083729A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8784774B2 (en) | 2011-09-16 | 2014-07-22 | General Electric Company | Labeled molecular imaging agents and methods of use |
US9468692B2 (en) | 2014-01-23 | 2016-10-18 | General Electric Company | Labeled molecular imaging agents and methods of use |
US9468693B2 (en) | 2014-01-23 | 2016-10-18 | General Electric Company | Labeled molecular imaging agents and methods of use |
NL2014828B1 (en) * | 2015-05-20 | 2017-01-31 | Out And Out Chemistry S P R L | Method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, a device and cassette for performing this method. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3954994A (en) * | 1968-10-03 | 1976-05-04 | Pfizer Inc. | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents |
JPS5810380B2 (ja) * | 1975-01-31 | 1983-02-25 | 三共株式会社 | ペプチドノ セイホウ |
US6015790A (en) * | 1997-10-06 | 2000-01-18 | Basf Aktiengesellschaft | Methods and compositions for treating rheumatoid arthritis |
WO2001007414A1 (en) * | 1999-07-21 | 2001-02-01 | The Trustees Of The University Of Pennsylvania | Preparation of compounds useful for the detection of hypoxia |
SE9903998D0 (sv) * | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
US6894057B2 (en) * | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
JP2006503008A (ja) * | 2002-08-13 | 2006-01-26 | ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー | マトリクスメタロプロテイナーゼ阻害物質としての4−ヒドロキシキノリン誘導体 |
GB0222909D0 (en) * | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
US6875784B2 (en) * | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
CN1212307C (zh) * | 2003-07-23 | 2005-07-27 | 中国科学院上海有机化学研究所 | 一种合成β-氟胺化合物的方法 |
AU2005289881A1 (en) * | 2004-09-23 | 2006-04-06 | Amgen Inc. | Substituted sulfonamidopropionamides and methods of use |
JP2008535839A (ja) * | 2005-04-07 | 2008-09-04 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤 |
-
2007
- 2007-09-07 KR KR1020097014304A patent/KR20090096716A/ko not_active Application Discontinuation
- 2007-09-07 BR BRPI0720884-7A patent/BRPI0720884A2/pt not_active IP Right Cessation
- 2007-09-07 AU AU2007343454A patent/AU2007343454A1/en not_active Abandoned
- 2007-09-07 MX MX2009007395A patent/MX2009007395A/es unknown
- 2007-09-07 WO PCT/EP2007/007968 patent/WO2008083729A1/en active Application Filing
- 2007-09-07 US US11/851,786 patent/US20090022664A1/en not_active Abandoned
- 2007-09-07 RU RU2009130455/04A patent/RU2009130455A/ru not_active Application Discontinuation
- 2007-09-07 CA CA002674408A patent/CA2674408A1/en not_active Abandoned
- 2007-09-07 JP JP2009545069A patent/JP2010522140A/ja active Pending
- 2007-09-07 EP EP07802294A patent/EP2099747A1/en not_active Withdrawn
- 2007-09-10 TW TW096133836A patent/TW200829275A/zh unknown
- 2007-09-14 PA PA20078747801A patent/PA8747801A1/es unknown
- 2007-09-14 PE PE2007001247A patent/PE20081661A1/es not_active Application Discontinuation
- 2007-09-14 AR ARP070104087A patent/AR062856A1/es unknown
- 2007-09-14 CL CL200702673A patent/CL2007002673A1/es unknown
- 2007-09-14 UY UY30594A patent/UY30594A1/es not_active Application Discontinuation
-
2009
- 2009-06-08 TN TNP2009000233A patent/TN2009000233A1/fr unknown
- 2009-07-08 DO DO2009000173A patent/DOP2009000173A/es unknown
- 2009-07-09 CR CR10917A patent/CR10917A/es unknown
- 2009-07-09 CO CO09071219A patent/CO6220852A2/es not_active Application Discontinuation
- 2009-07-09 SV SV2009003328A patent/SV2009003328A/es not_active Application Discontinuation
- 2009-07-09 EC EC2009009505A patent/ECSP099505A/es unknown
- 2009-08-06 MA MA32154A patent/MA31175B1/fr unknown
- 2009-08-07 NO NO20092813A patent/NO20092813L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2007343454A1 (en) | 2008-07-17 |
BRPI0720884A2 (pt) | 2014-03-25 |
CO6220852A2 (es) | 2010-11-19 |
WO2008083729A1 (en) | 2008-07-17 |
EP2099747A1 (en) | 2009-09-16 |
JP2010522140A (ja) | 2010-07-01 |
US20090022664A1 (en) | 2009-01-22 |
UY30594A1 (es) | 2008-09-02 |
PA8747801A1 (es) | 2009-08-26 |
TN2009000233A1 (en) | 2010-10-18 |
MX2009007395A (es) | 2009-07-17 |
PE20081661A1 (es) | 2009-01-18 |
ECSP099505A (es) | 2009-08-28 |
CA2674408A1 (en) | 2008-07-17 |
CR10917A (es) | 2009-08-27 |
TW200829275A (en) | 2008-07-16 |
CL2007002673A1 (es) | 2008-07-18 |
RU2009130455A (ru) | 2011-02-20 |
KR20090096716A (ko) | 2009-09-14 |
DOP2009000173A (es) | 2010-10-31 |
MA31175B1 (fr) | 2010-02-01 |
NO20092813L (no) | 2009-09-22 |
SV2009003328A (es) | 2009-12-14 |
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Legal Events
Date | Code | Title | Description |
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FB | Suspension of granting procedure |