AR060471A1 - Organismos clostridium recombinantes atenuados y vacuna - Google Patents
Organismos clostridium recombinantes atenuados y vacunaInfo
- Publication number
- AR060471A1 AR060471A1 ARP070101608A ARP070101608A AR060471A1 AR 060471 A1 AR060471 A1 AR 060471A1 AR P070101608 A ARP070101608 A AR P070101608A AR P070101608 A ARP070101608 A AR P070101608A AR 060471 A1 AR060471 A1 AR 060471A1
- Authority
- AR
- Argentina
- Prior art keywords
- organisms
- recombinants
- vaccine
- damaged
- attenuated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Organismos Clostridium perfringens atenuados, que expresan una toxina alfa sustancialmente no toxica. La toxina alfa expresada es una muteína de delecion a la que, en relacion con la toxina alfa de la toxina alfa madura de la cepa 13 de Clostridium perfringens, le faltan por lo menos 9 residuos de aminoácidos consecutivos, que incluyen His68. Además organismos atenuados que codifican las muteínas, y también, el uso de dichos organismos atenuados como vacunas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79255306P | 2006-04-17 | 2006-04-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR060471A1 true AR060471A1 (es) | 2008-06-18 |
Family
ID=38625523
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070101608A AR060471A1 (es) | 2006-04-17 | 2007-04-16 | Organismos clostridium recombinantes atenuados y vacuna |
ARP110100176A AR079941A2 (es) | 2006-04-17 | 2011-01-19 | Organismos clostridium atenuados recombinados y vacuna |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP110100176A AR079941A2 (es) | 2006-04-17 | 2011-01-19 | Organismos clostridium atenuados recombinados y vacuna |
Country Status (24)
Country | Link |
---|---|
US (3) | US7732187B2 (es) |
EP (2) | EP2368571A1 (es) |
JP (2) | JP5551933B2 (es) |
KR (1) | KR20080110908A (es) |
CN (1) | CN101489584B (es) |
AR (2) | AR060471A1 (es) |
AU (1) | AU2007240949B2 (es) |
BR (1) | BRPI0711572A2 (es) |
CA (1) | CA2649426C (es) |
CO (1) | CO6140037A2 (es) |
EC (1) | ECSP088827A (es) |
ES (1) | ES2401810T3 (es) |
HK (1) | HK1125315A1 (es) |
IL (1) | IL194714A (es) |
MX (1) | MX2008013451A (es) |
NO (1) | NO20084810L (es) |
NZ (1) | NZ571970A (es) |
PE (1) | PE20080167A1 (es) |
PL (1) | PL2007420T3 (es) |
RU (2) | RU2593945C2 (es) |
TW (1) | TWI338045B (es) |
UA (2) | UA109105C2 (es) |
WO (1) | WO2007123850A2 (es) |
ZA (1) | ZA200808872B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070077256A1 (en) | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
US20060083750A1 (en) * | 1999-11-19 | 2006-04-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis |
MX343525B (es) * | 2008-04-29 | 2016-11-09 | Immunexcite Inc | Composiciones inmunomoduladoras y metodos de uso de las mismas. |
AU2011299285B2 (en) * | 2010-09-10 | 2017-01-05 | Ntcd, Llc | Environmental Clostridial bacteriotherapy and related formulations and methods of manufacture and use |
EP2734229B1 (en) | 2011-07-22 | 2019-01-02 | Novadigm Therapeutics, Inc. | Methods and copositions for vaccinating against staphylococcus aureus |
EP2820044A1 (en) * | 2012-03-02 | 2015-01-07 | Regeneron Pharmaceuticals, Inc. | Human antibodies to clostridium difficile toxins |
BR112015008775A2 (pt) | 2012-10-26 | 2017-07-04 | Intervet Int Bv | sorotipo c1 do sorogrupo de salmonella enterica, uso de um sorotipo c1 do sorogrupo de salmonella enterica, e, vacina para administração a aves |
CA2906771A1 (en) | 2013-03-15 | 2014-09-18 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for treating fungal and bacterial pathogens |
WO2017155949A1 (en) | 2016-03-09 | 2017-09-14 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Methods and kits for use in preventing and treating vulvovaginal candidiasis |
CN109602898B (zh) * | 2018-12-28 | 2022-02-22 | 江苏省农业科学院 | 一种产气荚膜梭菌α毒素基因工程疫苗及其制备方法 |
US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
CN114621963A (zh) * | 2022-03-11 | 2022-06-14 | 牧原食品股份有限公司 | 一种猪魏氏梭菌a型的亚单位疫苗及其制备 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1483042A (en) * | 1974-07-29 | 1977-08-17 | Lapointe J | Anti-tumour product of bacterial origin |
SU627611A1 (ru) * | 1977-09-30 | 1980-02-05 | В.П. Землякова | Вакцинный препарат в.п. земл ковой против клостридиозов животных и птиц |
GB9115332D0 (en) * | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
MX9302964A (es) * | 1992-05-20 | 1995-01-31 | Secr Defence | Vacunas de clostridium perfringens. |
GB9605222D0 (en) | 1996-03-12 | 1996-05-15 | Secr Defence | Clostridium perfringens epsilon toxin vaccines |
ATE346931T1 (de) * | 1997-06-20 | 2006-12-15 | Intervet Int Bv | Clostridium perfringens impfstoff |
RU2129441C1 (ru) * | 1997-12-10 | 1999-04-27 | Пирожков Михаил Константинович | Вакцина, ассоциированная против анаэробной энтеротоксемии и эшерихиоза поросят |
US6399074B1 (en) * | 1998-07-24 | 2002-06-04 | Megan Health, Inc. | Live attenuated salmonella vaccines to control avian pathogens |
AUPQ899700A0 (en) * | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
KR20050098837A (ko) * | 2002-12-09 | 2005-10-12 | 유니버시티 오브 조지아 리서치 파운데이션 인코퍼레이티드 | 구포자충 백신 및 이를 사용하고 제조하는 방법 |
BRPI0416376A (pt) * | 2003-11-10 | 2007-03-06 | Uab Research Foundation | composições para a redução da colonização bacteriana e da invasão do snc e métodos de uso destes |
MY149604A (en) * | 2005-04-18 | 2013-09-13 | Schering Plough Ltd | C.perfringens alpha toxoid vaccine |
-
2007
- 2007-04-12 ES ES07755417T patent/ES2401810T3/es active Active
- 2007-04-12 EP EP11157448A patent/EP2368571A1/en not_active Withdrawn
- 2007-04-12 EP EP07755417A patent/EP2007420B1/en active Active
- 2007-04-12 AU AU2007240949A patent/AU2007240949B2/en not_active Ceased
- 2007-04-12 JP JP2009506518A patent/JP5551933B2/ja not_active Expired - Fee Related
- 2007-04-12 NZ NZ571970A patent/NZ571970A/en not_active IP Right Cessation
- 2007-04-12 KR KR1020087027923A patent/KR20080110908A/ko not_active Application Discontinuation
- 2007-04-12 BR BRPI0711572-5A patent/BRPI0711572A2/pt not_active IP Right Cessation
- 2007-04-12 PL PL07755417T patent/PL2007420T3/pl unknown
- 2007-04-12 CN CN2007800225963A patent/CN101489584B/zh not_active Expired - Fee Related
- 2007-04-12 RU RU2011147308/10A patent/RU2593945C2/ru active
- 2007-04-12 RU RU2008144913/10A patent/RU2445364C2/ru active
- 2007-04-12 US US11/734,454 patent/US7732187B2/en active Active
- 2007-04-12 WO PCT/US2007/009135 patent/WO2007123850A2/en active Application Filing
- 2007-04-12 CA CA2649426A patent/CA2649426C/en not_active Expired - Fee Related
- 2007-04-12 MX MX2008013451A patent/MX2008013451A/es active IP Right Grant
- 2007-04-12 UA UAA201106572A patent/UA109105C2/ru unknown
- 2007-04-16 AR ARP070101608A patent/AR060471A1/es active IP Right Grant
- 2007-04-16 PE PE2007000464A patent/PE20080167A1/es not_active Application Discontinuation
- 2007-04-17 TW TW096113489A patent/TWI338045B/zh not_active IP Right Cessation
- 2007-12-04 UA UAA200813301A patent/UA95951C2/ru unknown
-
2008
- 2008-10-12 IL IL194714A patent/IL194714A/en not_active IP Right Cessation
- 2008-10-16 ZA ZA200808872A patent/ZA200808872B/xx unknown
- 2008-10-16 EC EC2008008827A patent/ECSP088827A/es unknown
- 2008-10-17 CO CO08110815A patent/CO6140037A2/es unknown
- 2008-11-14 NO NO20084810A patent/NO20084810L/no not_active Application Discontinuation
-
2009
- 2009-05-08 HK HK09104268.8A patent/HK1125315A1/xx not_active IP Right Cessation
- 2009-12-17 US US12/640,645 patent/US7807456B2/en active Active
-
2010
- 2010-08-27 US US12/869,813 patent/US7972604B2/en active Active
-
2011
- 2011-01-19 AR ARP110100176A patent/AR079941A2/es not_active Application Discontinuation
-
2013
- 2013-09-17 JP JP2013191854A patent/JP2013255518A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration |