AR055365A1 - Benzoato de n{2-[((2s)-3-{[1-(4-clorobencil)piperidin-4il]amino}-2-hidroxi-2-metilpropil)oxi]-4-hidroxifenil}acetamida - Google Patents

Benzoato de n{2-[((2s)-3-{[1-(4-clorobencil)piperidin-4il]amino}-2-hidroxi-2-metilpropil)oxi]-4-hidroxifenil}acetamida

Info

Publication number
AR055365A1
AR055365A1 ARP060103358A ARP060103358A AR055365A1 AR 055365 A1 AR055365 A1 AR 055365A1 AR P060103358 A ARP060103358 A AR P060103358A AR P060103358 A ARP060103358 A AR P060103358A AR 055365 A1 AR055365 A1 AR 055365A1
Authority
AR
Argentina
Prior art keywords
piperidin
amino
methylpropil
chlorobencil
hydroxi
Prior art date
Application number
ARP060103358A
Other languages
English (en)
Inventor
Julien Giovannini
Bo-Goeran Josefsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37708911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR055365(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR055365A1 publication Critical patent/AR055365A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Benzoato de N-{2-[((2S)-3-{[1-(4-clorobencil)piperidin-4-il]amino}-2-hidroxi-2-metilpropil)oxi]-4-hidrofenil}acetamida, o un solvato del mismo, composiciones farmacéuticas que contienen la sal o el solvato y uso de la sal o el solvato en terapias para la enfermedad pulmonar obstructiva cronica, asma.
ARP060103358A 2005-08-02 2006-08-02 Benzoato de n{2-[((2s)-3-{[1-(4-clorobencil)piperidin-4il]amino}-2-hidroxi-2-metilpropil)oxi]-4-hidroxifenil}acetamida AR055365A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0501768 2005-08-02

Publications (1)

Publication Number Publication Date
AR055365A1 true AR055365A1 (es) 2007-08-22

Family

ID=37708911

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060103358A AR055365A1 (es) 2005-08-02 2006-08-02 Benzoato de n{2-[((2s)-3-{[1-(4-clorobencil)piperidin-4il]amino}-2-hidroxi-2-metilpropil)oxi]-4-hidroxifenil}acetamida

Country Status (18)

Country Link
US (1) US8148405B2 (es)
EP (1) EP1912943A1 (es)
JP (1) JP2009503064A (es)
KR (1) KR20080031369A (es)
CN (1) CN101238103A (es)
AR (1) AR055365A1 (es)
AU (1) AU2006276344B2 (es)
BR (1) BRPI0614634A2 (es)
CA (1) CA2617403A1 (es)
EC (1) ECSP088219A (es)
IL (1) IL188474A0 (es)
MX (1) MX2008001113A (es)
NO (1) NO20081080L (es)
RU (1) RU2417220C2 (es)
TW (1) TW200738634A (es)
UY (1) UY29714A1 (es)
WO (1) WO2007015666A1 (es)
ZA (1) ZA200800515B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR028948A1 (es) * 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
WO2008100202A1 (en) * 2007-02-14 2008-08-21 Astrazeneca Ab A 2-f luorobenzoate salt and a 2, 6-dif luorobenzoate salt of n-{5-chloro-2- [ ( (2s) -3-{ [1- (4-chlorobenzyl)piperidin-4- yl ] amino } - 2 - hydroxy- 2 -me t hylpr opyl ) oxy] - 4 - hydroxyphenyl } acetamide
GB0814729D0 (en) * 2008-08-12 2008-09-17 Argenta Discovery Ltd New combination

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1220440B (de) * 1962-02-14 1966-07-07 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von Derivaten des 1-(o-Bromphenoxy)-2-hydroxy-3-amino-propans und deren Saeureadditionssalzen
US3577432A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-phenoxypyrrolidines
US4029801A (en) * 1970-09-03 1977-06-14 John Wyeth & Brother Limited Pharmaceutical compositions and methods of treating hypertension
JPS5511670B1 (es) 1971-07-13 1980-03-26
US4080328A (en) * 1971-07-13 1978-03-21 Sumitomo Chemical Company, Limited N-substituted heterocyclic derivatives and preparation thereof
US3994974A (en) * 1972-02-05 1976-11-30 Yamanouchi Pharmaceutical Co., Ltd. α-Aminomethylbenzyl alcohol derivatives
US3755584A (en) * 1972-04-03 1973-08-28 Abbott Lab Tranquilizers
SE378109B (es) 1972-05-19 1975-08-18 Bofors Ab
FR2190430A1 (en) 1972-06-29 1974-02-01 Ferlux N-aminomethylhydroxamic acids - with antiinflammatory activity pre-pared by Mannich reaction
US3818017A (en) * 1973-01-04 1974-06-18 Janssen Pharmaceutica Nv 1-{8 1-(2-hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
US3894030A (en) * 1973-01-04 1975-07-08 Janssen Pharmaceutica Nv 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
US4166119A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
US4264613A (en) * 1979-08-01 1981-04-28 Science Union Et Cie, Societe Francaise De Recherche Medicale Piperidylbenzimidazolinone compounds
FR2469411A1 (fr) * 1979-11-15 1981-05-22 Science Union & Cie Nouveaux derives de la piperidylbenzimidazolinone, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
EP0095454A3 (de) 1982-05-13 1985-04-03 Gerot-Pharmazeutika Gesellschaft m.b.H. Neue kernsubstituierte Pyrogallol-Derivate
JPS59222484A (ja) 1983-06-02 1984-12-14 Kowa Co テトラヒドロナフチルカルボン酸フエニルエステル誘導体
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
US5614533A (en) * 1987-03-13 1997-03-25 Bio-Mega/Boehringer Ingelheim Research, Inc. Substituted pipecolinic acid derivatives as HIV protease inhibitors
DE3723648A1 (de) 1987-07-17 1989-01-26 Sandoz Ag Indol-derivate, ihre herstellung und sie enthaltende arzneimittel
GR1001529B (el) 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
SE9003057D0 (sv) 1990-09-26 1990-09-26 Astra Ab New process
ES2027897A6 (es) 1991-01-24 1992-06-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina.
IL105716A0 (en) 1992-06-08 1993-09-22 Richter Gedeon Vegyeszet Aminopropanol derivatives,their preparation and pharmaceutical compositions containing them
AU662434B2 (en) 1992-08-07 1995-08-31 Sankyo Company Limited Peptides capable of inhibiting the activity of HIV protease, their preparation and their use
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5741789A (en) * 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
BR9707495A (pt) 1996-02-13 1999-07-27 Zeneca Ltd Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
KR100489174B1 (ko) 1996-03-05 2005-09-30 제네카-파마 소시에떼아노님 4-아닐리노퀴나졸린유도체
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
DE19703131A1 (de) 1997-01-29 1998-07-30 Bayer Ag Verwendung von Chinoxalin in Dreier-Kombination mit Protease-Inhibitoren und Reverse Transkriptaseinhibitoren als Arzneimittel zur Behandlung von AIDS und/oder HIV-Infektionen
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
WO1999025686A1 (en) 1997-11-18 1999-05-27 Teijin Limited Cyclic amine derivatives and their use as drugs
DE19755268A1 (de) 1997-12-12 1999-06-17 Merck Patent Gmbh Benzamidinderivate
FR2780057B1 (fr) 1998-06-18 2002-09-13 Sanofi Sa Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant
DE69938193D1 (de) * 1998-11-20 2008-04-03 Hoffmann La Roche Piperidin ccr-3 rezeptor-hemmer
CA2350730A1 (en) 1998-12-18 2000-06-22 George V. Delucca N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
EP1156807A4 (en) 1998-12-18 2002-04-03 Du Pont Pharm Co N-UREIDOALKYL-PIPERIDINES FOR USE AS MODULATORS OF THE ACTIVITY OF CHIMIOKIN RECEPTORS
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
SE9900833D0 (sv) 1999-03-09 1999-03-09 Astra Ab Novel combination
AU2942000A (en) 1999-03-11 2000-09-28 Banyu Pharmaceutical Co., Ltd. Novel piperidine derivatives
KR20010108394A (ko) 1999-03-26 2001-12-07 다비드 에 질레스 신규 화합물
GB9913083D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds
DE60014361T2 (de) 1999-05-14 2006-02-02 Bristol-Myers Squibb Pharma Research Labs, Inc. Zyklische aminderivate und ihre verwendung
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
SE9902987D0 (sv) 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
FR2802533B1 (fr) 1999-12-17 2002-02-15 Sanofi Synthelabo Phenoxypropanolamines, leur preparation et leur application en therapeutique
US6867220B2 (en) 1999-12-17 2005-03-15 Sanofi-Synthelabo Phenoxypropanolamines, method for producing them and pharmaceutical compositions containing them
CO5300399A1 (es) 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
GB0011838D0 (en) 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
GB0012260D0 (en) * 2000-05-19 2000-07-12 Astrazeneca Ab Novel composition
IL152682A0 (en) 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
AR028947A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
AR028948A1 (es) * 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
US7005439B2 (en) * 2000-06-20 2006-02-28 Astrazeneca Ab Compounds
JP2004516238A (ja) 2000-06-21 2004-06-03 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー ケモカイン受容体活性調節剤としてのｎ−ウレイドアルキル−ピペリジン
GB0015876D0 (en) 2000-06-28 2000-08-23 Novartis Ag Organic compounds
KR20030022264A (ko) 2000-07-07 2003-03-15 앤지오젠 파마슈티칼스 리미티드 신생 혈관 형성 억제제인 콜치놀 유도체
US20050277627A1 (en) 2000-07-07 2005-12-15 Arnould Jean C Colchinol derivatives as vascular damaging agents
IL154175A0 (en) 2000-08-05 2003-07-31 Glaxo Group Ltd 17. beta.-carbothioate 17. alpha-arylcarbonyloxyloxy androstane derivatives as anti-inflammatory agents
GB0021670D0 (en) * 2000-09-04 2000-10-18 Astrazeneca Ab Chemical compounds
GB0029562D0 (en) 2000-12-04 2001-01-17 Novartis Ag Organic compounds
GB2373186A (en) 2001-02-23 2002-09-18 Astrazeneca Ab Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation
AR035230A1 (es) 2001-03-19 2004-05-05 Astrazeneca Ab Compuestos de bencimidazol, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de dicha composicion farmaceutica, y usos de estos compuestos para la elaboracion de medicamentos
GB0107228D0 (en) 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds
WO2002076933A1 (en) 2001-03-22 2002-10-03 Glaxo Group Limited Formailide derivatives as beta2-adrenoreceptor agonists
SE0101038D0 (sv) * 2001-03-23 2001-03-23 Astrazeneca Ab Novel compounds
GB0108046D0 (en) 2001-03-30 2001-05-23 Astrazeneca Ab Chemical compounds
CA2445348A1 (en) 2001-04-27 2002-11-07 Mitsubishi Pharma Corporation Novel benzylpiperidine compound
SE0104251D0 (sv) * 2001-12-14 2001-12-14 Astrazeneca Ab Novel compounds
TW200303304A (en) * 2002-02-18 2003-09-01 Astrazeneca Ab Chemical compounds
CA2534125A1 (en) * 2003-07-29 2005-02-17 Boehringer Ingelheim International Gmbh Medicaments comprising pde iv inhibitors and an anticholinergic for treating respiratory disorders
SG137859A1 (en) * 2003-11-03 2007-12-28 Boehringer Ingelheim Int Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
EP1912942A1 (en) * 2005-08-01 2008-04-23 AstraZeneca AB Novel piperidine derivatives as chemokine receptor modulators useful for the treatment of respiratory diseases.
TW200734305A (en) * 2005-08-02 2007-09-16 Astrazeneca Ab New salt III
TW200738635A (en) * 2005-08-02 2007-10-16 Astrazeneca Ab New salt
JP2009506029A (ja) * 2005-08-26 2009-02-12 アストラゼネカ・アクチエボラーグ 呼吸器疾患、特に慢性閉塞性肺疾患（ｃｏｐｄ）および喘息の処置に使用し得る化合物の組み合わせ
TW200744612A (en) * 2005-08-26 2007-12-16 Astrazeneca Ab New combination
TW200800895A (en) * 2005-11-02 2008-01-01 Astrazeneca Ab Novel compounds
US20100041905A1 (en) * 2006-07-18 2010-02-18 Astrazeneca Ab Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl

Also Published As

Publication number Publication date
RU2417220C2 (ru) 2011-04-27
UY29714A1 (es) 2007-02-28
CA2617403A1 (en) 2007-02-08
AU2006276344B2 (en) 2010-10-07
RU2008105972A (ru) 2009-09-10
AU2006276344A1 (en) 2007-02-08
MX2008001113A (es) 2008-03-11
US8148405B2 (en) 2012-04-03
IL188474A0 (en) 2008-04-13
BRPI0614634A2 (pt) 2011-04-12
US20080227817A1 (en) 2008-09-18
ZA200800515B (en) 2008-12-31
CN101238103A (zh) 2008-08-06
JP2009503064A (ja) 2009-01-29
KR20080031369A (ko) 2008-04-08
EP1912943A1 (en) 2008-04-23
TW200738634A (en) 2007-10-16
WO2007015666A1 (en) 2007-02-08
ECSP088219A (es) 2008-03-26
NO20081080L (no) 2008-02-29

Similar Documents

Publication Publication Date Title
IL196462A (en) (s) - n - (3 - chloro - 4 - cyanophenyl) - 3 - (4 - cyanophenoxy) - 2 - hydroxy - 2 - methylpropanamide, composition and use
BR112013023739A2 (pt) cartuchos de campo cirúrgicos com cordões de tecido para manipular tecido dividido e método de uso dos mesmos
NO20085420L (no) Farmasøytisk formulering med fenylefrin og preparater for absorpsjon i tykktarmen
AR065278A1 (es) Sales de derivado de benzotiazol
BRPI0809667A2 (pt) Composto, medicamento e composição farmacêutica que o contém e uso do composto
ES2551157T3 (es) Uso de glucosilglicerol
ECSP077401A (es) Medicamentos que contienen compuestos de carbonilo y su uso
CR10663A (es) 4-[4-({[4-cloro-3-(trifluorometil)fenil]carbamoil}amino)-3-fluorofenoxi]-n-metilpiridina-2-carboxamida monohidrato
CU23932B1 (es) Sales farmacéuticamente aceptables de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo y sus usos en terapia
AR054261A1 (es) Sales fisiologicamente compatibles de ester etilico del acido 3-(2-{(4-(hexiloxicarbonilamino-imino-metil )-fenilamino]-metil}-1-metil-1h-bencimidazol-5-carbonil)-piridin-2-il-amino)-propionico, composiciones farmaceuticas que las contienen y su uso en la preparacion de un medicamento para la profil
DK2436378T3 (da) Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger
ECSP11010948A (es) Inhibidores de las enzimas de proteína cinasa activadas por
ATE549317T1 (de) Pharmazeutische salze und polymorphe aus n-(5- chloro-2-pyridinyl)-2-ää4- ä(dimethylamino)iminomethylübenzoylüaminoü-5- methoxy-benzamid, einem faktor-xa-hemmer
BRPI0808293A2 (pt) "composições para administração nasal"
CL2008000500A1 (es) Combinacion farmaceutica que comprende una combinacion de dos o mas broncodilatadores o una combinacion de al menos un broncodilatador y al menos un corticosteroide; uso para tratar o prevenir una enfermedad respiratoria; e inhalador que comprende di
CL2007002526A1 (es) Un medicamento que comprende, separado o juntos: a) una sal de glicopirronio; b) un agonista del adreno-receptor beta-2 seleccionado de salmeterol y formoterol; y c) un corticosteroide; kit farmaceutico; y uso en el tratamiento de una enfermedad infl
ECSP088296A (es) Compuestos terapéuticos
BRPI0607474A2 (pt) vacinação enriquecida com glicosido-alquila
CY1118976T1 (el) Κρυσταλλικες τροποποιησεις της (1r,2r)-3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολης
ECSP088287A (es) Una combinación de compuestos que puede ser utilizada en el tratamiento de enfermedades respiratorias, especialmente enfermedad pulmonar obstructiva crónica (epoc) y asma
SV2011003852A (es) Particulas inhalables que comprenden tiotropio
BRPI0717369A2 (pt) Composto, medicamento, composição farmacêutica que o contém e uso do composto.
CL2006003449A1 (es) Compuestos derivados de n-(fluoro-pirazinil)-fenilsulfonamidas; procedimiento de preparacion; compuesto intermediario; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del asma.
CL2007003501A1 (es) Un compuesto (e)-n-{3-[1-(8-cloro-11h-10-oxa-1-aza-dibenzo[a,d]ciclohepten-5-iliden)propil]-fenil}-metansulfonamida o una sal del mismo; composicion farmaceutica; y uso para el tratamiento de artritis reumatoide, asma, epoc, entre otras.
AR055365A1 (es) Benzoato de n{2-[((2s)-3-{[1-(4-clorobencil)piperidin-4il]amino}-2-hidroxi-2-metilpropil)oxi]-4-hidroxifenil}acetamida

Legal Events

Date Code Title Description
FB Suspension of granting procedure