AR055050A1 - Composicion farmaceutica que comprende n-etil-9a, 11a, 15s- trihidoxi-17-fenil-18,19,20-trinor-prosta -5z, 13e- dien-1-amida (bimatoprost) y cloruro de benzalconio, y uso de estos compuestos par la preparacion de la misma - Google Patents

Composicion farmaceutica que comprende n-etil-9a, 11a, 15s- trihidoxi-17-fenil-18,19,20-trinor-prosta -5z, 13e- dien-1-amida (bimatoprost) y cloruro de benzalconio, y uso de estos compuestos par la preparacion de la misma

Info

Publication number
AR055050A1
AR055050A1 ARP060101023A ARP060101023A AR055050A1 AR 055050 A1 AR055050 A1 AR 055050A1 AR P060101023 A ARP060101023 A AR P060101023A AR P060101023 A ARP060101023 A AR P060101023A AR 055050 A1 AR055050 A1 AR 055050A1
Authority
AR
Argentina
Prior art keywords
bimatoprost
pharmaceutical composition
trinor
prosta
trihidoxi
Prior art date
Application number
ARP060101023A
Other languages
English (en)
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36613401&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR055050(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of AR055050A1 publication Critical patent/AR055050A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Composicion farmacéutica que comprende de 0,005% a 0,02% en peso de N-etil-9a,11a,15S-trihidroxi-17-fenil-18,19,20-trinor- prosta-5Z,13E-dien-1-amida [o etil amida de 17-fenil trinor prostaglandina F2a] (bimatoprost) y de 100 ppm a 250ppm de cloruro de benzalconio, en donde dicha composicion es un líquido acuoso formulado para administracion oftálmica. Puede comprender además una cantidad efectiva de un agente quelante, por ejemplo hasta 0,03% de EDTA, un regulador de pH de fosfato y ClNa. Uso de bimatoprost y cloruro de benzalconio para preparar una composicion farmacéutica util para tratar glaucoma o hipertension ocular.
ARP060101023A 2005-03-16 2006-03-15 Composicion farmaceutica que comprende n-etil-9a, 11a, 15s- trihidoxi-17-fenil-18,19,20-trinor-prosta -5z, 13e- dien-1-amida (bimatoprost) y cloruro de benzalconio, y uso de estos compuestos par la preparacion de la misma AR055050A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/083,261 US7851504B2 (en) 2005-03-16 2005-03-16 Enhanced bimatoprost ophthalmic solution

Publications (1)

Publication Number Publication Date
AR055050A1 true AR055050A1 (es) 2007-08-01

Family

ID=36613401

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060101023A AR055050A1 (es) 2005-03-16 2006-03-15 Composicion farmaceutica que comprende n-etil-9a, 11a, 15s- trihidoxi-17-fenil-18,19,20-trinor-prosta -5z, 13e- dien-1-amida (bimatoprost) y cloruro de benzalconio, y uso de estos compuestos par la preparacion de la misma

Country Status (23)

Country Link
US (10) US7851504B2 (es)
EP (1) EP1753434B2 (es)
JP (3) JP5367946B2 (es)
KR (2) KR20120068051A (es)
CN (2) CN102240292B (es)
AR (1) AR055050A1 (es)
AT (1) ATE431152T1 (es)
AU (1) AU2006227757B2 (es)
BR (1) BRPI0607447B1 (es)
CA (1) CA2585691C (es)
DE (1) DE602006006762D1 (es)
DK (1) DK1753434T4 (es)
ES (1) ES2324058T5 (es)
HK (1) HK1104211A1 (es)
IL (1) IL185744A (es)
MX (1) MX2007011300A (es)
NO (1) NO337190B1 (es)
NZ (1) NZ560788A (es)
PL (1) PL1753434T5 (es)
RU (1) RU2363471C2 (es)
TW (1) TWI399207B (es)
WO (1) WO2006101839A2 (es)
ZA (1) ZA200707246B (es)

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