IT1313610B1 - Processo per la preparazione di formulazioni acquose per uso oftalmico - Google Patents

Processo per la preparazione di formulazioni acquose per uso oftalmico

Info

Publication number
IT1313610B1
IT1313610B1 IT1999MI001803A ITMI991803A IT1313610B1 IT 1313610 B1 IT1313610 B1 IT 1313610B1 IT 1999MI001803 A IT1999MI001803 A IT 1999MI001803A IT MI991803 A ITMI991803 A IT MI991803A IT 1313610 B1 IT1313610 B1 IT 1313610B1
Authority
IT
Italy
Prior art keywords
preparation
aqueous formulations
ophthalmic use
ophthalmic
formulations
Prior art date
Application number
IT1999MI001803A
Other languages
English (en)
Inventor
Antonino Asero
Maria Grazia Mazzone
Valeria Moschetti
Anna Rita Blanco
Original Assignee
S I F I Societa Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S I F I Societa Ind Farmaceuti filed Critical S I F I Societa Ind Farmaceuti
Publication of ITMI991803A0 publication Critical patent/ITMI991803A0/it
Priority to IT1999MI001803A priority Critical patent/IT1313610B1/it
Priority to EP99125642A priority patent/EP1075837B1/en
Priority to PT99125642T priority patent/PT1075837E/pt
Priority to DE69907664T priority patent/DE69907664T2/de
Priority to ES99125642T priority patent/ES2193658T3/es
Priority to AT99125642T priority patent/ATE239448T1/de
Priority to DK99125642T priority patent/DK1075837T3/da
Priority to US09/472,209 priority patent/US6277829B1/en
Priority to MXPA00007530A priority patent/MXPA00007530A/es
Priority to CA002315594A priority patent/CA2315594A1/en
Priority to JP2000240196A priority patent/JP2001089378A/ja
Publication of ITMI991803A1 publication Critical patent/ITMI991803A1/it
Application granted granted Critical
Publication of IT1313610B1 publication Critical patent/IT1313610B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT1999MI001803A 1999-08-09 1999-08-09 Processo per la preparazione di formulazioni acquose per uso oftalmico IT1313610B1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT1999MI001803A IT1313610B1 (it) 1999-08-09 1999-08-09 Processo per la preparazione di formulazioni acquose per uso oftalmico
DK99125642T DK1075837T3 (da) 1999-08-09 1999-12-22 Fremgangsmåde til fremstilling af vandige formuleringer til ophtalmisk anvendelse
PT99125642T PT1075837E (pt) 1999-08-09 1999-12-22 Processo de preparacao de formulacoes aquosas para utilizacao oftalmicas
DE69907664T DE69907664T2 (de) 1999-08-09 1999-12-22 Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung
ES99125642T ES2193658T3 (es) 1999-08-09 1999-12-22 Procedimiento para la preparacion de formulaciones acuosas para uso oftalmico.
AT99125642T ATE239448T1 (de) 1999-08-09 1999-12-22 Verfahren zur herstellung von wässrigen formulierungen für ophthalmische verwendung
EP99125642A EP1075837B1 (en) 1999-08-09 1999-12-22 Process for the preparation of aqueous formulations for ophthalmic use
US09/472,209 US6277829B1 (en) 1999-08-09 1999-12-27 Process for preparing of aqueous formulation for opthalmic use
MXPA00007530A MXPA00007530A (es) 1999-08-09 2000-08-01 Proceso para la preparacion de formulaciones acuosas para uso oftalmico.
CA002315594A CA2315594A1 (en) 1999-08-09 2000-08-08 Process for the preparation of aqueous formulations for ophthalmic use
JP2000240196A JP2001089378A (ja) 1999-08-09 2000-08-08 眼科用水性薬剤の製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001803A IT1313610B1 (it) 1999-08-09 1999-08-09 Processo per la preparazione di formulazioni acquose per uso oftalmico

Publications (3)

Publication Number Publication Date
ITMI991803A0 ITMI991803A0 (it) 1999-08-09
ITMI991803A1 ITMI991803A1 (it) 2001-02-09
IT1313610B1 true IT1313610B1 (it) 2002-09-09

Family

ID=11383545

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI001803A IT1313610B1 (it) 1999-08-09 1999-08-09 Processo per la preparazione di formulazioni acquose per uso oftalmico

Country Status (11)

Country Link
US (1) US6277829B1 (it)
EP (1) EP1075837B1 (it)
JP (1) JP2001089378A (it)
AT (1) ATE239448T1 (it)
CA (1) CA2315594A1 (it)
DE (1) DE69907664T2 (it)
DK (1) DK1075837T3 (it)
ES (1) ES2193658T3 (it)
IT (1) IT1313610B1 (it)
MX (1) MXPA00007530A (it)
PT (1) PT1075837E (it)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
WO2002007736A1 (en) * 2000-07-24 2002-01-31 Cadila Pharmaceuticals Limited The process for manufacturing of clear liquid pharmaceutical composition of azithromycin
HRP20010301A2 (en) * 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
EP1284143A1 (en) * 2001-08-17 2003-02-19 Sifi S.p.A A process for the preparation of pharmaceutical formulations containing lactoferrin description
WO2003032922A2 (en) * 2001-10-18 2003-04-24 Teva Pharmaceutical Industries Ltd. Stabilized azithromycin compositions
US20090215735A1 (en) * 2002-02-25 2009-08-27 Alcon, Inc. Topical solution formulations containing a corticosteroid and a cyclodextrin
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
JP4629578B2 (ja) * 2003-01-22 2011-02-09 ニチバン株式会社 眼疾患治療用経皮吸収型製剤
ES2220229B1 (es) * 2003-05-29 2005-10-16 Quimica Sintetica, S.A. Sales de adicion de azitromicina y acido citrico y procedimiento para su obtencion.
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
ATE529117T1 (de) 2004-07-02 2011-11-15 Wakamoto Pharma Co Ltd Medizinische zusammensetzung auf wasserbasis mit azithromycin und herstellungsverfahren dafür
JP2007277095A (ja) * 2004-07-02 2007-10-25 Wakamoto Pharmaceut Co Ltd アジスロマイシン含有可逆性熱ゲル化水性組成物
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US9241918B2 (en) * 2005-03-16 2016-01-26 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
PT1906916E (pt) * 2005-05-10 2008-12-10 Alcon Inc Suspensão oftálmica compreendendo um fármaco oftálmico, uma poloxamina e um agente de ajuste da tonicidade de glicol, utilização da referida composição para a produção de um medicamento para o tratamento de distúrbios oftálmicos
JPWO2007074904A1 (ja) * 2005-12-28 2009-06-04 わかもと製薬株式会社 水性医薬組成物
FR2900575B1 (fr) * 2006-05-05 2008-10-17 Anteis Sa Gel biocompatible a liberation controlee, son procede de preparation et son utilisation
WO2008085913A1 (en) * 2007-01-04 2008-07-17 Rib-X Pharmaceuticals, Inc. Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections
BRPI0808410A2 (pt) * 2007-02-28 2015-06-23 Aciex Therapeutics Inc Métodos e composições para normalizar secreções da glândula meibomiana
US7795231B2 (en) * 2007-10-04 2010-09-14 Insite Vision Incorporated Concentrated aqueous azalide formulations
EP2098219A1 (en) 2008-03-05 2009-09-09 PARI Pharma GmbH Macrolide compositions having improved taste and stability
JP2011515494A (ja) * 2008-03-26 2011-05-19 エリック ドネンフェルド， テトラサイクリンファミリー抗生物質を用いる、眼瞼縁および涙液膜機能の改善ならびに眼瞼縁疾患の処置のための方法
WO2010006306A1 (en) * 2008-07-10 2010-01-14 Inspire Pharmaceuticals, Inc. Method of treating blepharitis
US20100190734A1 (en) * 2009-01-23 2010-07-29 Romulus Kimbro Brazzell Method of treating dry eye disease with azithromycin
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
CN103211755A (zh) * 2012-01-19 2013-07-24 武汉诺安药业有限公司 无菌稳定的阿奇霉素滴眼液的生产方法
RU2512683C2 (ru) 2012-06-08 2014-04-10 Общество с ограниченной ответственностью "ВИК-здоровье животных" Антибактериальная инъекционная фармацевтическая композиция
US20180042953A1 (en) * 2012-06-08 2018-02-15 Obshchestvo S Ogranichennoy Otvetstvennostyu "Vik - Zdorovye Zhivotnykh" Antibacterial injectable pharmaceutical composition
CN103860515A (zh) * 2012-12-10 2014-06-18 中国科学院上海药物研究所 阿奇霉素渗透泵控释片及其制备方法
US9044508B2 (en) 2013-03-15 2015-06-02 Insite Vision Corporation Concentrated aqueous azalide formulations
RS58731B1 (sr) * 2014-01-22 2019-06-28 Visufarma B V Kompozicija koja sadrži jota-karagenan protiv virusnog konjuktivitisa
RU2580630C1 (ru) * 2015-03-19 2016-04-10 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Антибактериальное лекарственное средство в форме капель для лечения глазных болезней у животных
RU2580631C1 (ru) * 2015-03-19 2016-04-10 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Антибактериальное лекарственное средство в форме мази для лечения глазных болезней у животных
US20180098937A1 (en) * 2016-10-12 2018-04-12 Ps Therapies Ltd Artificial tear, contact lens and drug vehicle compositions and methods of use thereof
CN114796116A (zh) * 2022-05-17 2022-07-29 中山大学附属第六医院 一种阿奇霉素吸入剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989002271A1 (en) * 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
CN1123279A (zh) * 1995-06-15 1996-05-29 沈家祥 阿奇霉素水溶性盐、其注射剂型以及它们的用途
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US5646151A (en) * 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
PT925789E (pt) * 1997-12-02 2004-10-29 Pfizer Prod Inc Es oculares utilizacao de azitromicina no tratamento topico de infecco

Also Published As

Publication number Publication date
CA2315594A1 (en) 2001-02-09
DE69907664D1 (de) 2003-06-12
ITMI991803A0 (it) 1999-08-09
MXPA00007530A (es) 2002-06-04
ITMI991803A1 (it) 2001-02-09
EP1075837A3 (en) 2001-05-16
EP1075837B1 (en) 2003-05-07
ATE239448T1 (de) 2003-05-15
EP1075837A2 (en) 2001-02-14
US6277829B1 (en) 2001-08-21
ES2193658T3 (es) 2003-11-01
DE69907664T2 (de) 2004-04-08
JP2001089378A (ja) 2001-04-03
PT1075837E (pt) 2003-08-29
DK1075837T3 (da) 2003-09-01

Similar Documents

Publication Publication Date Title
IT1313610B1 (it) Processo per la preparazione di formulazioni acquose per uso oftalmico
BR0209918A (pt) Formas cristalinas da azitromicina
WO2003010138A3 (en) Piperidine derivatives as antibacterial agents
BRPI0307702B8 (pt) formulações de solução contendo anticorpo
ATE430742T1 (de) Pyrimidinamine als angiogenesemodulatoren
EA200300948A1 (ru) Водная композиция амфотерицина b
CY1108542T1 (el) Εμβολιο πολυσακχαριτη για μολυνσεις απο σταφυλοκοκκο
PT925789E (pt) Es oculares utilizacao de azitromicina no tratamento topico de infecco
MA27046A1 (fr) Nouveaux derives d'oxazolidinones en tant qu'agents antibacteriens.
DK0903347T3 (da) Hidtil ukendte cyclodepsipeptid PF1022-derivater
ATE277062T1 (de) Neue makrolidderivate
CA2332686A1 (en) Novel 13 and 14-membered antibacterial and prokinetic macrolides and their intermediates
EP1436279B8 (en) Chemical compounds
WO2002070537A3 (en) Fusidic acid derivatives
PT1232173E (pt) Derivados do acido fusidico
BR9902049A (pt) Derivados 9a,11b-desidro de 9-oxima-3-ceto-6-o-metileritromicina.
EP1369426A4 (en) "NEW PEPTIDES, DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF, NEW STRAINS THAT PRODUCE THESE SUBSTANCES, AND ANTIVIRAL AGENTS CONTAINING SUCH SUBSTANCES AS ACTIVE AGENTS"
CA2536501A1 (en) Crystal forms of azithromycin
ATE338759T1 (de) 2-(aminomethyl)tetrahydro-9-oxa-1,3- diazacyclopentaca)naphthalinylderivate mit antipsychotischer wirkung
PT1140932E (pt) Derivados de 1,8-benzonaftiridina
AU2002333377A1 (en) 3-substituted 6,7-dihydroxytetrahydroisoquinoline derivatives for use as antibacterial agents
IT1301869B1 (it) Procedimento per la fabbricazione di montature per occhiali, inparticolare per la fabbricazione di un oculare per montature per