DE69907664D1 - Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung - Google Patents
Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische VerwendungInfo
- Publication number
- DE69907664D1 DE69907664D1 DE69907664T DE69907664T DE69907664D1 DE 69907664 D1 DE69907664 D1 DE 69907664D1 DE 69907664 T DE69907664 T DE 69907664T DE 69907664 T DE69907664 T DE 69907664T DE 69907664 D1 DE69907664 D1 DE 69907664D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- aqueous formulations
- ophthalmic use
- ophthalmic
- formulations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI001803A IT1313610B1 (it) | 1999-08-09 | 1999-08-09 | Processo per la preparazione di formulazioni acquose per uso oftalmico |
ITMI991803 | 1999-08-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69907664D1 true DE69907664D1 (de) | 2003-06-12 |
DE69907664T2 DE69907664T2 (de) | 2004-04-08 |
Family
ID=11383545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69907664T Expired - Fee Related DE69907664T2 (de) | 1999-08-09 | 1999-12-22 | Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung |
Country Status (11)
Country | Link |
---|---|
US (1) | US6277829B1 (de) |
EP (1) | EP1075837B1 (de) |
JP (1) | JP2001089378A (de) |
AT (1) | ATE239448T1 (de) |
CA (1) | CA2315594A1 (de) |
DE (1) | DE69907664T2 (de) |
DK (1) | DK1075837T3 (de) |
ES (1) | ES2193658T3 (de) |
IT (1) | IT1313610B1 (de) |
MX (1) | MXPA00007530A (de) |
PT (1) | PT1075837E (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7056893B2 (en) | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
WO2002007736A1 (en) * | 2000-07-24 | 2002-01-31 | Cadila Pharmaceuticals Limited | The process for manufacturing of clear liquid pharmaceutical composition of azithromycin |
HRP20010301A2 (en) * | 2001-04-27 | 2001-12-31 | Pliva D D | New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases |
EP1284143A1 (de) * | 2001-08-17 | 2003-02-19 | Sifi S.p.A | Verfahren zur Herstellung von pharmazeutischen Lactoferrin enthaltenden Formulierungen |
WO2003032922A2 (en) * | 2001-10-18 | 2003-04-24 | Teva Pharmaceutical Industries Ltd. | Stabilized azithromycin compositions |
US20090215735A1 (en) * | 2002-02-25 | 2009-08-27 | Alcon, Inc. | Topical solution formulations containing a corticosteroid and a cyclodextrin |
US20040023935A1 (en) * | 2002-08-02 | 2004-02-05 | Dey, L.P. | Inhalation compositions, methods of use thereof, and process for preparation of same |
US20040109826A1 (en) * | 2002-12-06 | 2004-06-10 | Dey, L.P. | Stabilized albuterol compositions and method of preparation thereof |
JP4629578B2 (ja) * | 2003-01-22 | 2011-02-09 | ニチバン株式会社 | 眼疾患治療用経皮吸収型製剤 |
ES2220229B1 (es) * | 2003-05-29 | 2005-10-16 | Quimica Sintetica, S.A. | Sales de adicion de azitromicina y acido citrico y procedimiento para su obtencion. |
US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
ATE529117T1 (de) | 2004-07-02 | 2011-11-15 | Wakamoto Pharma Co Ltd | Medizinische zusammensetzung auf wasserbasis mit azithromycin und herstellungsverfahren dafür |
JP2007277095A (ja) * | 2004-07-02 | 2007-10-25 | Wakamoto Pharmaceut Co Ltd | アジスロマイシン含有可逆性熱ゲル化水性組成物 |
US20060046970A1 (en) * | 2004-08-31 | 2006-03-02 | Insite Vision Incorporated | Topical otic compositions and methods of topical treatment of prevention of otic infections |
US7851504B2 (en) | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
US9241918B2 (en) * | 2005-03-16 | 2016-01-26 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
PT1906916E (pt) * | 2005-05-10 | 2008-12-10 | Alcon Inc | Suspensão oftálmica compreendendo um fármaco oftálmico, uma poloxamina e um agente de ajuste da tonicidade de glicol, utilização da referida composição para a produção de um medicamento para o tratamento de distúrbios oftálmicos |
JPWO2007074904A1 (ja) * | 2005-12-28 | 2009-06-04 | わかもと製薬株式会社 | 水性医薬組成物 |
FR2900575B1 (fr) * | 2006-05-05 | 2008-10-17 | Anteis Sa | Gel biocompatible a liberation controlee, son procede de preparation et son utilisation |
WO2008085913A1 (en) * | 2007-01-04 | 2008-07-17 | Rib-X Pharmaceuticals, Inc. | Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections |
BRPI0808410A2 (pt) * | 2007-02-28 | 2015-06-23 | Aciex Therapeutics Inc | Métodos e composições para normalizar secreções da glândula meibomiana |
US7795231B2 (en) * | 2007-10-04 | 2010-09-14 | Insite Vision Incorporated | Concentrated aqueous azalide formulations |
EP2098219A1 (de) | 2008-03-05 | 2009-09-09 | PARI Pharma GmbH | Makrolidzusammensetzungen mit verbessertem Geschmack und verbesserter Stabilität |
JP2011515494A (ja) * | 2008-03-26 | 2011-05-19 | エリック ドネンフェルド, | テトラサイクリンファミリー抗生物質を用いる、眼瞼縁および涙液膜機能の改善ならびに眼瞼縁疾患の処置のための方法 |
WO2010006306A1 (en) * | 2008-07-10 | 2010-01-14 | Inspire Pharmaceuticals, Inc. | Method of treating blepharitis |
US20100190734A1 (en) * | 2009-01-23 | 2010-07-29 | Romulus Kimbro Brazzell | Method of treating dry eye disease with azithromycin |
US9522153B2 (en) | 2009-12-22 | 2016-12-20 | Allergan, Inc. | Compositions and methods for lowering intraocular pressure |
CN103211755A (zh) * | 2012-01-19 | 2013-07-24 | 武汉诺安药业有限公司 | 无菌稳定的阿奇霉素滴眼液的生产方法 |
RU2512683C2 (ru) | 2012-06-08 | 2014-04-10 | Общество с ограниченной ответственностью "ВИК-здоровье животных" | Антибактериальная инъекционная фармацевтическая композиция |
US20180042953A1 (en) * | 2012-06-08 | 2018-02-15 | Obshchestvo S Ogranichennoy Otvetstvennostyu "Vik - Zdorovye Zhivotnykh" | Antibacterial injectable pharmaceutical composition |
CN103860515A (zh) * | 2012-12-10 | 2014-06-18 | 中国科学院上海药物研究所 | 阿奇霉素渗透泵控释片及其制备方法 |
US9044508B2 (en) | 2013-03-15 | 2015-06-02 | Insite Vision Corporation | Concentrated aqueous azalide formulations |
RS58731B1 (sr) * | 2014-01-22 | 2019-06-28 | Visufarma B V | Kompozicija koja sadrži jota-karagenan protiv virusnog konjuktivitisa |
RU2580630C1 (ru) * | 2015-03-19 | 2016-04-10 | Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" | Антибактериальное лекарственное средство в форме капель для лечения глазных болезней у животных |
RU2580631C1 (ru) * | 2015-03-19 | 2016-04-10 | Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" | Антибактериальное лекарственное средство в форме мази для лечения глазных болезней у животных |
US20180098937A1 (en) * | 2016-10-12 | 2018-04-12 | Ps Therapies Ltd | Artificial tear, contact lens and drug vehicle compositions and methods of use thereof |
CN114796116A (zh) * | 2022-05-17 | 2022-07-29 | 中山大学附属第六医院 | 一种阿奇霉素吸入剂及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989002271A1 (en) * | 1987-09-10 | 1989-03-23 | Pfizer | Azithromycin and derivatives as antiprotozoal agents |
CN1123279A (zh) * | 1995-06-15 | 1996-05-29 | 沈家祥 | 阿奇霉素水溶性盐、其注射剂型以及它们的用途 |
US5705190A (en) * | 1995-12-19 | 1998-01-06 | Abbott Laboratories | Controlled release formulation for poorly soluble basic drugs |
US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
PT925789E (pt) * | 1997-12-02 | 2004-10-29 | Pfizer Prod Inc | Es oculares utilizacao de azitromicina no tratamento topico de infecco |
-
1999
- 1999-08-09 IT IT1999MI001803A patent/IT1313610B1/it active
- 1999-12-22 ES ES99125642T patent/ES2193658T3/es not_active Expired - Lifetime
- 1999-12-22 PT PT99125642T patent/PT1075837E/pt unknown
- 1999-12-22 AT AT99125642T patent/ATE239448T1/de not_active IP Right Cessation
- 1999-12-22 DK DK99125642T patent/DK1075837T3/da active
- 1999-12-22 DE DE69907664T patent/DE69907664T2/de not_active Expired - Fee Related
- 1999-12-22 EP EP99125642A patent/EP1075837B1/de not_active Expired - Lifetime
- 1999-12-27 US US09/472,209 patent/US6277829B1/en not_active Expired - Fee Related
-
2000
- 2000-08-01 MX MXPA00007530A patent/MXPA00007530A/es active IP Right Grant
- 2000-08-08 CA CA002315594A patent/CA2315594A1/en not_active Abandoned
- 2000-08-08 JP JP2000240196A patent/JP2001089378A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2315594A1 (en) | 2001-02-09 |
ITMI991803A0 (it) | 1999-08-09 |
MXPA00007530A (es) | 2002-06-04 |
ITMI991803A1 (it) | 2001-02-09 |
EP1075837A3 (de) | 2001-05-16 |
EP1075837B1 (de) | 2003-05-07 |
ATE239448T1 (de) | 2003-05-15 |
EP1075837A2 (de) | 2001-02-14 |
US6277829B1 (en) | 2001-08-21 |
ES2193658T3 (es) | 2003-11-01 |
DE69907664T2 (de) | 2004-04-08 |
JP2001089378A (ja) | 2001-04-03 |
PT1075837E (pt) | 2003-08-29 |
IT1313610B1 (it) | 2002-09-09 |
DK1075837T3 (da) | 2003-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |