AR054394A1 - Derivados de 2- (1h-indolilsulfanil)-aril amina - Google Patents
Derivados de 2- (1h-indolilsulfanil)-aril aminaInfo
- Publication number
- AR054394A1 AR054394A1 ARP060102491A ARP060102491A AR054394A1 AR 054394 A1 AR054394 A1 AR 054394A1 AR P060102491 A ARP060102491 A AR P060102491A AR P060102491 A ARP060102491 A AR P060102491A AR 054394 A1 AR054394 A1 AR 054394A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- cycloalkyl
- group
- amino
- independently
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 6
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 101100495914 Arabidopsis thaliana ETL1 gene Proteins 0.000 abstract 1
- 101100243950 Arabidopsis thaliana PIE1 gene Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69200905P | 2005-06-17 | 2005-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR054394A1 true AR054394A1 (es) | 2007-06-20 |
Family
ID=37532681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060102491A AR054394A1 (es) | 2005-06-17 | 2006-06-13 | Derivados de 2- (1h-indolilsulfanil)-aril amina |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1893575B1 (https=) |
| JP (1) | JP5144507B2 (https=) |
| KR (1) | KR20080027462A (https=) |
| CN (1) | CN101238101A (https=) |
| AR (1) | AR054394A1 (https=) |
| AU (1) | AU2006257288A1 (https=) |
| BR (1) | BRPI0611748A2 (https=) |
| CA (1) | CA2611566C (https=) |
| EA (1) | EA200800070A1 (https=) |
| ES (1) | ES2616095T3 (https=) |
| IL (1) | IL188064A0 (https=) |
| MX (1) | MX2007014954A (https=) |
| NO (1) | NO20080265L (https=) |
| WO (1) | WO2006134499A2 (https=) |
| ZA (1) | ZA200710885B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101868233A (zh) * | 2007-09-24 | 2010-10-20 | H.隆德贝克有限公司 | 与血清素双重作用化合物有关的组合疗法 |
| TW200938189A (en) * | 2008-03-13 | 2009-09-16 | Lundbeck & Co As H | [2-(6-flouro-1H-indol-3-ylsulfanyl)benzyl]methyl amine for the treatment of affective disorders |
| US9000025B2 (en) | 2010-08-20 | 2015-04-07 | Amira Pharmaceuticals, Inc. | Autotaxin inhibitors and uses thereof |
| US9260416B2 (en) | 2011-05-27 | 2016-02-16 | Amira Pharmaceuticals, Inc. | Heterocyclic autotaxin inhibitors and uses thereof |
| CA2900604A1 (en) * | 2013-03-15 | 2014-09-25 | Chromocell Corporation | Sodium channel modulators for the treatment of pain |
| JP2016530210A (ja) | 2013-09-17 | 2016-09-29 | ファーマケア，インク． | ヘテロ環式ビニルオートタキシン阻害剤化合物 |
| US9714240B2 (en) | 2013-09-17 | 2017-07-25 | Pharmakea, Inc. | Vinyl autotaxin inhibitor compounds |
| JP2016531874A (ja) | 2013-09-26 | 2016-10-13 | ファーマケア，インク． | オートタキシン阻害剤化合物 |
| KR102515248B1 (ko) | 2013-11-22 | 2023-03-29 | 사브레 테라퓨틱스 엘엘씨 | 오토탁신 억제제 화합물 |
| MX2017015225A (es) | 2015-05-27 | 2018-02-19 | Pharmakea Inc | Inhibidores de la autotaxina y sus usos. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117129A (en) * | 1976-10-22 | 1978-09-26 | Warner-Lambert Company | Indolobenzoxazepines as cns depressants |
| ATE195125T1 (de) * | 1995-11-06 | 2000-08-15 | Dsm Nv | Verfahren zur de-esterifikation |
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| TW200400177A (en) * | 2002-06-04 | 2004-01-01 | Wyeth Corp | 1-(Aminoalkyl)-3-sulfonylindole and-indazole derivatives as 5-hydroxytryptamine-6 ligands |
| RS50589B (sr) * | 2003-12-23 | 2010-05-07 | H. Lundbeck A/S. | 2-(1h-indolilsulfanil)-benzil amin derivati kao ssri |
| AR052308A1 (es) * | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
-
2006
- 2006-06-13 AR ARP060102491A patent/AR054394A1/es not_active Application Discontinuation
- 2006-06-14 AU AU2006257288A patent/AU2006257288A1/en not_active Abandoned
- 2006-06-14 EA EA200800070A patent/EA200800070A1/ru unknown
- 2006-06-14 ES ES06808965.5T patent/ES2616095T3/es active Active
- 2006-06-14 ZA ZA200710885A patent/ZA200710885B/xx unknown
- 2006-06-14 BR BRPI0611748A patent/BRPI0611748A2/pt not_active IP Right Cessation
- 2006-06-14 EP EP06808965.5A patent/EP1893575B1/en active Active
- 2006-06-14 MX MX2007014954A patent/MX2007014954A/es not_active Application Discontinuation
- 2006-06-14 CN CNA2006800218382A patent/CN101238101A/zh active Pending
- 2006-06-14 KR KR1020077029334A patent/KR20080027462A/ko not_active Withdrawn
- 2006-06-14 JP JP2008516452A patent/JP5144507B2/ja not_active Expired - Fee Related
- 2006-06-14 CA CA2611566A patent/CA2611566C/en not_active Expired - Fee Related
- 2006-06-14 WO PCT/IB2006/002785 patent/WO2006134499A2/en not_active Ceased
-
2007
- 2007-12-11 IL IL188064A patent/IL188064A0/en unknown
-
2008
- 2008-01-15 NO NO20080265A patent/NO20080265L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2616095T3 (es) | 2017-06-09 |
| CA2611566A1 (en) | 2006-12-21 |
| AU2006257288A1 (en) | 2006-12-21 |
| WO2006134499A3 (en) | 2007-04-12 |
| NO20080265L (no) | 2008-01-15 |
| IL188064A0 (en) | 2008-03-20 |
| BRPI0611748A2 (pt) | 2016-11-22 |
| ZA200710885B (en) | 2009-03-25 |
| CN101238101A (zh) | 2008-08-06 |
| MX2007014954A (es) | 2008-02-15 |
| EP1893575A2 (en) | 2008-03-05 |
| EP1893575B1 (en) | 2017-01-11 |
| WO2006134499A2 (en) | 2006-12-21 |
| CA2611566C (en) | 2011-08-16 |
| EA200800070A1 (ru) | 2008-04-28 |
| JP2008546679A (ja) | 2008-12-25 |
| JP5144507B2 (ja) | 2013-02-13 |
| KR20080027462A (ko) | 2008-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |