AR042193A1 - Composiciones farmaceuticas que tienen un vehiculo modificado - Google Patents
Composiciones farmaceuticas que tienen un vehiculo modificadoInfo
- Publication number
- AR042193A1 AR042193A1 ARP030104227A ARP030104227A AR042193A1 AR 042193 A1 AR042193 A1 AR 042193A1 AR P030104227 A ARP030104227 A AR P030104227A AR P030104227 A ARP030104227 A AR P030104227A AR 042193 A1 AR042193 A1 AR 042193A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- liquid excipient
- modified
- unmodified
- composition according
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 6
- 239000007788 liquid Substances 0.000 abstract 5
- 239000012867 bioactive agent Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- ZBHXIWJRIFEVQY-IHMPYVIRSA-N ceftiofur Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC(=O)C1=CC=CO1 ZBHXIWJRIFEVQY-IHMPYVIRSA-N 0.000 abstract 1
- 229960005229 ceftiofur Drugs 0.000 abstract 1
- 239000003240 coconut oil Substances 0.000 abstract 1
- 235000019864 coconut oil Nutrition 0.000 abstract 1
- 235000012343 cottonseed oil Nutrition 0.000 abstract 1
- 239000002385 cottonseed oil Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 239000003981 vehicle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Composición que comprende: (a) uno a tres agentes bioactivos; y (b) un vehículo que comprende: (i) un excipiente líquido modificado, y (ii) un excipiente líquido no modificado en la que la relación en volumen del excipiente líquido modificado a excipiente no modificado es entre 0,00001:99,99999 y menos que 0,01:99,99, que proporciona la composición con propiedades de liberación sostenida predecibles, y en la que inmediatamente después de fabricar la composición, dicha composición se puede administrar a un receptor de forma que los uno a tres agentes bioactivos son liberados en el receptor de una forma sostenida. Reivindicación 3: La composición de acuerdo con la reivindicación 2, caracterizada porque dicha sustancia bioactiva comprende el ácido libre de ceftiofur cristalino. Reivindicación 7: La composición de acuerdo con la reivindicación 4, caracterizada porque dicho excipiente líquido modificado comprende aceite de semilla de algodón modificado. Reivindicación 8: La composición de acuerdo con la reivindicación 4, caracterizada porque dicho excipiente líquido no modificado comprende aceite de coco.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42768002P | 2002-11-19 | 2002-11-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR042193A1 true AR042193A1 (es) | 2005-06-15 |
Family
ID=32326579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP030104227A AR042193A1 (es) | 2002-11-19 | 2003-11-17 | Composiciones farmaceuticas que tienen un vehiculo modificado |
Country Status (18)
Country | Link |
---|---|
US (1) | US7659061B2 (es) |
EP (1) | EP1569693B1 (es) |
JP (1) | JP4656945B2 (es) |
KR (1) | KR20050085037A (es) |
CN (2) | CN103272243A (es) |
AR (1) | AR042193A1 (es) |
AU (1) | AU2003276594B2 (es) |
BR (1) | BR0316310A (es) |
CA (1) | CA2502025C (es) |
IL (1) | IL168183A (es) |
MX (1) | MXPA05005319A (es) |
NO (1) | NO20051688L (es) |
NZ (1) | NZ539923A (es) |
PL (1) | PL377740A1 (es) |
RU (1) | RU2401127C2 (es) |
TW (1) | TWI267379B (es) |
WO (1) | WO2004045646A1 (es) |
ZA (1) | ZA200503040B (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010036427A1 (en) | 2008-06-17 | 2010-04-01 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
CN104039369B (zh) | 2011-07-20 | 2017-06-16 | 布莱阿姆青年大学 | 疏水性塞拉集宁化合物和包含该化合物的装置 |
EP2755661A1 (en) | 2011-09-13 | 2014-07-23 | Brigham Young University | Compositions for treating bone diseases and broken bones |
BR112014005914B1 (pt) | 2011-09-13 | 2021-11-09 | Brigham Young University | Produtos para cicatrização de feridas tecidulares |
US9694019B2 (en) | 2011-09-13 | 2017-07-04 | Brigham Young University | Compositions and methods for treating bone diseases and broken bones |
US9603859B2 (en) | 2011-09-13 | 2017-03-28 | Brigham Young University | Methods and products for increasing the rate of healing of tissue wounds |
KR20140116111A (ko) | 2011-12-21 | 2014-10-01 | 브라이엄 영 유니버시티 | 구강 관리 조성물 |
US9533063B1 (en) | 2012-03-01 | 2017-01-03 | Brigham Young University | Aerosols incorporating ceragenin compounds and methods of use thereof |
CA2872399C (en) | 2012-05-02 | 2021-01-12 | Brigham Young University | Ceragenin particulate materials and methods for making same |
CA2888259C (en) | 2012-10-17 | 2019-05-28 | Brigham Young University | Treatment and prevention of mastitis |
CN105451742B (zh) | 2013-01-07 | 2021-04-06 | 布莱阿姆青年大学 | 减少细胞增殖和治疗某些疾病的方法 |
JP6518230B2 (ja) | 2013-03-15 | 2019-05-22 | ブリガム・ヤング・ユニバーシティBrigham Young University | 炎症、自己免疫疾患、および疼痛を治療する方法 |
US10568893B2 (en) | 2013-03-15 | 2020-02-25 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US11524015B2 (en) | 2013-03-15 | 2022-12-13 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US9387215B2 (en) | 2013-04-22 | 2016-07-12 | Brigham Young University | Animal feed including cationic cholesterol additive and related methods |
US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
US20150203527A1 (en) | 2014-01-23 | 2015-07-23 | Brigham Young University | Cationic steroidal antimicrobials |
CA2844321C (en) | 2014-02-27 | 2021-03-16 | Brigham Young University | Cationic steroidal antimicrobial compounds |
US10220045B2 (en) | 2014-03-13 | 2019-03-05 | Brigham Young University | Compositions and methods for forming stabilized compositions with reduced CSA agglomeration |
US9867836B2 (en) | 2014-03-13 | 2018-01-16 | Brigham Young University | Lavage and/or infusion using CSA compounds for increasing fertility in a mammal |
US9931350B2 (en) | 2014-03-14 | 2018-04-03 | Brigham Young University | Anti-infective and osteogenic compositions and methods of use |
WO2015158823A1 (de) | 2014-04-16 | 2015-10-22 | Veyx-Pharma Gmbh | Veterinärpharmazeutische zusammensetzung und deren verwendung |
US9686966B2 (en) | 2014-04-30 | 2017-06-27 | Brigham Young University | Methods and apparatus for cleaning or disinfecting a water delivery system |
US10238665B2 (en) | 2014-06-26 | 2019-03-26 | Brigham Young University | Methods for treating fungal infections |
US10441595B2 (en) | 2014-06-26 | 2019-10-15 | Brigham Young University | Methods for treating fungal infections |
US10227376B2 (en) | 2014-08-22 | 2019-03-12 | Brigham Young University | Radiolabeled cationic steroid antimicrobials and diagnostic methods |
US10155788B2 (en) | 2014-10-07 | 2018-12-18 | Brigham Young University | Cationic steroidal antimicrobial prodrug compositions and uses thereof |
US9527883B2 (en) | 2015-04-22 | 2016-12-27 | Brigham Young University | Methods for the synthesis of ceragenins |
US10370403B2 (en) | 2015-04-22 | 2019-08-06 | Brigham Young University | Methods for the synthesis of ceragenins |
US9434759B1 (en) | 2015-05-18 | 2016-09-06 | Brigham Young University | Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds |
US10226550B2 (en) | 2016-03-11 | 2019-03-12 | Brigham Young University | Cationic steroidal antimicrobial compositions for the treatment of dermal tissue |
US10959433B2 (en) | 2017-03-21 | 2021-03-30 | Brigham Young University | Use of cationic steroidal antimicrobials for sporicidal activity |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US110561A (en) * | 1870-12-27 | Improvement in children s carriages | ||
US4297353A (en) | 1980-08-04 | 1981-10-27 | Sandoz, Inc. | Non-irritating injectable dosage forms |
KR890002631B1 (ko) * | 1984-10-04 | 1989-07-21 | 몬산토 캄파니 | 생물학적으로 활성인 소마토트로핀을 지속적으로 유리하는 조성물 |
US5019395A (en) | 1988-03-08 | 1991-05-28 | Warner-Lambert Company | Compositions with enhanced penetration |
JP2856444B2 (ja) * | 1989-07-28 | 1999-02-10 | 呉羽化学工業株式会社 | ビタミンd▲下3▼代謝産物製剤 |
JP3078859B2 (ja) | 1990-02-23 | 2000-08-21 | 武田薬品工業株式会社 | 安定な放出制御性製剤用コーティング剤 |
FR2692480B1 (fr) | 1992-06-22 | 1995-12-08 | Technico Flor Sa | Nouvelles compositions cosmetiques ou alimentaires renfermant du copaiba. |
SK283674B6 (sk) * | 1993-03-12 | 2003-11-04 | Pharmacia & Upjohn Company | Kryštalická voľná kyselina ceftiofuru a spôsob jej prípravy a farmaceutická kompozícia, ktorá ju obsahuje |
DE4340879A1 (de) | 1993-12-01 | 1995-06-08 | Horst P O Dr Wolf | Arzneimittel zur Behandlung der Herzinsuffizienz |
EP0805678B1 (en) | 1995-01-05 | 2003-10-29 | THE BOARD OF REGENTS acting for and on behalf of THE UNIVERSITY OF MICHIGAN | Surface-modified nanoparticles and method of making and using same |
JP2000512649A (ja) | 1996-06-27 | 2000-09-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 徐放性スフェンタニル組成物 |
US5736151A (en) * | 1996-12-09 | 1998-04-07 | Pharmacia & Upjohn Company | Antibiotic oil suspensions |
US6074657A (en) * | 1997-03-20 | 2000-06-13 | Pharmacia & Upjohn Company | Administration of an injectable antibiotic in the ear of an animal |
JP2004508418A (ja) | 2000-09-12 | 2004-03-18 | ファルマシア・アンド・アップジョン・カンパニー | 特定の水分活性を持つ医薬組成物 |
PT1317256E (pt) * | 2000-09-12 | 2008-12-17 | Pharmacia & Upjohn Co Llc | Composição farmacêutica com veículo modificado |
-
2003
- 2003-11-12 US US10/706,255 patent/US7659061B2/en active Active
- 2003-11-17 EP EP03811460.9A patent/EP1569693B1/en not_active Expired - Lifetime
- 2003-11-17 MX MXPA05005319A patent/MXPA05005319A/es active IP Right Grant
- 2003-11-17 NZ NZ539923A patent/NZ539923A/en not_active IP Right Cessation
- 2003-11-17 PL PL377740A patent/PL377740A1/pl unknown
- 2003-11-17 AU AU2003276594A patent/AU2003276594B2/en not_active Ceased
- 2003-11-17 CN CN2013101785052A patent/CN103272243A/zh active Pending
- 2003-11-17 WO PCT/IB2003/005234 patent/WO2004045646A1/en active Application Filing
- 2003-11-17 CN CNA2003801036161A patent/CN1713923A/zh active Pending
- 2003-11-17 CA CA2502025A patent/CA2502025C/en not_active Expired - Lifetime
- 2003-11-17 RU RU2005115131/15A patent/RU2401127C2/ru active
- 2003-11-17 AR ARP030104227A patent/AR042193A1/es not_active Application Discontinuation
- 2003-11-17 JP JP2004553024A patent/JP4656945B2/ja not_active Expired - Lifetime
- 2003-11-17 KR KR1020057008917A patent/KR20050085037A/ko not_active Application Discontinuation
- 2003-11-17 BR BR0316310-5A patent/BR0316310A/pt not_active Application Discontinuation
- 2003-11-18 TW TW092132304A patent/TWI267379B/zh not_active IP Right Cessation
-
2005
- 2005-04-05 NO NO20051688A patent/NO20051688L/no not_active Application Discontinuation
- 2005-04-14 ZA ZA200503040A patent/ZA200503040B/en unknown
- 2005-04-21 IL IL168183A patent/IL168183A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20040170650A1 (en) | 2004-09-02 |
CA2502025C (en) | 2013-07-02 |
TW200427466A (en) | 2004-12-16 |
NO20051688D0 (no) | 2005-04-05 |
RU2401127C2 (ru) | 2010-10-10 |
RU2005115131A (ru) | 2005-10-27 |
JP2006514629A (ja) | 2006-05-11 |
CN1713923A (zh) | 2005-12-28 |
JP4656945B2 (ja) | 2011-03-23 |
WO2004045646A1 (en) | 2004-06-03 |
CA2502025A1 (en) | 2004-06-03 |
PL377740A1 (pl) | 2006-02-20 |
EP1569693A1 (en) | 2005-09-07 |
EP1569693B1 (en) | 2016-12-28 |
KR20050085037A (ko) | 2005-08-29 |
NO20051688L (no) | 2005-08-02 |
US7659061B2 (en) | 2010-02-09 |
MXPA05005319A (es) | 2005-07-25 |
NZ539923A (en) | 2007-02-23 |
IL168183A (en) | 2010-04-29 |
AU2003276594B2 (en) | 2009-01-08 |
ZA200503040B (en) | 2006-09-27 |
BR0316310A (pt) | 2005-09-27 |
CN103272243A (zh) | 2013-09-04 |
TWI267379B (en) | 2006-12-01 |
AU2003276594A1 (en) | 2004-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |