AR040717A1 - Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animales - Google Patents
Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animalesInfo
- Publication number
- AR040717A1 AR040717A1 AR20030102710A ARP030102710A AR040717A1 AR 040717 A1 AR040717 A1 AR 040717A1 AR 20030102710 A AR20030102710 A AR 20030102710A AR P030102710 A ARP030102710 A AR P030102710A AR 040717 A1 AR040717 A1 AR 040717A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- alkyl
- oncosis
- alkylamino
- radical
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 230000021603 oncosis Effects 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- -1 alkyl phosphocholines Chemical class 0.000 abstract 6
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940041181 antineoplastic drug Drugs 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 230000003211 malignant effect Effects 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 239000000824 cytostatic agent Substances 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39961502P | 2002-07-30 | 2002-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR040717A1 true AR040717A1 (es) | 2005-04-20 |
Family
ID=31495746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR20030102710A AR040717A1 (es) | 2002-07-30 | 2003-07-29 | Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animales |
Country Status (26)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8383605B2 (en) | 2002-07-30 | 2013-02-26 | Aeterna Zentaris Gmbh | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals |
| UA82322C2 (uk) | 2002-07-30 | 2008-04-10 | Центаріс Гмбх | Застосування алкілфосфохолінів в комбінації з протипухлинними лікарськими засобами |
| DE10324911B4 (de) | 2003-05-30 | 2005-08-18 | Siemens Ag | Röntgenvorrichtung mit partiellem digitalem Detektor und Verfahren zum Betrieb einer solchen |
| WO2006081452A2 (en) * | 2005-01-28 | 2006-08-03 | Robert Birch | Co-administration of perifosine with chemotherapeutics |
| EP1962862B1 (en) * | 2005-12-19 | 2013-09-04 | Æterna Zentaris GmbH | Alkyl phospholipid derivatives with reduced cytotoxicity and uses therof |
| US20070167408A1 (en) * | 2005-12-19 | 2007-07-19 | Zentaris Gmbh | Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof |
| EP1800684A1 (en) * | 2005-12-20 | 2007-06-27 | Zentaris GmbH | Novel alkyl phospholipid derivatives and uses thereof |
| US8703179B2 (en) | 2006-05-11 | 2014-04-22 | Kimberly-Clark Worldwide, Inc. | Mucosal formulation |
| CN103479604B (zh) * | 2007-07-30 | 2016-08-10 | 阿迪生物科学公司 | 作为mek抑制剂的包括多晶型物的n-(芳氨基)磺酰胺衍生物和组合物、其使用方法和制备方法 |
| AU2009324464B2 (en) * | 2008-12-11 | 2016-05-05 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| US8383607B2 (en) | 2010-03-31 | 2013-02-26 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2086026T3 (es) * | 1991-07-04 | 1996-06-16 | Asta Medica Ag | Farmaco con efecto antineoplasico que contiene como sustancia activa (2-(n-metil-piperidino)-etil)-fosfato de octadecilo y procedimiento para su preparacion. |
| US5942639A (en) * | 1991-07-04 | 1999-08-24 | Asta Medica Aktiengesellschaft | Process for the preparation of alkylphosphocholines and the production thereof in pure form |
| US6172050B1 (en) * | 1992-07-11 | 2001-01-09 | Asta Medica Aktiengesellschaft | Phospholipid derivatives |
| JP3079993B2 (ja) * | 1996-03-27 | 2000-08-21 | 日本電気株式会社 | 真空マイクロデバイスおよびその製造方法 |
| DE19650778C2 (de) * | 1996-12-06 | 2001-01-04 | Asta Medica Ag | Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie |
| CA2318260C (en) | 1998-01-22 | 2006-11-21 | Asta Medica Ag | Solid pharmaceutical compositions containing miltefosine for oral administration in the treatment of leishmaniasis |
| JP2002531534A (ja) * | 1998-12-04 | 2002-09-24 | マックス−デルブルック−セントラム フュール モレクラーレ メディツィン | タモキシフェン含有リポソーム系腫瘍治療剤 |
| US6583127B1 (en) | 1998-12-21 | 2003-06-24 | Inkeysa. Sa | Use of etherlysophospholipids as antiinflammatory agents |
| CN1551767A (zh) * | 2001-02-19 | 2004-12-01 | ��˹��ŵ�� | 癌症的治疗 |
| ATE450265T1 (de) * | 2001-03-23 | 2009-12-15 | Shire Canada Inc | Pharmazeutische mischung zur behandlung von krebs,die dioxolan nukleosidanalogen enthält |
| WO2003005522A1 (es) | 2001-07-04 | 2003-01-16 | Acuna Arturo | Tapones para sellado de ductos para redes electricas, telefonicas y de fibra optica. |
| DE60210329T2 (de) * | 2002-01-02 | 2006-11-30 | Nerviano Medical Sciences S.R.L., Nerviano | Kombinierte tumortherapie auf der basis von substituierten acryloyl-distamycin-derivaten und protein-kinase (serin/threonin-kinase) inhibitoren |
| UA82322C2 (uk) | 2002-07-30 | 2008-04-10 | Центаріс Гмбх | Застосування алкілфосфохолінів в комбінації з протипухлинними лікарськими засобами |
| WO2005000318A2 (en) * | 2003-06-23 | 2005-01-06 | Neopharm, Inc. | Method of inducing apoptosis and inhibiting cardiolipin synthesis |
| WO2006081452A2 (en) | 2005-01-28 | 2006-08-03 | Robert Birch | Co-administration of perifosine with chemotherapeutics |
| US20070167408A1 (en) | 2005-12-19 | 2007-07-19 | Zentaris Gmbh | Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof |
| US8383607B2 (en) | 2010-03-31 | 2013-02-26 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
-
2003
- 2003-07-29 UA UAA200500510A patent/UA82322C2/uk unknown
- 2003-07-29 AR AR20030102710A patent/AR040717A1/es unknown
- 2003-07-29 CN CNB038181010A patent/CN1302780C/zh not_active Expired - Fee Related
- 2003-07-29 RU RU2005105693/15A patent/RU2005105693A/ru unknown
- 2003-07-29 MX MXPA05001203A patent/MXPA05001203A/es active IP Right Grant
- 2003-07-29 DK DK03766336.6T patent/DK1545553T3/da active
- 2003-07-29 SI SI200332027T patent/SI1545553T1/sl unknown
- 2003-07-29 CA CA2493023A patent/CA2493023C/en not_active Expired - Lifetime
- 2003-07-29 PT PT03766336T patent/PT1545553E/pt unknown
- 2003-07-29 HR HRP20050184AA patent/HRP20050184B1/hr not_active IP Right Cessation
- 2003-07-29 WO PCT/EP2003/008346 patent/WO2004012744A1/de not_active Ceased
- 2003-07-29 BR BR0313048-7A patent/BR0313048A/pt not_active IP Right Cessation
- 2003-07-29 AT AT03766336T patent/ATE516036T1/de active
- 2003-07-29 JP JP2004525354A patent/JP2005535688A/ja active Pending
- 2003-07-29 ES ES03766336T patent/ES2369535T3/es not_active Expired - Lifetime
- 2003-07-29 EP EP03766336A patent/EP1545553B1/de not_active Expired - Lifetime
- 2003-07-29 AU AU2003253350A patent/AU2003253350B2/en not_active Ceased
- 2003-07-29 KR KR1020057001510A patent/KR101066804B1/ko not_active Expired - Lifetime
- 2003-07-29 KR KR1020127034433A patent/KR20130016413A/ko not_active Ceased
- 2003-07-29 KR KR1020117017914A patent/KR20110102485A/ko not_active Ceased
- 2003-07-29 PL PL03375493A patent/PL375493A1/xx unknown
- 2003-07-29 TW TW092120705A patent/TWI332007B/zh not_active IP Right Cessation
- 2003-07-29 NZ NZ538428A patent/NZ538428A/en not_active IP Right Cessation
- 2003-07-29 EP EP10010451A patent/EP2301551A1/de not_active Withdrawn
- 2003-07-30 US US10/632,187 patent/US8389497B2/en not_active Expired - Fee Related
-
2005
- 2005-01-17 IL IL166329A patent/IL166329A/en not_active IP Right Cessation
- 2005-01-18 ZA ZA2005/00453A patent/ZA200500453B/en unknown
- 2005-02-25 NO NO20051040A patent/NO335196B1/no not_active IP Right Cessation
-
2008
- 2008-07-10 AU AU2008203060A patent/AU2008203060B2/en not_active Ceased
-
2010
- 2010-03-31 US US12/751,608 patent/US8507710B2/en not_active Expired - Fee Related
- 2010-03-31 US US12/751,454 patent/US8551977B2/en not_active Expired - Fee Related
-
2011
- 2011-09-30 CY CY20111100944T patent/CY1111902T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |