BR0313048A - Uso de alquilfosfocolinas em combinação com medicamentos antitumorais - Google Patents

Uso de alquilfosfocolinas em combinação com medicamentos antitumorais

Info

Publication number
BR0313048A
BR0313048A BR0313048-7A BR0313048A BR0313048A BR 0313048 A BR0313048 A BR 0313048A BR 0313048 A BR0313048 A BR 0313048A BR 0313048 A BR0313048 A BR 0313048A
Authority
BR
Brazil
Prior art keywords
combination
alkylphosphocholines
antitumor drugs
alkylphosphocolins
alkylphosphocolines
Prior art date
Application number
BR0313048-7A
Other languages
English (en)
Portuguese (pt)
Inventor
Juergen Engel
Eckhard Guenther
Herbert Sindermann
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of BR0313048A publication Critical patent/BR0313048A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR0313048-7A 2002-07-30 2003-07-29 Uso de alquilfosfocolinas em combinação com medicamentos antitumorais BR0313048A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39961502P 2002-07-30 2002-07-30
PCT/EP2003/008346 WO2004012744A1 (de) 2002-07-30 2003-07-29 Anwendung von alkylphosphocholinen in kombination mit antitumormedikamenten

Publications (1)

Publication Number Publication Date
BR0313048A true BR0313048A (pt) 2005-06-14

Family

ID=31495746

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313048-7A BR0313048A (pt) 2002-07-30 2003-07-29 Uso de alquilfosfocolinas em combinação com medicamentos antitumorais

Country Status (26)

Country Link
US (3) US8389497B2 (cg-RX-API-DMAC10.html)
EP (2) EP1545553B1 (cg-RX-API-DMAC10.html)
JP (1) JP2005535688A (cg-RX-API-DMAC10.html)
KR (3) KR101066804B1 (cg-RX-API-DMAC10.html)
CN (1) CN1302780C (cg-RX-API-DMAC10.html)
AR (1) AR040717A1 (cg-RX-API-DMAC10.html)
AT (1) ATE516036T1 (cg-RX-API-DMAC10.html)
AU (2) AU2003253350B2 (cg-RX-API-DMAC10.html)
BR (1) BR0313048A (cg-RX-API-DMAC10.html)
CA (1) CA2493023C (cg-RX-API-DMAC10.html)
CY (1) CY1111902T1 (cg-RX-API-DMAC10.html)
DK (1) DK1545553T3 (cg-RX-API-DMAC10.html)
ES (1) ES2369535T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20050184B1 (cg-RX-API-DMAC10.html)
IL (1) IL166329A (cg-RX-API-DMAC10.html)
MX (1) MXPA05001203A (cg-RX-API-DMAC10.html)
NO (1) NO335196B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ538428A (cg-RX-API-DMAC10.html)
PL (1) PL375493A1 (cg-RX-API-DMAC10.html)
PT (1) PT1545553E (cg-RX-API-DMAC10.html)
RU (1) RU2005105693A (cg-RX-API-DMAC10.html)
SI (1) SI1545553T1 (cg-RX-API-DMAC10.html)
TW (1) TWI332007B (cg-RX-API-DMAC10.html)
UA (1) UA82322C2 (cg-RX-API-DMAC10.html)
WO (1) WO2004012744A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA200500453B (cg-RX-API-DMAC10.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383605B2 (en) 2002-07-30 2013-02-26 Aeterna Zentaris Gmbh Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
UA82322C2 (uk) 2002-07-30 2008-04-10 Центаріс Гмбх Застосування алкілфосфохолінів в комбінації з протипухлинними лікарськими засобами
DE10324911B4 (de) 2003-05-30 2005-08-18 Siemens Ag Röntgenvorrichtung mit partiellem digitalem Detektor und Verfahren zum Betrieb einer solchen
WO2006081452A2 (en) * 2005-01-28 2006-08-03 Robert Birch Co-administration of perifosine with chemotherapeutics
EP1962862B1 (en) * 2005-12-19 2013-09-04 Æterna Zentaris GmbH Alkyl phospholipid derivatives with reduced cytotoxicity and uses therof
US20070167408A1 (en) * 2005-12-19 2007-07-19 Zentaris Gmbh Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
US8703179B2 (en) 2006-05-11 2014-04-22 Kimberly-Clark Worldwide, Inc. Mucosal formulation
CN103479604B (zh) * 2007-07-30 2016-08-10 阿迪生物科学公司 作为mek抑制剂的包括多晶型物的n-(芳氨基)磺酰胺衍生物和组合物、其使用方法和制备方法
AU2009324464B2 (en) * 2008-12-11 2016-05-05 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
US8383607B2 (en) 2010-03-31 2013-02-26 Aeterna Zentaris Gmbh Perifosine and capecitabine as a combined treatment for cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2086026T3 (es) * 1991-07-04 1996-06-16 Asta Medica Ag Farmaco con efecto antineoplasico que contiene como sustancia activa (2-(n-metil-piperidino)-etil)-fosfato de octadecilo y procedimiento para su preparacion.
US5942639A (en) * 1991-07-04 1999-08-24 Asta Medica Aktiengesellschaft Process for the preparation of alkylphosphocholines and the production thereof in pure form
US6172050B1 (en) * 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
JP3079993B2 (ja) * 1996-03-27 2000-08-21 日本電気株式会社 真空マイクロデバイスおよびその製造方法
DE19650778C2 (de) * 1996-12-06 2001-01-04 Asta Medica Ag Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie
CA2318260C (en) 1998-01-22 2006-11-21 Asta Medica Ag Solid pharmaceutical compositions containing miltefosine for oral administration in the treatment of leishmaniasis
JP2002531534A (ja) * 1998-12-04 2002-09-24 マックス−デルブルック−セントラム フュール モレクラーレ メディツィン タモキシフェン含有リポソーム系腫瘍治療剤
US6583127B1 (en) 1998-12-21 2003-06-24 Inkeysa. Sa Use of etherlysophospholipids as antiinflammatory agents
CN1551767A (zh) * 2001-02-19 2004-12-01 ��˹��ŵ�� 癌症的治疗
ATE450265T1 (de) * 2001-03-23 2009-12-15 Shire Canada Inc Pharmazeutische mischung zur behandlung von krebs,die dioxolan nukleosidanalogen enthält
WO2003005522A1 (es) 2001-07-04 2003-01-16 Acuna Arturo Tapones para sellado de ductos para redes electricas, telefonicas y de fibra optica.
DE60210329T2 (de) * 2002-01-02 2006-11-30 Nerviano Medical Sciences S.R.L., Nerviano Kombinierte tumortherapie auf der basis von substituierten acryloyl-distamycin-derivaten und protein-kinase (serin/threonin-kinase) inhibitoren
UA82322C2 (uk) 2002-07-30 2008-04-10 Центаріс Гмбх Застосування алкілфосфохолінів в комбінації з протипухлинними лікарськими засобами
WO2005000318A2 (en) * 2003-06-23 2005-01-06 Neopharm, Inc. Method of inducing apoptosis and inhibiting cardiolipin synthesis
WO2006081452A2 (en) 2005-01-28 2006-08-03 Robert Birch Co-administration of perifosine with chemotherapeutics
US20070167408A1 (en) 2005-12-19 2007-07-19 Zentaris Gmbh Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof
US8383607B2 (en) 2010-03-31 2013-02-26 Aeterna Zentaris Gmbh Perifosine and capecitabine as a combined treatment for cancer

Also Published As

Publication number Publication date
ZA200500453B (en) 2005-08-31
CA2493023C (en) 2012-01-31
EP1545553A1 (de) 2005-06-29
HRP20050184B1 (hr) 2014-04-11
SI1545553T1 (sl) 2011-09-30
US20100190738A1 (en) 2010-07-29
NZ538428A (en) 2006-09-29
CY1111902T1 (el) 2015-11-04
RU2005105693A (ru) 2005-07-10
PL375493A1 (en) 2005-11-28
UA82322C2 (uk) 2008-04-10
US8507710B2 (en) 2013-08-13
JP2005535688A (ja) 2005-11-24
AU2008203060B2 (en) 2011-04-21
KR20130016413A (ko) 2013-02-14
AU2003253350B2 (en) 2008-06-26
NO335196B1 (no) 2014-10-20
HK1080751A1 (en) 2006-05-04
DK1545553T3 (da) 2011-09-12
TWI332007B (en) 2010-10-21
AR040717A1 (es) 2005-04-20
EP1545553B1 (de) 2011-07-13
PT1545553E (pt) 2011-09-12
KR101066804B1 (ko) 2011-09-22
US8389497B2 (en) 2013-03-05
NO20051040L (no) 2005-02-25
CN1671397A (zh) 2005-09-21
ATE516036T1 (de) 2011-07-15
HRP20050184A2 (en) 2005-04-30
US20100189784A1 (en) 2010-07-29
IL166329A (en) 2012-08-30
TW200404073A (en) 2004-03-16
US8551977B2 (en) 2013-10-08
AU2008203060A1 (en) 2008-07-31
MXPA05001203A (es) 2005-06-08
KR20050026028A (ko) 2005-03-14
AU2003253350A1 (en) 2004-02-23
WO2004012744A1 (de) 2004-02-12
KR20110102485A (ko) 2011-09-16
CA2493023A1 (en) 2004-02-12
EP2301551A1 (de) 2011-03-30
US20040097470A1 (en) 2004-05-20
IL166329A0 (en) 2006-01-15
CN1302780C (zh) 2007-03-07
ES2369535T3 (es) 2011-12-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: AETERNA ZENTARIS GMBH (DE)

Free format text: NOME ALTERADO DE : ZENTARIS GMBH.

B25G Requested change of headquarter approved

Owner name: AETERNA ZENTARIS GMBH (DE)

Free format text: ENDERECO ALTERADO CONFORME PET NO 020060058923 - RJ DE 27/04/2006.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]

Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2317 DE 02-06-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.