NO20022599L - Klorofyll- og bakterioklorofyllestere, deres fremstilling og farmasöytiske sammensetninger som innbefatter slike - Google Patents

Klorofyll- og bakterioklorofyllestere, deres fremstilling og farmasöytiske sammensetninger som innbefatter slike

Info

Publication number
NO20022599L
NO20022599L NO20022599A NO20022599A NO20022599L NO 20022599 L NO20022599 L NO 20022599L NO 20022599 A NO20022599 A NO 20022599A NO 20022599 A NO20022599 A NO 20022599A NO 20022599 L NO20022599 L NO 20022599L
Authority
NO
Norway
Prior art keywords
sub
sup
coxr
chlorophyll
bacteriochlorophyll
Prior art date
Application number
NO20022599A
Other languages
English (en)
Other versions
NO20022599D0 (no
NO323208B1 (no
Inventor
Hugo Scheer
Nina Kammhuber
Avigdor Scherz
Alexander Brandis
Yoram Salomon
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO20022599D0 publication Critical patent/NO20022599D0/no
Publication of NO20022599L publication Critical patent/NO20022599L/no
Publication of NO323208B1 publication Critical patent/NO323208B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
NO20022599A 1999-12-01 2002-05-31 Omforestringsfremgangsmate for fremstilling av klorofyll- og bakterioklorofyll-C13(3), C-17(3) diestere NO323208B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13325399A IL133253A0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
PCT/IL2000/000811 WO2001040232A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, and their preparation

Publications (3)

Publication Number Publication Date
NO20022599D0 NO20022599D0 (no) 2002-05-31
NO20022599L true NO20022599L (no) 2002-07-11
NO323208B1 NO323208B1 (no) 2007-01-22

Family

ID=11073554

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022599A NO323208B1 (no) 1999-12-01 2002-05-31 Omforestringsfremgangsmate for fremstilling av klorofyll- og bakterioklorofyll-C13(3), C-17(3) diestere

Country Status (19)

Country Link
US (1) US7169753B2 (no)
EP (1) EP1246826B1 (no)
JP (1) JP2003515538A (no)
CN (1) CN1222526C (no)
AT (1) ATE308545T1 (no)
AU (1) AU777761B2 (no)
BR (1) BR0016051A (no)
CA (1) CA2392989A1 (no)
DE (1) DE60023748T2 (no)
DK (1) DK1246826T3 (no)
ES (1) ES2250214T3 (no)
HK (1) HK1056557A1 (no)
HU (1) HU224553B1 (no)
IL (1) IL133253A0 (no)
MX (1) MXPA02005455A (no)
NO (1) NO323208B1 (no)
PL (1) PL356391A1 (no)
RU (1) RU2250905C2 (no)
WO (1) WO2001040232A1 (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
WO2002013820A1 (en) * 2000-08-11 2002-02-21 Ceramoptec Industries, Inc. Photosensitizing ointment
AU2003230164B2 (en) 2002-05-08 2008-05-01 Yeda Research And Development Co. Ltd. Sensitized online BOLD-MRI imaging method
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
ES2572976T3 (es) 2003-07-31 2016-06-03 Gentlewaves Llc Sistema y método para el tratamiento fotodinámico de la piel
CA2437638A1 (en) 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
CA2457214A1 (en) 2004-02-06 2005-08-06 Qlt Inc. Photodynamic therapy for the treatment of acne
EP2322173B1 (en) * 2004-06-07 2016-08-10 Yeda Research And Development Co., Ltd. Cationic bacteriochlorophyll derivatives and uses thereof
CA2568744A1 (en) 2004-06-09 2005-12-22 Qlt Inc. Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied hydrophobic green porphyrins
US20090036952A1 (en) 2007-07-30 2009-02-05 National Yang-Ming University Induction driven light module and use thereof
FR2924021B1 (fr) * 2007-11-27 2010-08-13 Du Vernet Michele Eymard Composition pour le traitement de la peau par therapie photodynamique
US20110040170A1 (en) * 2008-01-28 2011-02-17 Yeda Research And Development Co., Ltd. Endoscopic imaging photodynamic therapy system and methods of use
AU2009219682B2 (en) 2008-02-27 2015-06-18 Yeda Research & Development Co. Ltd RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors
AU2012205410A1 (en) 2011-01-13 2013-08-01 Qlt Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
HUE053321T2 (hu) * 2011-08-23 2021-06-28 Yeda Res & Dev (Bakterio)klorofill fotoszenzitizátorok szembetegségek és rendellenességek kezelésére
EP2872178A1 (en) 2012-07-11 2015-05-20 Dermira, Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
US10117942B2 (en) 2013-07-12 2018-11-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery
AU2017250732B2 (en) * 2016-04-10 2022-11-10 Memorial Sloan-Kettering Cancer Center Combinational therapies for treatment of cancer comprising a bacteriochlorophyll derivative
CN108341827A (zh) * 2018-02-02 2018-07-31 浙江海正药业股份有限公司 一种制备脱镁细菌叶绿素a及脱镁细菌叶绿素a酯的方法
CN108191877A (zh) * 2018-02-05 2018-06-22 云南瑞宝生物科技股份有限公司 一种从蚕沙中提取和纯化叶绿素的方法
CN111171030B (zh) * 2018-11-12 2022-11-22 浙江海正药业股份有限公司 细菌叶绿素衍生物及其制备方法
CN111848656B (zh) * 2020-06-24 2023-03-14 天津大学 离子修饰的原卟啉镓化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
DE4121876A1 (de) * 1991-07-02 1993-01-14 Scheer Hugo Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
DE4121867A1 (de) 1991-07-02 1993-01-07 Leifeld & Lemke Maschf Vorrichtung zur pruefung der dichtigkeit von mit deckeln luftdicht verschlossenen bechern
IL102645A (en) 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
IL116126A0 (en) * 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
HUP0204167A3 (en) 2004-08-30
WO2001040232A9 (en) 2002-09-12
DE60023748T2 (de) 2006-08-03
NO20022599D0 (no) 2002-05-31
HK1056557A1 (en) 2004-02-20
NO323208B1 (no) 2007-01-22
DK1246826T3 (da) 2006-01-02
MXPA02005455A (es) 2002-11-29
IL133253A0 (en) 2001-04-30
ATE308545T1 (de) 2005-11-15
DE60023748D1 (de) 2005-12-08
HU224553B1 (hu) 2005-10-28
HUP0204167A2 (hu) 2003-03-28
ES2250214T3 (es) 2006-04-16
EP1246826B1 (en) 2005-11-02
AU1729201A (en) 2001-06-12
WO2001040232A1 (en) 2001-06-07
JP2003515538A (ja) 2003-05-07
BR0016051A (pt) 2002-07-23
PL356391A1 (en) 2004-06-28
CN1222526C (zh) 2005-10-12
US7169753B2 (en) 2007-01-30
US20030148926A1 (en) 2003-08-07
AU777761B2 (en) 2004-10-28
EP1246826A1 (en) 2002-10-09
RU2250905C2 (ru) 2005-04-27
CA2392989A1 (en) 2001-06-07
CN1425015A (zh) 2003-06-18

Similar Documents

Publication Publication Date Title
NO20022599D0 (no) Klorofyll- og bakterioklorofyllesteres, deres fremstilling og farmasöytiske sammensetninger som innbefatter slike
CY1121447T1 (el) Συνθεσεις για αυξηση δραστηριοτητας τελομερασης
WO2000040269A3 (en) Pharmaceutical compositions for treatment of diseased tissues
GEP20022804B (en) Erythropoietin Derivatives
BR9507506A (pt) Processo para exterminar uma célula processo para tratamento de càncer composição e kit terapéutico
CA2293470A1 (en) Benzimidazole derivatives
DK0619370T3 (da) Anvendelse af keratinocytvækstfaktor (KGF) til fremstilling af farmaceutiske sammensætninger
RU2007129266A (ru) Фармацевтический состав для профилактики рака и для борьбы с ним
DK1007566T3 (da) Terapeutisk anvendelse af SMR1-protein og aktive derivater deraf
RU95110937A (ru) Хинолоновые и акридиноновые соединения, способ их получения, фармацевтическая композиция и промежуточные соединения
ATE426402T1 (de) Medizinische zusammensetzungen enthaltend 2-amino-2-a2-(4-octylphenyl)ethylupropan-1,3-di l
WO1994006449A3 (en) Morphogen-induced liver regeneration
CA2392168A1 (fr) Analogues de la vitamine d
DK1165102T3 (da) Matrixproteinpræparater til podning i ikke-mineraliseret væv
PT941110E (pt) Utilizacao do factor 2 de crescimento dos ceratinocitos
EA200500661A1 (ru) Катионный аналог кардиолипина (варианты), его применение (варианты), композиция и набор для трансфекции клеток (варианты)
DK0588477T3 (da) Medicinsk præparat omfatende TCF-11
AU2002333535A1 (en) Treatment of excessive radiation (e.g. sunburn) exposure
NO995692D0 (no) Nye BPC-peptidsalter med organbeskyttende aktivitet, metoden for deres fremstilling og deres anvendelse
EP1361905B8 (en) Matrix protein compositions for guided connective tissue growth
CY1108761T1 (el) Απενεργοποιημενες κυτοκινες για ανοσοποιηση
FI972121A0 (fi) Sammansaettningar foer reciprok oekning av immunosupperssanters och interferoners farmaceutiska aktiviteter
EP1595879A3 (en) Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
EP1921451A3 (en) Complement mediated assays for in vivo and in vitro methods
UA82062C2 (uk) Фармацевтична композиція місцевого застосування для лікування захворювань, викликаних внутрішньоклітинними інфекційними агентами