IL133253A0 - Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them - Google Patents

Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL133253A0
IL133253A0 IL13325399A IL13325399A IL133253A0 IL 133253 A0 IL133253 A0 IL 133253A0 IL 13325399 A IL13325399 A IL 13325399A IL 13325399 A IL13325399 A IL 13325399A IL 133253 A0 IL133253 A0 IL 133253A0
Authority
IL
Israel
Prior art keywords
sub
sup
coxr
chlorophyll
bacteriochlorophyll
Prior art date
Application number
IL13325399A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL13325399A priority Critical patent/IL133253A0/xx
Priority to MXPA02005455A priority patent/MXPA02005455A/es
Priority to AU17292/01A priority patent/AU777761B2/en
Priority to PL00356391A priority patent/PL356391A1/xx
Priority to CA002392989A priority patent/CA2392989A1/en
Priority to ES00979916T priority patent/ES2250214T3/es
Priority to JP2001540987A priority patent/JP2003515538A/ja
Priority to AT00979916T priority patent/ATE308545T1/de
Priority to US10/148,552 priority patent/US7169753B2/en
Priority to DE60023748T priority patent/DE60023748T2/de
Priority to DK00979916T priority patent/DK1246826T3/da
Priority to CNB008186030A priority patent/CN1222526C/zh
Priority to PCT/IL2000/000811 priority patent/WO2001040232A1/en
Priority to HU0204167A priority patent/HU224553B1/hu
Priority to EP00979916A priority patent/EP1246826B1/en
Priority to BR0016051-2A priority patent/BR0016051A/pt
Priority to RU2002117287/04A priority patent/RU2250905C2/ru
Priority to IL14987500A priority patent/IL149875A0/xx
Publication of IL133253A0 publication Critical patent/IL133253A0/xx
Priority to NO20022599A priority patent/NO323208B1/no
Priority to US10/414,007 priority patent/US7045117B2/en
Priority to HK03108847A priority patent/HK1056557A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
IL13325399A 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them IL133253A0 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IL13325399A IL133253A0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
DE60023748T DE60023748T2 (de) 1999-12-01 2000-12-01 Chlorophyll- und bacteriochlorophyllester, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
PCT/IL2000/000811 WO2001040232A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, and their preparation
PL00356391A PL356391A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
CA002392989A CA2392989A1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
ES00979916T ES2250214T3 (es) 1999-12-01 2000-12-01 Esteres de clorofila y bacterioclorofila, su preparacion y composiciones farmaceuticas que los comprenden.
JP2001540987A JP2003515538A (ja) 1999-12-01 2000-12-01 クロロフィル及びバクテリオクロロフィルのエステル類、その調製及びそれを含む医薬組成物
AT00979916T ATE308545T1 (de) 1999-12-01 2000-12-01 Chlorophyll- und bacteriochlorophyllester, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
US10/148,552 US7169753B2 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
MXPA02005455A MXPA02005455A (es) 1999-12-01 2000-12-01 Esteres de clorofila y bacterioclorofila, su preparacion y composiciones farmaceuticas que los contienen.
DK00979916T DK1246826T3 (da) 1999-12-01 2000-12-01 Chlorophyl- og bakteriochlorophylestere, deres fremstilling og farmaceutiske præparater omfattende disse estere
CNB008186030A CN1222526C (zh) 1999-12-01 2000-12-01 制备合成的叶绿素或细菌叶绿素衍生物的酯交换的方法
AU17292/01A AU777761B2 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
HU0204167A HU224553B1 (hu) 1999-12-01 2000-12-01 Átészterezési eljárás klorofill- és bakterioklorofill C-133, C-173 diészterek előállítására
EP00979916A EP1246826B1 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
BR0016051-2A BR0016051A (pt) 1999-12-01 2000-12-01 ésteres clorofìlicos e bacterioclorofìlicos, sua preparação e composições farmacêuticas que os compreendem
RU2002117287/04A RU2250905C2 (ru) 1999-12-01 2000-12-01 Способ трансэтерификации для получения синтетического производного хлорофилла или бактериохлорофилла
IL14987500A IL149875A0 (en) 1999-12-01 2000-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
NO20022599A NO323208B1 (no) 1999-12-01 2002-05-31 Omforestringsfremgangsmate for fremstilling av klorofyll- og bakterioklorofyll-C13(3), C-17(3) diestere
US10/414,007 US7045117B2 (en) 1999-12-01 2003-04-16 Method for tumor diagnosis comprising administering of palladium-substituted bacteriochlorophyll derivatives
HK03108847A HK1056557A1 (en) 1999-12-01 2003-12-04 Transesterification process for preparation of synthetic chlorophyll and bacteriochlorophyll derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13325399A IL133253A0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Publications (1)

Publication Number Publication Date
IL133253A0 true IL133253A0 (en) 2001-04-30

Family

ID=11073554

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13325399A IL133253A0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
US (1) US7169753B2 (xx)
EP (1) EP1246826B1 (xx)
JP (1) JP2003515538A (xx)
CN (1) CN1222526C (xx)
AT (1) ATE308545T1 (xx)
AU (1) AU777761B2 (xx)
BR (1) BR0016051A (xx)
CA (1) CA2392989A1 (xx)
DE (1) DE60023748T2 (xx)
DK (1) DK1246826T3 (xx)
ES (1) ES2250214T3 (xx)
HK (1) HK1056557A1 (xx)
HU (1) HU224553B1 (xx)
IL (1) IL133253A0 (xx)
MX (1) MXPA02005455A (xx)
NO (1) NO323208B1 (xx)
PL (1) PL356391A1 (xx)
RU (1) RU2250905C2 (xx)
WO (1) WO2001040232A1 (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
WO2002013820A1 (en) * 2000-08-11 2002-02-21 Ceramoptec Industries, Inc. Photosensitizing ointment
JP2005524461A (ja) 2002-05-08 2005-08-18 イエダ リサーチ アンド デベロップメント カンパニー リミテッド 増感オンラインｂｏｌｄ−ｍｒｉイメージング法
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
CA2533129A1 (en) 2003-07-31 2005-02-10 Light Bioscience, Llc System and method for the photodynamic treatment of burns, wounds, and related skin disorders
CA2437638A1 (en) 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
CA2457214A1 (en) 2004-02-06 2005-08-06 Qlt Inc. Photodynamic therapy for the treatment of acne
HUE030586T2 (en) * 2004-06-07 2017-06-28 Yeda Res & Dev Cationic bacteriochlorophyll derivatives and their uses
BRPI0511897A (pt) 2004-06-09 2008-01-15 Quadra Logic Tech Inc método para tratar distúrbios de glándula sebácea hiperativa, e, uso de uma composição fotossensibilizadora hidrofóbica e/ou lipofìlica
US20090036952A1 (en) 2007-07-30 2009-02-05 National Yang-Ming University Induction driven light module and use thereof
FR2924021B1 (fr) * 2007-11-27 2010-08-13 Du Vernet Michele Eymard Composition pour le traitement de la peau par therapie photodynamique
EP2244787A1 (en) * 2008-01-28 2010-11-03 Yeda Research And Development Company Ltd. Endoscopic imaging photodynamic therapy system and methods of use
EP2257309B1 (en) 2008-02-27 2019-10-16 Yeda Research And Development Company Ltd. Rgd-(bacterio)chlorophyll conjugates for use in diagnosis of tumors comprising necrotic domains
WO2012097264A2 (en) 2011-01-13 2012-07-19 Qlt Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
PT2747763T (pt) * 2011-08-23 2021-02-22 Yeda Res & Dev Fotossensibilizadores de (bacterio)clorofila para o tratamento de doenças e distúrbios oculares
WO2014011875A1 (en) 2012-07-11 2014-01-16 Dermira, Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
US10117942B2 (en) 2013-07-12 2018-11-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery
RU2021110230A (ru) 2016-04-10 2021-05-26 Йеда Рисерч Энд Дивелопмент Ко. Лтд. Комбинированные способы терапии для лечения злокачественной опухоли
CN108341827A (zh) * 2018-02-02 2018-07-31 浙江海正药业股份有限公司 一种制备脱镁细菌叶绿素a及脱镁细菌叶绿素a酯的方法
CN108191877A (zh) * 2018-02-05 2018-06-22 云南瑞宝生物科技股份有限公司 一种从蚕沙中提取和纯化叶绿素的方法
CN111171030B (zh) * 2018-11-12 2022-11-22 浙江海正药业股份有限公司 细菌叶绿素衍生物及其制备方法
CN111848656B (zh) * 2020-06-24 2023-03-14 天津大学 离子修饰的原卟啉镓化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
DE4121876A1 (de) * 1991-07-02 1993-01-14 Scheer Hugo Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
DE4121867A1 (de) 1991-07-02 1993-01-07 Leifeld & Lemke Maschf Vorrichtung zur pruefung der dichtigkeit von mit deckeln luftdicht verschlossenen bechern
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
IL116126A0 (en) * 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
DE60023748D1 (de) 2005-12-08
ES2250214T3 (es) 2006-04-16
HUP0204167A3 (en) 2004-08-30
CN1222526C (zh) 2005-10-12
CA2392989A1 (en) 2001-06-07
RU2250905C2 (ru) 2005-04-27
HUP0204167A2 (hu) 2003-03-28
NO20022599D0 (no) 2002-05-31
DK1246826T3 (da) 2006-01-02
US7169753B2 (en) 2007-01-30
US20030148926A1 (en) 2003-08-07
CN1425015A (zh) 2003-06-18
WO2001040232A1 (en) 2001-06-07
AU1729201A (en) 2001-06-12
NO323208B1 (no) 2007-01-22
BR0016051A (pt) 2002-07-23
EP1246826A1 (en) 2002-10-09
ATE308545T1 (de) 2005-11-15
WO2001040232A9 (en) 2002-09-12
EP1246826B1 (en) 2005-11-02
NO20022599L (no) 2002-07-11
JP2003515538A (ja) 2003-05-07
PL356391A1 (en) 2004-06-28
HU224553B1 (hu) 2005-10-28
HK1056557A1 (en) 2004-02-20
MXPA02005455A (es) 2002-11-29
DE60023748T2 (de) 2006-08-03
AU777761B2 (en) 2004-10-28

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