DK1246826T3 - Chlorophyl- og bakteriochlorophylestere, deres fremstilling og farmaceutiske præparater omfattende disse estere - Google Patents

Chlorophyl- og bakteriochlorophylestere, deres fremstilling og farmaceutiske præparater omfattende disse estere

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Publication number
DK1246826T3
DK1246826T3 DK00979916T DK00979916T DK1246826T3 DK 1246826 T3 DK1246826 T3 DK 1246826T3 DK 00979916 T DK00979916 T DK 00979916T DK 00979916 T DK00979916 T DK 00979916T DK 1246826 T3 DK1246826 T3 DK 1246826T3
Authority
DK
Denmark
Prior art keywords
sub
sup
esters
coxr
chlorophyll
Prior art date
Application number
DK00979916T
Other languages
English (en)
Inventor
Avigdor Scherz
Alexander Brandis
Yoram Salomon
Hugo Scheer
Nina Kammhuber
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of DK1246826T3 publication Critical patent/DK1246826T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
DK00979916T 1999-12-01 2000-12-01 Chlorophyl- og bakteriochlorophylestere, deres fremstilling og farmaceutiske præparater omfattende disse estere DK1246826T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13325399A IL133253A0 (en) 1999-12-01 1999-12-01 Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them

Publications (1)

Publication Number Publication Date
DK1246826T3 true DK1246826T3 (da) 2006-01-02

Family

ID=11073554

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00979916T DK1246826T3 (da) 1999-12-01 2000-12-01 Chlorophyl- og bakteriochlorophylestere, deres fremstilling og farmaceutiske præparater omfattende disse estere

Country Status (19)

Country Link
US (1) US7169753B2 (da)
EP (1) EP1246826B1 (da)
JP (1) JP2003515538A (da)
CN (1) CN1222526C (da)
AT (1) ATE308545T1 (da)
AU (1) AU777761B2 (da)
BR (1) BR0016051A (da)
CA (1) CA2392989A1 (da)
DE (1) DE60023748T2 (da)
DK (1) DK1246826T3 (da)
ES (1) ES2250214T3 (da)
HK (1) HK1056557A1 (da)
HU (1) HU224553B1 (da)
IL (1) IL133253A0 (da)
MX (1) MXPA02005455A (da)
NO (1) NO323208B1 (da)
PL (1) PL356391A1 (da)
RU (1) RU2250905C2 (da)
WO (1) WO2001040232A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
EP1318807A4 (en) * 2000-08-11 2008-02-20 Ceramoptec Gmbh LIGHT-SENSITIVE OINTMENT
EP2401962A1 (en) 2002-05-08 2012-01-04 Yeda Research And Development Co., Ltd. Sensitized online BOLD-MRI imaging method
IL152900A0 (en) 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
ES2572976T3 (es) 2003-07-31 2016-06-03 Gentlewaves Llc Sistema y método para el tratamiento fotodinámico de la piel
CA2437638A1 (en) 2003-08-20 2005-02-20 John Robert North Photodynamic therapy
CA2457214A1 (en) 2004-02-06 2005-08-06 Qlt Inc. Photodynamic therapy for the treatment of acne
MXPA06014326A (es) * 2004-06-07 2007-02-19 Yeda Res & Dev Derivados de bacterioclorofila cationica y sus usos.
EP1755676B1 (en) 2004-06-09 2012-11-28 QLT, Inc. Photodynamic therapy for the treatment of hyperactive sebaceous gland disorders using topically applied verteporfin and/or lemuteporfin
US20090036952A1 (en) 2007-07-30 2009-02-05 National Yang-Ming University Induction driven light module and use thereof
FR2924021B1 (fr) * 2007-11-27 2010-08-13 Du Vernet Michele Eymard Composition pour le traitement de la peau par therapie photodynamique
CN101925382A (zh) * 2008-01-28 2010-12-22 耶达研究及发展有限公司 内窥镜成像光动力学治疗系统及其使用方法
BRPI0907791A2 (pt) 2008-02-27 2015-08-04 Yeda Res & Dev Conjugados rgd-(bacterio)clorofila para terapia fotodinâmica e formação de imagem de tumores necróticos
JP5964322B2 (ja) 2011-01-13 2016-08-03 キュー エル ティー インク.QLT Inc. 光増感剤の局所送達用医薬組成物及びその使用
JP6215203B2 (ja) * 2011-08-23 2017-10-18 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドYeda Research And Development Co. Ltd 眼疾患および障害の治療用の(バクテリオ)クロロフィル光増感剤
AU2013290140A1 (en) 2012-07-11 2015-01-29 Dermira, Inc. Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
WO2015006429A1 (en) 2013-07-12 2015-01-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery
CA3020067A1 (en) * 2016-04-10 2017-10-19 Yeda Research And Development Co. Ltd. Combinational therapies for treatment of cancer comprising a bacteriochlorophyll derivative
CN108341827A (zh) * 2018-02-02 2018-07-31 浙江海正药业股份有限公司 一种制备脱镁细菌叶绿素a及脱镁细菌叶绿素a酯的方法
CN108191877A (zh) * 2018-02-05 2018-06-22 云南瑞宝生物科技股份有限公司 一种从蚕沙中提取和纯化叶绿素的方法
CN111171030B (zh) * 2018-11-12 2022-11-22 浙江海正药业股份有限公司 细菌叶绿素衍生物及其制备方法
CN111848656B (zh) * 2020-06-24 2023-03-14 天津大学 离子修饰的原卟啉镓化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
DE4121867A1 (de) 1991-07-02 1993-01-07 Leifeld & Lemke Maschf Vorrichtung zur pruefung der dichtigkeit von mit deckeln luftdicht verschlossenen bechern
DE4121876A1 (de) * 1991-07-02 1993-01-14 Scheer Hugo Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
IL116126A0 (en) * 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
NO323208B1 (no) 2007-01-22
AU777761B2 (en) 2004-10-28
HUP0204167A3 (en) 2004-08-30
PL356391A1 (en) 2004-06-28
BR0016051A (pt) 2002-07-23
CA2392989A1 (en) 2001-06-07
AU1729201A (en) 2001-06-12
HK1056557A1 (en) 2004-02-20
DE60023748D1 (de) 2005-12-08
JP2003515538A (ja) 2003-05-07
EP1246826A1 (en) 2002-10-09
EP1246826B1 (en) 2005-11-02
WO2001040232A1 (en) 2001-06-07
HUP0204167A2 (hu) 2003-03-28
CN1425015A (zh) 2003-06-18
ES2250214T3 (es) 2006-04-16
US20030148926A1 (en) 2003-08-07
ATE308545T1 (de) 2005-11-15
MXPA02005455A (es) 2002-11-29
NO20022599L (no) 2002-07-11
IL133253A0 (en) 2001-04-30
NO20022599D0 (no) 2002-05-31
HU224553B1 (hu) 2005-10-28
WO2001040232A9 (en) 2002-09-12
DE60023748T2 (de) 2006-08-03
RU2250905C2 (ru) 2005-04-27
US7169753B2 (en) 2007-01-30
CN1222526C (zh) 2005-10-12

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