AR032758A1 - Sales valsartan, un proceso para su fabricacion, composiciones farmaceuticas y el uso de dichas sales para la preparacion de medicamentos - Google Patents

Sales valsartan, un proceso para su fabricacion, composiciones farmaceuticas y el uso de dichas sales para la preparacion de medicamentos

Info

Publication number
AR032758A1
AR032758A1 ARP010103417A ARP010103417A AR032758A1 AR 032758 A1 AR032758 A1 AR 032758A1 AR P010103417 A ARP010103417 A AR P010103417A AR P010103417 A ARP010103417 A AR P010103417A AR 032758 A1 AR032758 A1 AR 032758A1
Authority
AR
Argentina
Prior art keywords
salt
sales
bis
valsartan
preparation
Prior art date
Application number
ARP010103417A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8169294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR032758(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR032758A1 publication Critical patent/AR032758A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una sal de valsartan porque es seleccionada a partir del grupo que consiste en la sal monosodica, la sal monopotásica, la sal disodica, la sal dipotásica, la sal magnésica, la sal cálcica, la sal de bis-dietilamonio, la sal de bis-dipropilamonio, la sal de bis-dibutilamonio, la sal de mono-L-arginina, la sal de bis-L-arginina, la sal de mono-L-lisina, y la sal de bis-L-lisina, así como mezclas de sal de las mismas, un proceso para su fabricacion, composiciones farmacéuticas y el uso de dichas sales para la preparacion de medicamentos.
ARP010103417A 2000-07-19 2001-07-17 Sales valsartan, un proceso para su fabricacion, composiciones farmaceuticas y el uso de dichas sales para la preparacion de medicamentos AR032758A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00115556 2000-07-19

Publications (1)

Publication Number Publication Date
AR032758A1 true AR032758A1 (es) 2003-11-26

Family

ID=8169294

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP010103417A AR032758A1 (es) 2000-07-19 2001-07-17 Sales valsartan, un proceso para su fabricacion, composiciones farmaceuticas y el uso de dichas sales para la preparacion de medicamentos
ARP080105034A AR069374A2 (es) 2000-07-19 2008-11-19 Sales de valsartan, proceso para su fabricacion, composiciones farmaceuticas y uso de dichas sales para la preparacion de medicamentos para el tratamiento de enfermedades mediadas por el bloqueo del receptor at1.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP080105034A AR069374A2 (es) 2000-07-19 2008-11-19 Sales de valsartan, proceso para su fabricacion, composiciones farmaceuticas y uso de dichas sales para la preparacion de medicamentos para el tratamiento de enfermedades mediadas por el bloqueo del receptor at1.

Country Status (31)

Country Link
US (5) US20030207930A1 (es)
EP (1) EP1313714B1 (es)
JP (1) JP4102664B2 (es)
KR (1) KR100529658B1 (es)
CN (2) CN100413852C (es)
AR (2) AR032758A1 (es)
AT (1) ATE406355T1 (es)
AU (2) AU2001289672B2 (es)
BR (1) BR0112665A (es)
CA (1) CA2415962C (es)
CY (1) CY1108559T1 (es)
CZ (1) CZ303389B6 (es)
DE (1) DE60135560D1 (es)
DK (1) DK1313714T3 (es)
EC (1) ECSP034436A (es)
ES (1) ES2309090T3 (es)
HK (1) HK1055963A1 (es)
HU (1) HU229280B1 (es)
IL (2) IL153882A0 (es)
MX (1) MXPA03000525A (es)
MY (2) MY136446A (es)
NO (1) NO326504B1 (es)
NZ (1) NZ523557A (es)
PE (1) PE20020613A1 (es)
PL (1) PL205715B1 (es)
PT (1) PT1313714E (es)
RU (1) RU2275363C2 (es)
SI (1) SI1313714T1 (es)
SK (1) SK287558B6 (es)
WO (1) WO2002006253A1 (es)
ZA (1) ZA200300285B (es)

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JP4102664B2 (ja) 2000-07-19 2008-06-18 ノバルティス アクチエンゲゼルシャフト バルサルタン塩
MXPA04006917A (es) * 2002-01-17 2004-12-06 Novartis Ag Composiciones farmaceuticas que comprenden inhibidores de valsartan y endopeptidasa neutra.
US7468390B2 (en) 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
US6869970B2 (en) * 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
WO2003089417A1 (en) * 2002-04-15 2003-10-30 Dr. Reddy's Laboratories Limited Novel crystalline forms of (s)-n-(1-carboxy-2-methyl-prop-1-yl) -n-pentanoyl-n- [2’-(1h-tetrazol-5-yl-)- biphenyl-4-yl methyl] amine (valsartan)
EG24716A (en) 2002-05-17 2010-06-07 Novartis Ag Combination of organic compounds
MXPA04011428A (es) * 2002-05-17 2005-02-14 Novartis Ag Combinacion de bloqueador del receptor de angiotensina ii y bloqueador-beta para la prevencion secundaria de infarto de miocardio.
DE60323835D1 (de) * 2002-06-13 2008-11-13 Novartis Ag Calciumsalze von statinen aus indol
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
US7199144B2 (en) 2003-04-21 2007-04-03 Teva Pharmaceuticals Industries, Ltd. Process for the preparation of valsartan and intermediates thereof
WO2004083192A1 (en) * 2003-03-17 2004-09-30 Teva Pharmaceutical Industries Ltd. Polymorphis of valsartan
EP1950204A1 (en) 2003-03-17 2008-07-30 Teva Pharmaceutical Industries Ltd. Amorphous form of valsartan
AU2003223106A1 (en) * 2003-03-31 2004-10-25 Hetero Drugs Limited A novel amorphous form of valsartan
WO2004094392A1 (en) * 2003-04-21 2004-11-04 Teva Pharmaceutical Industries Ltd. Process for the preparation of valsartan
WO2005049587A1 (en) * 2003-11-21 2005-06-02 Ranbaxy Laboratories Limited Process for preparation of biphenyl tetrazole
WO2006002983A1 (en) * 2004-07-06 2006-01-12 Novartis Ag Combination of organic compounds
EP1674080A1 (en) * 2004-12-24 2006-06-28 KRKA, D.D., Novo Mesto Solid pharmaceutical composition comprising valsartan
AU2005318365B2 (en) * 2004-12-24 2011-02-03 Krka, D.D., Novo Mesto Solid pharmaceutical composition comprising valsartan
GB0503062D0 (en) * 2005-02-14 2005-03-23 Novartis Ag Combination of organic compounds
EP1896433A4 (en) * 2005-05-25 2010-06-02 Ipca Lab Ltd NOVEL CRYSTALLINE FORMS OF (S) -N- (1-CARBOXY-2-METHYL-PROP-1-YL) -N-PENTANOYL-N- [2 '- (1H-TETRAZOL-5-YL) BI-PHENYL-4 ylmethyl] amine
FR2886642B1 (fr) * 2005-06-06 2008-05-30 Sanofi Aventis Sa Sels alcalino-terreux d'irbesartan et leur preparation
WO2007045663A2 (en) * 2005-10-19 2007-04-26 Novartis Ag Combination of an ati receptor antagonist and a np inhibitor fro treating ia hypertension and heartfailure
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
RU2459809C2 (ru) * 2005-11-09 2012-08-27 Новартис Аг Фармацевтические комбинации антагониста рецептора ангиотензина и ингибитора nep
WO2007071750A1 (en) * 2005-12-22 2007-06-28 Enantia, S.L. Intermediates and processes for the preparation of valsartan
EP2043607A2 (en) * 2006-06-23 2009-04-08 Usv Limited Process for the preparation of micronized valsartan
WO2008018843A1 (en) * 2006-08-08 2008-02-14 Ulkar Kimya Sanayi Ve Ticaret As Process for producing useful salts form of biphenyl-tetrazole compounds
US20080152717A1 (en) * 2006-12-14 2008-06-26 Isp Investments, Inc. Amorphous valsartan and the production thereof
JP2010526126A (ja) * 2007-05-07 2010-07-29 シプラ・リミテッド バルサルタンの製造方法
ES2312162T3 (es) * 2007-06-07 2009-02-16 Inke, S.A. Procedimiento para la obtencion de una sal de valsartan util para la preparacion de valsartan.
MX2010003668A (es) * 2007-10-05 2010-07-02 S Bio Pte Ltd Derivados de purina sustituidas con primidina.
PT2295035T (pt) 2007-11-06 2016-08-22 Novartis Ag Composições farmacêuticas de dupla acção com base em superestruturas de antagonista/bloqueador de receptores de angiotensina (arb) com inibidor da endopeptidase neutra (nep)
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RU2013109365A (ru) 2010-08-03 2014-09-10 Новартис Аг Высококристаллический валсартан
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WO2017042700A1 (en) * 2015-09-07 2017-03-16 Sun Pharmaceutical Industries Limited Solid forms of valsartan and sacubitril
CN105541741A (zh) * 2016-01-14 2016-05-04 青岛友诚高新技术有限公司 一种具有治疗冠心病活性的化合物及其制备方法
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CN106243056A (zh) * 2016-07-29 2016-12-21 陈欣怡 一种缬沙坦的新型固体形式
WO2018040065A1 (zh) * 2016-09-02 2018-03-08 诺瑞特国际药业股份有限公司 缬沙坦二钠盐的晶型
TWI648267B (zh) * 2016-09-02 2019-01-21 諾瑞特國際藥業股份有限公司 纈沙坦二鈉鹽新晶型
WO2018078592A1 (en) 2016-10-28 2018-05-03 Biocon Limited Amorphous trisodium sacubitril valsartan and process for its preparation
WO2018178295A1 (en) 2017-03-31 2018-10-04 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Stable hot-melt extrudate containing valsartan and sacubitril
US11382866B2 (en) * 2017-07-06 2022-07-12 Mankind Pharma Ltd. Fixed dose pharmaceutical composition of valsartan and sacubitril
WO2019020706A1 (en) 2017-07-28 2019-01-31 Synthon B.V. PHARMACEUTICAL COMPOSITION COMPRISING SACUBITRIL AND VALSARTAN
EP3694493A1 (en) 2017-10-13 2020-08-19 Alfred E. Tiefenbacher (GmbH & Co. KG) Tablet containing valsartan and sacubitril
EP3498698A1 (en) 2017-12-15 2019-06-19 Mankind Pharma Ltd Solid forms of valsartan disodium and process of preparation thereof
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Also Published As

Publication number Publication date
US9499499B2 (en) 2016-11-22
CZ2003117A3 (cs) 2003-05-14
US20070149587A1 (en) 2007-06-28
PL205715B1 (pl) 2010-05-31
MY152846A (en) 2014-11-28
US20120329844A1 (en) 2012-12-27
DE60135560D1 (de) 2008-10-09
NO326504B1 (no) 2008-12-15
NO20030232L (no) 2003-01-17
NO20030232D0 (no) 2003-01-17
CA2415962A1 (en) 2002-01-24
CY1108559T1 (el) 2014-04-09
PT1313714E (pt) 2008-11-03
CN1680341A (zh) 2005-10-12
JP2004504307A (ja) 2004-02-12
EP1313714A1 (en) 2003-05-28
MY136446A (en) 2008-10-31
IL153882A (en) 2009-09-01
IL153882A0 (en) 2003-07-31
MXPA03000525A (es) 2003-05-14
SK552003A3 (en) 2003-07-01
HU229280B1 (en) 2013-10-28
WO2002006253A1 (en) 2002-01-24
BR0112665A (pt) 2003-06-24
CN1443176A (zh) 2003-09-17
ES2309090T3 (es) 2008-12-16
EP1313714B1 (en) 2008-08-27
HUP0300731A2 (hu) 2003-09-29
CN1216873C (zh) 2005-08-31
ATE406355T1 (de) 2008-09-15
CN100413852C (zh) 2008-08-27
CA2415962C (en) 2010-07-06
US8278339B2 (en) 2012-10-02
ZA200300285B (en) 2004-03-25
DK1313714T3 (da) 2008-12-15
NZ523557A (en) 2004-12-24
CZ303389B6 (cs) 2012-08-29
US20080293791A1 (en) 2008-11-27
AU8967201A (en) 2002-01-30
JP4102664B2 (ja) 2008-06-18
HUP0300731A3 (en) 2006-05-29
RU2275363C2 (ru) 2006-04-27
HK1055963A1 (en) 2004-01-30
KR20030015888A (ko) 2003-02-25
US20030207930A1 (en) 2003-11-06
AU2001289672B2 (en) 2005-12-08
PL360737A1 (en) 2004-09-20
SK287558B6 (sk) 2011-02-04
PE20020613A1 (es) 2002-08-07
ECSP034436A (es) 2003-03-10
AR069374A2 (es) 2010-01-20
US20140073677A1 (en) 2014-03-13
SI1313714T1 (sl) 2009-02-28
KR100529658B1 (ko) 2005-11-21

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