AR032641A1 - Agonista de subtipo de receptor 5-ht 1a. - Google Patents

Agonista de subtipo de receptor 5-ht 1a.

Info

Publication number
AR032641A1
AR032641A1 ARP020100118A ARP020100118A AR032641A1 AR 032641 A1 AR032641 A1 AR 032641A1 AR P020100118 A ARP020100118 A AR P020100118A AR P020100118 A ARP020100118 A AR P020100118A AR 032641 A1 AR032641 A1 AR 032641A1
Authority
AR
Argentina
Prior art keywords
subtipe
agonist
receiver
carbon
bond
Prior art date
Application number
ARP020100118A
Other languages
English (en)
Spanish (es)
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25087808&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR032641(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of AR032641A1 publication Critical patent/AR032641A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ARP020100118A 2001-01-29 2002-01-15 Agonista de subtipo de receptor 5-ht 1a. AR032641A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77021001A 2001-01-29 2001-01-29

Publications (1)

Publication Number Publication Date
AR032641A1 true AR032641A1 (es) 2003-11-19

Family

ID=25087808

Family Applications (4)

Application Number Title Priority Date Filing Date
ARP020100118A AR032641A1 (es) 2001-01-29 2002-01-15 Agonista de subtipo de receptor 5-ht 1a.
ARP100104973A AR079761A2 (es) 2001-01-29 2010-12-28 Agonista de subtipo de receptor 5-ht1a
ARP110101189A AR080849A2 (es) 2001-01-29 2011-04-08 Uso de una composicion farmaceutica de un compuesto de carboestirilo
ARP150100766A AR099754A2 (es) 2001-01-29 2015-03-13 Composición farmacéutica agonista de subtipo de receptor 5-ht₁a

Family Applications After (3)

Application Number Title Priority Date Filing Date
ARP100104973A AR079761A2 (es) 2001-01-29 2010-12-28 Agonista de subtipo de receptor 5-ht1a
ARP110101189A AR080849A2 (es) 2001-01-29 2011-04-08 Uso de una composicion farmaceutica de un compuesto de carboestirilo
ARP150100766A AR099754A2 (es) 2001-01-29 2015-03-13 Composición farmacéutica agonista de subtipo de receptor 5-ht₁a

Country Status (19)

Country Link
EP (3) EP1355639B1 (enExample)
JP (4) JP4178032B2 (enExample)
KR (5) KR100653591B1 (enExample)
CN (3) CN1239154C (enExample)
AR (4) AR032641A1 (enExample)
AT (3) ATE504293T1 (enExample)
AU (4) AU2002226752C1 (enExample)
BR (1) BR0206237A (enExample)
CA (2) CA2429496C (enExample)
CY (3) CY1105631T1 (enExample)
DE (3) DE60220325T2 (enExample)
DK (3) DK1355639T3 (enExample)
ES (3) ES2363366T3 (enExample)
MX (2) MX344556B (enExample)
MY (1) MY129355A (enExample)
PH (1) PH12014500937A1 (enExample)
PT (3) PT1621198E (enExample)
TW (2) TWI302832B (enExample)
WO (1) WO2002060423A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR032641A1 (es) * 2001-01-29 2003-11-19 Otsuka Pharma Co Ltd Agonista de subtipo de receptor 5-ht 1a.
US7053092B2 (en) 2001-01-29 2006-05-30 Otsuka Pharmaceutical Co., Ltd. 5-HT1a receptor subtype agonist
US8703772B2 (en) 2001-09-25 2014-04-22 Otsuka Pharmaceutical Co., Ltd. Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
DE10148233A1 (de) * 2001-09-28 2003-04-10 Boehringer Ingelheim Pharma Verbindungen zur Reduzierung übermäßiger Nahrungsaufnahme
MXPA05000294A (es) * 2002-07-30 2005-08-19 Peter Migaly Terapia combinada para la depresion, prevencion de suicidios y varias condiciones medicas y psiquiatricas.
AU2003295235B2 (en) 2002-12-27 2008-06-19 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and serotonin reuptake inhibitors for treatment of mood disorders
AR042806A1 (es) 2002-12-27 2005-07-06 Otsuka Pharma Co Ltd Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo
CN102166359A (zh) * 2003-05-23 2011-08-31 大塚制药株式会社 用于治疗情感障碍的喹诺酮衍生物和情绪稳定剂
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
FR2865650B1 (fr) * 2004-01-30 2008-06-13 Biocortech Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil
WO2006090273A2 (en) * 2005-02-22 2006-08-31 Warner-Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds with keto or hydroxyl linkers for the treatment of schizophrenia
EP1912650B8 (en) * 2005-08-03 2017-10-18 Sprout Pharmaceuticals, Inc. Use of flibanserin in the treatment of obesity
TW200848041A (en) 2007-03-30 2008-12-16 Otsuka Pharma Co Ltd A medicament for treating schizophrenia comprising cilostazol
GB2456183A (en) 2008-01-04 2009-07-08 Gw Pharma Ltd Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament
JP2009286740A (ja) * 2008-05-30 2009-12-10 Otsuka Pharmaceut Co Ltd アリピプラゾールを含有する逆耐性抑制剤
EP2338873A1 (en) 2009-12-22 2011-06-29 Gmeiner, Peter New aminotetraline derivatives
TW201343201A (zh) 2012-03-06 2013-11-01 Otsuka Pharma Co Ltd 持續釋放型口服固體製劑
JOP20200109A1 (ar) 2012-04-23 2017-06-16 Otsuka Pharma Co Ltd مستحضر قابل للحقن

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS5646812A (en) * 1979-09-27 1981-04-28 Otsuka Pharmaceut Co Ltd Central nervous system depressant
DE3721799C2 (de) 1986-07-01 1993-12-23 Mitsubishi Electric Corp Integrierte Redox-Bauelementschaltung und Verfahren zum Herstellen
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JP2608788B2 (ja) * 1988-10-31 1997-05-14 大塚製薬 株式会社 精神分裂病治療剤
EP0586525B1 (en) * 1991-05-20 1997-04-16 PHARMACIA & UPJOHN COMPANY Carboxamido-(1,2n)-carbocyclic-2-aminotetralin derivatives
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
WO1994009765A1 (en) * 1992-10-23 1994-05-11 New York University Functional interactions between glial s-100b and central nervous system serotonergic neurons
DK148292D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Forbindelser
JP2959615B2 (ja) * 1993-06-24 1999-10-06 吉富製薬株式会社 縮合型チオフェン化合物およびその医薬用途
JPH09291034A (ja) * 1996-02-27 1997-11-11 Yoshitomi Pharmaceut Ind Ltd 縮合ピリジン化合物およびその医薬としての用途
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
US6110918A (en) * 1996-05-07 2000-08-29 Pfizer Inc Mesylate trihydrate salt of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihy dro-2(1H)-indol-2-one (=ziprasidone), its preparation and its use as dopamine D2 antagonist
JP4012994B2 (ja) * 1996-05-08 2007-11-28 大塚製薬株式会社 抗不安薬
AU4091697A (en) * 1996-08-27 1998-03-19 American Home Products Corporation 4-aminoethoxy indoles as dopamin d2 agonists and as 5ht1a ligands
EP1053235A1 (en) * 1998-02-03 2000-11-22 American Home Products Corporation Oxazole derivatives as serotonin-1a receptor agonists
WO1999052870A1 (en) * 1998-04-13 1999-10-21 American Home Products Corporation 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists
JPH11335286A (ja) * 1998-05-25 1999-12-07 Mitsui Chem Inc ドーパミン拮抗薬の効果増強剤
AR032641A1 (es) * 2001-01-29 2003-11-19 Otsuka Pharma Co Ltd Agonista de subtipo de receptor 5-ht 1a.
DE60234873D1 (de) * 2001-06-19 2010-02-04 Norbert Mueller Verwendung von COX-2 Inhibitoren zur Behandlung von affectiven Störungen
AR033485A1 (es) * 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma

Also Published As

Publication number Publication date
DK1621198T3 (da) 2007-09-24
PT1621198E (pt) 2007-06-08
ATE362763T1 (de) 2007-06-15
CA2429496C (en) 2010-10-19
EP1621198A3 (en) 2006-04-12
EP1712225A1 (en) 2006-10-18
ES2363366T3 (es) 2011-08-02
AU2009233591A1 (en) 2009-11-19
CN1239154C (zh) 2006-02-01
CA2429496A1 (en) 2002-08-08
DK1355639T3 (da) 2006-08-14
DE60220325D1 (de) 2007-07-05
DE60210581T2 (de) 2007-04-05
PT1355639E (pt) 2006-06-30
KR100713607B1 (ko) 2007-05-02
KR100825705B1 (ko) 2008-04-29
AU2007201701B2 (en) 2010-06-17
MY129355A (en) 2007-03-30
KR20060085260A (ko) 2006-07-26
KR100601073B1 (ko) 2006-07-19
WO2002060423A3 (en) 2003-04-10
JP4896831B2 (ja) 2012-03-14
BR0206237A (pt) 2003-12-23
PT1712225E (pt) 2011-04-18
CN100450485C (zh) 2009-01-14
CA2700314C (en) 2012-04-24
JP2004517937A (ja) 2004-06-17
HK1061805A1 (en) 2004-10-08
CN1879624A (zh) 2006-12-20
AU2002226752B2 (en) 2005-03-17
EP1355639A2 (en) 2003-10-29
EP1712225B1 (en) 2011-04-06
AU2005201772A1 (en) 2005-05-19
ES2286755T3 (es) 2007-12-01
AU2002226752C1 (en) 2010-02-18
MXPA03006603A (es) 2004-02-12
EP1621198A2 (en) 2006-02-01
ATE504293T1 (de) 2011-04-15
JP5683010B2 (ja) 2015-03-11
JP4178032B2 (ja) 2008-11-12
AU2005201772C1 (en) 2010-06-03
AR079761A2 (es) 2012-02-15
AU2009233591B2 (en) 2011-10-20
WO2002060423A2 (en) 2002-08-08
DE60210581D1 (en) 2006-05-24
HK1091403A1 (zh) 2007-01-19
EP1355639B1 (en) 2006-04-12
PH12014500937A1 (en) 2015-09-21
JP2007297405A (ja) 2007-11-15
CN1813745A (zh) 2006-08-09
DK1712225T3 (da) 2011-06-20
KR20030065570A (ko) 2003-08-06
DE60239711D1 (de) 2011-05-19
CY1105631T1 (el) 2010-12-22
CY1111392T1 (el) 2015-08-05
EP1621198B1 (en) 2007-05-23
JP2011184460A (ja) 2011-09-22
DE60220325T2 (de) 2008-01-17
AU2005201772B2 (en) 2007-05-17
KR100763288B1 (ko) 2007-10-04
AU2007201701A1 (en) 2007-05-10
CA2700314A1 (en) 2002-08-08
KR20070065425A (ko) 2007-06-22
KR20050107822A (ko) 2005-11-15
MX344556B (es) 2016-12-20
KR20060028485A (ko) 2006-03-29
TW200522960A (en) 2005-07-16
CN1484524A (zh) 2004-03-24
ATE322894T1 (de) 2006-04-15
KR100653591B1 (ko) 2006-12-05
TWI302832B (en) 2008-11-11
AR080849A2 (es) 2012-05-09
AR099754A2 (es) 2016-08-17
CY1108031T1 (el) 2013-09-04
JP2011225587A (ja) 2011-11-10
TWI331919B (en) 2010-10-21
ES2261652T3 (es) 2006-11-16

Similar Documents

Publication Publication Date Title
AR032641A1 (es) Agonista de subtipo de receptor 5-ht 1a.
ATE459357T1 (de) Kombinationen zur behandlung von multiplem myelom
GT200000019A (es) Inhibidores de la recaptacion de monoaminas para el tratamiento de trastornos del snc.
EP2178870A4 (en) INDOL AND INDAZONE COMPOUNDS AS AN INHIBITORS OF CELL NECROSIS
WO2005013892A3 (en) Hydrolytically-resistant boron-containing therapeutics and methods of use
ATE466014T1 (de) Spiroazacyclische verbindungen als monoaminrezeptormodulatoren
ATE482209T1 (de) Verbindungen und zusammensetzungen als modulatoren der gpr119-aktivität
MA31158B1 (fr) Composes tricycliques et leur utilisation comme modulateurs du recepteur de glucocorticoïdes
PT1543011E (pt) Composto de tienopirrolilo e furanopirrolilo e sua utilizacao como ligandos do receptor h4 da histamina
NO20082011L (no) Acylerte spiropiperidinderivater som melanocortin-4-reseptormodulatorer
UY33020A (es) INHIBIDORES DE N1-PIRAZOLOESPIROCETONA ACETIL-CoA CARBOXILASA
MXPA05002942A (es) Forma de dosificacion oral de liberacion modificada.
CY1107747T1 (el) Υποκατεστημενα τετρακυκλικα παραγωγα πυρρολοκινολονης χρησιμα ως αναστολεις της φωσφοδιεστερασης
UA103930C2 (ru) Соединения и композиция для лечения паразитарных болезней
MX2010003948A (es) N-fenil-birrolidin ureas sustituidas y uso terapeutico de las mismas.
EA200700909A1 (ru) Азаиндолкарбоксамиды
TW200736229A (en) Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
MY124786A (en) Bis-arylsulfones
NO20054494L (no) Peptidvektorer
GT200400041A (es) Derivados azabiciclicos de piridiloximetilo y bencisoxazol
WO2001091796A8 (en) Methods, compounds and compositions for treating gout
GT199700096A (es) Ligandos espirociclos de un subtipo de receptor de la dopamina.
UA106200C2 (uk) Заміщені похідні оксіндолу та їхнє застосування для лікування захворювань, залежних від вазопресину
UA74430C2 (uk) Похідні фенілгетероциклічних етерів як інгібітори зворотного захоплення серотоніну
PA8567701A1 (es) Agonistas del receptor b3-adrenergico

Legal Events

Date Code Title Description
FC Refusal