KR100653591B1 - 5-ｈｔ1ａ 수용체 서브타입 작용물질 - Google Patents
5-ｈｔ1ａ 수용체 서브타입 작용물질 Download PDFInfo
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- KR100653591B1 KR100653591B1 KR1020057019896A KR20057019896A KR100653591B1 KR 100653591 B1 KR100653591 B1 KR 100653591B1 KR 1020057019896 A KR1020057019896 A KR 1020057019896A KR 20057019896 A KR20057019896 A KR 20057019896A KR 100653591 B1 KR100653591 B1 KR 100653591B1
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- cognitive impairment
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Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Otolaryngology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77021001A | 2001-01-29 | 2001-01-29 | |
| US09/770,210 | 2001-01-29 | ||
| PCT/JP2002/000626 WO2002060423A2 (en) | 2001-01-29 | 2002-01-29 | Substituted carbostyril derivatives as 5-ht1a receptor subtype agonists |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020037008565A Division KR100601073B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020067014046A Division KR100713607B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
Publications (2)
| Publication Number | Publication Date |
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| KR20050107822A KR20050107822A (ko) | 2005-11-15 |
| KR100653591B1 true KR100653591B1 (ko) | 2006-12-05 |
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| KR1020067005164A Ceased KR100763288B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
| KR1020037008565A Expired - Lifetime KR100601073B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
| KR1020077010561A Expired - Lifetime KR100825705B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
| KR1020067014046A Expired - Lifetime KR100713607B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
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| KR1020067005164A Ceased KR100763288B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
| KR1020037008565A Expired - Lifetime KR100601073B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
| KR1020077010561A Expired - Lifetime KR100825705B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
| KR1020067014046A Expired - Lifetime KR100713607B1 (ko) | 2001-01-29 | 2002-01-29 | 5-ｈｔ1ａ 수용체 서브타입 작용물질 |
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|---|---|
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| JP (4) | JP4178032B2 (enExample) |
| KR (5) | KR100653591B1 (enExample) |
| CN (3) | CN1239154C (enExample) |
| AR (4) | AR032641A1 (enExample) |
| AT (3) | ATE504293T1 (enExample) |
| AU (4) | AU2002226752C1 (enExample) |
| BR (1) | BR0206237A (enExample) |
| CA (2) | CA2429496C (enExample) |
| CY (3) | CY1105631T1 (enExample) |
| DE (3) | DE60220325T2 (enExample) |
| DK (3) | DK1355639T3 (enExample) |
| ES (3) | ES2363366T3 (enExample) |
| MX (2) | MX344556B (enExample) |
| MY (1) | MY129355A (enExample) |
| PH (1) | PH12014500937A1 (enExample) |
| PT (3) | PT1621198E (enExample) |
| TW (2) | TWI302832B (enExample) |
| WO (1) | WO2002060423A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR032641A1 (es) * | 2001-01-29 | 2003-11-19 | Otsuka Pharma Co Ltd | Agonista de subtipo de receptor 5-ht 1a. |
| US7053092B2 (en) | 2001-01-29 | 2006-05-30 | Otsuka Pharmaceutical Co., Ltd. | 5-HT1a receptor subtype agonist |
| US8703772B2 (en) | 2001-09-25 | 2014-04-22 | Otsuka Pharmaceutical Co., Ltd. | Low hygroscopic aripiprazole drug substance and processes for the preparation thereof |
| AR033485A1 (es) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
| DE10148233A1 (de) * | 2001-09-28 | 2003-04-10 | Boehringer Ingelheim Pharma | Verbindungen zur Reduzierung übermäßiger Nahrungsaufnahme |
| MXPA05000294A (es) * | 2002-07-30 | 2005-08-19 | Peter Migaly | Terapia combinada para la depresion, prevencion de suicidios y varias condiciones medicas y psiquiatricas. |
| AU2003295235B2 (en) | 2002-12-27 | 2008-06-19 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and serotonin reuptake inhibitors for treatment of mood disorders |
| AR042806A1 (es) | 2002-12-27 | 2005-07-06 | Otsuka Pharma Co Ltd | Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo |
| CN102166359A (zh) * | 2003-05-23 | 2011-08-31 | 大塚制药株式会社 | 用于治疗情感障碍的喹诺酮衍生物和情绪稳定剂 |
| US7160888B2 (en) | 2003-08-22 | 2007-01-09 | Warner Lambert Company Llc | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia |
| FR2865650B1 (fr) * | 2004-01-30 | 2008-06-13 | Biocortech | Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil |
| WO2006090273A2 (en) * | 2005-02-22 | 2006-08-31 | Warner-Lambert Company Llc | [1,8]naphthyridin-2-ones and related compounds with keto or hydroxyl linkers for the treatment of schizophrenia |
| EP1912650B8 (en) * | 2005-08-03 | 2017-10-18 | Sprout Pharmaceuticals, Inc. | Use of flibanserin in the treatment of obesity |
| TW200848041A (en) | 2007-03-30 | 2008-12-16 | Otsuka Pharma Co Ltd | A medicament for treating schizophrenia comprising cilostazol |
| GB2456183A (en) | 2008-01-04 | 2009-07-08 | Gw Pharma Ltd | Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament |
| JP2009286740A (ja) * | 2008-05-30 | 2009-12-10 | Otsuka Pharmaceut Co Ltd | アリピプラゾールを含有する逆耐性抑制剤 |
| EP2338873A1 (en) | 2009-12-22 | 2011-06-29 | Gmeiner, Peter | New aminotetraline derivatives |
| TW201343201A (zh) | 2012-03-06 | 2013-11-01 | Otsuka Pharma Co Ltd | 持續釋放型口服固體製劑 |
| JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPS5646812A (en) * | 1979-09-27 | 1981-04-28 | Otsuka Pharmaceut Co Ltd | Central nervous system depressant |
| DE3721799C2 (de) | 1986-07-01 | 1993-12-23 | Mitsubishi Electric Corp | Integrierte Redox-Bauelementschaltung und Verfahren zum Herstellen |
| US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JP2608788B2 (ja) * | 1988-10-31 | 1997-05-14 | 大塚製薬 株式会社 | 精神分裂病治療剤 |
| EP0586525B1 (en) * | 1991-05-20 | 1997-04-16 | PHARMACIA & UPJOHN COMPANY | Carboxamido-(1,2n)-carbocyclic-2-aminotetralin derivatives |
| US5532240A (en) * | 1991-12-26 | 1996-07-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Condensed thiophene compound and pharmaceutical use thereof |
| WO1994009765A1 (en) * | 1992-10-23 | 1994-05-11 | New York University | Functional interactions between glial s-100b and central nervous system serotonergic neurons |
| DK148292D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Forbindelser |
| JP2959615B2 (ja) * | 1993-06-24 | 1999-10-06 | 吉富製薬株式会社 | 縮合型チオフェン化合物およびその医薬用途 |
| JPH09291034A (ja) * | 1996-02-27 | 1997-11-11 | Yoshitomi Pharmaceut Ind Ltd | 縮合ピリジン化合物およびその医薬としての用途 |
| US5688950A (en) * | 1996-04-23 | 1997-11-18 | Neurogen Corporation | Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands |
| US6110918A (en) * | 1996-05-07 | 2000-08-29 | Pfizer Inc | Mesylate trihydrate salt of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihy dro-2(1H)-indol-2-one (=ziprasidone), its preparation and its use as dopamine D2 antagonist |
| JP4012994B2 (ja) * | 1996-05-08 | 2007-11-28 | 大塚製薬株式会社 | 抗不安薬 |
| AU4091697A (en) * | 1996-08-27 | 1998-03-19 | American Home Products Corporation | 4-aminoethoxy indoles as dopamin d2 agonists and as 5ht1a ligands |
| EP1053235A1 (en) * | 1998-02-03 | 2000-11-22 | American Home Products Corporation | Oxazole derivatives as serotonin-1a receptor agonists |
| WO1999052870A1 (en) * | 1998-04-13 | 1999-10-21 | American Home Products Corporation | 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists |
| JPH11335286A (ja) * | 1998-05-25 | 1999-12-07 | Mitsui Chem Inc | ドーパミン拮抗薬の効果増強剤 |
| AR032641A1 (es) * | 2001-01-29 | 2003-11-19 | Otsuka Pharma Co Ltd | Agonista de subtipo de receptor 5-ht 1a. |
| DE60234873D1 (de) * | 2001-06-19 | 2010-02-04 | Norbert Mueller | Verwendung von COX-2 Inhibitoren zur Behandlung von affectiven Störungen |
| AR033485A1 (es) * | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
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2002
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- 2002-01-25 TW TW091101289A patent/TWI302832B/zh not_active IP Right Cessation
- 2002-01-25 TW TW093127321A patent/TWI331919B/zh not_active IP Right Cessation
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- 2002-01-29 ES ES06015782T patent/ES2363366T3/es not_active Expired - Lifetime
- 2002-01-29 AT AT06015782T patent/ATE504293T1/de active
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- 2002-01-29 JP JP2002560616A patent/JP4178032B2/ja not_active Expired - Lifetime
- 2002-01-29 MX MX2011010975A patent/MX344556B/es unknown
- 2002-01-29 DE DE60220325T patent/DE60220325T2/de not_active Expired - Lifetime
- 2002-01-29 CN CNB028035518A patent/CN1239154C/zh not_active Expired - Lifetime
- 2002-01-29 EP EP02716434A patent/EP1355639B1/en not_active Expired - Lifetime
- 2002-01-29 ES ES02716434T patent/ES2261652T3/es not_active Expired - Lifetime
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- 2002-01-29 KR KR1020057019896A patent/KR100653591B1/ko not_active Expired - Lifetime
- 2002-01-29 PT PT05023971T patent/PT1621198E/pt unknown
- 2002-01-29 KR KR1020067005164A patent/KR100763288B1/ko not_active Ceased
- 2002-01-29 KR KR1020037008565A patent/KR100601073B1/ko not_active Expired - Lifetime
- 2002-01-29 AT AT05023971T patent/ATE362763T1/de active
- 2002-01-29 CN CNB2005100228288A patent/CN100450485C/zh not_active Expired - Lifetime
- 2002-01-29 EP EP06015782A patent/EP1712225B1/en not_active Revoked
- 2002-01-29 CN CNA2006100943881A patent/CN1879624A/zh active Pending
- 2002-01-29 MX MXPA03006603A patent/MXPA03006603A/es active IP Right Grant
- 2002-01-29 ES ES05023971T patent/ES2286755T3/es not_active Expired - Lifetime
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- 2002-01-29 WO PCT/JP2002/000626 patent/WO2002060423A2/en not_active Ceased
- 2002-01-29 EP EP05023971A patent/EP1621198B1/en not_active Revoked
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2005
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2006
- 2006-06-28 CY CY20061100884T patent/CY1105631T1/el unknown
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2007
- 2007-04-17 AU AU2007201701A patent/AU2007201701B2/en not_active Expired
- 2007-07-09 JP JP2007179275A patent/JP4896831B2/ja not_active Expired - Lifetime
- 2007-08-20 CY CY20071101093T patent/CY1108031T1/el unknown
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2009
- 2009-10-29 AU AU2009233591A patent/AU2009233591B2/en not_active Expired
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2010
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2011
- 2011-04-08 AR ARP110101189A patent/AR080849A2/es not_active Application Discontinuation
- 2011-04-18 CY CY20111100391T patent/CY1111392T1/el unknown
- 2011-06-15 JP JP2011133032A patent/JP5683010B2/ja not_active Expired - Lifetime
- 2011-06-15 JP JP2011133033A patent/JP2011184460A/ja active Pending
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2014
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2015
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