AR022575A1 - Inmunoglobulina humanizada que reacciona con moleculas b7 y metodos de tratamiento con la misma - Google Patents

Inmunoglobulina humanizada que reacciona con moleculas b7 y metodos de tratamiento con la misma

Info

Publication number
AR022575A1
AR022575A1 ARP000100602A ARP000100602A AR022575A1 AR 022575 A1 AR022575 A1 AR 022575A1 AR P000100602 A ARP000100602 A AR P000100602A AR P000100602 A ARP000100602 A AR P000100602A AR 022575 A1 AR022575 A1 AR 022575A1
Authority
AR
Argentina
Prior art keywords
treatment methods
reacts
molecules
same
humanized immunoglobulin
Prior art date
Application number
ARP000100602A
Other languages
English (en)
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of AR022575A1 publication Critical patent/AR022575A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Anticuerpos humanizados anti-B7-2 y anti-B7-1, donde cada uno contiene una region variable de origen no humano y al menos una porcion de unainmunoglobulina de origen humano. La invencion se relaciona también con métodos de tratamiento para variasenf ermedades autoinmunes, rechazo de trasplantes,trastornos inflamatorios y enfermedades infecciosas, administrando los anticuerpos humanizados anti-B7-2 y/o anti B7-1.
ARP000100602A 1999-02-12 2000-02-11 Inmunoglobulina humanizada que reacciona con moleculas b7 y metodos de tratamiento con la misma AR022575A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/249,011 US6972125B2 (en) 1999-02-12 1999-02-12 Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith
US09/339,596 US6913747B1 (en) 1999-02-12 1999-06-24 Humanized immunoglobulin reactive with B7 therewith

Publications (1)

Publication Number Publication Date
AR022575A1 true AR022575A1 (es) 2002-09-04

Family

ID=22941666

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000100602A AR022575A1 (es) 1999-02-12 2000-02-11 Inmunoglobulina humanizada que reacciona con moleculas b7 y metodos de tratamiento con la misma

Country Status (6)

Country Link
US (5) US6972125B2 (es)
KR (1) KR20020002389A (es)
AR (1) AR022575A1 (es)
EA (1) EA200100892A1 (es)
HK (1) HK1042708A1 (es)
ZA (1) ZA200106982B (es)

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Also Published As

Publication number Publication date
ZA200106982B (en) 2002-12-11
US20020176855A1 (en) 2002-11-28
EA200100892A1 (ru) 2002-02-28
US7666421B2 (en) 2010-02-23
US6972125B2 (en) 2005-12-06
KR20020002389A (ko) 2002-01-09
US6913747B1 (en) 2005-07-05
US6827934B1 (en) 2004-12-07
US6984383B1 (en) 2006-01-10
US20060251645A1 (en) 2006-11-09
HK1042708A1 (zh) 2002-08-23

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