HK1042708A1 - 人類免疫球蛋白對b7分子的反應和利用其治療的方法 - Google Patents

人類免疫球蛋白對b7分子的反應和利用其治療的方法

Info

Publication number
HK1042708A1
HK1042708A1 HK02101392.0A HK02101392A HK1042708A1 HK 1042708 A1 HK1042708 A1 HK 1042708A1 HK 02101392 A HK02101392 A HK 02101392A HK 1042708 A1 HK1042708 A1 HK 1042708A1
Authority
HK
Hong Kong
Prior art keywords
molecules
methods
humanized immunoglobulin
treatment therewith
immunoglobulin reactive
Prior art date
Application number
HK02101392.0A
Other languages
English (en)
Inventor
Sung Co Man
Vasquez Maximiliano
Carreno Beatriz
Cheryl Celniker Abbie
Collins Mary
Goldman Samuel
S Gray Gary
Knight Andrea
O'hara Denise
Rup Bonita
M Veldman Geertruida
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/003303 external-priority patent/WO2000047625A2/en
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Publication of HK1042708A1 publication Critical patent/HK1042708A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK02101392.0A 1999-02-12 2002-02-22 人類免疫球蛋白對b7分子的反應和利用其治療的方法 HK1042708A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/249,011 US6972125B2 (en) 1999-02-12 1999-02-12 Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith
US09/339,596 US6913747B1 (en) 1999-02-12 1999-06-24 Humanized immunoglobulin reactive with B7 therewith
PCT/US2000/003303 WO2000047625A2 (en) 1999-02-12 2000-02-09 Humanized immunoglobulin reactive with b7 molecules and methods of treatment therewith

Publications (1)

Publication Number Publication Date
HK1042708A1 true HK1042708A1 (zh) 2002-08-23

Family

ID=22941666

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02101392.0A HK1042708A1 (zh) 1999-02-12 2002-02-22 人類免疫球蛋白對b7分子的反應和利用其治療的方法

Country Status (6)

Country Link
US (5) US6972125B2 (zh)
KR (1) KR20020002389A (zh)
AR (1) AR022575A1 (zh)
EA (1) EA200100892A1 (zh)
HK (1) HK1042708A1 (zh)
ZA (1) ZA200106982B (zh)

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Also Published As

Publication number Publication date
US6913747B1 (en) 2005-07-05
US7666421B2 (en) 2010-02-23
KR20020002389A (ko) 2002-01-09
ZA200106982B (en) 2002-12-11
AR022575A1 (es) 2002-09-04
US6972125B2 (en) 2005-12-06
US20020176855A1 (en) 2002-11-28
EA200100892A1 (ru) 2002-02-28
US6984383B1 (en) 2006-01-10
US6827934B1 (en) 2004-12-07
US20060251645A1 (en) 2006-11-09

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