AR021468A1 - Preparacion de esteres esterolicos y estanolicos - Google Patents

Preparacion de esteres esterolicos y estanolicos

Info

Publication number
AR021468A1
AR021468A1 ARP990104240A ARP990104240A AR021468A1 AR 021468 A1 AR021468 A1 AR 021468A1 AR P990104240 A ARP990104240 A AR P990104240A AR P990104240 A ARP990104240 A AR P990104240A AR 021468 A1 AR021468 A1 AR 021468A1
Authority
AR
Argentina
Prior art keywords
esterolicos
estanolicos
esteres
preparation
esters
Prior art date
Application number
ARP990104240A
Other languages
English (en)
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/336,773 external-priority patent/US6184397B1/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of AR021468A1 publication Critical patent/AR021468A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invencion provee un método para la esterificacion directa de estanoles y esteroles con catalizador, el cual puede ser ácido o básico, enpresencia de un agente desactivador de color para formar ésteres estanolicos/esterolicos; el método provee una ruta sintética que es aplicable a la producciona gran escala de los ésteres en altos rendimientos; una modalidad preferida emplea un procedimiento grado alimenticio libre de solventes orgánicos o ácidosminerales.
ARP990104240A 1998-08-25 1999-08-25 Preparacion de esteres esterolicos y estanolicos AR021468A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/139,460 US5892068A (en) 1998-08-25 1998-08-25 Preparation of sterol and stanol-esters
US09/211,978 US6147236A (en) 1998-08-25 1998-12-15 Preparation of sterol and stanol-esters
US09/336,773 US6184397B1 (en) 1998-08-25 1999-06-21 Preparation of sterol and stanol-esters

Publications (1)

Publication Number Publication Date
AR021468A1 true AR021468A1 (es) 2002-07-24

Family

ID=22486771

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP990100262A AR017444A1 (es) 1998-08-25 1999-01-22 Un metodo para producir esteres de esterol y de estanol, dichos compuestos y el uso de los mismos para la fabricacion de un medicamento
ARP990104240A AR021468A1 (es) 1998-08-25 1999-08-25 Preparacion de esteres esterolicos y estanolicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP990100262A AR017444A1 (es) 1998-08-25 1999-01-22 Un metodo para producir esteres de esterol y de estanol, dichos compuestos y el uso de los mismos para la fabricacion de un medicamento

Country Status (7)

Country Link
US (2) US5892068A (es)
AR (2) AR017444A1 (es)
AU (1) AU764572B2 (es)
BR (1) BR9900280A (es)
HU (2) HU9900145D0 (es)
PT (1) PT982316E (es)
ZA (2) ZA99368B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0898896T3 (da) * 1997-08-22 2004-10-18 Unilever Nv Næringsmidler på grundlag af fedtstoffer indeholdende steroler
DE69818942T2 (de) * 1997-08-22 2004-09-09 Unilever N.V. Stanolester enthaltende Zusammensetzungen
EP0897970B1 (en) * 1997-08-22 2004-09-29 Unilever N.V. Process for the production of stanol esters
US6394230B1 (en) * 1997-12-16 2002-05-28 Cognis Corporation Sterol esters as food additives
US6139897A (en) * 1998-03-24 2000-10-31 Kao Corporation Oil or fat composition containing phytosterol
US5892068A (en) * 1998-08-25 1999-04-06 Mcneil-Ppc, Inc. Preparation of sterol and stanol-esters
NZ333817A (en) * 1998-08-25 2000-09-29 Mcneil Ppc Inc Process for preparing stanol/sterol fatty acid esters such as beta sitosterol fatty acid esters, useful in reducing cholesterol levels
US6277431B1 (en) * 1998-10-14 2001-08-21 Redeem, Inc. Anticholesterolemic edible oil
NZ501169A (en) * 1998-11-26 2001-05-25 F Fatty acid esters of phytosterol and phytostanol
US6410758B2 (en) * 1999-05-24 2002-06-25 Mcneil-Ppc, Inc. Preparation of sterol and stanol-esters
EP1211955A1 (en) * 1999-08-30 2002-06-12 Ocean Nutrition Canada Ltd. A nutritional supplement for lowering serum triglyceride and cholesterol levels
US6998501B1 (en) 1999-08-30 2006-02-14 Ocean Nutrition Canada Limited Nutritional supplement for lowering serum triglyceride and cholesterol levels
WO2001029060A2 (en) 1999-10-21 2001-04-26 The Board Of Regents For Oklahoma State University Sterol esters of conjugated linoleic acids and process for their production
ATE259160T1 (de) 1999-11-05 2004-02-15 Raisio Benecol Oy Essbare fettmischungen
US6391370B1 (en) * 1999-11-12 2002-05-21 Kraft Foods, Inc. Micromilling plant sterols and emulsifiers
US6355274B1 (en) 1999-12-15 2002-03-12 Mcneil-Ppc, Inc. Encapsulated long chain alcohols
US7232574B1 (en) 1999-12-15 2007-06-19 Mcneil-Ppc, Inc. Long chain alcohols provided in edible oils
AU2001253294A1 (en) 2000-04-14 2001-10-30 Mars, Incorporated Compositions and methods for improving vascular health
FR2811984B1 (fr) * 2000-07-19 2004-02-06 Pharmascience Lab Procede de preparation d'un ester de corps gras et son utilisation dans les domaines pharmaceutique, cosmetique ou alimentaire
US6576285B1 (en) * 2000-11-14 2003-06-10 Sunpure Ltd. Cholesterol lowering beverage
SE523094C2 (sv) * 2001-01-11 2004-03-30 Karlshamns Ab Förfarande för framställning av en fettkomposition som innehåller sterolestrar, fria steroler och glycerider, fettkomposition framställd genom förfarandet samt fettkompositionens användning
US20020107232A1 (en) * 2001-01-12 2002-08-08 Flickinger Brent D. Methods for producing sterol ester-rich compositions
US6787151B2 (en) * 2001-08-10 2004-09-07 Lipton, Division Of Conopco, Inc. Composition for lowering blood cholesterol
EP1285969B1 (en) * 2001-08-22 2006-10-11 Härting, Thomas Francis Process for producing sterol or stanol esters by enzymatic transesterification in solvent and water-free media
US7514107B2 (en) 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
WO2003086468A1 (en) * 2002-04-10 2003-10-23 Cargill, Incorporated Aqueous dispersible steryl ester compositions
AU2003291446A1 (en) * 2002-11-12 2004-06-03 Wiley Organics, Inc. Method for purifying and separating soy isoflavones
EP1660516A1 (en) * 2003-09-05 2006-05-31 University of Nebraska-Lincoln Compound and method for enhancing the cholesterol lowering property of plant sterol and stanol esters
CA2598792A1 (en) * 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
US20080015374A1 (en) * 2006-07-11 2008-01-17 Wiley Organics, Inc. Method for the synthesis and isolation of phytosterol esters
CN102603845B (zh) * 2012-01-21 2014-10-22 西安海斯夫生物科技有限公司 合成与分离植物甾醇饱和脂肪酸酯和不饱和脂肪酸酯的方法
CN104262444B (zh) * 2014-09-03 2016-09-14 陕西海斯夫生物工程有限公司 一种植物甾醇脂肪酸酯及其催化合成方法
CN106755252B (zh) * 2016-11-30 2019-09-17 江苏大学 一锅法制备亲水性植物甾醇/甾烷醇衍生物的方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1284814A (en) * 1918-08-02 1918-11-12 John P Sutter Reading-light.
NL6512867A (es) * 1965-10-05 1967-04-06
GB1141690A (en) * 1966-12-29 1969-01-29 Wolf Ltd Victor Cis-trans isomerisation of unsaturated fatty acids or their esters
CA928140A (en) * 1969-07-17 1973-06-12 A. Erickson Billy Clear cooking and salad oils having hypocholesterolemic properties
DE2248921C3 (de) * 1972-10-05 1981-11-12 Harburger Oelwerke Brinckman & Mergell, 2100 Hamburg Verfahren zur Herstellung eines Gemisches aus pflanzlichen und tierischen Ölen bzw. Fetten und Fettsäuresterinestern
ES414508A1 (es) * 1973-05-08 1976-02-01 Ferrer Labor Procedimiento de fabricacion de un compuesto de accion hi- polipemiante.
JPS5111113A (en) * 1974-07-18 1976-01-29 Shiro Aoki Kaitenmuranyoru enshinryokuno hensaoryoshita suishinsochi
JPS5923320B2 (ja) * 1979-10-31 1984-06-01 花王株式会社 分岐脂肪酸コレステリルエステル
US4393044A (en) * 1980-05-29 1983-07-12 The Nisshin Oil Mills Limited Steroid ester, and cosmetics and ointments containing the same
JPS5745199A (en) * 1980-09-01 1982-03-13 Nisshin Oil Mills Ltd:The Esterification product and cosmetic or external use preparation containing the same
SE8303031D0 (sv) * 1983-05-30 1983-05-30 Leo Ab Improved steroid esters preparation
GB8329316D0 (en) * 1983-11-03 1983-12-07 Inst Penyelidikan Minyak Kelap Esterification of carboxylic acids
US4588717A (en) * 1984-06-13 1986-05-13 David C. Mitchell Medical Research Institute Compounds and vitamin supplements and methods for making same
DE3445650A1 (de) * 1984-12-14 1986-06-19 Rudolf Erich Dipl.-Chem. 7760 Radolfzell Klemke Verfahren zur darstellung c(pfeil abwaerts)7(pfeil abwaerts)-hydroxylierter cholesterole und desmosterole
CH665770A5 (de) * 1985-01-25 1988-06-15 Sulzer Ag Knochenimplantat aus kunststoff.
FR2647805A1 (fr) * 1989-06-06 1990-12-07 Bugat Maurice Procede de fabrication d'esters d'acides gras, produits isoles correspondants et compositions a usage humain ou veterinaire les contenant
EP0436682B1 (de) * 1989-07-21 1994-01-19 Marigen S.A. Sterole, deren fettsäureester und glucoside; verfahren zu ihrer herstellung; spontan dispergierbare mittel mit diesen verbindungen, sowie ihre verwendung zur behandlung von tumoren
US5723747A (en) * 1991-02-22 1998-03-03 Calgene, Inc. Wax esters in transformed plants
CA2102112C (en) * 1991-05-03 2010-04-13 Tatu Miettinen A substance for lowering high cholesterol level in serum and a method for preparing the same
JP3527754B2 (ja) * 1992-04-27 2004-05-17 日本精化株式会社 ラノリン脂肪酸類の分離法及びそれらを用いた化粧料及び外用薬
CH681891A5 (es) * 1992-10-09 1993-06-15 Marigen Sa
GB9300125D0 (en) * 1993-01-06 1993-03-03 Scotia Holdings Plc Compositions containing esters of unsaturated fatty acids
WO1995000158A1 (en) * 1993-06-25 1995-01-05 Bio-Sphere Technology Dietary supplement incorporating beta-sitosterol and pectin
US5917068A (en) * 1995-12-29 1999-06-29 Eastman Chemical Company Polyunsaturated fatty acid and fatty acid ester mixtures free of sterols and phosphorus compounds
US6200624B1 (en) * 1996-01-26 2001-03-13 Abbott Laboratories Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids
DE69827330T2 (de) * 1997-08-22 2006-02-02 Unilever N.V. Stanolester enthaltende Zusammensetzung
EP0897971B1 (en) * 1997-08-22 2004-11-03 Unilever N.V. Stanol ester composition
EP0897970B1 (en) * 1997-08-22 2004-09-29 Unilever N.V. Process for the production of stanol esters
DE69818942T2 (de) * 1997-08-22 2004-09-09 Unilever N.V. Stanolester enthaltende Zusammensetzungen
US6394230B1 (en) * 1997-12-16 2002-05-28 Cognis Corporation Sterol esters as food additives
WO1999039715A1 (en) * 1998-02-06 1999-08-12 Medical Isotopes Inc. Readily absorbable phytosterols to treat hypercholesterrolemia
FI109327B (fi) * 1998-02-27 2002-07-15 Spice Sciences Oy Menetelmä seerumin kokonais- ja LDL-kolestrolipitoisuutta alentavan beta-sitosterolin rasvamaisen seoksen valmistamiseksi
US6025348A (en) * 1998-04-30 2000-02-15 Kao Corporation Oil and fat composition containing phytosterol
US5892068A (en) * 1998-08-25 1999-04-06 Mcneil-Ppc, Inc. Preparation of sterol and stanol-esters

Also Published As

Publication number Publication date
ZA99368B (en) 2000-07-19
US6147236A (en) 2000-11-14
HU9900145D0 (en) 1999-03-29
HU9900163D0 (en) 1999-03-29
HUP9900163A2 (en) 2000-07-28
AU1316699A (en) 2000-03-09
ZA995418B (en) 2001-02-20
US5892068A (en) 1999-04-06
AR017444A1 (es) 2001-09-05
HUP9900163A3 (en) 2001-10-29
AU764572B2 (en) 2003-08-21
PT982316E (pt) 2007-12-18
BR9900280A (pt) 2000-05-02

Similar Documents

Publication Publication Date Title
AR021468A1 (es) Preparacion de esteres esterolicos y estanolicos
AR029636A1 (es) Metodo para producir esteres estanolicos/esterolicos y compuestos asi obtenidos.
ES2196502T3 (es) Composicion y metodo para inhibir el desarrollo de microorganismos que incluye hipobromito sodico estabilizado e isotiazolonas.
DK0982315T3 (da) Fremstilling af sterol- og stanolestere
ES2107574T5 (es) Procedimiento para la preparacion de polisacaridos modificados y polisacaridos modificados.
BR0008675A (pt) Processo para gerar código de linguagem orientada para procedimento para extrair dados de um sistema operacional
BR9809317A (pt) Parede de sustentação para sustentar uma contenção e processo para formar a mesma
PE134199A1 (es) Inhibicion de la oxidacion de lipoproteinas
ES2056105T3 (es) Di-t-butilfenoles sustituidos.
ES2125535T5 (es) Mezclas, que contienen isocianatos emulsionables en agua.
ES2157259T3 (es) Procedimiento para preparar esteres de aminoacidos y analogos de nucleosidos.
PT1124817E (pt) Processo para preparacao de esteres de delta-9-tetra-hidrocanabinol
CO4410206A1 (es) DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
DK0982316T3 (da) Fremstilling af sterol- og stanolestere
NO20023276L (no) Fremgangsmåter fremstilling av betulinsyre
ES2156920T3 (es) Un procedimiento para la recombinacion de alimentos con gelificacion controlada.
ES2175175T3 (es) Un metodo microbiano para la 11alfa-hidroxilacion de esteroides.
ES2128396T3 (es) Composiciones de poliester-policarbonato esterilizadas.
ES2126798T3 (es) Procedimiento de preparacion de anhidrido tetrafluoroftalico.
ES2035102T3 (es) Compuestos que contienen hierro biodisponible, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
MX9303640A (es) Proceso mejorado para la produccion de anhidrido ftalico.
CR6000A (es) Un limpiador
ES2031987T3 (es) Un metodo para producir una preparacion liofilizada de un compuesto de platino.
ES2179222T3 (es) Conjugados covalentes de lipido de acido fosfono-carboxilico y su aplicacion como medicamentos antiviricos.
ES2196528T3 (es) Derivados de gemcitabina.

Legal Events

Date Code Title Description
FB Suspension of granting procedure