BR9900280A - Preparação de ésteres de esterol e estanol. - Google Patents
Preparação de ésteres de esterol e estanol.Info
- Publication number
- BR9900280A BR9900280A BR9900280-9A BR9900280A BR9900280A BR 9900280 A BR9900280 A BR 9900280A BR 9900280 A BR9900280 A BR 9900280A BR 9900280 A BR9900280 A BR 9900280A
- Authority
- BR
- Brazil
- Prior art keywords
- sterol
- esters
- preparation
- stanol
- stanol esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Patente de Invenção: <B>"PREPARAçãO DE éSTERES DE ESTEROL E ESTANOL"<D>. A presente invenção provê um método para a esterificação direta de estanóis e esteróis com ácidos graxos para formar ésteres de estanol/esterol. O método provê uma via sintética que é acessível para produção em grande escala de ésteres, com altos rendimento. Uma modalidade preferida emprega um processo de grau alimentício isento de solventes orgânicos ou ácidos minerais.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/139,460 US5892068A (en) | 1998-08-25 | 1998-08-25 | Preparation of sterol and stanol-esters |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9900280A true BR9900280A (pt) | 2000-05-02 |
Family
ID=22486771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9900280-9A BR9900280A (pt) | 1998-08-25 | 1999-02-02 | Preparação de ésteres de esterol e estanol. |
Country Status (7)
Country | Link |
---|---|
US (2) | US5892068A (pt) |
AR (2) | AR017444A1 (pt) |
AU (1) | AU764572B2 (pt) |
BR (1) | BR9900280A (pt) |
HU (2) | HU9900145D0 (pt) |
PT (1) | PT982316E (pt) |
ZA (2) | ZA99368B (pt) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2229443T3 (es) * | 1997-08-22 | 2005-04-16 | Unilever N.V. | Procedimiento para la produccion de esteres de estanol. |
EP0898896B1 (en) * | 1997-08-22 | 2004-06-16 | Unilever N.V. | Fat based food products comprising sterols |
DK0911385T3 (da) * | 1997-08-22 | 2004-02-02 | Unilever Nv | Stanolholdige sammensætninger |
US6394230B1 (en) * | 1997-12-16 | 2002-05-28 | Cognis Corporation | Sterol esters as food additives |
US6139897A (en) * | 1998-03-24 | 2000-10-31 | Kao Corporation | Oil or fat composition containing phytosterol |
NZ333817A (en) * | 1998-08-25 | 2000-09-29 | Mcneil Ppc Inc | Process for preparing stanol/sterol fatty acid esters such as beta sitosterol fatty acid esters, useful in reducing cholesterol levels |
US5892068A (en) * | 1998-08-25 | 1999-04-06 | Mcneil-Ppc, Inc. | Preparation of sterol and stanol-esters |
US6277431B1 (en) * | 1998-10-14 | 2001-08-21 | Redeem, Inc. | Anticholesterolemic edible oil |
NZ501169A (en) * | 1998-11-26 | 2001-05-25 | F | Fatty acid esters of phytosterol and phytostanol |
US6410758B2 (en) * | 1999-05-24 | 2002-06-25 | Mcneil-Ppc, Inc. | Preparation of sterol and stanol-esters |
US6998501B1 (en) | 1999-08-30 | 2006-02-14 | Ocean Nutrition Canada Limited | Nutritional supplement for lowering serum triglyceride and cholesterol levels |
WO2001015552A1 (en) * | 1999-08-30 | 2001-03-08 | Ocean Nutrition Canada Ltd. | A nutritional supplement for lowering serum triglyceride and cholesterol levels |
AU2118701A (en) | 1999-10-21 | 2001-04-30 | Board Of Regents For Oklahoma State University, The | Sterol esters of conjugated linoleic acids and process for their production |
JP4907816B2 (ja) | 1999-11-05 | 2012-04-04 | ライシオ ベネコール オサケユイチア | 食用脂配合物 |
US6391370B1 (en) * | 1999-11-12 | 2002-05-21 | Kraft Foods, Inc. | Micromilling plant sterols and emulsifiers |
US6355274B1 (en) | 1999-12-15 | 2002-03-12 | Mcneil-Ppc, Inc. | Encapsulated long chain alcohols |
US7232574B1 (en) | 1999-12-15 | 2007-06-19 | Mcneil-Ppc, Inc. | Long chain alcohols provided in edible oils |
KR20030005280A (ko) | 2000-04-14 | 2003-01-17 | 마아즈, 인코오포레이티드 | 혈관의 건강을 개선하기 위한 조성물과 방법 |
FR2811984B1 (fr) * | 2000-07-19 | 2004-02-06 | Pharmascience Lab | Procede de preparation d'un ester de corps gras et son utilisation dans les domaines pharmaceutique, cosmetique ou alimentaire |
US6576285B1 (en) * | 2000-11-14 | 2003-06-10 | Sunpure Ltd. | Cholesterol lowering beverage |
SE523094C2 (sv) * | 2001-01-11 | 2004-03-30 | Karlshamns Ab | Förfarande för framställning av en fettkomposition som innehåller sterolestrar, fria steroler och glycerider, fettkomposition framställd genom förfarandet samt fettkompositionens användning |
US20020107232A1 (en) * | 2001-01-12 | 2002-08-08 | Flickinger Brent D. | Methods for producing sterol ester-rich compositions |
US6787151B2 (en) * | 2001-08-10 | 2004-09-07 | Lipton, Division Of Conopco, Inc. | Composition for lowering blood cholesterol |
ATE342374T1 (de) * | 2001-08-22 | 2006-11-15 | Haerting Thomas Francis | Verfahren zur herstellung von sterol- und stanolestern mittels enzymatischer transesterifikation in lösungsmittel- und wasserfreien medien |
US7514107B2 (en) | 2002-03-21 | 2009-04-07 | Mars, Incorporated | Treatment of diseases involving defective gap junctional communication |
US20040013708A1 (en) * | 2002-04-10 | 2004-01-22 | Goulson Melanie J. | Aqueous dispersible steryl ester compositions |
WO2004043945A1 (en) * | 2002-11-12 | 2004-05-27 | Wiley Organics, Inc. | Method for purifying and separating soy isoflavones |
CA2537744A1 (en) * | 2003-09-05 | 2005-03-17 | Timothy P. Carr | Compound and method for enhancing the cholesterol lowering property of plant sterol and stanol esters |
CA2598792A1 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
US20080015374A1 (en) * | 2006-07-11 | 2008-01-17 | Wiley Organics, Inc. | Method for the synthesis and isolation of phytosterol esters |
CN102603845B (zh) * | 2012-01-21 | 2014-10-22 | 西安海斯夫生物科技有限公司 | 合成与分离植物甾醇饱和脂肪酸酯和不饱和脂肪酸酯的方法 |
CN104262444B (zh) * | 2014-09-03 | 2016-09-14 | 陕西海斯夫生物工程有限公司 | 一种植物甾醇脂肪酸酯及其催化合成方法 |
CN106755252B (zh) * | 2016-11-30 | 2019-09-17 | 江苏大学 | 一锅法制备亲水性植物甾醇/甾烷醇衍生物的方法 |
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US1284814A (en) * | 1918-08-02 | 1918-11-12 | John P Sutter | Reading-light. |
NL6512867A (pt) * | 1965-10-05 | 1967-04-06 | ||
GB1141690A (en) * | 1966-12-29 | 1969-01-29 | Wolf Ltd Victor | Cis-trans isomerisation of unsaturated fatty acids or their esters |
CA928140A (en) * | 1969-07-17 | 1973-06-12 | A. Erickson Billy | Clear cooking and salad oils having hypocholesterolemic properties |
DE2248921C3 (de) * | 1972-10-05 | 1981-11-12 | Harburger Oelwerke Brinckman & Mergell, 2100 Hamburg | Verfahren zur Herstellung eines Gemisches aus pflanzlichen und tierischen Ölen bzw. Fetten und Fettsäuresterinestern |
ES414508A1 (es) * | 1973-05-08 | 1976-02-01 | Ferrer Labor | Procedimiento de fabricacion de un compuesto de accion hi- polipemiante. |
JPS5111113A (en) * | 1974-07-18 | 1976-01-29 | Shiro Aoki | Kaitenmuranyoru enshinryokuno hensaoryoshita suishinsochi |
JPS5923320B2 (ja) * | 1979-10-31 | 1984-06-01 | 花王株式会社 | 分岐脂肪酸コレステリルエステル |
US4393044A (en) * | 1980-05-29 | 1983-07-12 | The Nisshin Oil Mills Limited | Steroid ester, and cosmetics and ointments containing the same |
JPS5745199A (en) * | 1980-09-01 | 1982-03-13 | Nisshin Oil Mills Ltd:The | Esterification product and cosmetic or external use preparation containing the same |
SE8303031D0 (sv) * | 1983-05-30 | 1983-05-30 | Leo Ab | Improved steroid esters preparation |
GB8329316D0 (en) * | 1983-11-03 | 1983-12-07 | Inst Penyelidikan Minyak Kelap | Esterification of carboxylic acids |
US4588717A (en) * | 1984-06-13 | 1986-05-13 | David C. Mitchell Medical Research Institute | Compounds and vitamin supplements and methods for making same |
DE3445650A1 (de) * | 1984-12-14 | 1986-06-19 | Rudolf Erich Dipl.-Chem. 7760 Radolfzell Klemke | Verfahren zur darstellung c(pfeil abwaerts)7(pfeil abwaerts)-hydroxylierter cholesterole und desmosterole |
CH665770A5 (de) * | 1985-01-25 | 1988-06-15 | Sulzer Ag | Knochenimplantat aus kunststoff. |
FR2647805A1 (fr) * | 1989-06-06 | 1990-12-07 | Bugat Maurice | Procede de fabrication d'esters d'acides gras, produits isoles correspondants et compositions a usage humain ou veterinaire les contenant |
JP2656997B2 (ja) * | 1989-07-21 | 1997-09-24 | マリゲン ソシエテ アノニム | ステロールの脂肪酸エステルの抗腫瘍剤のための自発的分散性濃縮物及びそれを含む医薬組成物 |
US5723747A (en) * | 1991-02-22 | 1998-03-03 | Calgene, Inc. | Wax esters in transformed plants |
JP2708633B2 (ja) * | 1991-05-03 | 1998-02-04 | ライシオン テータート オサケユイチア アクティエボラーグ | 血清における高コレステロールレベルを低めるための物質及びその物質を調製するための方法 |
JP3527754B2 (ja) * | 1992-04-27 | 2004-05-17 | 日本精化株式会社 | ラノリン脂肪酸類の分離法及びそれらを用いた化粧料及び外用薬 |
CH681891A5 (pt) * | 1992-10-09 | 1993-06-15 | Marigen Sa | |
GB9300125D0 (en) * | 1993-01-06 | 1993-03-03 | Scotia Holdings Plc | Compositions containing esters of unsaturated fatty acids |
AU7250694A (en) * | 1993-06-25 | 1995-01-17 | Biosphere Technologies Inc. | Dietary supplement incorporating beta-sitosterol and pectin |
US5917068A (en) * | 1995-12-29 | 1999-06-29 | Eastman Chemical Company | Polyunsaturated fatty acid and fatty acid ester mixtures free of sterols and phosphorus compounds |
US6200624B1 (en) * | 1996-01-26 | 2001-03-13 | Abbott Laboratories | Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids |
EP0897971B1 (en) * | 1997-08-22 | 2004-11-03 | Unilever N.V. | Stanol ester composition |
ES2229443T3 (es) * | 1997-08-22 | 2005-04-16 | Unilever N.V. | Procedimiento para la produccion de esteres de estanol. |
ES2231940T3 (es) * | 1997-08-22 | 2005-05-16 | Unilever N.V. | Composicion de esteres de estanol. |
DK0911385T3 (da) * | 1997-08-22 | 2004-02-02 | Unilever Nv | Stanolholdige sammensætninger |
US6394230B1 (en) * | 1997-12-16 | 2002-05-28 | Cognis Corporation | Sterol esters as food additives |
AU2660099A (en) * | 1998-02-06 | 1999-08-23 | Medical Isotopes Inc. | Readily absorbable phytosterols to treat hypercholesterrolemia |
FI109327B (fi) * | 1998-02-27 | 2002-07-15 | Spice Sciences Oy | Menetelmä seerumin kokonais- ja LDL-kolestrolipitoisuutta alentavan beta-sitosterolin rasvamaisen seoksen valmistamiseksi |
US6025348A (en) * | 1998-04-30 | 2000-02-15 | Kao Corporation | Oil and fat composition containing phytosterol |
US5892068A (en) * | 1998-08-25 | 1999-04-06 | Mcneil-Ppc, Inc. | Preparation of sterol and stanol-esters |
-
1998
- 1998-08-25 US US09/139,460 patent/US5892068A/en not_active Expired - Lifetime
- 1998-12-15 US US09/211,978 patent/US6147236A/en not_active Expired - Lifetime
-
1999
- 1999-01-19 ZA ZA9900368A patent/ZA99368B/xx unknown
- 1999-01-19 AU AU13166/99A patent/AU764572B2/en not_active Ceased
- 1999-01-19 HU HU9900145A patent/HU9900145D0/hu unknown
- 1999-01-22 AR ARP990100262A patent/AR017444A1/es unknown
- 1999-01-25 HU HU9900163A patent/HUP9900163A3/hu unknown
- 1999-02-02 BR BR9900280-9A patent/BR9900280A/pt not_active Application Discontinuation
- 1999-08-24 PT PT99306718T patent/PT982316E/pt unknown
- 1999-08-24 ZA ZA9905418A patent/ZA995418B/xx unknown
- 1999-08-25 AR ARP990104240A patent/AR021468A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
HU9900163D0 (en) | 1999-03-29 |
HUP9900163A2 (en) | 2000-07-28 |
ZA995418B (en) | 2001-02-20 |
US6147236A (en) | 2000-11-14 |
PT982316E (pt) | 2007-12-18 |
US5892068A (en) | 1999-04-06 |
HU9900145D0 (en) | 1999-03-29 |
AU1316699A (en) | 2000-03-09 |
AU764572B2 (en) | 2003-08-21 |
AR017444A1 (es) | 2001-09-05 |
ZA99368B (en) | 2000-07-19 |
AR021468A1 (es) | 2002-07-24 |
HUP9900163A3 (en) | 2001-10-29 |
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Legal Events
Date | Code | Title | Description |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM ARTIGOS 8O E 13 DA LPI. |
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B09B | Patent application refused [chapter 9.2 patent gazette] |
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