ES2031987T3 - Un metodo para producir una preparacion liofilizada de un compuesto de platino. - Google Patents
Un metodo para producir una preparacion liofilizada de un compuesto de platino.Info
- Publication number
- ES2031987T3 ES2031987T3 ES198888119857T ES88119857T ES2031987T3 ES 2031987 T3 ES2031987 T3 ES 2031987T3 ES 198888119857 T ES198888119857 T ES 198888119857T ES 88119857 T ES88119857 T ES 88119857T ES 2031987 T3 ES2031987 T3 ES 2031987T3
- Authority
- ES
- Spain
- Prior art keywords
- produce
- lyophilized preparation
- platinum compound
- preparation
- platinum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCION RELATA UNA PREPARACION LIOFILIZADA QUE COMPRENDE CIS-1, 1-CICLOBUTANODICARBOXILATO (2R)-2-METIL-1, 4 BUTANODIAMINA DE PLATINO (II), LA CUAL ES UTIL COMO DROGA ANTITUNOVAL Y DREXTRANA. ESTA PREPARACION TIENE UNA GRATA MEJORA DE RESOLUBILIDAD
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62304509A JPH01146826A (ja) | 1987-12-03 | 1987-12-03 | 白金化合物の凍結乾燥製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2031987T3 true ES2031987T3 (es) | 1993-01-01 |
Family
ID=17933895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888119857T Expired - Lifetime ES2031987T3 (es) | 1987-12-03 | 1988-11-29 | Un metodo para producir una preparacion liofilizada de un compuesto de platino. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4954522A (es) |
EP (1) | EP0318906B1 (es) |
JP (1) | JPH01146826A (es) |
KR (1) | KR890009386A (es) |
CN (1) | CN1034311A (es) |
DE (1) | DE3871092D1 (es) |
ES (1) | ES2031987T3 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5455270A (en) * | 1993-08-11 | 1995-10-03 | Bristol-Myers Squibb Co. | Stabilized solutions of platinum(II) antitumor agents |
CZ292170B6 (cs) * | 1998-08-14 | 2003-08-13 | Pliva-Lachema A.S. | Farmaceutická kompozice s protinádorovým účinkem na bázi carboplatiny |
CN1283242C (zh) * | 2001-09-21 | 2006-11-08 | 大日本住友制药株式会社 | 冻干制剂 |
TW200539855A (en) * | 2004-03-15 | 2005-12-16 | Wyeth Corp | Calicheamicin conjugates |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4310515A (en) * | 1978-05-30 | 1982-01-12 | Bristol-Myers Company | Pharmaceutical compositions of cisplatin |
DE2925009A1 (de) * | 1979-06-21 | 1981-01-08 | Basf Ag | Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung |
DK500185A (da) * | 1984-11-02 | 1986-05-03 | Johnson Matthey Plc | Oploeseliggjort platinforbindelse |
US4737589A (en) * | 1985-08-27 | 1988-04-12 | Nippon Kayaku Kabushiki Kaisha | Platinum Complexes |
JPH0665648B2 (ja) * | 1985-09-25 | 1994-08-24 | 塩野義製薬株式会社 | 白金系抗癌物質の安定な凍結真空乾燥製剤 |
-
1987
- 1987-12-03 JP JP62304509A patent/JPH01146826A/ja active Pending
-
1988
- 1988-11-22 US US07/275,008 patent/US4954522A/en not_active Expired - Fee Related
- 1988-11-29 ES ES198888119857T patent/ES2031987T3/es not_active Expired - Lifetime
- 1988-11-29 EP EP88119857A patent/EP0318906B1/en not_active Expired - Lifetime
- 1988-11-29 DE DE8888119857T patent/DE3871092D1/de not_active Expired - Fee Related
- 1988-12-01 CN CN88108262A patent/CN1034311A/zh active Pending
- 1988-12-01 KR KR1019880015997A patent/KR890009386A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0318906B1 (en) | 1992-05-13 |
EP0318906A1 (en) | 1989-06-07 |
KR890009386A (ko) | 1989-08-01 |
JPH01146826A (ja) | 1989-06-08 |
CN1034311A (zh) | 1989-08-02 |
DE3871092D1 (de) | 1992-06-17 |
US4954522A (en) | 1990-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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