ES2005159A6 - Procedimiento para diagnostico y seguimiento de hepatopatias mediante determinacion de factor de crecimiento hepatico en plasma yno suero sanguineo. - Google Patents

Procedimiento para diagnostico y seguimiento de hepatopatias mediante determinacion de factor de crecimiento hepatico en plasma yno suero sanguineo.

Info

Publication number
ES2005159A6
ES2005159A6 ES8701083A ES8701083A ES2005159A6 ES 2005159 A6 ES2005159 A6 ES 2005159A6 ES 8701083 A ES8701083 A ES 8701083A ES 8701083 A ES8701083 A ES 8701083A ES 2005159 A6 ES2005159 A6 ES 2005159A6
Authority
ES
Spain
Prior art keywords
growth factor
liver growth
liver
hepatopathies
albumin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701083A
Other languages
English (en)
Inventor
Gil Juan Jose Diaz
Marin Pedro Escartin
Canero Rafael Garcia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inst Llorente S A
Original Assignee
Inst Llorente S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Llorente S A filed Critical Inst Llorente S A
Priority to ES8701083A priority Critical patent/ES2005159A6/es
Priority to EP88500038A priority patent/EP0287493A3/en
Priority to JP63091220A priority patent/JPS6445399A/ja
Publication of ES2005159A6 publication Critical patent/ES2005159A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/728—Bilirubin; including biliverdin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA DIAGNOSTICO Y SEGUIMIENTO DE HEPATOPATIAS MEDIANTE DETERMINACION DE FACTOR DE CRECIMIENTO HEPATICO EN PLASMA Y/O SUERO SANGUINEO, EN EL QUE SE EXTRAE SANGRE A UN INDIVIDUO SOSPECHOSO DE PADECER LA ENFERMEDAD, SE SEPARAN PLASMA Y/O SUERO DE LOS DEMAS COMPONENTES DE LA SANGRE, SE DETERMINA LA CONCENTRACION DE FACTOR DE CRECIMIENTO HEPATICO HUMANO (H-LGF), CONSTITUIDO POR UN COMPLEJO DE ALBUMINA Y BILIRRUBINA, EN DICHO PLASMA Y/O SUERO, Y SE COMPARA EL VALOR OBTENIDO EN LA DETERMINACION CON UN VALOR DE REFERENCIA DEL H-LGF EN LA HEPATITIS AGUDA TIPO B, SIENDO INDETECTABLE EL H-LGF EN PLASMA Y/O SUERO DE INDIVIDUOS CONTROLES SANOS. EL INVENTO ES ESPECIALMENTE UTIL EN RELACION CON DIVERSOS TIPOS DE HEPATITIS.
ES8701083A 1987-04-14 1987-04-14 Procedimiento para diagnostico y seguimiento de hepatopatias mediante determinacion de factor de crecimiento hepatico en plasma yno suero sanguineo. Expired ES2005159A6 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES8701083A ES2005159A6 (es) 1987-04-14 1987-04-14 Procedimiento para diagnostico y seguimiento de hepatopatias mediante determinacion de factor de crecimiento hepatico en plasma yno suero sanguineo.
EP88500038A EP0287493A3 (en) 1987-04-14 1988-04-11 Liver growth factor
JP63091220A JPS6445399A (en) 1987-04-14 1988-04-13 Hepar growth factor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES8701083A ES2005159A6 (es) 1987-04-14 1987-04-14 Procedimiento para diagnostico y seguimiento de hepatopatias mediante determinacion de factor de crecimiento hepatico en plasma yno suero sanguineo.

Publications (1)

Publication Number Publication Date
ES2005159A6 true ES2005159A6 (es) 1989-03-01

Family

ID=8250453

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701083A Expired ES2005159A6 (es) 1987-04-14 1987-04-14 Procedimiento para diagnostico y seguimiento de hepatopatias mediante determinacion de factor de crecimiento hepatico en plasma yno suero sanguineo.

Country Status (3)

Country Link
EP (1) EP0287493A3 (es)
JP (1) JPS6445399A (es)
ES (1) ES2005159A6 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE222603T1 (de) * 1992-05-18 2002-09-15 Genentech Inc Hepatozytwachstumfaktor variante
US5316921A (en) * 1992-05-18 1994-05-31 Genentech, Inc. Single-chain hepatocyte growth factor variants
US5328837A (en) * 1992-05-18 1994-07-12 Genentech, Inc. Hepatocyte growth factor protease domain variants
ES2325699B1 (es) * 2006-04-21 2010-06-28 Fundacion Para La Investigacion Biomedica Del Hospital Universitario Puerta De Hierro Uso del factor de crecimiento de higado (lgf) como regenerador tisular pleiotropico.

Also Published As

Publication number Publication date
JPS6445399A (en) 1989-02-17
EP0287493A2 (en) 1988-10-19
EP0287493A3 (en) 1989-09-20

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-04-14

FD1A Patent lapsed

Effective date: 19990301