KR890009386A - 백금화합물 동결건조제제 - Google Patents
백금화합물 동결건조제제 Download PDFInfo
- Publication number
- KR890009386A KR890009386A KR1019880015997A KR880015997A KR890009386A KR 890009386 A KR890009386 A KR 890009386A KR 1019880015997 A KR1019880015997 A KR 1019880015997A KR 880015997 A KR880015997 A KR 880015997A KR 890009386 A KR890009386 A KR 890009386A
- Authority
- KR
- South Korea
- Prior art keywords
- platinum compound
- dextran
- weight
- lyophilized agent
- compound lyophilized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 덱스트란 및 시스-1,1-시클로부탄디카르복실레이트(2R)-2-메틸-1,4-부탄디아민백금(Ⅱ)으로 조성된 동결건조제제.
- 제1항에 있어서, 덱스트란의 분자량이 40.000내지 150.000인 동결건조제제.
- 제1항에 있어서, 덱스트란의 조성량이 백금화합물 1중량부에 대하여 약 0.2 내지 약 5중량부인 동결건조제제.
- 제1항에 있어서, 덱스트란의 조성량이 백금화합물 1중량부에 대하여 약0.5 내지 약 2중량부인 동결건조제제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62304509A JPH01146826A (ja) | 1987-12-03 | 1987-12-03 | 白金化合物の凍結乾燥製剤 |
JP62-304509 | 1987-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR890009386A true KR890009386A (ko) | 1989-08-01 |
Family
ID=17933895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880015997A KR890009386A (ko) | 1987-12-03 | 1988-12-01 | 백금화합물 동결건조제제 |
Country Status (7)
Country | Link |
---|---|
US (1) | US4954522A (ko) |
EP (1) | EP0318906B1 (ko) |
JP (1) | JPH01146826A (ko) |
KR (1) | KR890009386A (ko) |
CN (1) | CN1034311A (ko) |
DE (1) | DE3871092D1 (ko) |
ES (1) | ES2031987T3 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5455270A (en) * | 1993-08-11 | 1995-10-03 | Bristol-Myers Squibb Co. | Stabilized solutions of platinum(II) antitumor agents |
CZ292170B6 (cs) * | 1998-08-14 | 2003-08-13 | Pliva-Lachema A.S. | Farmaceutická kompozice s protinádorovým účinkem na bázi carboplatiny |
WO2003026642A1 (fr) * | 2001-09-21 | 2003-04-03 | Sumitomo Pharmaceuticals Co., Ltd. | Preparation pharmaceutique lyophilisee |
AR048098A1 (es) * | 2004-03-15 | 2006-03-29 | Wyeth Corp | Conjugados de caliqueamicina |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4310515A (en) * | 1978-05-30 | 1982-01-12 | Bristol-Myers Company | Pharmaceutical compositions of cisplatin |
DE2925009A1 (de) * | 1979-06-21 | 1981-01-08 | Basf Ag | Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung |
IL76889A0 (en) * | 1984-11-02 | 1986-02-28 | Johnson Matthey Plc | Solubilised platinum compound,method for the production thereof and pharmaceutical compositions containing the same |
US4737589A (en) * | 1985-08-27 | 1988-04-12 | Nippon Kayaku Kabushiki Kaisha | Platinum Complexes |
JPH0665648B2 (ja) * | 1985-09-25 | 1994-08-24 | 塩野義製薬株式会社 | 白金系抗癌物質の安定な凍結真空乾燥製剤 |
-
1987
- 1987-12-03 JP JP62304509A patent/JPH01146826A/ja active Pending
-
1988
- 1988-11-22 US US07/275,008 patent/US4954522A/en not_active Expired - Fee Related
- 1988-11-29 EP EP88119857A patent/EP0318906B1/en not_active Expired - Lifetime
- 1988-11-29 DE DE8888119857T patent/DE3871092D1/de not_active Expired - Fee Related
- 1988-11-29 ES ES198888119857T patent/ES2031987T3/es not_active Expired - Lifetime
- 1988-12-01 CN CN88108262A patent/CN1034311A/zh active Pending
- 1988-12-01 KR KR1019880015997A patent/KR890009386A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US4954522A (en) | 1990-09-04 |
CN1034311A (zh) | 1989-08-02 |
EP0318906A1 (en) | 1989-06-07 |
DE3871092D1 (de) | 1992-06-17 |
ES2031987T3 (es) | 1993-01-01 |
JPH01146826A (ja) | 1989-06-08 |
EP0318906B1 (en) | 1992-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |