KR890009386A - 백금화합물 동결건조제제 - Google Patents

백금화합물 동결건조제제 Download PDF

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Publication number
KR890009386A
KR890009386A KR1019880015997A KR880015997A KR890009386A KR 890009386 A KR890009386 A KR 890009386A KR 1019880015997 A KR1019880015997 A KR 1019880015997A KR 880015997 A KR880015997 A KR 880015997A KR 890009386 A KR890009386 A KR 890009386A
Authority
KR
South Korea
Prior art keywords
platinum compound
dextran
weight
lyophilized agent
compound lyophilized
Prior art date
Application number
KR1019880015997A
Other languages
English (en)
Inventor
신다로오 스즈끼
노리아끼 야나기사와
다까아끼 오오구마
Original Assignee
원본미기재
닛뽕 가야꾸 가부시기 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 닛뽕 가야꾸 가부시기 가이샤 filed Critical 원본미기재
Publication of KR890009386A publication Critical patent/KR890009386A/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Abstract

내용 없음

Description

백금화합물 동결건조제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 덱스트란 및 시스-1,1-시클로부탄디카르복실레이트(2R)-2-메틸-1,4-부탄디아민백금(Ⅱ)으로 조성된 동결건조제제.
  2. 제1항에 있어서, 덱스트란의 분자량이 40.000내지 150.000인 동결건조제제.
  3. 제1항에 있어서, 덱스트란의 조성량이 백금화합물 1중량부에 대하여 약 0.2 내지 약 5중량부인 동결건조제제.
  4. 제1항에 있어서, 덱스트란의 조성량이 백금화합물 1중량부에 대하여 약0.5 내지 약 2중량부인 동결건조제제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880015997A 1987-12-03 1988-12-01 백금화합물 동결건조제제 KR890009386A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP62304509A JPH01146826A (ja) 1987-12-03 1987-12-03 白金化合物の凍結乾燥製剤
JP62-304509 1987-12-03

Publications (1)

Publication Number Publication Date
KR890009386A true KR890009386A (ko) 1989-08-01

Family

ID=17933895

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880015997A KR890009386A (ko) 1987-12-03 1988-12-01 백금화합물 동결건조제제

Country Status (7)

Country Link
US (1) US4954522A (ko)
EP (1) EP0318906B1 (ko)
JP (1) JPH01146826A (ko)
KR (1) KR890009386A (ko)
CN (1) CN1034311A (ko)
DE (1) DE3871092D1 (ko)
ES (1) ES2031987T3 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
CZ292170B6 (cs) * 1998-08-14 2003-08-13 Pliva-Lachema A.S. Farmaceutická kompozice s protinádorovým účinkem na bázi carboplatiny
WO2003026642A1 (fr) * 2001-09-21 2003-04-03 Sumitomo Pharmaceuticals Co., Ltd. Preparation pharmaceutique lyophilisee
AR048098A1 (es) * 2004-03-15 2006-03-29 Wyeth Corp Conjugados de caliqueamicina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310515A (en) * 1978-05-30 1982-01-12 Bristol-Myers Company Pharmaceutical compositions of cisplatin
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
IL76889A0 (en) * 1984-11-02 1986-02-28 Johnson Matthey Plc Solubilised platinum compound,method for the production thereof and pharmaceutical compositions containing the same
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤

Also Published As

Publication number Publication date
US4954522A (en) 1990-09-04
CN1034311A (zh) 1989-08-02
EP0318906A1 (en) 1989-06-07
DE3871092D1 (de) 1992-06-17
ES2031987T3 (es) 1993-01-01
JPH01146826A (ja) 1989-06-08
EP0318906B1 (en) 1992-05-13

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WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid