AR014405A1 - Uretanos y sus analogos tio y ditio, sus sales, el empleo de los mismos para preparar medicamentos y piensos para gallinas ponedoras, los medicamentosy los piensos que contienen estos compuestos, un procedimiento para preparar estos compuestos y un procedimiento para preparar los medicamentos mencio - Google Patents

Uretanos y sus analogos tio y ditio, sus sales, el empleo de los mismos para preparar medicamentos y piensos para gallinas ponedoras, los medicamentosy los piensos que contienen estos compuestos, un procedimiento para preparar estos compuestos y un procedimiento para preparar los medicamentos mencio

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Publication number
AR014405A1
AR014405A1 ARP980106227A ARP980106227A AR014405A1 AR 014405 A1 AR014405 A1 AR 014405A1 AR P980106227 A ARP980106227 A AR P980106227A AR P980106227 A ARP980106227 A AR P980106227A AR 014405 A1 AR014405 A1 AR 014405A1
Authority
AR
Argentina
Prior art keywords
group
alkyl
feeds
isolated
prepare
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
ARP980106227A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of AR014405A1 publication Critical patent/AR014405A1/es
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/56—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02—Monothiocarbamic acids; Derivatives thereof
    • C07C333/06—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/14—Dithiocarbamic acids; Derivatives thereof
    • C07C333/18—Esters of dithiocarbamic acids
    • C07C333/24—Esters of dithiocarbamic acids having nitrogen atoms of dithiocarbamate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Uretanos y sus análogos tio y ditio, que responden a la formula general (I) en la que: m significa los numeros 0 o 1, n significa los numeros 1 o 2, Asignifica un enlace sencillo, un grupo alquileno (C1-8) de cadena lineal o ramificada, ungrupo alquenileno (C2-8) o alquinileno (C2-8), no estando ungrupo insaturado directamente unido al radical Y, X significa un átomo de oxígeno o azufre, Y significa un átomo de oxígeno o azufre, R1 significa ungrupo alquilo (C1-8) de cadenalineal o ramificada, un grupo alquenilo (C1-6) o un grupo alquinilo (C1-6), estando aislado el enlace multiple del enlacenitrogeno-carbono, R2 significa un átomo de hidrogeno, un grupo alquilo (C1-8) de cadena lineal o ramificada, que puede estarsustituido con un grupo hidroxio alcoxi, un grupo alquenilo (C1-6) o un grupo alquinilo (C1-6), no estando unido un sustituyente hidroxi o alcoxi en la posicion I, y estando aislado unenlace multiple del enlace nitrogeno-carbono, o R1 y R2,junto con el áto mo de nitrogeno significa un anillo heterocíclico saturado de 5 a 7 miembros, en elque un grupo metileno aislado del átomo de nitrogeno puede estar reemplazado por un átomo de oxígeno o azufre, por un grupo -NH o -N(alquilo), R3a R6, quepueden s er iguales o diferentes, significan átomos de hidrogeno o grupos alquilo, R7 significa un grupo alquilo (C1-6) de cadena lineal o ramificada, unun grupo alquenilo (C1-6) o un grupo alquinilo (C1-6), estando aislado elenlace multiple del enlace nitrogeno-carbono, R8 significa un grupocicloalquilo (C3-7), un grupo fenilo o naftilo eventualmente sustituido con uno o dos átomos de halogeno, con un grupo alquilo, alcoxi, trifluorometilo o cianoo, si A no representaun enlace sencillo, s ignifica también un átomo de hidrogeno, en donde, si no se ha mencionado otra cosa, los grupos alquilo
ARP980106227A 1997-12-10 1998-12-09 Uretanos y sus analogos tio y ditio, sus sales, el empleo de los mismos para preparar medicamentos y piensos para gallinas ponedoras, los medicamentosy los piensos que contienen estos compuestos, un procedimiento para preparar estos compuestos y un procedimiento para preparar los medicamentos mencio Withdrawn AR014405A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19754795A DE19754795A1 (de) 1997-12-10 1997-12-10 Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
AR014405A1 true AR014405A1 (es) 2001-02-28

Family

ID=7851380

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980106227A Withdrawn AR014405A1 (es) 1997-12-10 1998-12-09 Uretanos y sus analogos tio y ditio, sus sales, el empleo de los mismos para preparar medicamentos y piensos para gallinas ponedoras, los medicamentosy los piensos que contienen estos compuestos, un procedimiento para preparar estos compuestos y un procedimiento para preparar los medicamentos mencio

Country Status (30)

Country Link
US (1) US6346545B1 (es)
EP (1) EP1045832B1 (es)
JP (1) JP4001317B2 (es)
KR (1) KR20010024708A (es)
CN (1) CN1281431A (es)
AR (1) AR014405A1 (es)
AT (1) ATE291570T1 (es)
AU (1) AU747173B2 (es)
BG (1) BG104501A (es)
BR (1) BR9813545A (es)
CA (1) CA2310055C (es)
CO (1) CO5290251A1 (es)
CZ (1) CZ20002150A3 (es)
DE (2) DE19754795A1 (es)
EA (1) EA003298B1 (es)
EE (1) EE200000340A (es)
HR (1) HRP980621A2 (es)
HU (1) HUP0100292A3 (es)
ID (1) ID21432A (es)
IL (1) IL135737A0 (es)
NO (1) NO20002968L (es)
NZ (1) NZ505594A (es)
PE (1) PE133599A1 (es)
PL (1) PL341654A1 (es)
SK (1) SK8602000A3 (es)
TR (1) TR200001636T2 (es)
UY (1) UY25288A1 (es)
WO (1) WO1999029662A2 (es)
YU (1) YU35500A (es)
ZA (1) ZA9811263B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100116675A (ko) * 2008-02-22 2010-11-01 바스프 에스이 ３'-브로민-２,３,４,６'-테트라메톡시-２',６-디메틸벤조페논을 포함하는 살진균성 조성물
WO2012092114A2 (en) * 2010-12-27 2012-07-05 The Curators Of The University Of Missouri Oxidosqualene cyclase as a protein target for anticancer therapeutics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2025490C (en) * 1989-09-22 2003-09-16 James R. Mccarthy Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis
US5011859A (en) * 1990-03-30 1991-04-30 Merrell Dow Pharmaceuticals Inc. Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase
CA2047375C (en) * 1990-07-25 2003-04-15 Charlotte L. Barney Piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis
US5084461A (en) * 1991-03-27 1992-01-28 Merrell Dow Pharmaceuticals Inc. Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis
DE4303840A1 (de) * 1992-10-22 1994-08-11 Thomae Gmbh Dr K Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
US5466687A (en) 1992-10-22 1995-11-14 Dr. Karl Thomae Gmbh Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation
DE4239151A1 (de) 1992-11-20 1994-05-26 Thomae Gmbh Dr K N,N-Disubstituierte Arylcycloalkylamine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4239150A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4438020A1 (de) * 1994-10-25 1996-05-02 Thomae Gmbh Dr K N-substituierte Arylcyclohexylacylamine, ihre Salze mit physiologisch verträglichen organischen oder anorganischen Säuren, Verfahren zur Herstellung dieser Verbindungen und diese enthaltende Arzneimittel

Also Published As

Publication number Publication date
EE200000340A (et) 2001-08-15
SK8602000A3 (en) 2000-11-07
DE19754795A1 (de) 1999-06-17
TR200001636T2 (tr) 2001-08-21
PE133599A1 (es) 2000-01-13
JP4001317B2 (ja) 2007-10-31
NO20002968D0 (no) 2000-06-09
CA2310055C (en) 2008-09-23
NO20002968L (no) 2000-08-09
HRP980621A2 (en) 1999-08-31
BR9813545A (pt) 2000-10-10
YU35500A (sh) 2002-09-19
BG104501A (bg) 2001-03-30
CO5290251A1 (es) 2003-06-27
CN1281431A (zh) 2001-01-24
WO1999029662A3 (de) 1999-08-19
AU1759399A (en) 1999-06-28
WO1999029662A2 (de) 1999-06-17
KR20010024708A (ko) 2001-03-26
UY25288A1 (es) 2000-12-29
EP1045832A2 (de) 2000-10-25
PL341654A1 (en) 2001-04-23
AU747173B2 (en) 2002-05-09
JP2001525393A (ja) 2001-12-11
EP1045832B1 (de) 2005-03-23
IL135737A0 (en) 2001-05-20
ZA9811263B (en) 2000-06-09
US20020019536A1 (en) 2002-02-14
HUP0100292A2 (hu) 2001-07-30
US6346545B1 (en) 2002-02-12
EA200000633A1 (ru) 2000-12-25
ATE291570T1 (de) 2005-04-15
HUP0100292A3 (en) 2002-11-28
ID21432A (id) 1999-06-10
CA2310055A1 (en) 1999-06-17
NZ505594A (en) 2001-11-30
CZ20002150A3 (cs) 2001-11-14
EA003298B1 (ru) 2003-04-24
DE59812686D1 (de) 2005-04-28

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