HUP0100292A3 - Novel urethanes, thio and dithio analogues, the salts thereof, medicaments containing said compounds, use and method for the production thereof - Google Patents
Novel urethanes, thio and dithio analogues, the salts thereof, medicaments containing said compounds, use and method for the production thereofInfo
- Publication number
- HUP0100292A3 HUP0100292A3 HU0100292A HUP0100292A HUP0100292A3 HU P0100292 A3 HUP0100292 A3 HU P0100292A3 HU 0100292 A HU0100292 A HU 0100292A HU P0100292 A HUP0100292 A HU P0100292A HU P0100292 A3 HUP0100292 A3 HU P0100292A3
- Authority
- HU
- Hungary
- Prior art keywords
- thio
- salts
- compounds
- production
- medicaments containing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000004119 disulfanediyl group Chemical group *SS* 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 title 1
- 150000003673 urethanes Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/56—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/06—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/14—Dithiocarbamic acids; Derivatives thereof
- C07C333/18—Esters of dithiocarbamic acids
- C07C333/24—Esters of dithiocarbamic acids having nitrogen atoms of dithiocarbamate groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19754795A DE19754795A1 (de) | 1997-12-10 | 1997-12-10 | Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| PCT/EP1998/007962 WO1999029662A2 (de) | 1997-12-10 | 1998-12-08 | Urethane, ihre thio- und dithioanaloga, deren salze, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0100292A2 HUP0100292A2 (hu) | 2001-07-30 |
| HUP0100292A3 true HUP0100292A3 (en) | 2002-11-28 |
Family
ID=7851380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0100292A HUP0100292A3 (en) | 1997-12-10 | 1998-12-08 | Novel urethanes, thio and dithio analogues, the salts thereof, medicaments containing said compounds, use and method for the production thereof |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6346545B1 (hu) |
| EP (1) | EP1045832B1 (hu) |
| JP (1) | JP4001317B2 (hu) |
| KR (1) | KR20010024708A (hu) |
| CN (1) | CN1281431A (hu) |
| AR (1) | AR014405A1 (hu) |
| AT (1) | ATE291570T1 (hu) |
| AU (1) | AU747173B2 (hu) |
| BG (1) | BG104501A (hu) |
| BR (1) | BR9813545A (hu) |
| CA (1) | CA2310055C (hu) |
| CO (1) | CO5290251A1 (hu) |
| CZ (1) | CZ20002150A3 (hu) |
| DE (2) | DE19754795A1 (hu) |
| EA (1) | EA003298B1 (hu) |
| EE (1) | EE200000340A (hu) |
| HR (1) | HRP980621A2 (hu) |
| HU (1) | HUP0100292A3 (hu) |
| ID (1) | ID21432A (hu) |
| IL (1) | IL135737A0 (hu) |
| NO (1) | NO20002968L (hu) |
| NZ (1) | NZ505594A (hu) |
| PE (1) | PE133599A1 (hu) |
| PL (1) | PL341654A1 (hu) |
| SK (1) | SK8602000A3 (hu) |
| TR (1) | TR200001636T2 (hu) |
| UY (1) | UY25288A1 (hu) |
| WO (1) | WO1999029662A2 (hu) |
| YU (1) | YU35500A (hu) |
| ZA (1) | ZA9811263B (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2715310A1 (en) * | 2008-02-22 | 2009-08-27 | Basf Se | Fungicidal compositions comprising 3'-bromine-2,3,4,6'-tetramethoxy-2'-6-dimethylbenzophenone |
| CA2822207A1 (en) * | 2010-12-27 | 2012-07-05 | The Curators Of The University Of Missouri | Oxidosqualene cyclase as a protein target for anticancer therapeutics |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2025490C (en) * | 1989-09-22 | 2003-09-16 | James R. Mccarthy | Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis |
| US5011859A (en) * | 1990-03-30 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase |
| ZA915659B (en) * | 1990-07-25 | 1992-05-27 | Merrell Dow Pharma | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis |
| US5084461A (en) * | 1991-03-27 | 1992-01-28 | Merrell Dow Pharmaceuticals Inc. | Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis |
| US5466687A (en) | 1992-10-22 | 1995-11-14 | Dr. Karl Thomae Gmbh | Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation |
| DE4303840A1 (de) * | 1992-10-22 | 1994-08-11 | Thomae Gmbh Dr K | Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| DE4239151A1 (de) | 1992-11-20 | 1994-05-26 | Thomae Gmbh Dr K | N,N-Disubstituierte Arylcycloalkylamine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| DE4239150A1 (de) | 1992-11-20 | 1994-05-26 | Thomae Gmbh Dr K | O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| DE4438020A1 (de) * | 1994-10-25 | 1996-05-02 | Thomae Gmbh Dr K | N-substituierte Arylcyclohexylacylamine, ihre Salze mit physiologisch verträglichen organischen oder anorganischen Säuren, Verfahren zur Herstellung dieser Verbindungen und diese enthaltende Arzneimittel |
-
1997
- 1997-12-10 DE DE19754795A patent/DE19754795A1/de not_active Withdrawn
-
1998
- 1998-12-07 PE PE1998001189A patent/PE133599A1/es not_active Application Discontinuation
- 1998-12-07 UY UY25288A patent/UY25288A1/es unknown
- 1998-12-07 ID IDP981585A patent/ID21432A/id unknown
- 1998-12-08 EA EA200000633A patent/EA003298B1/ru not_active IP Right Cessation
- 1998-12-08 EP EP98962422A patent/EP1045832B1/de not_active Expired - Lifetime
- 1998-12-08 EE EEP200000340A patent/EE200000340A/xx unknown
- 1998-12-08 PL PL98341654A patent/PL341654A1/xx not_active Application Discontinuation
- 1998-12-08 YU YU35500A patent/YU35500A/sh unknown
- 1998-12-08 AU AU17593/99A patent/AU747173B2/en not_active Ceased
- 1998-12-08 CZ CZ20002150A patent/CZ20002150A3/cs unknown
- 1998-12-08 BR BR9813545-7A patent/BR9813545A/pt not_active IP Right Cessation
- 1998-12-08 JP JP2000524259A patent/JP4001317B2/ja not_active Expired - Fee Related
- 1998-12-08 IL IL13573798A patent/IL135737A0/xx unknown
- 1998-12-08 WO PCT/EP1998/007962 patent/WO1999029662A2/de active IP Right Grant
- 1998-12-08 AT AT98962422T patent/ATE291570T1/de not_active IP Right Cessation
- 1998-12-08 HU HU0100292A patent/HUP0100292A3/hu unknown
- 1998-12-08 TR TR2000/01636T patent/TR200001636T2/xx unknown
- 1998-12-08 DE DE59812686T patent/DE59812686D1/de not_active Expired - Lifetime
- 1998-12-08 CA CA002310055A patent/CA2310055C/en not_active Expired - Fee Related
- 1998-12-08 NZ NZ505594A patent/NZ505594A/en unknown
- 1998-12-08 CN CN98811960A patent/CN1281431A/zh active Pending
- 1998-12-08 SK SK860-2000A patent/SK8602000A3/sk unknown
- 1998-12-08 KR KR1020007006319A patent/KR20010024708A/ko not_active Application Discontinuation
- 1998-12-09 ZA ZA9811263A patent/ZA9811263B/xx unknown
- 1998-12-09 CO CO98073124A patent/CO5290251A1/es not_active Application Discontinuation
- 1998-12-09 AR ARP980106227A patent/AR014405A1/es not_active Withdrawn
- 1998-12-09 HR HR19754795.8A patent/HRP980621A2/hr not_active Application Discontinuation
-
1999
- 1999-03-24 US US09/275,318 patent/US6346545B1/en not_active Expired - Lifetime
-
2000
- 2000-06-02 BG BG104501A patent/BG104501A/bg active Pending
- 2000-06-09 NO NO20002968A patent/NO20002968L/no not_active Application Discontinuation
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