ES2144786T3 - Derivados de benceno. - Google Patents

Derivados de benceno.

Info

Publication number
ES2144786T3
ES2144786T3 ES96938545T ES96938545T ES2144786T3 ES 2144786 T3 ES2144786 T3 ES 2144786T3 ES 96938545 T ES96938545 T ES 96938545T ES 96938545 T ES96938545 T ES 96938545T ES 2144786 T3 ES2144786 T3 ES 2144786T3
Authority
ES
Spain
Prior art keywords
group
substituted
benzene derivatives
halogen
pharmacological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96938545T
Other languages
English (en)
Inventor
Masaichi Hasegawa
Takumi Takeyasu
Naoki Tsuchiya
Naoki Hase
Katsushi Takahashi
Takashi Kamimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ES2144786T3 publication Critical patent/ES2144786T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NUEVOS DERIVADOS DE BENCENO DE FORMULA (I) INDICADA MAS ADELANTE, SALES FARMACOLOGICAS DE LOS MISMOS, SOLVATOS FARMACOLOGICOS DE LOS DERIVADOS Y SALES DE BENCENO ANTES MENCIONADOS, COMPUESTOS FARMACEUTICOS QUE CONTIENEN LOS COMPUESTOS ANTES MENCIONADOS COMO PRINCIPIOS ACTIVOS, Y ESPECIALMENTE MEDICAMENTOS PARA LA PROFILAXIS Y TRATAMIENTO DE ENFERMEDADES ALERGICAS. DONDE R{SUP,1}= H, GRUPO ALQUILO C{SUB,1} DE CADENA LINEAL O RAMIFICADA (QUE PUEDE SER SUSTITUIDO POR UNO O MAS GRUPOS ARILOXI C{SUB,6} {SUB,7} TUIDO POR UNO O MAS HALOGENOS, METILO O METOXI), O ALQUENILO C{SUB,3} POS FENILO; A= O, S O GRUPO CH{SUB,2}, B= GRUPO CO O CZ{SUB,2}CO (Z= H O F), R{SUP,2}= H O GRUPO ALQUILO C{SUB,1} C{SUB,4}, X= GRUPO HALOGENO O METILO, E Y= H, NO{SUB,2} O GRUPO CN.
ES96938545T 1995-11-27 1996-11-26 Derivados de benceno. Expired - Lifetime ES2144786T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30722295 1995-11-27
JP22836796 1996-08-29

Publications (1)

Publication Number Publication Date
ES2144786T3 true ES2144786T3 (es) 2000-06-16

Family

ID=26528211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96938545T Expired - Lifetime ES2144786T3 (es) 1995-11-27 1996-11-26 Derivados de benceno.

Country Status (12)

Country Link
US (1) US5808144A (es)
EP (1) EP0806412B1 (es)
JP (1) JP3117466B2 (es)
KR (1) KR100309754B1 (es)
CN (1) CN1081623C (es)
AT (1) ATE191458T1 (es)
AU (1) AU703092B2 (es)
CA (1) CA2210579C (es)
DE (1) DE69607597T2 (es)
ES (1) ES2144786T3 (es)
TW (1) TW346483B (es)
WO (1) WO1997019910A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2337098C (en) * 1998-07-24 2008-08-05 Teijin Limited Anthranilic acid derivatives
US6627743B1 (en) * 1999-12-03 2003-09-30 Abbott Laboratories 6-O-methylerythromycin A crystal form III
WO2001060354A1 (fr) * 2000-02-15 2001-08-23 Teijin Limited Medicament anticancereux comprenant un derive d'acide anthranilique en tant qu'ingredient actif
GB0319124D0 (en) * 2003-08-14 2003-09-17 Smithkline Beecham Corp Chemical compounds
WO2020252195A1 (en) * 2019-06-11 2020-12-17 The Wistar Institute Of Anatomy And Biology Telomerase reverse transcriptase degraders and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE736787A (fr) * 1968-08-02 1970-01-30 Roussel Uclaf Dérivés de l'acide anthranilique et procédé de préparation
JPS60116657A (ja) * 1983-11-30 1985-06-24 Ono Pharmaceut Co Ltd アニリン誘導体
WO1993015043A1 (en) * 1992-01-24 1993-08-05 Yoshitomi Pharmaceutical Industries, Ltd. Arylalkananilide compound and pharmaceutical use thereof
US5783593A (en) * 1993-11-04 1998-07-21 Abbott Laboratories Inhibitors of squalene synthetase and protein farnesyltransferase

Also Published As

Publication number Publication date
JP3117466B2 (ja) 2000-12-11
KR19980701699A (ko) 1998-06-25
CN1081623C (zh) 2002-03-27
US5808144A (en) 1998-09-15
CA2210579C (en) 2003-03-11
EP0806412A4 (es) 1997-11-12
CN1173169A (zh) 1998-02-11
TW346483B (en) 1998-12-01
AU703092B2 (en) 1999-03-18
KR100309754B1 (ko) 2002-05-30
ATE191458T1 (de) 2000-04-15
DE69607597T2 (de) 2000-08-24
DE69607597D1 (de) 2000-05-11
EP0806412A1 (en) 1997-11-12
CA2210579A1 (en) 1997-06-05
AU7590296A (en) 1997-06-19
EP0806412B1 (en) 2000-04-05
WO1997019910A1 (en) 1997-06-05

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