AR011163A1 - Compuestos de siete anillo condensados, sustituidos con sulfonamida preparado farmaceutico y su empleo para la preparacion de un medicamento - Google Patents
Compuestos de siete anillo condensados, sustituidos con sulfonamida preparado farmaceutico y su empleo para la preparacion de un medicamentoInfo
- Publication number
- AR011163A1 AR011163A1 ARP980100811A ARP980100811A AR011163A1 AR 011163 A1 AR011163 A1 AR 011163A1 AR P980100811 A ARP980100811 A AR P980100811A AR P980100811 A ARP980100811 A AR P980100811A AR 011163 A1 AR011163 A1 AR 011163A1
- Authority
- AR
- Argentina
- Prior art keywords
- atoms
- group
- replaced
- hydrogen
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuestos bicíclicos sustituidos con sulfonamida, que comprenden la formula (I) en donde X1 significa -O-, -S-, -SO-, -SO2, -CR(1)R(2)-, -NR(6)-,R(1) y R(2) significan, independientemente uno de otro, hidrogeno CF3, C2F5, C3F7, alquilo con1, 2, 3, 4, 5 o 6 átomos de C o fenilo, que está sustituido ono con 1 o 2 sustituyentes elegidos del grupo consistente en F, Cl, Br, I, CF3, NO2, CN, NH2, OH, metilo, etilo, etoxi, dimetilamino, sulfamoilo, metisulfoniloy metilsulfonilamino; o R(1)y R(2) significan juntos una cadena alquileno con 2 a 10 átomos de C; R(6) significa hidrogeno o -CnH2n-R(8), pudiendo estarreemplazado un grupo CH2 del grupo CnH2n por -O-, -CH=CH-, -C:::C-, -CO-, -CO-O-, -O-CO-, -S-, -SO-, -SO2-, -NR(9)- o -CONR(9)-; R(9) significahidrogeno o alquilo con 1 a 3 átomos de C; N significa dee 0 a 8; R(8) significa hidrogeno, CF3, C2F5, C3F7, cicloalquilo con 3 a 8 átomos de C,dimetilamino, dietilamino, 1-piperidilo, 1-pirrolidinilo, 4-morfolinilo,4-metilpiperazin-1-ilo, piridilo, tienilo, imidazolilo o fenilo, estandopiridilo, tienilo, imidazolilo y fenilo sustituido o no con 1 o 2 sustituyentes elegidos del grupo consistente en F, Cl, Br, I, CF3, NO2, CN, NH2, OH, metilo,etilo, metoxi, dimetilamino, sulfamoilo, metilsulfonilo y metilsulfonilamino; X2 significa -CR(1)R(2)- o -CR(2)R(10)-; o X2 significa, si X3 y X1 significan-CR(1)R(2)-, también -O-, -S-, -SO-, -SO2- o -NR(6)-, estando definidos los radicales R(1), R(2) y R(6) como se indica en X1, pero siendo independientesde los significados de los radicales en X1; R(10) significa, junto con R(7), un enlace; X3 significa -CR(1)R(2)-; o X3 significa, si X2 y X4 significanCR(1)R(2)-, también -O-, -S-, -SO-, -SO2- o -NR(6)-, estando definidos los radicales R(1), R(2) y R(6) como se indica en X1, pero siendo independientes de
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19707656A DE19707656A1 (de) | 1997-02-26 | 1997-02-26 | Sulfonamid-substituierte anellierte 7-Ring-Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR011163A1 true AR011163A1 (es) | 2000-08-02 |
Family
ID=7821518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980100811A AR011163A1 (es) | 1997-02-26 | 1998-02-24 | Compuestos de siete anillo condensados, sustituidos con sulfonamida preparado farmaceutico y su empleo para la preparacion de un medicamento |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0861836B1 (es) |
| JP (1) | JP4171097B2 (es) |
| KR (1) | KR19980071625A (es) |
| CN (1) | CN1110490C (es) |
| AR (1) | AR011163A1 (es) |
| AT (1) | ATE286039T1 (es) |
| AU (1) | AU737461B2 (es) |
| BR (1) | BR9800207A (es) |
| CA (1) | CA2230349A1 (es) |
| CZ (1) | CZ53998A3 (es) |
| DE (2) | DE19707656A1 (es) |
| ES (1) | ES2234044T3 (es) |
| HR (1) | HRP980098A2 (es) |
| HU (1) | HUP9800395A3 (es) |
| ID (1) | ID19931A (es) |
| IL (1) | IL123454A0 (es) |
| MX (1) | MX9801516A (es) |
| NO (1) | NO980785L (es) |
| NZ (1) | NZ329838A (es) |
| PL (1) | PL325045A1 (es) |
| RU (1) | RU2223264C2 (es) |
| SK (1) | SK283312B6 (es) |
| TR (1) | TR199800301A2 (es) |
| TW (1) | TW452574B (es) |
| ZA (1) | ZA981562B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19858253A1 (de) * | 1998-12-17 | 2000-06-21 | Aventis Pharma Gmbh | Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden |
| DE19929076A1 (de) * | 1999-06-25 | 2000-12-28 | Aventis Pharma Gmbh | Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| US7119112B2 (en) * | 2002-02-28 | 2006-10-10 | Icagen, Inc. | Sulfonamides as potassium channel blockers |
| TW200403058A (en) | 2002-04-19 | 2004-03-01 | Bristol Myers Squibb Co | Heterocyclo inhibitors of potassium channel function |
| WO2004043367A2 (en) | 2002-11-06 | 2004-05-27 | Bristol-Myers Squibb Company | Fused heterocyclic compounds and use thereof |
| US20120309796A1 (en) * | 2011-06-06 | 2012-12-06 | Fariborz Firooznia | Benzocycloheptene acetic acids |
| RU2538962C1 (ru) * | 2013-11-19 | 2015-01-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) | Противогрибковые соединения на основе производных 3,5,8-триоксабицикло[5.1.0]октана |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| GB9225860D0 (en) * | 1992-12-11 | 1993-02-03 | Smithkline Beecham Plc | Novel treatment |
-
1997
- 1997-02-26 DE DE19707656A patent/DE19707656A1/de not_active Withdrawn
-
1998
- 1998-02-20 BR BR9800207A patent/BR9800207A/pt not_active IP Right Cessation
- 1998-02-20 AT AT98102952T patent/ATE286039T1/de not_active IP Right Cessation
- 1998-02-20 DE DE59812423T patent/DE59812423D1/de not_active Expired - Lifetime
- 1998-02-20 EP EP98102952A patent/EP0861836B1/de not_active Expired - Lifetime
- 1998-02-20 ES ES98102952T patent/ES2234044T3/es not_active Expired - Lifetime
- 1998-02-24 TR TR1998/00301A patent/TR199800301A2/xx unknown
- 1998-02-24 AR ARP980100811A patent/AR011163A1/es unknown
- 1998-02-24 CZ CZ98539A patent/CZ53998A3/cs unknown
- 1998-02-24 NZ NZ329838A patent/NZ329838A/xx unknown
- 1998-02-24 KR KR1019980005695A patent/KR19980071625A/ko not_active Application Discontinuation
- 1998-02-24 SK SK239-98A patent/SK283312B6/sk unknown
- 1998-02-24 CA CA002230349A patent/CA2230349A1/en not_active Abandoned
- 1998-02-24 ID IDP980258A patent/ID19931A/id unknown
- 1998-02-25 HR HR19707656.4A patent/HRP980098A2/hr not_active Application Discontinuation
- 1998-02-25 RU RU98104586/04A patent/RU2223264C2/ru not_active IP Right Cessation
- 1998-02-25 IL IL12345498A patent/IL123454A0/xx unknown
- 1998-02-25 JP JP04365298A patent/JP4171097B2/ja not_active Expired - Fee Related
- 1998-02-25 CN CN98105329A patent/CN1110490C/zh not_active Expired - Fee Related
- 1998-02-25 ZA ZA981562A patent/ZA981562B/xx unknown
- 1998-02-25 MX MX9801516A patent/MX9801516A/es not_active IP Right Cessation
- 1998-02-25 AU AU56333/98A patent/AU737461B2/en not_active Ceased
- 1998-02-25 HU HU9800395A patent/HUP9800395A3/hu unknown
- 1998-02-25 NO NO980785A patent/NO980785L/no unknown
- 1998-02-26 PL PL98325045A patent/PL325045A1/xx unknown
- 1998-03-27 TW TW087102578A patent/TW452574B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SK23998A3 (en) | 1998-09-09 |
| NZ329838A (en) | 1999-07-29 |
| JP4171097B2 (ja) | 2008-10-22 |
| JPH10287641A (ja) | 1998-10-27 |
| TR199800301A2 (xx) | 1998-09-21 |
| MX9801516A (es) | 1998-11-30 |
| CN1110490C (zh) | 2003-06-04 |
| HUP9800395A2 (hu) | 2001-04-28 |
| ES2234044T3 (es) | 2005-06-16 |
| SK283312B6 (sk) | 2003-05-02 |
| NO980785L (no) | 1998-08-27 |
| CA2230349A1 (en) | 1998-08-26 |
| HUP9800395A3 (en) | 2002-04-29 |
| EP0861836A1 (de) | 1998-09-02 |
| CN1193017A (zh) | 1998-09-16 |
| CZ53998A3 (cs) | 1998-09-16 |
| AU5633398A (en) | 1998-09-03 |
| DE19707656A1 (de) | 1998-08-27 |
| HRP980098A2 (en) | 1998-12-31 |
| KR19980071625A (ko) | 1998-10-26 |
| ZA981562B (en) | 1998-08-26 |
| RU2223264C2 (ru) | 2004-02-10 |
| ATE286039T1 (de) | 2005-01-15 |
| EP0861836B1 (de) | 2004-12-29 |
| ID19931A (id) | 1998-08-27 |
| AU737461B2 (en) | 2001-08-23 |
| TW452574B (en) | 2001-09-01 |
| DE59812423D1 (de) | 2005-02-03 |
| BR9800207A (pt) | 1999-05-18 |
| IL123454A0 (en) | 1998-09-24 |
| NO980785D0 (no) | 1998-02-25 |
| PL325045A1 (en) | 1998-08-31 |
| HU9800395D0 (en) | 1998-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1169298T3 (da) | Farmaceutiske forbindelser | |
| SV2008001369A (es) | Benzimidazoles | |
| UY28514A1 (es) | Nuevos compuestos | |
| UY27516A1 (es) | Bencimidazoles | |
| YU21803A (sh) | Farmaceutski aktivni derivati sulfonamida koji imaju i lipofilne i jonizujuće osobine kao inhibitori protein-junkinaza | |
| NO20005535D0 (no) | Pyrazol-derivater som P-38 MAP kinase-inhibitorer | |
| AR029383A1 (es) | Moleculas pequenas, los intermediarios para su sintesis, las composiciones farmaceuticas que las contienen y su uso para preparar un medicamento destinado al tratamiento o la profilaxis de enfermedades inflamatorias o mediadas por celulas inmunes | |
| BG66085B1 (bg) | Фенилаланинови производни | |
| DOP2002000433A (es) | 2-tio-3,5-diciano-4-fenil-6-aminopiridinas substituidas y su uso | |
| EA200700192A1 (ru) | Производные фталазина в качестве ингибиторов parp | |
| ES2164920T3 (es) | Nuevos derivados heterociclicos y uso medicinal de los mismos. | |
| AR045255A1 (es) | Derivados de 1,2 benzodiazol | |
| EA200000731A1 (ru) | Альфа-аминоамидные производные, полезные в качестве анальгетических агентов | |
| HRP20070194T3 (en) | N-thiazol-2-yl-benzamide derivatives | |
| AR002268A1 (es) | Antagonistas de vasopresina de benzacepina triciclicos, un procedimiento para su preparacion, una composicion farmaceutica que los contiene y el uso dedichos compuestos para preparar composiciones farmaceuticas. | |
| AR011163A1 (es) | Compuestos de siete anillo condensados, sustituidos con sulfonamida preparado farmaceutico y su empleo para la preparacion de un medicamento | |
| UY29892A1 (es) | Nuevos derivados de cromano, composiciones farmaceuticas conteniendolos, procesos de preparacion y aplicaciones | |
| PT1181294E (pt) | Novos derivados e analogos da galantamina | |
| BR0212673A (pt) | Espirocìclicas-6,7-dihidro-5h-pirazolo[1,2a]pirazol-1- onas e composição farmacêutica compreendendo as mesmas | |
| AR014915A1 (es) | Cromanos sustituidos con sulfonamida, su utilizacion como medicamentos y preparados farmaceuticos que los contienen | |
| EA200100059A3 (ru) | Новые бензолсульфонамидные производные, способ их получения и содержащие их фармацевтические композиции | |
| EA200101230A1 (ru) | Новые ингибиторы металлопротеаз, метод их получения и содержащие их фармацевтические композиции | |
| MX9405111A (es) | Nuevos derivados de (1-fenil-1-heterociclil)metanol y(1-fenil-1-heterociclil-metilamina). | |
| CO5290255A1 (es) | Pirazolo(4,3-e)diazepinas sustituidas novedosas, composiciones farmaceuticas que las contienen, su uso como productos medicinales y procesos para prepararlas | |
| AR016006A1 (es) | Compuestos condensados con anillo de 5 miembros, sustituidos con sulfonamida, su utilizacion como medicamentos, asi como preparados farmaceuticosque los contienen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |