AR004952A1 - Una composicion oftalmica preservada. - Google Patents

Una composicion oftalmica preservada.

Info

Publication number
AR004952A1
AR004952A1 ARP960104361A ARP010436196A AR004952A1 AR 004952 A1 AR004952 A1 AR 004952A1 AR P960104361 A ARP960104361 A AR P960104361A AR P010436196 A ARP010436196 A AR P010436196A AR 004952 A1 AR004952 A1 AR 004952A1
Authority
AR
Argentina
Prior art keywords
chloride
preferably selected
cyclodextrin
alkylene glycol
hydrochloride
Prior art date
Application number
ARP960104361A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR004952A1 publication Critical patent/AR004952A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Una composicon oftalmica preservada, que comprende una ciclodextrina, una sal de amonio cuaternario, un alquilenglicol y un compuesto farmaceuticamenteactivo. La sal de amonio cuaternario se selecciona preferentemente de cloruro de sepazonio,bro muro de cetiltrimetilamonio (cetrimida), cloruro decetilpiridinio, cloruro de benzoxonio, cloruro de bencetonio, bromuro de domifen (Bradosol) y cloruro de benzalconio. La ciclodextrina se seleccionapreferentemente dealfa-beta-gama-ciclodextr ina, derivados y mezclas de las mismas. El alquilenglicol se selecciona preferentemente de alquilenglicollineal, ramificado y ciclico, que tenga hasta 7 C-atomos.El compuesto farmaceuticamente activo seselecciona preferentemente del gr upo de clorhidratode betaxolol, cloranfenicol, diclofenac, clorhidrato de dipivefrina, levobunolol, levocabastina, clohidrato de pilocarpina y sales u otras salesoftalmicamente aceptables de los mismos.
ARP960104361A 1995-09-18 1996-09-16 Una composicion oftalmica preservada. AR004952A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95810575 1995-09-18

Publications (1)

Publication Number Publication Date
AR004952A1 true AR004952A1 (es) 1999-04-07

Family

ID=8221792

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960104361A AR004952A1 (es) 1995-09-18 1996-09-16 Una composicion oftalmica preservada.

Country Status (18)

Country Link
EP (1) EP0862414B1 (es)
JP (1) JP4699573B2 (es)
CN (1) CN1092954C (es)
AR (1) AR004952A1 (es)
AT (1) ATE209896T1 (es)
AU (1) AU704925B2 (es)
CY (1) CY2343B1 (es)
CZ (1) CZ291891B6 (es)
DE (1) DE69617726T2 (es)
DK (1) DK0862414T3 (es)
ES (1) ES2169262T3 (es)
HK (1) HK1016510A1 (es)
HU (1) HU224353B1 (es)
PL (1) PL185661B1 (es)
PT (1) PT862414E (es)
TW (1) TW434023B (es)
WO (1) WO1997010805A1 (es)
ZA (1) ZA967827B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4215277B2 (ja) * 1996-08-09 2009-01-28 アルコン ラボラトリーズ,インコーポレイテッド シクロデキストリンを含有する薬学的組成物用防腐剤系
CN1328443A (zh) * 1998-11-23 2001-12-26 宝洁公司 皮肤除臭和卫生消毒组合物
US6656456B2 (en) * 1998-11-23 2003-12-02 The Procter & Gamble Company Skin deodorizing compositions
JP2001125052A (ja) * 1999-10-25 2001-05-11 Lion Corp コンタクトレンズ装着液
JP4880808B2 (ja) * 1999-11-15 2012-02-22 久光製薬株式会社 人工涙液型点眼剤組成物
JP2005521691A (ja) * 2002-02-22 2005-07-21 ファルマシア・コーポレーション シクロデキストリン化合物及び塩化セチルピリジニウムを含有する眼科用抗菌性薬物製剤
TW200400055A (en) 2002-02-22 2004-01-01 Pharmacia Corp Ophthalmic formulation with novel gum composition
CA2479351C (en) * 2002-03-18 2012-05-15 Novartis Ag Topical composition comprising a cyclofructan, a carrier and a drug
KR101121675B1 (ko) * 2002-04-19 2012-03-13 노파르티스 아게 신규 생체적합물질, 그의 제조방법 및 용도
CN100589809C (zh) * 2002-06-13 2010-02-17 诺瓦提斯公司 季铵环糊精化合物
ATE454905T1 (de) * 2004-03-10 2010-01-15 Shimoda Biotech Pty Ltd Stabile injizierbare diclofenac- zubereitungen
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
JP4956981B2 (ja) * 2005-01-05 2012-06-20 大正製薬株式会社 オキシメタゾリン含有水性組成物
WO2006137433A1 (ja) * 2005-06-21 2006-12-28 Wakamoto Pharmaceutical Co., Ltd. レボカバスチンを可溶化させた水性薬剤
AU2012209035B9 (en) * 2006-03-28 2014-05-22 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
JP5823093B2 (ja) 2006-03-28 2015-11-25 ジャヴェリン ファーマシューティカルズ インコーポレイテッド 低投与量のジクロフェナク及びβ−シクロデキストリンの配合物
JP4751482B2 (ja) * 2008-07-22 2011-08-17 株式会社メニコン コンタクトレンズ用液剤
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠(olopatadine)眼用組成物
US9492552B2 (en) * 2011-11-29 2016-11-15 Jurox Pty Ltd Injectable aqueous pharmaceutical compositions comprising a cyclodextrin, a hydrophobic drug, a co-solvent, and a preservative
US10174006B2 (en) * 2013-06-06 2019-01-08 Novartis Ag Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease
CN105076133B (zh) * 2015-08-25 2017-07-25 广州佳伲思抗菌材料有限公司 一种复合型阳离子防霉剂及防霉卡
AU2023214622A1 (en) 2022-02-02 2024-08-08 Oculis Operations Sarl Multidose ophthalmic compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE74750T1 (de) * 1987-09-11 1992-05-15 Syntex Inc Schutzmittel fuer augenzubereitungen.
EP0349487A3 (en) * 1988-06-28 1990-07-04 Ciba-Geigy Ag Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2-phenoxyethyl)-ammonium bromide and methods of using the same
EP0674528A4 (en) * 1992-12-02 1996-06-26 Insite Vision Inc DRUG DELIVERY SYSTEM BASED ON CYCLODEXTRIN AND A POLYMER.
US5494901A (en) * 1993-01-05 1996-02-27 Javitt; Jonathan C. Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent

Also Published As

Publication number Publication date
PT862414E (pt) 2002-05-31
ZA967827B (en) 1997-03-18
CZ80098A3 (cs) 1998-06-17
HUP9900361A2 (hu) 1999-10-28
DE69617726D1 (de) 2002-01-17
HU224353B1 (hu) 2005-08-29
CY2343B1 (en) 2004-02-06
CN1196676A (zh) 1998-10-21
PL324921A1 (en) 1998-06-22
AU704925B2 (en) 1999-05-06
TW434023B (en) 2001-05-16
HK1016510A1 (en) 1999-11-05
PL185661B1 (pl) 2003-06-30
DK0862414T3 (da) 2002-03-25
JPH11512445A (ja) 1999-10-26
AU6987196A (en) 1997-04-09
CZ291891B6 (cs) 2003-06-18
DE69617726T2 (de) 2002-08-08
JP4699573B2 (ja) 2011-06-15
EP0862414A1 (en) 1998-09-09
HUP9900361A3 (en) 1999-11-29
CN1092954C (zh) 2002-10-23
ES2169262T3 (es) 2002-07-01
ATE209896T1 (de) 2001-12-15
WO1997010805A1 (en) 1997-03-27
EP0862414B1 (en) 2001-12-05

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