HUP9900361A2 - Ciklodextrint és kvaterner ammóniumsót tartalmazó szemkészítmények - Google Patents
Ciklodextrint és kvaterner ammóniumsót tartalmazó szemkészítményekInfo
- Publication number
- HUP9900361A2 HUP9900361A2 HU9900361A HUP9900361A HUP9900361A2 HU P9900361 A2 HUP9900361 A2 HU P9900361A2 HU 9900361 A HU9900361 A HU 9900361A HU P9900361 A HUP9900361 A HU P9900361A HU P9900361 A2 HUP9900361 A2 HU P9900361A2
- Authority
- HU
- Hungary
- Prior art keywords
- quaternary ammonium
- compositions containing
- ammonium compounds
- ophthalmic compositions
- preparation
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title 1
- 229940097362 cyclodextrins Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 title 1
- 229920001353 Dextrin Polymers 0.000 abstract 2
- 239000004375 Dextrin Substances 0.000 abstract 2
- -1 alkylene glycol Chemical compound 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 235000019425 dextrin Nutrition 0.000 abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- 230000002335 preservative effect Effects 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgya tartósítőtt szemkészítmény, amely ciklődextrint,kvaterner ammóniűmsót, alkilénglikőlt és gyógyászatilag hatásősvegyületet tartalmaz. A készítményben az alkilénglikől főkőzhatja(vagy legalább fenntartja) a kvaterner ammóniűmsó tartósítószerkéntkifejtett hatékőnyságát, valamint a ciklődextrinnek a gyógyászatilaghatásős vegyület biőlógiai hőzzáférhetőségét főkőzó hatását. Atalálmány szerint előállítőtt szemkészítmény csekély kőncentrációbantartalmazza a tartósítószert vagy az őftalmőlógiás hatóanyagőt. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95810575 | 1995-09-18 | ||
PCT/EP1996/003898 WO1997010805A1 (en) | 1995-09-18 | 1996-09-05 | Ophthalmic compositions containing cyclodextrins and quaternary ammonium compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9900361A2 true HUP9900361A2 (hu) | 1999-10-28 |
HUP9900361A3 HUP9900361A3 (en) | 1999-11-29 |
HU224353B1 HU224353B1 (hu) | 2005-08-29 |
Family
ID=8221792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9900361A HU224353B1 (hu) | 1995-09-18 | 1996-09-05 | Ciklodextrint és kvaterner ammóniumsót tartalmazó szemkészítmények |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0862414B1 (hu) |
JP (1) | JP4699573B2 (hu) |
CN (1) | CN1092954C (hu) |
AR (1) | AR004952A1 (hu) |
AT (1) | ATE209896T1 (hu) |
AU (1) | AU704925B2 (hu) |
CY (1) | CY2343B1 (hu) |
CZ (1) | CZ291891B6 (hu) |
DE (1) | DE69617726T2 (hu) |
DK (1) | DK0862414T3 (hu) |
ES (1) | ES2169262T3 (hu) |
HK (1) | HK1016510A1 (hu) |
HU (1) | HU224353B1 (hu) |
PL (1) | PL185661B1 (hu) |
PT (1) | PT862414E (hu) |
TW (1) | TW434023B (hu) |
WO (1) | WO1997010805A1 (hu) |
ZA (1) | ZA967827B (hu) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2207748T3 (es) * | 1996-08-09 | 2004-06-01 | Alcon Manufacturing Ltd. | Sistemas conservantes para composiciones farmaceuticas que contienen ciclodextrinas. |
CN1328443A (zh) * | 1998-11-23 | 2001-12-26 | 宝洁公司 | 皮肤除臭和卫生消毒组合物 |
US6656456B2 (en) | 1998-11-23 | 2003-12-02 | The Procter & Gamble Company | Skin deodorizing compositions |
JP2001125052A (ja) * | 1999-10-25 | 2001-05-11 | Lion Corp | コンタクトレンズ装着液 |
JP4880808B2 (ja) * | 1999-11-15 | 2012-02-22 | 久光製薬株式会社 | 人工涙液型点眼剤組成物 |
MXPA04008171A (es) | 2002-02-22 | 2004-11-26 | Pharmacia Corp | Formulacion oftalmica con sistema de goma. |
JP2005521691A (ja) * | 2002-02-22 | 2005-07-21 | ファルマシア・コーポレーション | シクロデキストリン化合物及び塩化セチルピリジニウムを含有する眼科用抗菌性薬物製剤 |
EP1487498B1 (en) * | 2002-03-18 | 2009-05-20 | Novartis AG | Topical composition comprising a cyclofructan, a carrier and a drug |
CN1646171B (zh) * | 2002-04-19 | 2010-05-26 | 诺瓦提斯公司 | 新型生物材料、其制备和用途 |
BR0311722A (pt) * | 2002-06-13 | 2005-03-01 | Novartis Ag | Compostos de ciclodextrina com amÈnia quaternizado |
PL1767219T3 (pl) * | 2004-03-10 | 2010-06-30 | Shimoda Biotech Pty Ltd | Trwałe kompozycje diklofenaku do iniekcji |
US9028852B2 (en) | 2004-09-07 | 2015-05-12 | 3M Innovative Properties Company | Cationic antiseptic compositions and methods of use |
JP4956981B2 (ja) * | 2005-01-05 | 2012-06-20 | 大正製薬株式会社 | オキシメタゾリン含有水性組成物 |
JPWO2006137433A1 (ja) * | 2005-06-21 | 2009-01-22 | わかもと製薬株式会社 | レボカバスチンを可溶化させた水性薬剤 |
KR20140038575A (ko) * | 2006-03-28 | 2014-03-28 | 자블린 파머슈티칼스 인코포레이티드 | 저 복용량의 디클로페낙 및 베타-사이클로덱스트린 제형 |
AU2012209035B9 (en) * | 2006-03-28 | 2014-05-22 | Javelin Pharmaceuticals, Inc. | Formulations of low dose diclofenac and beta-cyclodextrin |
JP4751482B2 (ja) * | 2008-07-22 | 2011-08-17 | 株式会社メニコン | コンタクトレンズ用液剤 |
TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠(olopatadine)眼用組成物 |
US9492552B2 (en) * | 2011-11-29 | 2016-11-15 | Jurox Pty Ltd | Injectable aqueous pharmaceutical compositions comprising a cyclodextrin, a hydrophobic drug, a co-solvent, and a preservative |
US10174006B2 (en) | 2013-06-06 | 2019-01-08 | Novartis Ag | Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease |
CN105076133B (zh) * | 2015-08-25 | 2017-07-25 | 广州佳伲思抗菌材料有限公司 | 一种复合型阳离子防霉剂及防霉卡 |
WO2023148231A1 (en) | 2022-02-02 | 2023-08-10 | Oculis SA | Multidose ophthalmic compositions |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO175404C (no) * | 1987-09-11 | 1994-10-12 | Syntex Inc | Fremgangsmåte for fremstilling av et öyepreparat og konserveringsmiddelsystem for et slikt preparat |
IL90680A (en) * | 1988-06-28 | 1994-04-12 | Ciba Geigy Ag | Poor solutions containing dodecyl (dimethyl) 2-phenoxyethyl (ammonium brocide and ATDE and methods of use) |
EP0674528A4 (en) * | 1992-12-02 | 1996-06-26 | Insite Vision Inc | DRUG DELIVERY SYSTEM BASED ON CYCLODEXTRIN AND A POLYMER. |
US5494901A (en) * | 1993-01-05 | 1996-02-27 | Javitt; Jonathan C. | Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent |
-
1996
- 1996-02-07 TW TW085101497A patent/TW434023B/zh not_active IP Right Cessation
- 1996-09-05 ES ES96931025T patent/ES2169262T3/es not_active Expired - Lifetime
- 1996-09-05 PL PL96324921A patent/PL185661B1/pl unknown
- 1996-09-05 JP JP51235297A patent/JP4699573B2/ja not_active Expired - Lifetime
- 1996-09-05 PT PT96931025T patent/PT862414E/pt unknown
- 1996-09-05 AT AT96931025T patent/ATE209896T1/de active
- 1996-09-05 CZ CZ1998800A patent/CZ291891B6/cs not_active IP Right Cessation
- 1996-09-05 AU AU69871/96A patent/AU704925B2/en not_active Expired
- 1996-09-05 EP EP96931025A patent/EP0862414B1/en not_active Expired - Lifetime
- 1996-09-05 DE DE69617726T patent/DE69617726T2/de not_active Expired - Lifetime
- 1996-09-05 HU HU9900361A patent/HU224353B1/hu active IP Right Grant
- 1996-09-05 WO PCT/EP1996/003898 patent/WO1997010805A1/en active IP Right Grant
- 1996-09-05 CN CN96197051A patent/CN1092954C/zh not_active Expired - Lifetime
- 1996-09-05 DK DK96931025T patent/DK0862414T3/da active
- 1996-09-16 AR ARP960104361A patent/AR004952A1/es unknown
- 1996-09-17 ZA ZA967827A patent/ZA967827B/xx unknown
-
1999
- 1999-04-21 HK HK99101735A patent/HK1016510A1/xx not_active IP Right Cessation
-
2003
- 2003-04-30 CY CY0300036A patent/CY2343B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CZ291891B6 (cs) | 2003-06-18 |
DE69617726T2 (de) | 2002-08-08 |
DK0862414T3 (da) | 2002-03-25 |
TW434023B (en) | 2001-05-16 |
AU6987196A (en) | 1997-04-09 |
HK1016510A1 (en) | 1999-11-05 |
PL185661B1 (pl) | 2003-06-30 |
PT862414E (pt) | 2002-05-31 |
CN1092954C (zh) | 2002-10-23 |
CN1196676A (zh) | 1998-10-21 |
ZA967827B (en) | 1997-03-18 |
EP0862414B1 (en) | 2001-12-05 |
EP0862414A1 (en) | 1998-09-09 |
CZ80098A3 (cs) | 1998-06-17 |
AR004952A1 (es) | 1999-04-07 |
PL324921A1 (en) | 1998-06-22 |
JPH11512445A (ja) | 1999-10-26 |
WO1997010805A1 (en) | 1997-03-27 |
CY2343B1 (en) | 2004-02-06 |
JP4699573B2 (ja) | 2011-06-15 |
DE69617726D1 (de) | 2002-01-17 |
ES2169262T3 (es) | 2002-07-01 |
HU224353B1 (hu) | 2005-08-29 |
HUP9900361A3 (en) | 1999-11-29 |
ATE209896T1 (de) | 2001-12-15 |
AU704925B2 (en) | 1999-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20050705 |