AP672A - Clavulanic acid extraction process. - Google Patents

Clavulanic acid extraction process. Download PDF

Info

Publication number
AP672A
AP672A APAP/P/1997/001022A AP9701022A AP672A AP 672 A AP672 A AP 672A AP 9701022 A AP9701022 A AP 9701022A AP 672 A AP672 A AP 672A
Authority
AP
ARIPO
Prior art keywords
phase
solute
organic solvent
salt
process according
Prior art date
Application number
APAP/P/1997/001022A
Other languages
English (en)
Other versions
AP9701022A0 (en
Inventor
Simon Ruddick
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AP9701022A0 publication Critical patent/AP9701022A0/xx
Application granted granted Critical
Publication of AP672A publication Critical patent/AP672A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
APAP/P/1997/001022A 1995-01-19 1996-01-17 Clavulanic acid extraction process. AP672A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9500977.5A GB9500977D0 (en) 1995-01-19 1995-01-19 Novel process
PCT/EP1996/000270 WO1996022296A1 (en) 1995-01-19 1996-01-17 Clavulanic acid extraction process

Publications (2)

Publication Number Publication Date
AP9701022A0 AP9701022A0 (en) 1997-07-31
AP672A true AP672A (en) 1998-09-09

Family

ID=10768206

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/001022A AP672A (en) 1995-01-19 1996-01-17 Clavulanic acid extraction process.

Country Status (31)

Country Link
US (1) US6172221B1 (da)
EP (1) EP0804441B1 (da)
JP (1) JP4111998B2 (da)
KR (1) KR100446199B1 (da)
CN (1) CN1105724C (da)
AP (1) AP672A (da)
AT (1) ATE261976T1 (da)
BG (1) BG63308B1 (da)
BR (1) BR9606919A (da)
CA (1) CA2210748C (da)
CZ (1) CZ294581B6 (da)
DE (1) DE69631878T2 (da)
DK (1) DK0804441T3 (da)
EA (1) EA000277B1 (da)
ES (1) ES2217302T3 (da)
FI (1) FI113776B (da)
GB (1) GB9500977D0 (da)
HK (1) HK1004134A1 (da)
HU (1) HU228768B1 (da)
MX (1) MX9705498A (da)
NO (1) NO317281B1 (da)
NZ (1) NZ300604A (da)
OA (1) OA10501A (da)
PL (1) PL184468B1 (da)
PT (1) PT804441E (da)
RO (1) RO115956B1 (da)
SK (1) SK284484B6 (da)
TR (1) TR199700665T1 (da)
UA (1) UA45380C2 (da)
WO (1) WO1996022296A1 (da)
ZA (1) ZA96392B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9500977D0 (en) * 1995-01-19 1995-03-08 Smithkline Beecham Plc Novel process
US10624899B2 (en) 2016-07-14 2020-04-21 Achaogen, Inc. Combination products for the treatment of bacterial infections and methods of producing or dosing of same
WO2020176806A1 (en) * 2019-02-27 2020-09-03 3-Delta, Inc. Compositions that contain lipophilic plant material and surfactant, and related methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026044A1 (en) * 1979-08-24 1981-04-01 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
EP0153843A2 (en) * 1984-02-23 1985-09-04 United Kingdom Atomic Energy Authority Improvements in and relating to fluidic contactors
WO1996022296A1 (en) * 1995-01-19 1996-07-25 Smithkline Beecham P.L.C. Clavulanic acid extraction process

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
GB9401969D0 (en) 1994-02-02 1994-03-30 Smithkline Beecham Plc Process
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026044A1 (en) * 1979-08-24 1981-04-01 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
EP0153843A2 (en) * 1984-02-23 1985-09-04 United Kingdom Atomic Energy Authority Improvements in and relating to fluidic contactors
WO1996022296A1 (en) * 1995-01-19 1996-07-25 Smithkline Beecham P.L.C. Clavulanic acid extraction process

Also Published As

Publication number Publication date
PL321381A1 (en) 1997-12-08
JPH10512557A (ja) 1998-12-02
GB9500977D0 (en) 1995-03-08
EA000277B1 (ru) 1999-02-25
PT804441E (pt) 2004-07-30
NZ300604A (en) 2000-06-23
KR19980701485A (ko) 1998-05-15
ZA96392B (en) 1996-08-29
EA199700121A1 (ru) 1997-12-30
FI973057A (fi) 1997-07-18
HK1004134A1 (en) 1998-11-20
CA2210748A1 (en) 1996-07-25
NO317281B1 (no) 2004-10-04
HU228768B1 (en) 2013-05-28
CZ294581B6 (cs) 2005-02-16
ATE261976T1 (de) 2004-04-15
EP0804441A1 (en) 1997-11-05
HUP9801699A3 (en) 1999-03-01
HUP9801699A2 (hu) 1998-11-30
SK284484B6 (sk) 2005-04-01
FI973057A0 (fi) 1997-07-18
EP0804441B1 (en) 2004-03-17
BR9606919A (pt) 1997-11-11
UA45380C2 (uk) 2002-04-15
TR199700665T1 (xx) 1998-01-21
PL184468B1 (pl) 2002-11-29
DK0804441T3 (da) 2004-07-12
CN1105724C (zh) 2003-04-16
SK96397A3 (en) 1998-02-04
BG63308B1 (bg) 2001-09-28
AP9701022A0 (en) 1997-07-31
MX9705498A (es) 1997-10-31
RO115956B1 (ro) 2000-08-30
US6172221B1 (en) 2001-01-09
CN1179161A (zh) 1998-04-15
CA2210748C (en) 2008-04-01
NO973328L (no) 1997-09-18
ES2217302T3 (es) 2004-11-01
FI113776B (fi) 2004-06-15
NO973328D0 (no) 1997-07-18
DE69631878T2 (de) 2005-02-03
AU4539096A (en) 1996-08-07
WO1996022296A1 (en) 1996-07-25
DE69631878D1 (de) 2004-04-22
CZ225297A3 (en) 1997-12-17
AU706196B2 (en) 1999-06-10
JP4111998B2 (ja) 2008-07-02
BG101768A (en) 1998-10-30
OA10501A (en) 2002-04-24
KR100446199B1 (ko) 2005-08-04

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