AP652A - Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc. - Google Patents

Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc. Download PDF

Info

Publication number
AP652A
AP652A APAP/P/1997/001089A AP9701089A AP652A AP 652 A AP652 A AP 652A AP 9701089 A AP9701089 A AP 9701089A AP 652 A AP652 A AP 652A
Authority
AP
ARIPO
Prior art keywords
cis
amino
zidovudine
pyrimidin
purin
Prior art date
Application number
APAP/P/1997/001089A
Other languages
English (en)
Other versions
AP9701089A0 (en
Inventor
David Walter Barry
Clair Martha Heider St
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP652(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9506490.3A external-priority patent/GB9506490D0/en
Priority claimed from GBGB9506489.5A external-priority patent/GB9506489D0/en
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of AP9701089A0 publication Critical patent/AP9701089A0/xx
Application granted granted Critical
Publication of AP652A publication Critical patent/AP652A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Cephalosporin Compounds (AREA)
APAP/P/1997/001089A 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc. AP652A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9506490.3A GB9506490D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
GBGB9506489.5A GB9506489D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
PCT/EP1996/001352 WO1996030025A1 (en) 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592u89 and 3tc or ftc

Publications (2)

Publication Number Publication Date
AP9701089A0 AP9701089A0 (en) 1997-10-31
AP652A true AP652A (en) 1998-06-19

Family

ID=26306774

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/001089A AP652A (en) 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc.

Country Status (35)

Country Link
US (1) US6417191B1 (ja)
EP (1) EP0817637B1 (ja)
JP (1) JP2954357B2 (ja)
KR (1) KR100542536B1 (ja)
CN (1) CN1103593C (ja)
AP (1) AP652A (ja)
AT (1) ATE220551T1 (ja)
AU (1) AU715213B2 (ja)
BR (3) BRPI9607851B8 (ja)
CA (1) CA2216634C (ja)
CZ (1) CZ295940B6 (ja)
DE (3) DE122005000029I2 (ja)
DK (1) DK0817637T3 (ja)
EA (1) EA000626B3 (ja)
EE (1) EE04047B1 (ja)
ES (1) ES2179193T3 (ja)
FR (1) FR05C0022I2 (ja)
GE (1) GEP20022647B (ja)
HU (1) HU224010B1 (ja)
IL (1) IL117727A (ja)
LU (1) LU91171I2 (ja)
MX (1) MX9707316A (ja)
MY (1) MY115461A (ja)
NL (1) NL300195I2 (ja)
NO (2) NO313787B1 (ja)
NZ (1) NZ306419A (ja)
OA (1) OA10616A (ja)
PL (1) PL187085B1 (ja)
PT (1) PT817637E (ja)
RO (1) RO117995B1 (ja)
SI (1) SI0817637T1 (ja)
SK (1) SK283825B6 (ja)
TR (1) TR199701074T1 (ja)
UA (1) UA60293C2 (ja)
WO (1) WO1996030025A1 (ja)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ333099A (en) * 1996-06-25 2000-06-23 Glaxo Group Ltd synergistic combinations comprising 141W94, zidovudine and 3TC for use in the treatment of HIV
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
TW536403B (en) * 1997-03-24 2003-06-11 Glaxo Group Ltd An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
BR9809127A (pt) * 1997-05-17 2000-08-01 Glaxo Group Ltd Combinação, formulação farmacêutica, processo para o tratamento de uma infecção por hiv em um animal infectado, uso de (-) -(1s,4r)-4-[2-amino-6-(ciclopropil amino)-9h-purin-9-il)-2-ciclopenteno-1-metanol, e, pacote de paciente
AU769660B2 (en) * 1997-05-17 2004-01-29 Glaxo Group Limited Carbocyclic nucleoside hemisulfate and its use in treating viral infections
GB9809213D0 (en) * 1998-04-29 1998-07-01 Glaxo Group Ltd Pharmaceutical compositions
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
CA2374198A1 (en) * 1998-05-29 1999-12-02 Maki Arai Combination therapy for treatment of fiv infection
GB9820417D0 (en) * 1998-09-18 1998-11-11 Glaxo Group Ltd Antiviral combinations
US6432966B2 (en) 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
AP2220A (en) * 2001-05-11 2011-03-24 Cipla Medpro Pty Ltd Pharmaceutical composition.
AR040242A1 (es) * 2002-06-04 2005-03-23 Glaxo Group Ltd Composiciones farmaceuticas
MXPA05007016A (es) 2003-01-14 2005-09-12 Gilead Sciences Inc Composiciones y metodos para terapia antiviral de combinacion.
BRPI0408704A (pt) 2003-03-24 2006-03-07 Hoffmann La Roche benzil-piridazinonas como inibidores de transcriptase reversa
EP1692516B1 (en) 2003-10-24 2010-12-01 Immunaid Pty Ltd Method of therapy
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
WO2007045573A1 (en) 2005-10-19 2007-04-26 F. Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
CN101553483B (zh) 2006-12-13 2013-04-17 弗·哈夫曼-拉罗切有限公司 作为非核苷逆转录酶抑制剂的2-(哌啶-4-基)-4-苯氧基-或苯基氨基-嘧啶衍生物
PL2120878T3 (pl) * 2007-02-09 2015-01-30 Alphapharm Pty Ltd Postać dawkowania zawierająca dwa czynne składniki farmaceutyczne o różnych postaciach fizycznych
WO2010135781A1 (en) 2009-05-27 2010-12-02 Immunaid Pty Ltd Methods of treating diseases
PE20121524A1 (es) 2010-01-27 2012-12-03 Viiv Healthcare Co Combinaciones de compuestos que comprenden inhibidores de la integrasa de vih y otros agentes terapeuticos
HK1220390A1 (zh) 2013-08-29 2017-05-05 Teva Pharmaceutical Industries Ltd. 包括恩曲他滨，替诺福韦，达芦那韦和利托那韦的单位剂型以及包含达芦那韦和利托那韦的单体片剂
CA2942877A1 (en) 2014-04-08 2015-10-15 Nitzan SHAHAR Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir
EP4578865A3 (en) 2014-08-12 2025-07-30 Monash University Lymph directing prodrugs
CA2997106C (en) 2015-09-08 2024-06-04 Monash University Lymph directing prodrugs
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
EP3675838A4 (en) * 2017-08-29 2021-04-21 PureTech LYT, Inc. LIPID PRODRUGS DIRECTED TO THE LYMPHATIC SYSTEM
US11608345B1 (en) 2017-12-19 2023-03-21 Puretech Lyt, Inc. Lipid prodrugs of rapamycin and its analogs and uses thereof
US11304954B2 (en) 2017-12-19 2022-04-19 Puretech Lyt, Inc. Lipid prodrugs of mycophenolic acid and uses thereof
CN115348864A (zh) 2020-02-05 2022-11-15 纯技术Lyt股份有限公司 神经甾体的脂质前药

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015309A1 (en) * 1991-03-06 1992-09-17 The Wellcome Foundation Limited Antiviral nucleoside combination
EP0513917A1 (en) * 1991-05-16 1992-11-19 Glaxo Group Limited Antiviral combinations containing nucleoside analogs
WO1993023021A2 (en) * 1992-05-13 1993-11-25 The Wellcome Foundation Limited Therapeutic combinations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5122517A (en) 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
GB9009861D0 (en) * 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
US5723490A (en) 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
GB9417249D0 (en) 1994-08-26 1994-10-19 Wellcome Found A novel salt
US5869461A (en) 1995-03-16 1999-02-09 Yale University Reducing toxicity of L-nucleosides with D-nucleosides
CZ429398A3 (cs) 1996-06-25 1999-05-12 Glaxo Group Limited Kombinace účinných látek a farmaceutický prostředek
NZ333099A (en) 1996-06-25 2000-06-23 Glaxo Group Ltd synergistic combinations comprising 141W94, zidovudine and 3TC for use in the treatment of HIV
DE10226522A1 (de) 2002-06-14 2003-12-24 Degussa Verwendung von Übergangsmetallkomplexen mit stickstoffhaltigen mehrzähnigen Liganden als Bleichkatalysator und Bleichmittelzusammensetzung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015309A1 (en) * 1991-03-06 1992-09-17 The Wellcome Foundation Limited Antiviral nucleoside combination
EP0513917A1 (en) * 1991-05-16 1992-11-19 Glaxo Group Limited Antiviral combinations containing nucleoside analogs
WO1993023021A2 (en) * 1992-05-13 1993-11-25 The Wellcome Foundation Limited Therapeutic combinations

Also Published As

Publication number Publication date
MY115461A (en) 2003-06-30
ES2179193T3 (es) 2003-01-16
DK0817637T3 (da) 2002-11-11
LU91171I9 (ja) 2018-12-28
CA2216634C (en) 2004-07-20
GEP20022647B (en) 2002-03-25
PL187085B1 (pl) 2004-05-31
JPH10511682A (ja) 1998-11-10
CZ309097A3 (cs) 1998-05-13
RO117995B1 (ro) 2002-12-30
HK1009401A1 (en) 1999-09-10
KR100542536B1 (ko) 2006-03-23
AU715213B2 (en) 2000-01-20
BRPI9612992B1 (pt) 2020-08-04
DE122005000029I1 (de) 2005-10-06
CN1103593C (zh) 2003-03-26
NO2005014I2 (no) 2008-02-11
NO313787B1 (no) 2002-12-02
SK283825B6 (sk) 2004-02-03
WO1996030025A1 (en) 1996-10-03
EE04047B1 (et) 2003-06-16
BRPI9607851B8 (pt) 2019-11-05
NL300195I2 (nl) 2005-11-01
JP2954357B2 (ja) 1999-09-27
DE122005000029I2 (de) 2006-04-27
NO2005014I1 (no) 2005-06-06
NL300195I1 (nl) 2005-08-01
TR199701074T1 (xx) 1998-02-21
MX9707316A (es) 1997-11-29
DE69622386T2 (de) 2003-02-13
DE69622386D1 (de) 2002-08-22
IL117727A0 (en) 1996-07-23
EE9700240A (et) 1998-04-15
EP0817637B1 (en) 2002-07-17
FR05C0022I2 (ja) 2005-10-21
BR9607851B1 (pt) 2009-01-13
ATE220551T1 (de) 2002-08-15
OA10616A (en) 2001-03-15
CZ295940B6 (cs) 2005-12-14
NZ306419A (en) 2000-01-28
PT817637E (pt) 2002-11-29
NO974510D0 (no) 1997-09-29
EA000626B3 (ru) 2016-04-29
SK129597A3 (en) 1998-07-08
HU224010B1 (hu) 2005-04-28
EP0817637A1 (en) 1998-01-14
AP9701089A0 (en) 1997-10-31
FR05C0022I1 (ja) 2005-06-10
CA2216634A1 (en) 1996-10-03
LU91171I2 (fr) 2005-07-04
HUP9801571A2 (hu) 1999-01-28
SI0817637T1 (en) 2002-10-31
US6417191B1 (en) 2002-07-09
NO974510L (no) 1997-09-29
KR19980703420A (ko) 1998-11-05
AU5497296A (en) 1996-10-16
CN1185110A (zh) 1998-06-17
PL322532A1 (en) 1998-02-02
EA199700203A1 (ru) 1998-02-26
EA000626B1 (ru) 1999-12-29
HUP9801571A3 (en) 2001-04-28
IL117727A (en) 1999-11-30
BR9607851A (pt) 1998-07-21
UA60293C2 (uk) 2003-10-15

Similar Documents

Publication Publication Date Title
AP652A (en) Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc.
AU727983B2 (en) Combinations comprising VX478, zidovudine, FTC and/or 3TC for use in the treatment of HIV
EP1113802B1 (en) Antiviral combinations of lamivudine and adefovir
US6486136B1 (en) Combinations comprising VX478, zidovudine and/or 1592U89 for use in the treatment of HIV
US6432966B2 (en) Antiviral combinations
WO2000016779A1 (en) Antiviral combinations comprising lamivudine and abacavir
WO2000018383A2 (en) Antiviral combinations comprising (s)-2- ethyl-7- fluoro-3- oxo-3,4- dihydro-2h- quinoxaline-1- carboxylic acid isopropyl ester
AU8017298A (en) Antiviral combinations containing the carbocyclic nucleoside 1592u89
WO2000016754A2 (en) Antiviral combinations comprising lamivudine and lobucavir
HK1035670B (en) Antiviral combinations of lamivudine and adefovir