AP652A - Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc. - Google Patents

Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc. Download PDF

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Publication number
AP652A
AP652A APAP/P/1997/001089A AP9701089A AP652A AP 652 A AP652 A AP 652A AP 9701089 A AP9701089 A AP 9701089A AP 652 A AP652 A AP 652A
Authority
AP
ARIPO
Prior art keywords
cis
amino
zidovudine
pyrimidin
purin
Prior art date
Application number
APAP/P/1997/001089A
Other languages
English (en)
Other versions
AP9701089A0 (en
Inventor
David Walter Barry
Clair Martha Heider St
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP652(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9506490.3A external-priority patent/GB9506490D0/en
Priority claimed from GBGB9506489.5A external-priority patent/GB9506489D0/en
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of AP9701089A0 publication Critical patent/AP9701089A0/xx
Application granted granted Critical
Publication of AP652A publication Critical patent/AP652A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
APAP/P/1997/001089A 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc. AP652A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9506490.3A GB9506490D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
GBGB9506489.5A GB9506489D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
PCT/EP1996/001352 WO1996030025A1 (fr) 1995-03-30 1996-03-28 Combinaisons synergiques de zidovudine, 1592u89 et 3tc ou ftc

Publications (2)

Publication Number Publication Date
AP9701089A0 AP9701089A0 (en) 1997-10-31
AP652A true AP652A (en) 1998-06-19

Family

ID=26306774

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/001089A AP652A (en) 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592U89 and 3tc or Ftc.

Country Status (36)

Country Link
US (1) US6417191B1 (fr)
EP (1) EP0817637B1 (fr)
JP (1) JP2954357B2 (fr)
KR (1) KR100542536B1 (fr)
CN (1) CN1103593C (fr)
AP (1) AP652A (fr)
AT (1) ATE220551T1 (fr)
AU (1) AU715213B2 (fr)
BR (3) BRPI9607851B8 (fr)
CA (1) CA2216634C (fr)
CZ (1) CZ295940B6 (fr)
DE (3) DE69622386T2 (fr)
DK (1) DK0817637T3 (fr)
EA (1) EA000626B3 (fr)
EE (1) EE04047B1 (fr)
ES (1) ES2179193T3 (fr)
FR (1) FR05C0022I2 (fr)
GE (1) GEP20022647B (fr)
HK (1) HK1009401A1 (fr)
HU (1) HU224010B1 (fr)
IL (1) IL117727A (fr)
LU (1) LU91171I2 (fr)
MX (1) MX9707316A (fr)
MY (1) MY115461A (fr)
NL (1) NL300195I2 (fr)
NO (2) NO313787B1 (fr)
NZ (1) NZ306419A (fr)
OA (1) OA10616A (fr)
PL (1) PL187085B1 (fr)
PT (1) PT817637E (fr)
RO (1) RO117995B1 (fr)
SI (1) SI0817637T1 (fr)
SK (1) SK283825B6 (fr)
TR (1) TR199701074T1 (fr)
UA (1) UA60293C2 (fr)
WO (1) WO1996030025A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544961B1 (en) 1996-06-25 2003-04-08 Smithkline Beecham Corporation Combinations comprising VX478, zidovudine, FTC and/or 3TC for use in the treatments of HIV
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
TW536403B (en) * 1997-03-24 2003-06-11 Glaxo Group Ltd An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy
AU769660B2 (en) * 1997-05-17 2004-01-29 Glaxo Group Limited Carbocyclic nucleoside hemisulfate and its use in treating viral infections
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
EP0979082A1 (fr) * 1997-05-17 2000-02-16 Glaxo Group Limited Combinaisons antivirales contenant le nucleoside carbocyclique 1592u89
GB9809213D0 (en) * 1998-04-29 1998-07-01 Glaxo Group Ltd Pharmaceutical compositions
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
AU4219799A (en) * 1998-05-29 1999-12-13 University Of Florida Combination therapy for treatment of fiv infection
GB9820417D0 (en) * 1998-09-18 1998-11-11 Glaxo Group Ltd Antiviral combinations
US6432966B2 (en) 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
AP2220A (en) * 2001-05-11 2011-03-24 Cipla Medpro Pty Ltd Pharmaceutical composition.
AR040242A1 (es) * 2002-06-04 2005-03-23 Glaxo Group Ltd Composiciones farmaceuticas
DK1583542T3 (da) 2003-01-14 2008-09-22 Gilead Sciences Inc Sammensætninger og fremgangsmåder til antiviral kombinationsterapi
CN100469769C (zh) 2003-03-24 2009-03-18 弗·哈夫曼-拉罗切有限公司 作为逆转录酶抑制剂的苄基-哒嗪酮
DE602004030369D1 (de) 2003-10-24 2011-01-13 Immunaid Pty Ltd Therapieverfahren
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
AU2006303368B2 (en) 2005-10-19 2011-05-26 F. Hoffmann-La Roche Ag Non-Nucleoside Reverse Transcriptase Inhibitors
KR101475091B1 (ko) 2006-12-13 2014-12-22 에프. 호프만-라 로슈 아게 비뉴클레오시드 역전사 효소 억제제로서 2-(피페리딘-4-일)-4-페녹시- 또는 페닐아미노-피리미딘 유도체
US9095519B2 (en) * 2007-02-09 2015-08-04 Alphapharm Pty Ltd Dosage form containing two or more active pharmaceutical ingredients in different physical forms
EP2982978A1 (fr) 2009-05-27 2016-02-10 Immunaid Pty Ltd Procédés de traitement de maladies
EA025176B1 (ru) 2010-01-27 2016-11-30 Вайв Хелткер Компани Комбинация для лечения вич-инфекции
CA2918707A1 (fr) 2013-08-29 2015-03-05 Teva Pharmaceuticals Industries Ltd. Forme pharmaceutique unitaire comprenant de l'emtricitabine, du tenofovir, du darunavir et du ritonavir et un comprime monolithique comprenant du darunavir et du ritonavir
AU2015245217A1 (en) 2014-04-08 2016-10-13 Teva Pharmaceutical Industries Ltd. Unit dosage form comprising Emtricitabine, Tenofovir, Darunavir and Ritonavir
WO2016023082A1 (fr) 2014-08-12 2016-02-18 Monash University Promédicaments de transport vers le système lymphatique
EP3347340A4 (fr) 2015-09-08 2019-01-23 Monash University Promédicaments ciblant la lymphe
EP4306524A3 (fr) * 2017-08-29 2024-09-11 PureTech LYT, Inc. Promédicaments lipidiques dirigeant le système lymphatique
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
US11304954B2 (en) 2017-12-19 2022-04-19 Puretech Lyt, Inc. Lipid prodrugs of mycophenolic acid and uses thereof
US11608345B1 (en) 2017-12-19 2023-03-21 Puretech Lyt, Inc. Lipid prodrugs of rapamycin and its analogs and uses thereof
CN115348864A (zh) 2020-02-05 2022-11-15 纯技术Lyt股份有限公司 神经甾体的脂质前药

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015309A1 (fr) * 1991-03-06 1992-09-17 The Wellcome Foundation Limited Combinaison antivirale de nucleosides
EP0513917A1 (fr) * 1991-05-16 1992-11-19 Glaxo Group Limited Combination antivirale contenant des analogues de nucléosides
WO1993023021A2 (fr) * 1992-05-13 1993-11-25 The Wellcome Foundation Limited Combinaisons therapeutiques

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5122517A (en) 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
GB9009861D0 (en) * 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
US5723490A (en) 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
GB9417249D0 (en) 1994-08-26 1994-10-19 Wellcome Found A novel salt
US5869461A (en) 1995-03-16 1999-02-09 Yale University Reducing toxicity of L-nucleosides with D-nucleosides
PE87398A1 (es) 1996-06-25 1999-01-15 Glaxo Group Ltd Combinaciones antivirales
US6544961B1 (en) 1996-06-25 2003-04-08 Smithkline Beecham Corporation Combinations comprising VX478, zidovudine, FTC and/or 3TC for use in the treatments of HIV
DE10226522A1 (de) * 2002-06-14 2003-12-24 Degussa Verwendung von Übergangsmetallkomplexen mit stickstoffhaltigen mehrzähnigen Liganden als Bleichkatalysator und Bleichmittelzusammensetzung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015309A1 (fr) * 1991-03-06 1992-09-17 The Wellcome Foundation Limited Combinaison antivirale de nucleosides
EP0513917A1 (fr) * 1991-05-16 1992-11-19 Glaxo Group Limited Combination antivirale contenant des analogues de nucléosides
WO1993023021A2 (fr) * 1992-05-13 1993-11-25 The Wellcome Foundation Limited Combinaisons therapeutiques

Also Published As

Publication number Publication date
FR05C0022I1 (fr) 2005-06-10
CA2216634A1 (fr) 1996-10-03
CA2216634C (fr) 2004-07-20
NO974510L (no) 1997-09-29
KR19980703420A (ko) 1998-11-05
SI0817637T1 (en) 2002-10-31
HK1009401A1 (en) 1999-09-10
IL117727A0 (en) 1996-07-23
NZ306419A (en) 2000-01-28
PT817637E (pt) 2002-11-29
MX9707316A (es) 1997-11-29
US6417191B1 (en) 2002-07-09
RO117995B1 (ro) 2002-12-30
NO2005014I1 (no) 2005-06-06
BRPI9607851B8 (pt) 2019-11-05
HUP9801571A2 (hu) 1999-01-28
HU224010B1 (hu) 2005-04-28
JP2954357B2 (ja) 1999-09-27
CZ309097A3 (cs) 1998-05-13
NL300195I2 (nl) 2005-11-01
AU5497296A (en) 1996-10-16
OA10616A (en) 2001-03-15
AP9701089A0 (en) 1997-10-31
GEP20022647B (en) 2002-03-25
EA000626B3 (ru) 2016-04-29
AU715213B2 (en) 2000-01-20
EE9700240A (et) 1998-04-15
PL322532A1 (en) 1998-02-02
NL300195I1 (nl) 2005-08-01
TR199701074T1 (xx) 1998-02-21
ES2179193T3 (es) 2003-01-16
BRPI9612992B1 (pt) 2020-08-04
DE69622386D1 (de) 2002-08-22
EA000626B1 (ru) 1999-12-29
MY115461A (en) 2003-06-30
BR9607851A (pt) 1998-07-21
EP0817637B1 (fr) 2002-07-17
CN1103593C (zh) 2003-03-26
BR9607851B1 (pt) 2009-01-13
KR100542536B1 (ko) 2006-03-23
SK129597A3 (en) 1998-07-08
NO974510D0 (no) 1997-09-29
DE122005000029I1 (de) 2005-10-06
NO313787B1 (no) 2002-12-02
CN1185110A (zh) 1998-06-17
UA60293C2 (uk) 2003-10-15
DE69622386T2 (de) 2003-02-13
EP0817637A1 (fr) 1998-01-14
ATE220551T1 (de) 2002-08-15
DK0817637T3 (da) 2002-11-11
IL117727A (en) 1999-11-30
NO2005014I2 (no) 2008-02-11
LU91171I2 (fr) 2005-07-04
LU91171I9 (fr) 2018-12-28
HUP9801571A3 (en) 2001-04-28
DE122005000029I2 (de) 2006-04-27
EE04047B1 (et) 2003-06-16
EA199700203A1 (ru) 1998-02-26
PL187085B1 (pl) 2004-05-31
FR05C0022I2 (fr) 2005-10-21
SK283825B6 (sk) 2004-02-03
WO1996030025A1 (fr) 1996-10-03
JPH10511682A (ja) 1998-11-10
CZ295940B6 (cs) 2005-12-14

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