AP506A - Insecticidal substituted-2,4-diaminoquinazolines. - Google Patents

Insecticidal substituted-2,4-diaminoquinazolines. Download PDF

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Publication number
AP506A
AP506A APAP/P/1994/000620A AP9400620A AP506A AP 506 A AP506 A AP 506A AP 9400620 A AP9400620 A AP 9400620A AP 506 A AP506 A AP 506A
Authority
AP
ARIPO
Prior art keywords
hydrogen
substituted
phenyl
grams
alkyl
Prior art date
Application number
APAP/P/1994/000620A
Other languages
English (en)
Other versions
AP9400620A0 (en
Inventor
11 Robert Neil HENRIE
Clinton Joseph Peake
Thomas Gerard Cullen
Albert C Lew
Munirathnam Krishnappa Chaguturu
Partha Sarathi Ray
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of AP9400620A0 publication Critical patent/AP9400620A0/xx
Application granted granted Critical
Publication of AP506A publication Critical patent/AP506A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
APAP/P/1994/000620A 1993-02-18 1994-02-16 Insecticidal substituted-2,4-diaminoquinazolines. AP506A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1938993A 1993-02-18 1993-02-18
US14949193A 1993-11-09 1993-11-09

Publications (2)

Publication Number Publication Date
AP9400620A0 AP9400620A0 (en) 1994-04-30
AP506A true AP506A (en) 1996-07-18

Family

ID=26692173

Family Applications (2)

Application Number Title Priority Date Filing Date
APAP/P/1994/000620A AP506A (en) 1993-02-18 1994-02-16 Insecticidal substituted-2,4-diaminoquinazolines.
APAP/P/1996/000796A AP507A (en) 1993-02-18 1996-02-16 Novel insecticidal 2,4-diaminoquinazolines.

Family Applications After (1)

Application Number Title Priority Date Filing Date
APAP/P/1996/000796A AP507A (en) 1993-02-18 1996-02-16 Novel insecticidal 2,4-diaminoquinazolines.

Country Status (10)

Country Link
US (3) US5534518A (fr)
EP (1) EP0684824A4 (fr)
AP (2) AP506A (fr)
AU (1) AU6298694A (fr)
IL (1) IL108630A0 (fr)
MA (1) MA23116A1 (fr)
MX (1) MX9401249A (fr)
TN (1) TNSN94014A1 (fr)
TW (1) TW315298B (fr)
WO (1) WO1994018980A1 (fr)

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JP4370002B2 (ja) * 1997-08-08 2009-11-25 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
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US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
ES2250425T3 (es) * 2000-06-30 2006-04-16 Basf Aktiengesellschaft Procedimiento para la obtencion de derivados de la 4-bromo-anilina.
PE20020506A1 (es) * 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
EP1366028A1 (fr) * 2001-02-28 2003-12-03 Melacure Therapeutics AB Esters de diaminoquinazoline esters destines a etre utilises avec des inhibiteurs de la dihydrofolate reductase
GB0124931D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
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GB0124936D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124939D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
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GB0124932D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
ATE485275T1 (de) 2002-02-12 2010-11-15 Glaxosmithkline Llc Nicotinamide und deren verwendung als p38 inhibitoren
GB0217757D0 (en) 2002-07-31 2002-09-11 Glaxo Group Ltd Novel compounds
WO2004069255A2 (fr) * 2003-02-04 2004-08-19 Mcmaster University Procede d'inhibition de la dihydrofolate reductase ; essai de criblage d'identification de nouveaux agents therapeutiques et leurs cibles cellulaires
GB0308186D0 (en) * 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
GB0308185D0 (en) * 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
GB0308201D0 (en) * 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
CN1774425A (zh) * 2003-04-16 2006-05-17 霍夫曼-拉罗奇有限公司 喹唑啉化合物
US20040248880A1 (en) * 2003-04-25 2004-12-09 Jacobsen Eric Jon 1,2,3,4,5,6-Hexahydroazepino[4,5-B]indoles containing arylsulfones at the 9-position
US7465738B2 (en) * 2003-06-16 2008-12-16 Vertex Pharmaceuticals Incorporated Compounds useful as promoters of SMN2
GB0318814D0 (en) * 2003-08-11 2003-09-10 Smithkline Beecham Corp Novel compounds
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
GB0402143D0 (en) * 2004-01-30 2004-03-03 Smithkline Beecham Corp Novel compounds
JP5001150B2 (ja) * 2004-06-08 2012-08-15 ファミリーズ オブ スパイナル マスキュラー アトロフィー 脊髄性筋萎縮症のための２，４−ジアミノキナゾリン
WO2006029385A2 (fr) * 2004-09-08 2006-03-16 Chelsea Therapeutics, Inc. Antifoliques metaboliquement inertes utiles dans le traitement des maladies liees a la proliferation cellulaire anormale et a une inflammation
US20070054916A1 (en) * 2004-10-01 2007-03-08 Amgen Inc. Aryl nitrogen-containing bicyclic compounds and methods of use
US20080051416A1 (en) * 2004-10-05 2008-02-28 Smithkline Beecham Corporation Novel Compounds
WO2006050843A1 (fr) * 2004-11-09 2006-05-18 F. Hoffmann-La Roche Ag Composes aminoquinazolines
GB0512429D0 (en) * 2005-06-17 2005-07-27 Smithkline Beecham Corp Novel compound
WO2008009078A2 (fr) * 2006-07-20 2008-01-24 Gilead Sciences, Inc. Dérivés de la quinazoline tri-substitués en 4,6-dl et en 2,4,6 utilisables pour traiter les infections virales
CA2659376C (fr) 2006-08-01 2014-10-14 Jasbir Singh 2,4-diaminoquinazolines contre l'amyotrophie spinale
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JP2011516561A (ja) * 2008-04-07 2011-05-26 チェルシー・セラピューティクス，インコーポレイテッド 抗葉酸化合物の結晶塩形およびその製造方法
DE102008022221A1 (de) 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitoren der humanen Aldosteronsynthase CYP11B2
WO2011005832A1 (fr) * 2009-07-08 2011-01-13 Chelsea Therapeutics, Inc. Polymorphes cristallins stables du sel de dipotassium de l’acide (s) -2- {4- [2- (2, 4-diamino-quinazolin-6-yle) -éthyle] -benzoylamino} -4-méthylène-pentane dioïque
JP2013510163A (ja) * 2009-11-06 2013-03-21 チェルシー・セラピューティクス，インコーポレイテッド 酵素阻害化合物
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US8835445B2 (en) 2010-06-02 2014-09-16 Trius Therapeutics, Inc. Dihydrofolate reductase inhibitors
WO2012078708A1 (fr) 2010-12-07 2012-06-14 Chelsea Therapeutics, Inc. Combinaison comprenant du méthotrexate et un composé d'antifolate
CN102552271B (zh) 2010-12-09 2014-08-06 中国科学院上海药物研究所 一类喹唑啉类化合物在制备抗黄病毒科病毒的药物中的用途
GB201104153D0 (en) * 2011-03-11 2011-04-27 Glaxo Group Ltd Novel compounds
TW201311149A (zh) * 2011-06-24 2013-03-16 Ishihara Sangyo Kaisha 有害生物防治劑
EA035093B1 (ru) 2015-03-04 2020-04-27 Джилид Сайэнс, Инк. 4,6-диаминопиридо[3,2-d]пиримидиновые соединения, модулирующие toll-подобные рецепторы
ES2826748T3 (es) 2016-09-02 2021-05-19 Gilead Sciences Inc Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll
ES2906581T3 (es) 2016-09-02 2022-04-19 Gilead Sciences Inc Compuestos moduladores de los receptores tipo Toll
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法
EP4457229A1 (fr) 2021-12-30 2024-11-06 Byondis B.V. Médicaments de liaison antifolate et conjugués anticorps-médicament

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Also Published As

Publication number Publication date
US5534518A (en) 1996-07-09
US5616718A (en) 1997-04-01
WO1994018980A1 (fr) 1994-09-01
EP0684824A1 (fr) 1995-12-06
AP9400620A0 (en) 1994-04-30
AU6298694A (en) 1994-09-14
IL108630A0 (en) 1994-05-30
TW315298B (fr) 1997-09-11
MA23116A1 (fr) 1994-10-01
EP0684824A4 (fr) 1996-02-14
AP507A (en) 1996-07-18
US5874579A (en) 1999-02-23
TNSN94014A1 (fr) 1995-04-25
AP9600796A0 (en) 1996-04-30
MX9401249A (es) 1994-08-31

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