AP2514A - HIV reverse transcriptase inhibitors - Google Patents

HIV reverse transcriptase inhibitors

Info

Publication number
AP2514A
AP2514A AP2009004759A AP2009004759A AP2514A AP 2514 A AP2514 A AP 2514A AP 2009004759 A AP2009004759 A AP 2009004759A AP 2009004759 A AP2009004759 A AP 2009004759A AP 2514 A AP2514 A AP 2514A
Authority
AP
ARIPO
Prior art keywords
reverse transcriptase
transcriptase inhibitors
hiv reverse
hiv
inhibitors
Prior art date
Application number
AP2009004759A
Other languages
English (en)
Other versions
AP2009004759A0 (en
Inventor
Hongyan Guo
Choung U Kim
Young Lee Iii
Original Assignee
Korea Res Inst Chem Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Res Inst Chem Tech filed Critical Korea Res Inst Chem Tech
Publication of AP2009004759A0 publication Critical patent/AP2009004759A0/xx
Application granted granted Critical
Publication of AP2514A publication Critical patent/AP2514A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AP2009004759A 2006-07-24 2007-07-24 HIV reverse transcriptase inhibitors AP2514A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83280606P 2006-07-24 2006-07-24
PCT/US2007/016703 WO2008016522A2 (en) 2006-07-24 2007-07-24 Hiv reverse transcriptase inhibitors

Publications (2)

Publication Number Publication Date
AP2009004759A0 AP2009004759A0 (en) 2009-02-28
AP2514A true AP2514A (en) 2012-11-23

Family

ID=38997642

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2009004759A AP2514A (en) 2006-07-24 2007-07-24 HIV reverse transcriptase inhibitors

Country Status (18)

Country Link
US (2) US8106064B2 (de)
EP (1) EP2044037A2 (de)
JP (1) JP2009544710A (de)
KR (2) KR20110089463A (de)
CN (1) CN101495461A (de)
AP (1) AP2514A (de)
AU (1) AU2007281604A1 (de)
BR (1) BRPI0714880A2 (de)
CA (1) CA2658479A1 (de)
EA (1) EA200900213A1 (de)
HR (1) HRP20090114A2 (de)
IL (1) IL196675A0 (de)
MX (1) MX2009000871A (de)
NO (1) NO20090835L (de)
NZ (1) NZ573793A (de)
SG (1) SG174016A1 (de)
UA (1) UA95955C2 (de)
WO (1) WO2008016522A2 (de)

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EP2640705A2 (de) 2010-11-15 2013-09-25 Katholieke Universiteit Leuven Neue antivirale verbindungen
CN107266498B (zh) 2011-10-07 2023-10-03 吉利德科学公司 制备抗病毒核苷酸类似物的方法
CA3131037A1 (en) 2011-11-30 2013-06-06 Emory University Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections
CA2863632C (en) 2012-01-19 2017-07-11 The Johns Hopkins University Nanoparticle formulations with enhanced mucosal penetration
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CA2914178C (en) 2013-01-07 2023-06-13 University Of Southern California Deoxyuridine triphosphatase inhibitors
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JP6513095B2 (ja) 2014-01-03 2019-05-15 ユニバーシティ オブ サザン カリフォルニア ヘテロ原子含有デオキシウリジントリホスファターゼ阻害剤
WO2015127389A1 (en) 2014-02-23 2015-08-27 The Johns Hopkins University Hypotonic enema formulations and methods of use
RS62434B1 (sr) 2014-12-26 2021-11-30 Univ Emory Antivirusni n4-hidroksicitidin derivati
EP3250184A1 (de) 2015-01-27 2017-12-06 The Johns Hopkins University Hypotone hydrogelformulierungen für den verbesserten transport von wirkstoffen an schleimhautoberflächen
WO2017006270A1 (en) 2015-07-08 2017-01-12 University Of Southern California Deoxyuridine triphosphatase inhibitors
WO2017006271A1 (en) 2015-07-08 2017-01-12 University Of Southern California Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
WO2017006282A1 (en) 2015-07-08 2017-01-12 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
WO2017006283A1 (en) 2015-07-08 2017-01-12 Cv6 Therapeutics (Ni) Limited Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
US11168059B2 (en) 2016-11-23 2021-11-09 Cv6 Therapeutics (Ni) Limited Amino sulfonyl compounds
US11174271B2 (en) 2016-11-23 2021-11-16 Cv6 Therapeutics (Ni) Limited 6-membered uracil isosteres
WO2018098208A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Nitrogen ring linked deoxyuridine triphosphatase inhibitors
WO2018098207A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
WO2018098206A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US11247984B2 (en) 2017-01-05 2022-02-15 Cv6 Therapeutics (Ni) Limited Uracil containing compounds
CA3056563C (en) * 2017-03-17 2023-03-14 Meiji Seika Pharma Co., Ltd. Plant disease control agent
CN111372592A (zh) 2017-12-07 2020-07-03 埃默里大学 N4-羟基胞苷及衍生物和与其相关的抗病毒用途
CN115536596A (zh) * 2022-11-08 2022-12-30 巨鑫生物制药股份有限公司 一种acc007中间体的制备方法

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Also Published As

Publication number Publication date
AU2007281604A1 (en) 2008-02-07
UA95955C2 (ru) 2011-09-26
AP2009004759A0 (en) 2009-02-28
SG174016A1 (en) 2011-09-29
US8106064B2 (en) 2012-01-31
US20100034827A1 (en) 2010-02-11
EA200900213A1 (ru) 2009-06-30
EP2044037A2 (de) 2009-04-08
CN101495461A (zh) 2009-07-29
HRP20090114A2 (hr) 2010-03-31
JP2009544710A (ja) 2009-12-17
KR20090040449A (ko) 2009-04-24
IL196675A0 (en) 2009-11-18
WO2008016522A2 (en) 2008-02-07
MX2009000871A (es) 2009-05-08
CA2658479A1 (en) 2008-02-07
US20080070920A1 (en) 2008-03-20
WO2008016522A3 (en) 2008-12-11
NZ573793A (en) 2012-01-12
KR20110089463A (ko) 2011-08-08
NO20090835L (no) 2009-04-23
BRPI0714880A2 (pt) 2013-05-21

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