AP2015008734A0 - Cdc7 inhibitors - Google Patents

Cdc7 inhibitors

Info

Publication number
AP2015008734A0
AP2015008734A0 AP2015008734A AP2015008734A AP2015008734A0 AP 2015008734 A0 AP2015008734 A0 AP 2015008734A0 AP 2015008734 A AP2015008734 A AP 2015008734A AP 2015008734 A AP2015008734 A AP 2015008734A AP 2015008734 A0 AP2015008734 A0 AP 2015008734A0
Authority
AP
ARIPO
Prior art keywords
cdc7 inhibitors
cdc7
inhibitors
Prior art date
Application number
AP2015008734A
Other languages
English (en)
Inventor
Timothy Andrew Woods
Robert Dean Dally
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AP2015008734A0 publication Critical patent/AP2015008734A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
AP2015008734A 2013-03-14 2014-03-07 Cdc7 inhibitors AP2015008734A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361782798P 2013-03-14 2013-03-14
US201361789108P 2013-03-15 2013-03-15
PCT/US2014/021466 WO2014143601A1 (en) 2013-03-14 2014-03-07 CDC7 Inhibitors

Publications (1)

Publication Number Publication Date
AP2015008734A0 true AP2015008734A0 (en) 2015-09-30

Family

ID=50382704

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008734A AP2015008734A0 (en) 2013-03-14 2014-03-07 Cdc7 inhibitors

Country Status (37)

Country Link
US (1) US9156824B2 (sr)
EP (1) EP2970221B1 (sr)
JP (1) JP6064079B2 (sr)
KR (1) KR101718645B1 (sr)
CN (1) CN105008351B (sr)
AP (1) AP2015008734A0 (sr)
AU (1) AU2014228374B2 (sr)
BR (1) BR112015020466B1 (sr)
CA (1) CA2900773C (sr)
CL (1) CL2015002530A1 (sr)
CR (1) CR20150416A (sr)
CY (1) CY1119199T1 (sr)
DK (1) DK2970221T3 (sr)
EA (1) EA027012B1 (sr)
ES (1) ES2639793T3 (sr)
GT (1) GT201500263A (sr)
HK (1) HK1212696A1 (sr)
HR (1) HRP20171151T1 (sr)
HU (1) HUE033482T2 (sr)
IL (1) IL240962B (sr)
JO (1) JO3383B1 (sr)
LT (1) LT2970221T (sr)
ME (1) ME02805B (sr)
MX (1) MX363438B (sr)
MY (1) MY188145A (sr)
NZ (1) NZ710392A (sr)
PE (1) PE20151654A1 (sr)
PH (1) PH12015502091A1 (sr)
PL (1) PL2970221T3 (sr)
PT (1) PT2970221T (sr)
RS (1) RS56122B1 (sr)
SG (1) SG11201507541PA (sr)
SI (1) SI2970221T1 (sr)
TN (1) TN2015000349A1 (sr)
TW (1) TWI622396B (sr)
UA (1) UA116125C2 (sr)
WO (1) WO2014143601A1 (sr)

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ES2615743T3 (es) * 2012-10-15 2017-06-08 Pfizer Ireland Pharmaceuticals Procedimiento de preparación de voriconazol y análogos de los mismos
WO2014110574A1 (en) 2013-01-14 2014-07-17 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
SG10201705662WA (en) 2013-01-15 2017-08-30 Incyte Corp Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors
TWI627174B (zh) 2013-03-14 2018-06-21 比利時商健生藥品公司 P2x7調控劑
NZ710034A (en) 2013-03-14 2020-06-26 Boehringer Ingelheim Int Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c
WO2014152537A1 (en) 2013-03-14 2014-09-25 Janssen Pharmaceutica Nv P2x7 modulators
JO3773B1 (ar) 2013-03-14 2021-01-31 Janssen Pharmaceutica Nv معدلات p2x7
EP2970271B1 (en) 2013-03-14 2017-11-08 Janssen Pharmaceutica NV P2x7 modulators
PE20160532A1 (es) 2013-08-23 2016-05-21 Incyte Corp Compuesto de carboxamida de furo y tienopiridina utiles como inhibidores de cinasas pim
US9580418B2 (en) 2014-07-14 2017-02-28 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
WO2016010897A1 (en) 2014-07-14 2016-01-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
ES2714048T3 (es) 2014-09-12 2019-05-24 Janssen Pharmaceutica Nv Moduladores de P2X7
KR102510588B1 (ko) 2014-09-12 2023-03-17 베링거 인겔하임 인터내셔날 게엠베하 카텝신 c의 스피로사이클릭 억제제
WO2016196244A1 (en) 2015-05-29 2016-12-08 Incyte Corporation Pyridineamine compounds useful as pim kinase inhibitors
TWI734699B (zh) 2015-09-09 2021-08-01 美商英塞特公司 Pim激酶抑制劑之鹽
TW201718546A (zh) 2015-10-02 2017-06-01 英塞特公司 適用作pim激酶抑制劑之雜環化合物
EP3515903B1 (en) * 2016-09-22 2020-10-21 Cancer Research Technology Limited Preparation and uses of pyrimidinone derivatives
US10596161B2 (en) 2017-12-08 2020-03-24 Incyte Corporation Low dose combination therapy for treatment of myeloproliferative neoplasms
CN108383771A (zh) * 2018-01-08 2018-08-10 华东师范大学 手性3,3-二取代异吲哚啉-1-酮衍生物及其合成方法和应用
GB201807147D0 (en) 2018-05-01 2018-06-13 Oncologica Uk Ltd Therapeutic combination
NL2021185B1 (en) 2018-06-26 2020-01-06 Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis Combination Therapy and Use Thereof for Treating Cancer
EP3856178A1 (en) 2018-09-28 2021-08-04 Janssen Pharmaceutica NV Monoacylglycerol lipase modulators
EP3856179A1 (en) 2018-09-28 2021-08-04 Janssen Pharmaceutica N.V. Monoacylglycerol lipase modulators
US20220220125A1 (en) * 2019-04-16 2022-07-14 Janssen Pharmaceutica Nv Fused isoindolin-1-one derivatives useful as grk2 inhibitors
US11839663B2 (en) 2019-09-30 2023-12-12 Janssen Pharmaceutica Nv Radiolabelled MGL pet ligands
JP2023518511A (ja) 2020-03-26 2023-05-01 ヤンセン ファーマシューティカ エヌ.ベー. モノアシルグリセロールリパーゼ調節因子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0400970D0 (sv) * 2004-04-14 2004-04-14 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
TW200639163A (en) * 2005-02-04 2006-11-16 Genentech Inc RAF inhibitor compounds and methods
US7576082B2 (en) * 2005-06-24 2009-08-18 Hoffman-La Roche Inc. Oxindole derivatives
WO2008060789A2 (en) * 2006-10-12 2008-05-22 Xenon Pharmaceuticals Inc. Use of spiro-oxindole compounds as therapeutic agents
BRPI0811065A2 (pt) * 2007-06-08 2014-12-02 Abbott Lab Indazóis 5-heteroaril substituídos como inibidores de quinase
US8648069B2 (en) * 2007-06-08 2014-02-11 Abbvie Inc. 5-substituted indazoles as kinase inhibitors

Also Published As

Publication number Publication date
ME02805B (me) 2018-01-20
SI2970221T1 (sl) 2017-08-31
PE20151654A1 (es) 2015-11-12
US9156824B2 (en) 2015-10-13
RS56122B1 (sr) 2017-10-31
AU2014228374B2 (en) 2016-09-01
US20140275121A1 (en) 2014-09-18
AU2014228374A1 (en) 2015-08-06
JP6064079B2 (ja) 2017-01-18
TN2015000349A1 (en) 2017-01-03
ES2639793T3 (es) 2017-10-30
MY188145A (en) 2021-11-23
CN105008351A (zh) 2015-10-28
CL2015002530A1 (es) 2016-03-28
JP2016512498A (ja) 2016-04-28
TW201521726A (zh) 2015-06-16
BR112015020466B1 (pt) 2022-07-26
PL2970221T3 (pl) 2017-11-30
PH12015502091B1 (en) 2016-01-18
WO2014143601A1 (en) 2014-09-18
EP2970221B1 (en) 2017-06-28
CY1119199T1 (el) 2018-02-14
IL240962A0 (en) 2015-11-30
UA116125C2 (uk) 2018-02-12
PT2970221T (pt) 2017-09-22
LT2970221T (lt) 2017-09-11
MX363438B (es) 2019-03-22
NZ710392A (en) 2020-05-29
KR101718645B1 (ko) 2017-03-21
EA201591509A1 (ru) 2015-12-30
DK2970221T3 (en) 2017-07-31
CR20150416A (es) 2015-09-16
BR112015020466A8 (pt) 2019-11-12
EP2970221A1 (en) 2016-01-20
EA027012B1 (ru) 2017-06-30
CN105008351B (zh) 2017-03-15
SG11201507541PA (en) 2015-10-29
HRP20171151T1 (hr) 2017-10-06
CA2900773A1 (en) 2014-09-18
CA2900773C (en) 2018-04-17
TWI622396B (zh) 2018-05-01
GT201500263A (es) 2016-03-02
JO3383B1 (ar) 2019-03-13
MX2015012583A (es) 2016-01-20
HK1212696A1 (zh) 2016-06-17
IL240962B (en) 2020-04-30
BR112015020466A2 (pt) 2017-07-18
HUE033482T2 (en) 2017-12-28
KR20150119101A (ko) 2015-10-23
PH12015502091A1 (en) 2016-01-18

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