AP2015008734A0 - Cdc7 inhibitors - Google Patents

Cdc7 inhibitors

Info

Publication number
AP2015008734A0
AP2015008734A0 AP2015008734A AP2015008734A AP2015008734A0 AP 2015008734 A0 AP2015008734 A0 AP 2015008734A0 AP 2015008734 A AP2015008734 A AP 2015008734A AP 2015008734 A AP2015008734 A AP 2015008734A AP 2015008734 A0 AP2015008734 A0 AP 2015008734A0
Authority
AP
ARIPO
Prior art keywords
cdc7 inhibitors
cdc7
inhibitors
Prior art date
Application number
AP2015008734A
Other languages
English (en)
Inventor
Timothy Andrew Woods
Robert Dean Dally
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AP2015008734A0 publication Critical patent/AP2015008734A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
AP2015008734A 2013-03-14 2014-03-07 Cdc7 inhibitors AP2015008734A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361782798P 2013-03-14 2013-03-14
US201361789108P 2013-03-15 2013-03-15
PCT/US2014/021466 WO2014143601A1 (en) 2013-03-14 2014-03-07 CDC7 Inhibitors

Publications (1)

Publication Number Publication Date
AP2015008734A0 true AP2015008734A0 (en) 2015-09-30

Family

ID=50382704

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008734A AP2015008734A0 (en) 2013-03-14 2014-03-07 Cdc7 inhibitors

Country Status (37)

Country Link
US (1) US9156824B2 (lt)
EP (1) EP2970221B1 (lt)
JP (1) JP6064079B2 (lt)
KR (1) KR101718645B1 (lt)
CN (1) CN105008351B (lt)
AP (1) AP2015008734A0 (lt)
AU (1) AU2014228374B2 (lt)
BR (1) BR112015020466B1 (lt)
CA (1) CA2900773C (lt)
CL (1) CL2015002530A1 (lt)
CR (1) CR20150416A (lt)
CY (1) CY1119199T1 (lt)
DK (1) DK2970221T3 (lt)
EA (1) EA027012B1 (lt)
ES (1) ES2639793T3 (lt)
GT (1) GT201500263A (lt)
HK (1) HK1212696A1 (lt)
HR (1) HRP20171151T1 (lt)
HU (1) HUE033482T2 (lt)
IL (1) IL240962B (lt)
JO (1) JO3383B1 (lt)
LT (1) LT2970221T (lt)
ME (1) ME02805B (lt)
MX (1) MX363438B (lt)
MY (1) MY188145A (lt)
NZ (1) NZ710392A (lt)
PE (1) PE20151654A1 (lt)
PH (1) PH12015502091A1 (lt)
PL (1) PL2970221T3 (lt)
PT (1) PT2970221T (lt)
RS (1) RS56122B1 (lt)
SG (1) SG11201507541PA (lt)
SI (1) SI2970221T1 (lt)
TN (1) TN2015000349A1 (lt)
TW (1) TWI622396B (lt)
UA (1) UA116125C2 (lt)
WO (1) WO2014143601A1 (lt)

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NZ706764A (en) * 2012-10-15 2017-11-24 Pfizer Ireland Pharmaceuticals Process for the preparation of voriconazole and analogues thereof
JP6437452B2 (ja) 2013-01-14 2018-12-12 インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation Pimキナーゼ阻害剤として有用な二環式芳香族カルボキサミド化合物
KR102403306B1 (ko) 2013-01-15 2022-06-02 인사이트 홀딩스 코포레이션 Pim 키나제 저해제로서 유용한 티아졸카복스아마이드 및 피리딘카복스아마이드 화합물
TWI599567B (zh) 2013-03-14 2017-09-21 健生藥品公司 P2x7調節劑
WO2014152589A1 (en) 2013-03-14 2014-09-25 Janssen Pharmaceutica Nv P2x7 modulators
JP6467404B2 (ja) 2013-03-14 2019-02-13 ヤンセン ファーマシューティカ エヌ.ベー. P2x7モジュレーター
EA029052B1 (ru) 2013-03-14 2018-02-28 Бёрингер Ингельхайм Интернациональ Гмбх Замещенные (бензилцианометил)амиды 2-азабицикло[2.2.1]гептан-3-карбоновых кислот в качестве ингибиторов катепсина с
TWI627174B (zh) 2013-03-14 2018-06-21 比利時商健生藥品公司 P2x7調控劑
JP2016528298A (ja) 2013-08-23 2016-09-15 インサイト・コーポレイションIncyte Corporation Pimキナーゼ阻害剤として有用なフロピリジン及びチエノピリジンカルボキシアミド化合物
WO2016010897A1 (en) 2014-07-14 2016-01-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
US9580418B2 (en) 2014-07-14 2017-02-28 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
AP2017009733A0 (en) 2014-09-12 2017-02-28 Boehringer Ingelheim Int Spirocyclic inhibitors of cathepsin c
US10150766B2 (en) 2014-09-12 2018-12-11 Janssen Pharmaceutica Nv P2X7 modulators
WO2016196244A1 (en) 2015-05-29 2016-12-08 Incyte Corporation Pyridineamine compounds useful as pim kinase inhibitors
TWI734699B (zh) 2015-09-09 2021-08-01 美商英塞特公司 Pim激酶抑制劑之鹽
WO2017059251A1 (en) 2015-10-02 2017-04-06 Incyte Corporation Heterocyclic compounds useful as pim kinase inhibitors
JP7118974B2 (ja) * 2016-09-22 2022-08-16 キャンサー・リサーチ・テクノロジー・リミテッド ピリミジノン誘導体の調製および使用
AR113922A1 (es) 2017-12-08 2020-07-01 Incyte Corp Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
CN108383771A (zh) * 2018-01-08 2018-08-10 华东师范大学 手性3,3-二取代异吲哚啉-1-酮衍生物及其合成方法和应用
GB201807147D0 (en) 2018-05-01 2018-06-13 Oncologica Uk Ltd Therapeutic combination
NL2021185B1 (en) 2018-06-26 2020-01-06 Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis Combination Therapy and Use Thereof for Treating Cancer
EA202190886A1 (ru) 2018-09-28 2021-09-07 Янссен Фармацевтика Нв Модуляторы моноацилглицерин-липазы
TW202035409A (zh) 2018-09-28 2020-10-01 比利時商健生藥品公司 單醯基甘油脂肪酶調節劑
US20220220125A1 (en) * 2019-04-16 2022-07-14 Janssen Pharmaceutica Nv Fused isoindolin-1-one derivatives useful as grk2 inhibitors
CN114555596A (zh) 2019-09-30 2022-05-27 詹森药业有限公司 放射性标记的mgl pet配体
BR112022019077A2 (pt) 2020-03-26 2022-12-27 Janssen Pharmaceutica Nv Moduladores da monoacilglicerol lipase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0400970D0 (sv) * 2004-04-14 2004-04-14 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
TW200639163A (en) * 2005-02-04 2006-11-16 Genentech Inc RAF inhibitor compounds and methods
US7576082B2 (en) * 2005-06-24 2009-08-18 Hoffman-La Roche Inc. Oxindole derivatives
MX2009003876A (es) * 2006-10-12 2009-05-11 Xenon Pharmaceuticals Inc Uso de compuestos de espiro-oxindol como agentes terapeuticos.
AU2008262038A1 (en) * 2007-06-08 2008-12-18 AbbVie Deutschland GmbH & Co. KG 5-heteroaryl substituted indazoles as kinase inhibitors
US8648069B2 (en) * 2007-06-08 2014-02-11 Abbvie Inc. 5-substituted indazoles as kinase inhibitors

Also Published As

Publication number Publication date
PL2970221T3 (pl) 2017-11-30
TWI622396B (zh) 2018-05-01
KR101718645B1 (ko) 2017-03-21
IL240962A0 (en) 2015-11-30
CY1119199T1 (el) 2018-02-14
CN105008351B (zh) 2017-03-15
PH12015502091B1 (en) 2016-01-18
AU2014228374B2 (en) 2016-09-01
MX363438B (es) 2019-03-22
TN2015000349A1 (en) 2017-01-03
AU2014228374A1 (en) 2015-08-06
US9156824B2 (en) 2015-10-13
PT2970221T (pt) 2017-09-22
DK2970221T3 (en) 2017-07-31
MX2015012583A (es) 2016-01-20
CR20150416A (es) 2015-09-16
KR20150119101A (ko) 2015-10-23
US20140275121A1 (en) 2014-09-18
CA2900773A1 (en) 2014-09-18
RS56122B1 (sr) 2017-10-31
EA027012B1 (ru) 2017-06-30
NZ710392A (en) 2020-05-29
ME02805B (me) 2018-01-20
PH12015502091A1 (en) 2016-01-18
BR112015020466A8 (pt) 2019-11-12
EP2970221B1 (en) 2017-06-28
JP2016512498A (ja) 2016-04-28
HUE033482T2 (en) 2017-12-28
CN105008351A (zh) 2015-10-28
LT2970221T (lt) 2017-09-11
SG11201507541PA (en) 2015-10-29
CA2900773C (en) 2018-04-17
BR112015020466B1 (pt) 2022-07-26
HK1212696A1 (zh) 2016-06-17
GT201500263A (es) 2016-03-02
HRP20171151T1 (hr) 2017-10-06
JP6064079B2 (ja) 2017-01-18
TW201521726A (zh) 2015-06-16
BR112015020466A2 (pt) 2017-07-18
PE20151654A1 (es) 2015-11-12
IL240962B (en) 2020-04-30
UA116125C2 (uk) 2018-02-12
CL2015002530A1 (es) 2016-03-28
EA201591509A1 (ru) 2015-12-30
SI2970221T1 (sl) 2017-08-31
JO3383B1 (ar) 2019-03-13
EP2970221A1 (en) 2016-01-20
ES2639793T3 (es) 2017-10-30
MY188145A (en) 2021-11-23
WO2014143601A1 (en) 2014-09-18

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