AP2011005695A0 - Therapeutic antiviral poptides. - Google Patents
Therapeutic antiviral poptides.Info
- Publication number
- AP2011005695A0 AP2011005695A0 AP2011005695A AP2011005695A AP2011005695A0 AP 2011005695 A0 AP2011005695 A0 AP 2011005695A0 AP 2011005695 A AP2011005695 A AP 2011005695A AP 2011005695 A AP2011005695 A AP 2011005695A AP 2011005695 A0 AP2011005695 A0 AP 2011005695A0
- Authority
- AP
- ARIPO
- Prior art keywords
- poptides
- therapeutic antiviral
- antiviral
- therapeutic
- antiviral poptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10574608P | 2008-10-15 | 2008-10-15 | |
US23674109P | 2009-08-25 | 2009-08-25 | |
PCT/US2009/060558 WO2010045266A1 (en) | 2008-10-15 | 2009-10-13 | Therapeutic antiviral peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
AP2011005695A0 true AP2011005695A0 (en) | 2011-06-30 |
Family
ID=41346045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2011005695A AP2011005695A0 (en) | 2008-10-15 | 2009-10-13 | Therapeutic antiviral poptides. |
Country Status (21)
Country | Link |
---|---|
US (1) | US20100119479A1 (es) |
EP (1) | EP2358736A1 (es) |
JP (1) | JP2012505897A (es) |
KR (1) | KR20110075019A (es) |
CN (1) | CN102216321A (es) |
AP (1) | AP2011005695A0 (es) |
AR (1) | AR073880A1 (es) |
AU (1) | AU2009303483A1 (es) |
CA (1) | CA2740728A1 (es) |
CL (1) | CL2011000846A1 (es) |
CO (1) | CO6362017A2 (es) |
EA (1) | EA201170441A1 (es) |
EC (1) | ECSP11011054A (es) |
IL (1) | IL212097A0 (es) |
MA (1) | MA32787B1 (es) |
MX (1) | MX2011004007A (es) |
NI (1) | NI201100076A (es) |
TN (1) | TN2011000172A1 (es) |
TW (1) | TW201019950A (es) |
WO (1) | WO2010045266A1 (es) |
ZA (1) | ZA201102822B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7491794B2 (en) * | 2003-10-14 | 2009-02-17 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
WO2007015824A2 (en) * | 2005-07-25 | 2007-02-08 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
WO2007044893A2 (en) * | 2005-10-11 | 2007-04-19 | Intermune, Inc. | Compounds and methods for inhibiting hepatitis c viral replication |
RU2008152171A (ru) * | 2006-07-05 | 2010-08-10 | Интермьюн, Инк. (Us) | Новые ингибиторы вирусной репликации гепатита с |
BRPI0811020A2 (pt) * | 2007-05-03 | 2015-07-21 | Intermune Inc | Composto, composição farmacêutica e métodos de inibição da atividade da protease ns3/ns4, de tratamento da fibrose hepática, de intensificação da função hepática em indivíduo com infecção do vírus da hepatite c e métodos de síntese de compostos, de administração de inibidor da infecção do vírus da hepatite c (hcv) e de distribuição de forma de dosagem oral. |
CA2686546A1 (en) * | 2007-05-10 | 2008-11-20 | Intermune, Inc. | Novel peptide inhibitors of hepatitis c virus replication |
MX2010011306A (es) * | 2008-04-15 | 2010-11-09 | Intermune Inc | Nuevos inhibidores macrociclicos de la replicacion del virus de la hepatitis c. |
AR075584A1 (es) * | 2009-02-27 | 2011-04-20 | Intermune Inc | COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO. |
US20110081315A1 (en) * | 2009-09-28 | 2011-04-07 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
WO2012047764A1 (en) * | 2010-10-04 | 2012-04-12 | Intermune, Inc. | Therapeutic antiviral peptides |
EP2583680A3 (en) | 2011-10-21 | 2013-06-12 | Abbvie Inc. | Mono (PSI-7977) or combination treatment of DAAs for use in treating HCV |
SE1450130A1 (sv) | 2011-10-21 | 2014-05-07 | Abbvie Inc | Förfaranden för att behandla hcv innefattande minst två direktverkande antivirala agenser, ribavirin men inte interferon |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
WO2013074386A2 (en) | 2011-11-15 | 2013-05-23 | Merck Sharp & Dohme Corp. | Hcv ns3 protease inhibitors |
UA119315C2 (uk) | 2012-07-03 | 2019-06-10 | Гіліад Фармассет Елелсі | Інгібітори вірусу гепатиту с |
EA029088B1 (ru) | 2013-03-15 | 2018-02-28 | Джилид Сайэнс, Инк. | Макроциклические и бициклические ингибиторы вируса гепатита c |
CN104803918B (zh) * | 2014-01-26 | 2017-11-10 | 上海医药工业研究院 | 恩杂鲁胺的制备方法 |
CN105175491B (zh) * | 2015-07-13 | 2019-01-11 | 山东大学 | 一种含有羟脯氨酸骨架的多肽类ns3丝氨酸蛋白酶抑制剂及其制备方法和应用 |
CA3022119A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3547119A (en) | 1967-12-08 | 1970-12-15 | Baxter Laboratories Inc | Catheter assembly |
US4211771A (en) | 1971-06-01 | 1980-07-08 | Robins Ronald K | Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide |
US3798209A (en) * | 1971-06-01 | 1974-03-19 | Icn Pharmaceuticals | 1,2,4-triazole nucleosides |
US4311137A (en) | 1980-04-30 | 1982-01-19 | Sherwood Medical Industries Inc. | Infusion device |
US4531937A (en) | 1983-01-24 | 1985-07-30 | Pacesetter Systems, Inc. | Introducer catheter apparatus and method of use |
CS263951B1 (en) * | 1985-04-25 | 1989-05-12 | Antonin Holy | 9-(phosponylmethoxyalkyl)adenines and method of their preparation |
US4755173A (en) | 1986-02-25 | 1988-07-05 | Pacesetter Infusion, Ltd. | Soft cannula subcutaneous injection set |
CS264222B1 (en) * | 1986-07-18 | 1989-06-13 | Holy Antonin | N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them |
US5130421A (en) * | 1988-03-24 | 1992-07-14 | Bristol-Myers Company | Production of 2',3'-dideoxy-2',3'-didehydronucleosides |
US5354866A (en) | 1989-05-23 | 1994-10-11 | Abbott Laboratories | Retroviral protease inhibiting compounds |
US5552558A (en) | 1989-05-23 | 1996-09-03 | Abbott Laboratories | Retroviral protease inhibiting compounds |
GB8918806D0 (en) * | 1989-08-17 | 1989-09-27 | Shell Int Research | Chiral compounds,their preparation and use |
US5716632A (en) | 1989-11-22 | 1998-02-10 | Margolin; Solomon B. | Compositions and methods for reparation and prevention of fibrotic lesions |
US5310562A (en) | 1989-11-22 | 1994-05-10 | Margolin Solomon B | Composition and method for reparation and prevention of fibrotic lesions |
US5518729A (en) | 1989-11-22 | 1996-05-21 | Margolin; Solomon B. | Compositions and methods for reparation and prevention of fibrotic lesions |
ES2118069T3 (es) * | 1990-09-14 | 1998-09-16 | Acad Of Science Czech Republic | Profarmacos de fosfonatos. |
PT727419E (pt) | 1992-12-29 | 2002-08-30 | Abbott Lab | Compostos intermediarios para a preparacao de inibidores da protease retroviral |
US5545143A (en) | 1993-01-21 | 1996-08-13 | T. S. I. Medical | Device for subcutaneous medication delivery |
US6090822A (en) | 1995-03-03 | 2000-07-18 | Margolin; Solomon B. | Treatment of cytokine growth factor caused disorders |
US6232333B1 (en) | 1996-11-21 | 2001-05-15 | Abbott Laboratories | Pharmaceutical composition |
US6323180B1 (en) * | 1998-08-10 | 2001-11-27 | Boehringer Ingelheim (Canada) Ltd | Hepatitis C inhibitor tri-peptides |
US6277830B1 (en) | 1998-10-16 | 2001-08-21 | Schering Corporation | 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon |
US7256005B2 (en) | 1999-08-10 | 2007-08-14 | The Chancellor, Masters And Scholars Of The University Of Oxford | Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity |
RU2355700C9 (ru) * | 2000-07-21 | 2010-03-20 | Шеринг Корпорейшн | Новые пептиды как ингибиторы ns3-серинпротеазы вируса гепатита с |
WO2002060926A2 (en) * | 2000-11-20 | 2002-08-08 | Bristol-Myers Squibb Company | Hepatitis c tripeptide inhibitors |
US7352694B1 (en) * | 2001-12-14 | 2008-04-01 | Applied Micro Circuits Corporation | System and method for tolerating data link faults in a packet communications switch fabric |
TW200403236A (en) * | 2002-04-11 | 2004-03-01 | Vertex Pharma | Inhibitors or serine proteases, particularly HCV NS3-NS4A protease |
CA2481285A1 (en) * | 2002-04-26 | 2003-11-06 | Gilead Sciences, Inc. | Non nucleoside reverse transcriptase inhibitors |
AU2003301959A1 (en) * | 2002-05-20 | 2004-06-03 | Bristol-Myers Squibb Company | Substituted cycloalkyl p1' hepatitis c virus inhibitors |
EP1613620A1 (en) * | 2003-04-11 | 2006-01-11 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
US7300924B2 (en) * | 2003-04-25 | 2007-11-27 | Gilead Sciences, Inc. | Anti-infective phosphonate analogs |
ATE497505T1 (de) * | 2003-09-26 | 2011-02-15 | Schering Corp | Makrocyclische inhibitoren der ns3-serinprotease des hepatitis-c-virus |
WO2005037860A2 (en) * | 2003-10-10 | 2005-04-28 | Vertex Pharmaceuticals Incoporated | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
US7816326B2 (en) * | 2004-02-27 | 2010-10-19 | Schering Corporation | Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease |
EP1763531A4 (en) * | 2004-06-28 | 2009-07-01 | Boehringer Ingelheim Int | ANALOGUE OF HEPATITIS-C INHIBITING PEPTIDES |
WO2007015824A2 (en) * | 2005-07-25 | 2007-02-08 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
AU2006275413B2 (en) * | 2005-08-02 | 2012-07-19 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
WO2007044893A2 (en) * | 2005-10-11 | 2007-04-19 | Intermune, Inc. | Compounds and methods for inhibiting hepatitis c viral replication |
US7705138B2 (en) * | 2005-11-11 | 2010-04-27 | Vertex Pharmaceuticals Incorporated | Hepatitis C virus variants |
BRPI0709567A2 (pt) * | 2006-03-16 | 2011-07-12 | Vertex Pharma | inibidores deuterados de protease de hepatite c |
US7582605B2 (en) * | 2006-08-11 | 2009-09-01 | Enanta Pharmaceuticals, Inc. | Phosphorus-containing hepatitis C serine protease inhibitors |
US7772180B2 (en) * | 2006-11-09 | 2010-08-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7763584B2 (en) * | 2006-11-16 | 2010-07-27 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2008098368A1 (en) * | 2007-02-16 | 2008-08-21 | Boehringer Ingelheim International Gmbh | Inhibitors of hepatitis c ns3 protease |
US8093257B2 (en) * | 2007-05-04 | 2012-01-10 | Bristol-Myers Squibb Company | [6,5]-bicyclic GPR119 G protein-coupled receptor agonists |
CA2686546A1 (en) * | 2007-05-10 | 2008-11-20 | Intermune, Inc. | Novel peptide inhibitors of hepatitis c virus replication |
US8255080B2 (en) * | 2007-09-04 | 2012-08-28 | Hermes Promethean Ventures Inc. | Digital content distribution system |
CN104016970A (zh) * | 2007-10-10 | 2014-09-03 | 诺华股份有限公司 | 螺环吡咯烷类与其对抗hcv和hiv感染的应用 |
MX2010011306A (es) * | 2008-04-15 | 2010-11-09 | Intermune Inc | Nuevos inhibidores macrociclicos de la replicacion del virus de la hepatitis c. |
US8765667B2 (en) * | 2008-08-20 | 2014-07-01 | Michael Eissenstat | HCV protease inhibitors |
US8603737B2 (en) * | 2008-09-19 | 2013-12-10 | Celgene Avilomics Research, Inc. | Methods for identifying HCV protease inhibitors |
EP2344487A4 (en) * | 2008-09-23 | 2012-03-21 | Boehringer Ingelheim Int | HEPATITIS C INHIBITOR COMPOUNDS |
JP2012503669A (ja) * | 2008-09-24 | 2012-02-09 | バーテックス ファーマシューティカルズ インコーポレイテッド | 肝炎を治療するためのpeg−インターフェロン、リバビリンおよびvx−950を含む治療レジメ |
US20100080770A1 (en) * | 2008-09-29 | 2010-04-01 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
US8044087B2 (en) * | 2008-09-29 | 2011-10-25 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8563505B2 (en) * | 2008-09-29 | 2013-10-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
EP2350114A1 (en) * | 2008-11-20 | 2011-08-03 | Achillion Pharmaceuticals, Inc. | Cyclic carboxamide compounds and analogues thereof as of hepatitis c virus |
BRPI0922913A2 (pt) * | 2008-12-10 | 2015-08-18 | Achillion Pharmaceuticals Inc | Análogos cíclicos de peptídeo 4-amino-4-oxobutanoil inibidores de replicação viral |
US8283310B2 (en) * | 2008-12-15 | 2012-10-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
JP2012512878A (ja) * | 2008-12-19 | 2012-06-07 | ギリアード サイエンシーズ, インコーポレイテッド | Hcvns3プロテアーゼインヒビター |
UY32332A (es) * | 2008-12-22 | 2010-07-30 | Gilead Sciences Inc | Compuestos macrocíclicos sus prodrogas, n-óxidos, sales de adición, aminas cuaternarias, complejos de metales y formas estereoquímicamente isoméricas puras. |
US20100196321A1 (en) * | 2009-01-30 | 2010-08-05 | Glaxosmithkline Llc | Compounds |
CA2758072A1 (en) * | 2009-04-08 | 2010-10-14 | Idenix Pharmaceuticals, Inc. | Macrocyclic serine protease inhibitors |
US8512690B2 (en) * | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
MX2011011105A (es) * | 2009-04-25 | 2011-11-18 | Hoffmann La Roche | Procedimientos para mejorar la farmocinetica. |
US20100324059A1 (en) * | 2009-06-23 | 2010-12-23 | Gilead Sciences, Inc. | Pharmaceutical compositions useful for treating hcv |
AR077125A1 (es) * | 2009-06-23 | 2011-08-03 | Gilead Sciences Inc | Combinaciones farmaceuticas utiles para tratar el vhc |
US20100324060A1 (en) * | 2009-06-23 | 2010-12-23 | Gilead Sciences, Inc. | Pharmaceutical compositions useful for treating hcv |
US8232246B2 (en) * | 2009-06-30 | 2012-07-31 | Abbott Laboratories | Anti-viral compounds |
US20110064694A1 (en) * | 2009-09-09 | 2011-03-17 | Yale University | Anti-hepatitis c activity of meso-tetrakis-porphyrin analogues |
US8759332B2 (en) * | 2009-09-11 | 2014-06-24 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
US8927709B2 (en) * | 2009-09-11 | 2015-01-06 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
US8703938B2 (en) * | 2009-09-11 | 2014-04-22 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
US8822700B2 (en) * | 2009-09-11 | 2014-09-02 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
WO2011031904A1 (en) * | 2009-09-11 | 2011-03-17 | Enanta Pharmaceuticals, Inc | Hepatitis c virus inhibitors |
US8815928B2 (en) * | 2009-09-11 | 2014-08-26 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
HUE030402T2 (en) * | 2009-09-15 | 2017-05-29 | Taigen Biotechnology Co Ltd | HCV protease inhibitors |
US20110081315A1 (en) * | 2009-09-28 | 2011-04-07 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
BR112012006835A2 (pt) * | 2009-09-28 | 2016-06-07 | Hoffmann La Roche | inibidores macrocíclicos da replicação do vírus de hepatite c |
WO2011041551A1 (en) * | 2009-10-01 | 2011-04-07 | Intermune, Inc. | Therapeutic antiviral peptides |
WO2011047119A1 (en) * | 2009-10-14 | 2011-04-21 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis c |
JP5664471B2 (ja) * | 2010-06-28 | 2015-02-04 | 信越化学工業株式会社 | 半導体用合成石英ガラス基板の製造方法 |
-
2009
- 2009-10-13 JP JP2011532192A patent/JP2012505897A/ja active Pending
- 2009-10-13 KR KR1020117011023A patent/KR20110075019A/ko not_active Application Discontinuation
- 2009-10-13 CA CA2740728A patent/CA2740728A1/en not_active Abandoned
- 2009-10-13 AP AP2011005695A patent/AP2011005695A0/xx unknown
- 2009-10-13 EP EP09740803A patent/EP2358736A1/en not_active Withdrawn
- 2009-10-13 MX MX2011004007A patent/MX2011004007A/es not_active Application Discontinuation
- 2009-10-13 AU AU2009303483A patent/AU2009303483A1/en not_active Abandoned
- 2009-10-13 CN CN2009801452268A patent/CN102216321A/zh active Pending
- 2009-10-13 WO PCT/US2009/060558 patent/WO2010045266A1/en active Application Filing
- 2009-10-13 EA EA201170441A patent/EA201170441A1/ru unknown
- 2009-10-14 US US12/579,275 patent/US20100119479A1/en not_active Abandoned
- 2009-10-15 TW TW098134982A patent/TW201019950A/zh unknown
- 2009-10-15 AR ARP090103978A patent/AR073880A1/es unknown
-
2011
- 2011-04-03 IL IL212097A patent/IL212097A0/en unknown
- 2011-04-12 TN TN2011000172A patent/TN2011000172A1/fr unknown
- 2011-04-14 ZA ZA2011/02822A patent/ZA201102822B/en unknown
- 2011-04-15 CL CL2011000846A patent/CL2011000846A1/es unknown
- 2011-04-15 NI NI201100076A patent/NI201100076A/es unknown
- 2011-04-25 CO CO11050437A patent/CO6362017A2/es not_active Application Discontinuation
- 2011-05-11 MA MA33835A patent/MA32787B1/fr unknown
- 2011-05-13 EC EC2011011054A patent/ECSP11011054A/es unknown
Also Published As
Publication number | Publication date |
---|---|
CO6362017A2 (es) | 2012-01-20 |
CL2011000846A1 (es) | 2011-09-30 |
JP2012505897A (ja) | 2012-03-08 |
TN2011000172A1 (en) | 2012-12-17 |
KR20110075019A (ko) | 2011-07-05 |
TW201019950A (en) | 2010-06-01 |
ZA201102822B (en) | 2011-12-28 |
EP2358736A1 (en) | 2011-08-24 |
EA201170441A1 (ru) | 2012-05-30 |
MA32787B1 (fr) | 2011-11-01 |
CA2740728A1 (en) | 2010-04-22 |
AU2009303483A1 (en) | 2010-04-22 |
CN102216321A (zh) | 2011-10-12 |
US20100119479A1 (en) | 2010-05-13 |
AR073880A1 (es) | 2010-12-09 |
MX2011004007A (es) | 2011-05-19 |
ECSP11011054A (es) | 2011-10-31 |
WO2010045266A1 (en) | 2010-04-22 |
IL212097A0 (en) | 2011-06-30 |
NI201100076A (es) | 2012-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP2011005695A0 (en) | Therapeutic antiviral poptides. | |
IL207826A0 (en) | Antiviral therapeutic agents | |
AP2011005987A0 (en) | Antiviral compounds. | |
GB0815968D0 (en) | Antiviral agents | |
IL206654A0 (en) | Combination therapy | |
GB0709791D0 (en) | Antiviral agents | |
IL208351A0 (en) | Antiviral therapy | |
IL199992A0 (en) | Combination therapy | |
GB0710995D0 (en) | Combines | |
GB0707000D0 (en) | Antiviral agents | |
GB0710994D0 (en) | Combines | |
GB0719518D0 (en) | Therapy | |
GB0805264D0 (en) | Antiviral agents | |
GB0711032D0 (en) | Combines | |
GB0803707D0 (en) | Antiviral agent | |
GB0803054D0 (en) | Medicament | |
EP2211863A4 (en) | COMBINATION THERAPY | |
GB0905485D0 (en) | Antiviral therapy | |
GB0700284D0 (en) | Combination therapy | |
GB0723609D0 (en) | Antiviral | |
GB0803948D0 (en) | Combination therapy | |
GB0717450D0 (en) | Medicament | |
GB0711031D0 (en) | Combines | |
GB0707429D0 (en) | HIV Therapy | |
GB0716072D0 (en) | Therapy |