AP1374A - Aerosolizable particles resistant to hygroscopic growth. - Google Patents
Aerosolizable particles resistant to hygroscopic growth. Download PDFInfo
- Publication number
- AP1374A AP1374A APAP/P/2001/002093A AP2001002093A AP1374A AP 1374 A AP1374 A AP 1374A AP 2001002093 A AP2001002093 A AP 2001002093A AP 1374 A AP1374 A AP 1374A
- Authority
- AP
- ARIPO
- Prior art keywords
- particles
- active agent
- hygroscopic
- growth inhibitor
- hygroscopic growth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10016398P | 1998-09-14 | 1998-09-14 | |
PCT/US1999/021109 WO2000015262A1 (en) | 1998-09-14 | 1999-09-13 | Dry powder active agent pulmonary delivery |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2001002093A0 AP2001002093A0 (en) | 2001-03-31 |
AP1374A true AP1374A (en) | 2005-02-28 |
Family
ID=22278404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/2001/002093A AP1374A (en) | 1998-09-14 | 1999-09-13 | Aerosolizable particles resistant to hygroscopic growth. |
Country Status (44)
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4874483B2 (ja) | 1999-06-09 | 2012-02-15 | ロバート イー. シーバース | 超臨界流体補助ネブライゼーション及びバブル乾燥 |
US6475468B2 (en) * | 2001-02-15 | 2002-11-05 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
CA2446904A1 (en) * | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
EG24184A (en) * | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
AU2003215396B2 (en) | 2002-02-25 | 2010-04-08 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
JP2006513139A (ja) * | 2002-07-03 | 2006-04-20 | ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド | 治療薬の全身性送達のための中央部気道投与 |
ES2280835T3 (es) * | 2002-12-19 | 2007-09-16 | Pharmacia Corporation | Formulacion no higroscopica que comprende un farmaco higroscopico. |
DE10338403A1 (de) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
EP2708225B1 (en) | 2004-04-23 | 2018-12-26 | CyDex Pharmaceuticals, Inc. | DPI Formulation Containing Sulfoalkyl Ether Cyclodextrin |
EA017982B1 (ru) | 2005-02-24 | 2013-04-30 | ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи | Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли |
WO2006095788A1 (ja) * | 2005-03-09 | 2006-09-14 | Ono Pharmaceutical Co., Ltd. | 粒子およびその粒子を含有する製剤 |
KR101152886B1 (ko) | 2005-10-26 | 2012-07-09 | 사이덱스 파마슈티칼스, 인크. | 설포알킬 에테르 시클로덱스트린 조성물 및 그의 제조 방법 |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
US20100269819A1 (en) * | 2006-08-14 | 2010-10-28 | Sievers Robert E | Human Powered Dry Powder Inhaler and Dry Powder Inhaler Compositions |
WO2008050847A1 (fr) * | 2006-10-25 | 2008-05-02 | Dainippon Sumitomo Pharma Co., Ltd. | Préparation granulaire non agglutinante |
EP1925295A1 (de) * | 2006-11-22 | 2008-05-28 | Boehringer Ingelheim Pharma GmbH & Co. KG | Stabile Pulverformulierung enthaltend ein Anticholinergikum |
WO2008136900A1 (en) | 2007-04-13 | 2008-11-13 | Diffusion Pharmaceuticals Llc | Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease |
US8206751B2 (en) | 2007-10-31 | 2012-06-26 | Diffusion Pharmaceuticals Llc | Class of therapeutics that enhance small molecule diffusion |
PL2432502T3 (pl) | 2009-05-20 | 2018-05-30 | Aeras | Trwałe, suszone rozpyłowo, immunogenne kompozycje wirusowe |
KR101782023B1 (ko) | 2009-06-22 | 2017-10-23 | 디퓨젼 파마슈티컬즈 엘엘씨 | 확산 촉진 화합물 및 그 화합물 단독 또는 혈전 용해제와 합쳐진 화합물의 용도 |
CN103124498A (zh) | 2010-06-02 | 2013-05-29 | 扩散药品有限公司 | 双极性反式类胡萝卜素的口服制剂 |
BR112014026957A8 (pt) | 2012-05-03 | 2018-01-16 | Janssen R&D Ireland | micropartícula, composição compreendendo a mesma, seu uso e sistema de distribuição nasal relacionados ao tratamento de infecções do trato respiratório superior |
WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
WO2015042352A1 (en) * | 2013-09-20 | 2015-03-26 | Virginia Commonwealth University | Delivery of particles using hygroscopic excipients |
DK3212212T3 (da) | 2014-10-31 | 2020-12-21 | Univ Monash | Pulverformulering |
CA3018550A1 (en) | 2016-03-24 | 2017-09-28 | Diffusion Pharmaceuticals Llc | Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3155573A (en) * | 1958-05-06 | 1964-11-03 | Benger Lab Ltd | Inhalant composition and method of making same |
EP0611567A1 (en) * | 1992-06-12 | 1994-08-24 | Teijin Limited | Ultrafine powder for inhalation and production thereof |
WO1996019197A1 (en) * | 1994-12-22 | 1996-06-27 | Astra Aktiebolag | Aerosol formulations of peptides and proteins |
WO1998031346A1 (en) * | 1997-01-16 | 1998-07-23 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
WO1999038493A1 (en) * | 1998-01-30 | 1999-08-05 | Rtp Pharma Inc. | Microparticle inhalation formulations |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
-
1999
- 1999-09-09 MA MA25762A patent/MA25590A1/fr unknown
- 1999-09-13 AP APAP/P/2001/002093A patent/AP1374A/en active
- 1999-09-13 TW TW088115876A patent/TWI226248B/zh not_active IP Right Cessation
- 1999-09-13 PL PL99346768A patent/PL195574B1/pl not_active IP Right Cessation
- 1999-09-13 BR BR9913722-4A patent/BR9913722A/pt not_active IP Right Cessation
- 1999-09-13 HN HN1999000159A patent/HN1999000159A/es unknown
- 1999-09-13 MY MYPI99003947A patent/MY129282A/en unknown
- 1999-09-13 AU AU60397/99A patent/AU753014B2/en not_active Ceased
- 1999-09-13 PE PE1999000925A patent/PE20001061A1/es not_active Application Discontinuation
- 1999-09-13 DZ DZ990192A patent/DZ2892A1/xx active
- 1999-09-13 CN CN99810871A patent/CN1317977A/zh active Pending
- 1999-09-13 CA CA002343920A patent/CA2343920A1/en not_active Abandoned
- 1999-09-13 IL IL14156299A patent/IL141562A0/xx not_active IP Right Cessation
- 1999-09-13 ID IDW20010582A patent/ID28845A/id unknown
- 1999-09-13 TR TR2001/01182T patent/TR200101182T2/xx unknown
- 1999-09-13 UA UA2001031707A patent/UA76085C2/uk unknown
- 1999-09-13 EE EEP200100151A patent/EE200100151A/xx unknown
- 1999-09-13 CZ CZ2001829A patent/CZ2001829A3/cs unknown
- 1999-09-13 AR ARP990104587A patent/AR022090A1/es unknown
- 1999-09-13 SK SK344-2001A patent/SK3442001A3/sk unknown
- 1999-09-13 NZ NZ510168A patent/NZ510168A/en unknown
- 1999-09-13 HU HU0103837A patent/HUP0103837A3/hu unknown
- 1999-09-13 EP EP99969035A patent/EP1117442A1/en not_active Withdrawn
- 1999-09-13 JP JP2000569846A patent/JP2002524535A/ja not_active Withdrawn
- 1999-09-13 YU YU24201A patent/YU24201A/sh unknown
- 1999-09-13 OA OA1200100063A patent/OA11781A/en unknown
- 1999-09-13 GE GEAP19995857A patent/GEP20043257B/en unknown
- 1999-09-13 WO PCT/US1999/021109 patent/WO2000015262A1/en not_active Application Discontinuation
- 1999-09-13 EA EA200100300A patent/EA003476B1/ru active IP Right Revival
- 1999-09-13 KR KR1020017003208A patent/KR20010075063A/ko not_active Application Discontinuation
- 1999-09-13 ZA ZA200101995A patent/ZA200101995B/en unknown
- 1999-09-14 PA PA19998481901A patent/PA8481901A1/es unknown
- 1999-09-14 TN TNTNSN99173A patent/TNSN99173A1/fr unknown
- 1999-09-14 CO CO99058265A patent/CO5130023A1/es unknown
- 1999-09-14 UY UY25711A patent/UY25711A1/es not_active Application Discontinuation
- 1999-09-14 GT GT199900156A patent/GT199900156A/es unknown
- 1999-10-31 SA SA99200718A patent/SA99200718B1/ar unknown
-
2001
- 2001-02-21 IL IL141562A patent/IL141562A/en unknown
- 2001-03-05 IS IS5878A patent/IS5878A/is unknown
- 2001-03-13 NO NO20011251A patent/NO20011251L/no not_active Application Discontinuation
- 2001-03-14 HR HR20010189A patent/HRP20010189A2/hr not_active Application Discontinuation
- 2001-03-14 LV LV010041A patent/LV12658B/xx unknown
- 2001-03-14 LT LT2001021A patent/LT4897B/lt not_active IP Right Cessation
- 2001-04-10 BG BG105430A patent/BG105430A/xx unknown
-
2002
- 2002-03-06 HK HK02101738.3A patent/HK1042231A1/zh unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3155573A (en) * | 1958-05-06 | 1964-11-03 | Benger Lab Ltd | Inhalant composition and method of making same |
EP0611567A1 (en) * | 1992-06-12 | 1994-08-24 | Teijin Limited | Ultrafine powder for inhalation and production thereof |
WO1996019197A1 (en) * | 1994-12-22 | 1996-06-27 | Astra Aktiebolag | Aerosol formulations of peptides and proteins |
WO1998031346A1 (en) * | 1997-01-16 | 1998-07-23 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
WO1999038493A1 (en) * | 1998-01-30 | 1999-08-05 | Rtp Pharma Inc. | Microparticle inhalation formulations |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP1374A (en) | Aerosolizable particles resistant to hygroscopic growth. | |
USRE37053E1 (en) | Particles incorporating surfactants for pulmonary drug delivery | |
US5855913A (en) | Particles incorporating surfactants for pulmonary drug delivery | |
CA2336139C (en) | Large porous particles emitted from an inhaler | |
US6652837B1 (en) | Preparation of novel particles for inhalation | |
US5985309A (en) | Preparation of particles for inhalation | |
CA2277801C (en) | Preparation of particles for inhalation | |
US7625865B2 (en) | Insulin highly respirable microparticles | |
ES2909080T3 (es) | Formulación de DPI que contiene sulfoalquil éter ciclodextrina | |
US6989155B1 (en) | Powders | |
JP4859320B2 (ja) | 改良された分散性を有する乾燥粉末組成物 | |
PL209876B1 (pl) | Sposób wytwarzania sproszkowanego preparatu do przyjmowania przez wdychanie, układ inhalowania proszkowego do przyjmowania przez wdychanie i zastosowanie liofilizowanej kompozycji do wytwarzania sproszkowanego preparatu do przyjmowania przez wdychanie | |
JP2003513031A5 (xx) | ||
CN111202722A (zh) | 一种洛匹那韦吸入干粉药物组合物及其制备方法 | |
Li et al. | The use of sodium carboxymethylcellulose in the preparation of spray-dried proteins for pulmonary drug delivery | |
Wang et al. | Characterization of a new inhalable thymopentin formulation | |
MXPA01002649A (en) | Dry powder active agent pulmonary delivery | |
Batycky et al. | The development of large porous particles for inhalation drug delivery | |
CA2403349C (en) | Preparation of particles for inhalation | |
EP1273290A1 (en) | Large porous particles emitted from an inhaler | |
EP1498115A1 (en) | Preparation of particles for inhalation |